Requirement of heat shock protein 90 in mesangial cell mitogenesis

Kidney International

Volumn 58, Issue 6, 2000, Pages 2377-2389

  Pieper, Michael ^a,b   Rupprecht, Harald D ^a,b   Bruch, Katja M ^a,b   De Heer, Emile ^a,b   Schücklmann, Harald O ^a,b  

^a UNIVERSITY HOSPITAL ERLANGEN   (Germany)

^b LEIDEN UNIVERSITY   (Netherlands)

Author keywords

Cell cycle; Geldanamycin; Glomerulonephritis; Hyperplasia; Injury; Proliferation of cells; Protein folding; Renal scarring

Indexed keywords

COMPLEMENTARY DNA; DNA; GELDANAMYCIN; HEAT SHOCK PROTEIN 90; MITOGEN ACTIVATED PROTEIN KINASE; STAT1 PROTEIN; TRANSCRIPTION FACTOR;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL CYCLE G1 PHASE; CELL CYCLE G2 PHASE; CELL CYCLE S PHASE; CELL HYPERPLASIA; CONTROLLED STUDY; DNA REPLICATION; DNA SYNTHESIS; ENZYME ACTIVITY; GLOMERULONEPHRITIS; MALE; MESANGIUM CELL; MITOGENESIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN FOLDING; PROTEIN LOCALIZATION; RAT;

EID: 0033662061     PISSN: 00852538     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1523-1755.2000.00421.x     Document Type: Article

References (42)

1. Cell renewal of glomerular cell types in normal rats. An autoradiographic analysis
2. The contribution of glomerular mesangial cells to progressive glomerulosclerosis
3. Inhibition of mesangial cell proliferation and matrix expansion in glomerulonephritis in the rat by antibody to platelet-derived growth factor
4. Heparin suppresses mesangial cell proliferation, and matrix expansion in experimental mesangioproliferative glomerulonephritis
5. Direct in vivo inhibition of the nuclear cell cycle cascade in experimental mesangial proliferative glomerulonephritis with Roscovitine, a novel cyclin-dependent kinase antagonist
6. Factors controlling growth and matrix production in vascular smooth muscle and glomerular mesangial cells
7. Heat-shock proteins, molecular chaperones, and the stress response: Evolutionary and ecological physiology
8. Hsp90: A holding for folding
9. Murine 86- and 84-kDa heat shock proteins, cDNA sequences, chromosome assignments, and evolutionary origins
10. Maturation of the tyrosine kinase c-src as a kinase and as a substrate depends on the molecular chaperone Hsp 90
11. Destabilization of Raf-1 by geldanamycin leads to disruption of the Raf-1-MEK-mitogen-activated protein kinase signalling pathway
12. Disruption of the Raf-1-Hsp90 molecular complex results in destabilization of Raf-1 and loss of Raf-1-Ras association
13. Mammalian p50Cdc37 is a protein kinase-targeting subunit of Hsp 90 that binds and stabilizes Cdk4
14. Calmodulin is essential for cyclin-dependent kinase 4 activity and nuclear accumulation of cyclin D1-Cdk 4 during G1
15. Preclinical pharmacologic evaluation of geldanamycin as an antitumor agent
16. Effects of the tyrosine-kinase inhibitor geldanamycin on ligand-induced Her-2/neu activation, receptor expression and proliferation of Her-2-positive malignant cell lines
17. Crystal structure of an Hsp90-geldanamycin complex: Targeting of a protein chaperone by an antitumor agent
18. Localization of 90-kDa heat shock protein in the kidney
19. Induction and intracellular localization of 90-kilodalton heat-shock protein in rat kidneys with acute gentamicin nephropathy
20. Glomerulonephritis induced by monoclonal anti-Thy 1.1 antibodies: A sequential histological and ultrastructural study in the rat
21. Identifying differences in mRNA expression by representational difference analysis of cDNA
22. Expression of the transcriptional regulator Egr-1 in experimental glomerulonephritis: Requirement for mesangial cell proliferation
23. Effect of vasoactive agents on induction of Egr-1 in rat mesangial cells: Correlation with mitogenicity
24. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction
25. A rapid micropreparation technique for extraction of DNA-binding proteins from limiting numbers of mammalian cells
26. Interleukin-3, granulocyte-macrophage colony stimulating factor and interleukin-5 transduce signals through two STAT5 homologs
27. STAT activation by the PDGF receptor requires juxtamembrane phosphorylation sites but not Src tyrosine kinase activation
28. PDGF stimulates tyrosine phosphorylation of JAK 1 protein tyrosine kinase in human mesangial cells
29. Mycophenolic acid: A new approach to the therapy of experimental mesangial proliferative glomerulonephritis
30. Screening for genes up-regulated in 5/6 nephrectomized mouse kidney
31. Induction and altered localization of 90-kDa heat-shock protein in rat kidneys with cisplatin-induced acute renal failure
32. Induction of heat-shock proteins HSP73 and HSP90 in rat kidneys after ischemia
33. Transcriptional regulation of the heat shock protein genes by STAT family transcription factors
34. Signal transducer and activator of transcription-1 and heat shock factor-1 interact and activate the transcription of the Hsp-70 and Hsp-90β gene promoters
35. The hsp90-binding antibiotic geldanamycin decreases Raf levels and epidermal growth factor signaling without disrupting formation of signaling complexes or reducing the specific enzymatic activity of Raf kinase
36. A common nuclear signal transduction pathway activated by growth factor and cytokine receptors
37. Inducible binding of a factor to the c-fos regulatory region
38. PDGF-induced Egr-1 expression in rat mesangial cells is mediated through upstream serum response elements
39. Physical interaction of mammalian CDC37 with CDK4
40. The role of the 90-kDa heat shock protein in cell cycle control and differentiation of the monoblastoid cell line U937
41. Expression of heat shock proteins in mouse skin during wound healing
42. Increased heat shock protein 90 expression leads to increased apoptosis in the monoblastoid cell line U937 following induction with TNF-α and cycloheximide: A possible role in immunopathology