A mechanism for synaptic frequency detection through autophosphorylation of CaM kinase II

Biophysical Journal

Volumn 70, Issue 6, 1996, Pages 2493-2501

  Dosemeci, A ^a,b   Albers, R W ^a  

^a NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE   (United States)

^b NATIONAL INSTITUTES OF HEALTH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN KINASE (CALCIUM,CALMODULIN);

ARTICLE; AUTOPHOSPHORYLATION; CALCIUM TRANSPORT; COMPUTER MODEL; COMPUTER PROGRAM; ENZYME PHOSPHORYLATION; ENZYME REGULATION; ENZYME SUBUNIT; POSTSYNAPTIC POTENTIAL; SYNAPSE;

EID: 0030058273     PISSN: 00063495     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-3495(96)79821-1     Document Type: Article

References (40)

1. Bear, M. F. and R. C. Malenka. 1994. Synaptic plasticity: LTP and LTD. Curr. Opin. Neurobiol. 4:389-399.
2. Brickey, D. A., J. G. Bann, Y.-L. Fong, L. Perrino, R. G. Brennan, and T. R. Soderling. 1994. Mutational analysis of the autoinhibitory domain of calmodulin kinase II. J. Biol. Chem. 269:29047-29054.
3. Colbran, R. J., Y. L. Fong, C. M. Schworer, and T. R. Soderling. 1988. Regulatory interactions of the calmodulin-binding, inhibitory, and autophosphorylation. J. Biol. Chem. 263:18145-18151.
4. 2+/ calmodulin-dependent protein kinase. J. Biol. Chem. 269:31330-31333.
5. Dosemeci, A., and T. S. Reese. 1993. Inhibition of endogenous phosphatase in postsynaptic density fraction allows extensive phosphorylation of the major postsynaptic density protein. J. Neurochem. 61: 550-555.
6. Dudek, S. M., and M. F. Bear. 1992. Homosynaptic long-term depression in area CA1 of hippocampus and effects of N-methyl-D-aspartate receptor blockade. Proc. Natl. Acad. Sci. USA. 89:4363-4367.
7. Dudek, S. M., and M. F. Bear. 1993. Bidirectional long-term modification of synaptic effectiveness in the adult and immature hippocampus. J. Neurosci. 13:2910-2918.
8. 2+/calmodulin-dependent protein kinase in rat brain. J. Neurosci. 5:3270-3277.
9. 2+/calmodulin-dependent protein kina and various tissues. J. Neurochem. 51:1070-1078.
10. 2+Vcalmodulin-dependent protein kinase II. J. Biol. Chem. 268:7863-7867.
11. Gamble, E., and C. Koch. 1987. The dynamics of free calcium in dendritic spines in response to repetitive synaptic input. Science. 236:1311-1315.
12. 2+/calmodulin-dependent protein kinase and mutational analysis of its auloregulation. Neuron. 3:59-70.
13. Hanson, P. I., T. Meyer, L. Stryer, and H. Schulman. 1994. Dual role of calmodulin in autophosphorylation of multifunctional CaM kinase may underlie decoding of calcium signals. Neuron. 12:943-956.
14. 2+/calmodulin-dependent analyzed by site-directed mutagenesis. J. Biol. Chem. 267:17216-17224.
15. Huang, Y. Y., A. Colino, D. K. Selig, and R. C. Malenka. 1992. The influence of prior synaptic activity on the induction of long-term potentiation. Science. 255:730-733.
16. 2+/calmodulin-independent activity of calmodulin-dependent protein kinase II by autophosphorylation. Autothiophosphorylation of the enzyme. J. Biol. Chem. 266:11582-11588.
17. Ito, I., H. Hidaka, and H. Sugiyama. 1991. Effects of KN-62, a specific inhibitor of calcium/calmodulin-dependent protein kinase II, on long-term potentiation in the rat hippocampus. Neurosci. Lett. 121:119-121.
18. 2+/calmodulin-dependent protein kinase II revealed by electron microscopy. J. Cell Biol. 115:1049-1060.
19. 2+/ calmodulin-dependent protein kinase. Proc. Natl. Acad. Sci. USA. 81: 945-949.
20. Kennedy, M. B., M. K. Bennett, and N. E. Erondu. 1983. Biochemical and immunochemical evidence that the major postsynaptic density protein is a subunit of a calmodulin-dependent protein kinase. Proc. Natl. Acad. Sci. USA. 80:7357-7361.
21. 2+/calmodulin-independent autophosphorylation. J. Biol. Chem. 263:19232-19239.
22. Lisman, J. 1989. A mechanism for the Hebb and the anti-Hebb processes underlying learning and memory. Proc. Natl. Acad. Sci. USA. 86: 9574-9578.
23. 2+/calmodulin-dependent protein kinase molecules of the postsynaptic density. Proc. Natl. Acad. Sci. USA. 85:5320-5324.
24. Lou, L. L., and H. Schulman. 1989. Distinct autophosphorylation sites sequentially produce autonomy and inhibition of the multifunctional Ca2+/calmodulin-dependent protein kinase. J. Neurosci. 9:2020-2032.
25. Malenka, R. C. 1994. Multiple forms of NMDA receptor-dependent synaptic plasticity in the hippocampus. In Long-Term Potentiation, vol. 2. M. Baudry and J. L. Davis, editors. MIT Press, Cambridge, MA. 121-141.
26. Malenka, R. C., J. A. Kauer, D. J. Perkel, M. D. Mauk, P. T. Kelly, R. A. Nicoll, and M. N. Waxham. 1989. An essential role for postsynaptic calmodulin and protein kinase activity in long-term potentiation. Nature. 340:554-557.
27. Malenka, R. C., and R. A. Nicoll. 1993. NMDA-receptor-dependent synaptic plasticity: multiple forms and mechanisms. Trends Neurosci. 16: 521-527.
28. Malinow, R., H. Schulman, and R. W. Tsien. 1989. Inhibition of postsynaptic PKC or CaMKII blocks induction but not expression of LTP. Science. 245:862-866.
29. Mayford, M., J. Wang, E. R. Kandel, and T. J. O'Dell. 1995. CaMKII regulates the frequency-response function of hippocampal synapses for the production of both LTD and LTP. Cell. 81:891-904.
30. Meyer, T., P. I. Hanson, L. Stryer, and H. Schulman. 1992. Calmodulin trapping by calcium-calmodulin-dependent protein kinase. Science. 256: 1199-1202.
31. 2+-triggered molecular switch. Cell. 44:861-870.
32. 2+/calmodulin-dependent protein kinase II by inter- and intrasubunit-catalyzed autophosphorylations. J. Biol. Chem. 269:13744-13747.
33. Mulkey, R. M., S. Endo, S. Shenolikar, and R. C. Malenka. 1994. Involvement of a calcineurin/inhibitor-1 phosphatase cascade in hippocampal long-term depression. Nature. 369:486-488.
34. Mulkey, R. M., C. E. Herron, and R. C. Malenka. 1993. An essential role for protein phosphatases in hippocampal long-term depression. Science. 261:1051-1055.
35. Mulkey, R. M., and R. C. Malenka. 1992. Mechanisms underlying induction of homosynaptic long-term depression in area CA1 of the hippocampus. Neuron. 9:967-975.
36. Ouimet, C. C., T. L. McGuinness. and P. Greengard. 1984. Immunocytochemical localization of calcium/calmodulin-dependent protein kinase II in rat brain. Proc. Natl. Acad. Sci. USA. 81:5604-5608.
37. 2+/calmodulin is inhibited by autophosphorylation of threonine within the calmodulin-binding domain. J. Biol. Chem. 265:11204-11212.
38. Pettit, D. L., S. Perlman, and R. Malinow. 1994. Potentiated transmission and prevention of further LTP by increased CaMKII activity in postsynaptic hippocampal slice neurons. Science. 266:1881-1885.
39. Silva, A. J., C. F. Stevens, S. Tonegawa, and Y. Wang. 1992. Deficient hippocampal long-term potentiation in α-calcium-calmodulin kinase II mutant mice. Science. 257:201-206.
40. Stevens, C. F., S. Tonegawa, and Y. Wang. 1994. The role of calcium-calmodulin kinase II in three forms of synaptic plasticity. Curr. Biol. 4:687-693.