Bistability in the Ca2+/calmodulin-dependent protein kinase-phosphatase system

Biophysical Journal

Volumn 79, Issue 5, 2000, Pages 2211-2221

  Zhabotinsky, Anatol M ^a  

^a BRANDEIS UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM; PHOSPHATASE; PROTEIN KINASE (CALCIUM,CALMODULIN);

ARTICLE; AUTOPHOSPHORYLATION; CALCIUM CURRENT; DEPHOSPHORYLATION; ENZYME PHOSPHORYLATION; ENZYME STABILITY; LONG TERM POTENTIATION; MATHEMATICAL MODEL; MICHAELIS CONSTANT; NERVE CELL;

EID: 0033748154     PISSN: 00063495     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-3495(00)76469-1     Document Type: Article

References (64)

1. Regulatory phosphorylation of AMPA-type glutamate receptors by CaMKII during long-term potentiation
2. A synaptic basis for memory storage in the cerebral cortex
3. Synaptic plasticity: LTP and LTD
4. Inhibitory effect of marine-sponge toxin, okadaic acid, on protein phosphatases
5. A synaptic model of memory: Long-term potentiation in the hippocampus
6. The multifunctional calcium/calmodulin-dependent protein kinase: From form to function
7. Site-selective autophosphorylation of Ca2+/calmodulin-dependent protein kinase II as a synaptic encoding mechanism
8. Sensitivity of CaM kinase II to the frequency of Ca2+ oscillations
9. A mechanism for synaptic frequency detection through autophosphorylation of CaM kinase-II
10. Multiple structural elements define the specificity of recombinant human inhibitor-1 as a protein phosphatase-1 inhibitor
11. 2+/calmodulin-dependent protein kinase in rat brain
12. 2+/calmodulin-dependent protein kinase II from hog gastric mucosa using a protein-protein affinity chromatographic technique
13. 2+/calmodulin-dependent protein-kinase-II and its endogenous substrates in the induction of long-term potentiation
14. Decreased protein phosphatase 2A activity in hippocampal long-term potentiation
15. 2+/calmodulin-dependent protein-kinase-II
16. αCaMKII binding to the C-terminal tail of NMDA receptor subunit NR2A and its modulation by autophosphorylation
17. 286 of the α calcium-calmodulin kinase II in LTP and learning
18. Ca2+/calmodulin-dependent protein kinase-II from hen brain - Purification and characterization
19. Dual role of calmodulin in autophosphorylation of multifunctional CaM kinase may underlie decoding of calcium signals
20. 2+/calmodulin-dependent protein kinases
21. Dendritic spines: Cellular specialization and imparting both stability and flexibility to synaptic function
22. Ca2+ buffering and action potential-evoked Ca2+ signaling in dendrites of pyramidal neurons
23. 2+ to calmodulin for activation
24. Long-lasting forms of synaptic potentiation in the mammalian hippocampus
25. 2+/calmodulin-dependent protein kinase II
26. Effects of phosphorylation of protein phosphatase 1 by pp60(v-src) on the interaction of the enzyme with substrates and inhibitor proteins
27. Firing rhythmicity in the neocortex in vivo and in vitro under sustained iontophoretic excitation
28. Signal transduction molecules at the glutamatergic postsynaptic membrane
29. A calcium/calmodulin-dependent protein kinase from mammalian brain that phosphorylates synapsin I: Partial purification and characterization
30. 2+/calmodulin-dependent protein kinase phosphatase
31. Decoding time-varying calcium signals by the postsynaptic biochemical network: Computer simulations of molecular kinetics
32. 2+/calmodulin-dependent protein kinase from rat brain
33. Calcium/calmodulin-dependent protein kinase II is associated with the N-methyl-D-aspartate receptor
34. Long-term synaptic depression in the mammalian brain
35. A mechanism for memory storage insensitive to molecular turnover: A bistable autophosphorylating kinase
36. The CaM kinase II hypothesis for the storage of synaptic memory
37. 2+/calmodulin-dependent protein kinase molecules of the postsynaptic density
38. Learning mechanisms: The case for CaMKII
39. A synaptically controlled, associative signal for Hebbian plasticity in hippocampal neurons
40. Mechanisms of calcium decay kinetics in hippocampal spines: Role of spine calcium pumps and calcium diffusion through the spine neck in biochemical compartmentalization
41. Neuroscience: Long-term potentiation - A decade of progress?
42. 2+/calmodulin-dependent protein kinase II in synapses
43. 2+/calmodulin-dependent protein kinase II with neuronal cytoskeletal proteins
44. CaM kinase: A model for its activation and dynamics
45. 2+-triggered molecular switch
46. Regulation of Ca2+/calmodulin-dependent protein kinase by inter- and intrasubunit-catalyzed autophosphorylations
47. Involvement of a calcineurin/inhibitor-1 phosphatase cascade in hippocampal long-term depression
48. The threshold condition for initiation of action potentials by excitable cells
49. Switching characteristics of a model for biochemical-reaction networks describing autophosphorylation versus dephosphorylation of Ca2+/calmodulin-dependent protein kinase II
50. Visualization of the distribution of autophosphorylated calcium calmodulin-dependent protein kinase II after tetanic stimulation in the CA1 area of the hippocampus
51. All-or-none potentiation at CA3-CA1 synapses
52. Dynamic control of CaMKII translocation and localization in hippocampal neurons by NMDA receptor stimulation
53. Protein phosphatases - Recent progress
54. Calcium-dependent protein kinases in learning and memory
55. Dual calcium ion regulation of calcineurin by calmodulin and calcineurin B
56. Translocation of autophosphorylated calcium/calmodulin-dependent protein kinase II to the postsynaptic density
57. Autophosphorylation-dependent targeting of calcium/calmodulin-dependent protein kinase II by the NR2B subunit of the N-methyl-D-aspartate receptor
58. 2+/calmodulin-dependent protein kinase II into postsynaptic density after decapitation
59. 2+], elevation
60. Protein phosphatase 1 is involved in the dissociation of Ca2+/calmodulin-dependent protein kinase II from postsynaptic densities
61. Mechanisms of calcium influx into hippocampal spines: Heterogeneity among spines, coincidence detection by NMDA receptors, and optical quantal analysis
62. Changes in phosphorylation of Ca2+/calmodulin-dependent protein kinase II (CaMKII) in processing of short-term and long-term memories after passive avoidance learning
63. Enlightening the postsynaptic density