Permanent rescue of lesioned neonatal motoneurons and enhanced axonal regeneration by adenovirus-mediated expression of glial cell-line-derived neurotrophic factor

Journal of Neuroscience Research

Volumn 54, Issue 6, 1998, Pages 766-777

  Baumgartner, Brian J ^a   Shine, H D ^a  

^a BAYLOR COLLEGE OF MEDICINE   (United States)

Author keywords

Facial nucleus; GDNF; Gene transfer; Peripheral nerve; Regeneration; Vibrissae

Indexed keywords

BETA GALACTOSIDASE; GLIAL CELL LINE DERIVED NEUROTROPHIC FACTOR; MESSENGER RNA;

ADENOVIRUS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; EXPRESSION VECTOR; FACIAL NERVE; GENE TRANSFER; MOTONEURON; NERVE CELL LESION; NERVE CELL NECROSIS; NERVE CRUSH; NERVE FIBER REGENERATION; NERVE TRANSECTION; NEUROPROTECTION; NEWBORN; NONHUMAN; PRIORITY JOURNAL; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; VIBRISSA;

ADENOVIRIDAE; ANIMALS; ANIMALS, NEWBORN; BETA-GALACTOSIDASE; FACIAL MUSCLES; FACIAL NERVE; GENE TRANSFER TECHNIQUES; GENETIC VECTORS; GLIAL CELL LINE-DERIVED NEUROTROPHIC FACTOR; MOTOR NEURONS; NERVE CRUSH; NERVE GROWTH FACTORS; NERVE REGENERATION; NERVE TISSUE PROTEINS; RATS; RNA, MESSENGER;

EID: 0032534698     PISSN: 03604012     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-4547(19981215)54:6<766::AID-JNR4>3.0.CO;2-A     Document Type: Article

References (55)

1. Baumgartner BJ, Shine HD. 1997. Targeted transduction of CNS neurons with adenoviral vectors carrying neurotrophic genes confers neuroprotection that exceeds the transduced population. J Neurosci 17:6504-6511.
2. Baumgartner BJ, Shine HD. 1998. Neuroprotection of spinal motoneurons following targeted transduction with an adenoviral vector carrying the gene for glial cell-line derived neurotrophic factor. Exp Neurol 153:102-112.
3. Beuche W, Friede RL. 1984. The role of non-resident cells in Wallerian degeneration. J Neurocytol 13:767-796.
4. Bunge RP. 1994. The role of the Schwann cell in trophic support and regeneration. J Neurol 241:s19-s21.
5. Caroni P, Grandes P. 1990. Nerve sprouting in innervated adult skeletal muscle induced by exposure to elevated levels of insulin-like growth factors. J Cell Biol 110:1307-1317.
6. Curtis R, Adryan KM, Zhu Y, Harkness PJ, Lindsay RM, DiStefano PS. 1993. Retrograde axonal transport of ciliary neurotrophic factor is increased by peripheral nerve injury. Nature 365:253-255.
7. DiStefano PS, Friedman B, Radziejewski C, Alexander C, Boland P, Schick CM, Lindsay RM, Wiegand SJ. 1992. The neurotrophins BDNF, NT-3, and NGF display distinct patterns of retrograde axonal transport in peripheral and central neurons. Neuron 8:983-993.
8. Eriksson NP, Lindsay RM, Aldskogius H. 1994. BDNF and NT-3 rescue sensory but not motoneurons following axotomy in the neonate. Neuroreport 5:1445-1448.
9. Finiels F, Giménez y Ribotta M, Barkats M, Samolyk M-L, Robert J-J, Privat A, Revah F, Mallet J. 1995. Specific and efficient gene transfer strategy offers new potentialities for the treatment of motor neurone disease. Neuroreport 7:373-378.
10. Frisén J. 1997. Determinants of axonal regeneration. Histol Histopathol 12:857-868.
11. Fu SY, Gordon T. 1997. The cellular and molecular basis of peripheral nerve regeneration. Mol Neurobiol 14:67-116.
12. Ghadge GD, Roos RP, Kang UJ, Wollmann R, Fishman PS, Kalynych AM, Barr E, Leiden JM. 1995. CNS gene delivery by retrograde transport of recombinant replication-defective adenoviruses. Gene Ther 2:132-137.
13. Giménez y Ribotta M, Revah F, Pradier L, Loquet I, Mallet J, Privat A. 1997. Prevention of motoneuron death by adenovirus-mediated neurotrophic factors. J Neurosci Res 48:281-285.
14. Gorio A, Vergani L, de Tollis A, di Giulio AM, Torsello A, Cattaneo L, Muller EE. 1997. Muscle reinnervation following neonatal nerve crush. Interactive effects of glycosaminoglycans and insulin-like growth factor-1. Neuroscience 82:1029-1037.
15. Gravel C, Götz R, Lorrain A, Sendtner M. 1997. Adenoviral gene transfer of ciliary neurotrophic factor and brain-derived neurotrophic factor leads to long-term survival of axotomized motor neurons. Nature Med 3:765-770.
16. Gurney ME, Yamamoto H, Kwon Y. 1992. Induction of motor neuron sprouting in vivo by ciliary neurotrophic factor and basic fibroblast growth factor. J Neurosci 12:3241-3247.
17. Hammarberg H, Piehl F, Cullheim S, Fjell J, Hökfelt T, Fried K. 1996. GDNF mRNA in Schwann cells and DRG satellite cells after chronic sciatic nerve injury. Neuroreport 7:857-860.
18. Henderson CE, Phillips HS, Pollock RA, Davies AM, Lemeulle C, Armanini M, Simmons L, Moffet B, Vandlen RA, Koliatsos VE, Rosenthal A. 1994. GDNF: A potent survival factor for motoneurons present in peripheral nerve and muscle. Science 266:1062-1064.
19. Ide C. 1996. Peripheral nerve regeneration. Neurosci Res 25:101-121.
20. Ip NY, Yancopoulos GD. 1994. Neurotrophic factors and their receptors. Ann Neurol 35 Suppl:S13-6.
21. Kashihara Y, Kuno M, Miyata Y. 1987. Cell death of axotomized motoneurones in neonatal rats, and its prevention by peripheral reinnervation. J Physiol 386:135-148.
22. Klein BG, Rhoades RW. 1985. Representation of whisker follicle intrinsic musculature in the facial motor nucleus of the rat. J Comp Neurol 232:55-69.
23. Kwon YW, Gurney ME. 1994. Systemic injections of ciliary neurotrophic factor induce sprouting by adult motor neurons. Neuroreport 5:789-792.
24. Laird JMA, Mason GS, Thomas KA, Hargreaves RJ, Hill RG. 1995. Acidic fibroblast growth factor stimulates motor and sensory axon regeneration after sciatic nerve crush in the rat. Neuroscience 65:209-216.
25. Levi-Montalcini R, Angeletti PU. 1968. Nerve growth factor. Physiol Rev 48:534-569.
26. Lewin SL, Utley DS, Cheng ET, Verity AN, Terris DJ. 1997. Simultaneous treatment with BDNF and CNTF after peripheral nerve transection and repair enhances rate of functional recovery compared with BDNF treatment alone. Laryngoscope 107:992-999.
27. Lindsay RM, Wiegand SJ, Altar CA, DiStefano PS. 1994. Neurotrophic factors: From molecule to man. Trends Neurosci 17:182-190.
28. Matheson CJ, Wang J, Collins FD, Yan Q. 1997. Long-term survival effects of GDNF on neonatal rat facial motoneurons after axotomy. Neuroreport 8:1739-1742.
29. Naveilhan P, ElShamy WM, Ernfors P. 1997. Differential regulation of mRNAs for GDNF and its receptors Ret and GDNFRα after sciatic nerve lesion in the mouse. Eur J Neurosci 9:1450-1460.
30. Newman JP, Verity AN, Hawatmeh S, Fee WE, Terris DJ. 1996. Ciliary neurotrophic factor enhances peripheral nerve regeneration. Arch Otolaryngol Head Neck Surg 122:399-403.
31. Nguyen QT, Parsadanian ASh, Snider WD, Lichtman JW. 1998. Hyperinnervation of neuromuscular junctions caused by GDNF overexpression in muscle. Science 279:1725-1729.
32. Oppenheim RW. 1996. The concept of uptake and retrograde transport of neurotrophic molecules during development: History and present status. Neurochem Res 21:769-777.
33. Perry VH, Brown MC. 1992. Role of macrophages in peripheral nerve degeneration and repair. Bioessays 14:401-406.
34. Popovic M, Bresjanac M, Sketelj J. 1994. Regenerating axons enhance differentiation of perineurial-like cells involved in minifascicle formation in the injured peripheral nerve. J Neuropathol Exp Neurol 53:590-597.
35. Richardson PM. 1991. Neurotrophic factors in regeneration. Curr Opin Neurobiol 1:401-406.
36. Röyttä M, Salonen V. 1988. Long-term endoneurial changes after nerve transection. Acta Neuropathol 76:35-45.
37. Salonen V, Aho H, Röyttä M, Peltonen J. 1988. Quantitation of Schwann cells and endoneurial fibroblast-like cells after experimental nerve trauma. Acta Neuropathol 75:331-336.
38. Sariola H, Sainio K, Arumae U, Saarma M. 1994. Neurotrophins and ciliary neurotrophic factor: Their biology and pathology. [Review]. Ann Med 26:355-363.
39. Schmalbruch H. 1984. Motoneuron death after sciatic nerve section in newborn rats. J Comp Neurol 224:252-258.
40. Schmalbruch H, Rosenthal A. 1995. Neurotrophin-4/5 postpones the death of injured spinal motoneurons in newborn rats. Brain Res 700:254-260.
41. Seddon HJ. 1943. Three types of nerve injury. Brain 66:17-288.
42. Semba K, Egger MD. 1986. The facial "motor" nerve of the rat: Control of vibrissal movement and examination of motor and sensory components. J Comp Neurol 247:144-158.
43. Semba K, Komisaruk BR. 1984. Neural substrates of two different rhythmical vibrissal movements in the rat. Neuroscience 12:761-774.
44. Sendtner M, Carroll P, Holtmann B, Hughes RA, Thoenen H. 1994. Ciliary neurotrophic factor. J Neurobiol 25:1436-1453.
45. Sendtner M, Kreutzberg GW, Thoenen H. 1990. Ciliary neurotrophic factor prevents the degeneration of motor neurons after axotomy. Nature 345:440-441.
46. Sendtner M, Schmalbruch H, Stockli KA, Carroll P, Kreutzberg GW, Thoenen H. 1992. Ciliary neurotrophic factor prevents degeneration of motor neurons in mouse mutant progressive motor neuronopathy. Nature 358:502-504.
47. Snider WD, Elliott JL, Yan Q. 1992. Axotomy-induced neuronal death during development. J Neurobiol 23:1231-1246.
48. Thoenen H. 1991. The changing scene of neurotrophic factors. Trends Neurosci 14:165-170.
49. Thomas P, Jones DG. 1967. The cellular response to nerve injury. 2. Regeneration of the perineurium after nerve section. J Anat 101:45-55.
50. Trupp M, Rydén M, Jörnvall H, Funakoshi H, Timmusk T, Arenas E, Ibáñez CF. 1995. Peripheral expression and biological activities of GDNF, a new neurotrophic factor for avian and mammalian peripheral neurons. J Cell Biol 130:137-148.
51. Vejsada R, Sagot Y, Kato AC. 1995. Quantitative comparison of the transient rescue effects of neurotrophic factors on axotomized motoneurons in vivo. Eur J Neurosci 7:108-115.
52. Welker WI. 1964. Analysis of sniffing of the albino rat. Behaviour 22:223-244.
53. Yan Q, Elliott J, Snider WD. 1992. Brain-derived neurotrophic factor rescues spinal motor neurons from axotomy-induced cell death. Nature 360:753-755.
54. Yan Q, Matheson C, Lopez OT. 1995. In vivo neurotrophic effects of GDNF on neonatal and adult facial motor neurons. Nature 373:341-344.
55. Zurn AD, Baetge EE, Hammang JP, Tan SA, Aebischer P. 1994. Glial cell line-derived neurotrophic factor (GDNF), a new neurotrophic factor for motoneurones. Neuroreport 6:113-118.