In vitro selection of a ligase ribozyme carrying alkylamino groups in the side chains

Bioconjugate Chemistry

Volumn 11, Issue 6, 2000, Pages 744-748

  Teramoto, N ^a   Imanishi, Y ^b   Ito, Y ^c  

^a KYOTO UNIVERSITY   (Japan)

^b NARA INSTITUTE OF SCIENCE AND TECHNOLOGY   (Japan)

^c UNIVERSITY OF TOKUSHIMA   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ADENINE; DNA TEMPLATE; IN VITRO SELECTION; LIGASE; OLIGONUCLEOTIDE; RIBOZYME; RNA LIBRARY;

OLIGONUCLEOTIDES;

ALKYLAMINO GROUP; DNA-OLIGONUCLEOTIDES; IN-VITRO; LIGASE RIBOZYME; PHOSPHODIESTER BONDS; RANDOM SEQUENCE; RATE ACCELERATION; SIDE-CHAINS; VITRO SELECTION;

RNA;

EID: 0033658253     PISSN: 10431802     EISSN: None     Source Type: Journal    
DOI: 10.1021/bc990146r     Document Type: Article

References (35)

1. In vitro selection of catalytic polynucleotides
2. Isolation of new ribozymes from a large pool of random sequences
3. Isolation of novel ribozymes that ligate AMP-activated RNA substrates
4. A DNA metallo-enzyme with DNA ligase activity
5. Selection of RNA amide synthases
6. Aminoacyl-RNA synthesis catalyzed by an RNA
7. Ribozyme-catalyzed amino-acid transfer reactions
8. Peptide bond formation by in vitro selected ribozymes
9. A novel ribozyme with ester transferase activity
10. Porphyrin metalation catalyzed by a small RNA molecule
11. A catalytic DNA for porphyrin metalation
12. In vitro evolution of a self-alkylating ribozyme
13. RNA-catalyzed carbon-carbon bond formation
14. RNA-catalyzed nucleotide synthesis
15. Novel and variant ribozymes obtained through in vitro selection
16. Prospects for understanding the origin of the RNA world
17. New uridine derivatives for systematic evolution of RNA ligands by exponential enrichment
18. Expanding the potential of DNA for binding and catalysis: Highly functionalized dUTP derivatives that are substrates for thermostable DNA polymerase
19. Modified nucleic acid for systematic evolution of RNA ligands by exponential enrichment
20. Detection of DNA targets with biotinylated and fluoresceinated RNA probes
21. Randomization of genes by PCR mutagenesis
22. On finding all suboptimal foldings of an RNA molecule
23. Predicting optimal and suboptimal secondary structure for RNA
24. Kinetics and mechanistic analysis of nonenzymatic, template-directed oligoribonucleotide ligation
25. In vitro selection of ligase ribozymes containing 2'-amino groups
26. Site-specific modification of Pre-mRNA: The 2'-hydroxyl groups at the splice sites
27. Regioselective ligation of oligoribonucleotides using DNA splints
28. Comprehensive analysis of hydrogen Bonds in regulatory protein DNA-complexes: In search of common principles
29. Complementary sets of noncanonical base pairs mediate RNA helix packing in the group I intron active site
30. A preorganized active site in the crystal structure of the Tetrahymena ribozyme
31. Crystal structure of a hepatitis delta virus ribozyme
32. Interdomein cross-linking and molecular modeling of the hairpin ribozyme
33. A minor groove RNA triple helix within the catalytic core of a group I intron
34. Emergence of a dual-catalytic RNA with metal-specific cleavage and ligase activities: The spandrels of RNA evolution
35. A ribozyme that lacks cytidine