Corneal epithelial tight junctions and their response to lipopolysaccharide challenge

Investigative Ophthalmology and Visual Science

Volumn 41, Issue 13, 2000, Pages 4093-4100

  Yi, X J ^a   Wang, Y ^a   Yu, F S X ^a  

^a SCHEPENS EYE RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CLAUDIN 1; LIPOPOLYSACCHARIDE; MEMBRANE PROTEIN; OCCLUDIN; PROTEIN ZO1; PROTEIN ZO2; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL CULTURE; CELL MEMBRANE PERMEABILITY; CELL PROTECTION; CELLULAR DISTRIBUTION; CONTROLLED STUDY; CORNEA EPITHELIUM; IMMUNOBLOTTING; IMMUNOCYTOCHEMISTRY; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TIGHT JUNCTION;

ANIMALS; CELLS, CULTURED; DNA PRIMERS; DOSE-RESPONSE RELATIONSHIP, DRUG; ELECTRIC IMPEDANCE; EPITHELIUM, CORNEAL; FLUORESCENT ANTIBODY TECHNIQUE, INDIRECT; IMMUNOBLOTTING; LIPOPOLYSACCHARIDES; MEMBRANE PROTEINS; PERMEABILITY; PHOSPHOPROTEINS; PSEUDOMONAS AERUGINOSA; RATS; RATS, SPRAGUE-DAWLEY; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA; RNA, MESSENGER; TIGHT JUNCTIONS; TIME FACTORS;

EID: 0033653266     PISSN: 01460404     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (57)

1. Cell biology of the corneal epithelium
2. ZO1 in corneal epithelium: Association to the zonula occludens and adherens junctions
3. ZO-1 in corneal epithelium; stratal distribution and synthesis induction by outer cell removal
4. Molecular analyses of tight junction physiology: Insights and paradoxes
5. Understanding tight junction clinical physiology at the molecular level
6. Identification of ZO-1: A high molecular weight polypeptide associated with the tight junction (zonula occludens) in a variety of epithelia
7. Occludin: A novel integral membrane protein localizing at tight junctions
8. Structural and signalling molecules come together at tight junctions
9. Transmembrane proteins in the tight junction barrier
10. Occludin and the functions of tight junctions
11. Occludin-deficient embryonic stem cells can differentiate into polarized epithelial cells bearing tight junctions
12. A single gene product, claudin-1 or -2, reconstitutes tight junction strands and recruits occludin in fibroblasts
13. Claudin multigene family encoding four-transmembrane domain protein components of tight junction strands
14. Manner of interaction of heterogeneous claudin species within and between tight junction strands
15. Characterization of ZO-1, a protein component of the tight junction from mouse liver and Madin-Darby canine kidney cells
16. Molecular characterization and tissue distribution of ZO-2, a tight junction protein homologous to ZO-1 and the Drosophila discs-large tumor suppressor protein
17. ZO-3, a novel member of the MAGUK protein family found at the tight junction, interacts with ZO-1 and occludin
18. Molecular environment of ZO-1 in epithelial and non-epithelial cells
19. Direct binding of three tight junction-associated MAGUKs, ZO-1, ZO-2, and ZO-3, with the COOH termini of claudins
20. The tight junction protein ZO-1 establishes a link between the transmembrane protein occludin and the actin cytoskeleton
21. Molecular structure and assembly of the tight junction
22. Epidemiology of Pseudomonas aeruginosa keratitis in contact lens wearers
23. Pharmacokinetic considerations in the treatment of bacterial keratitis
24. The relative risk of ulcerative keratitis among users of daily-wear and extended-wear soft contact lenses: A case-control study
25. Signal transduction pathways involved in enterohemorrhagic Escherichia coli-induced alterations in T84 epithelial permeability
26. Helicobacter pylori disrupts epithelial barrier function in a process inhibited by protein kinase C activators
27. Pseudomonas aeruginosa and epithelial permeability: Role of virulence factors elastase and exotoxin A
28. Immortalized human corneal epithelial cells for ocular toxicity and inflammation studies
29. Human corneal epithelial primary cultures and cell lines with extended life span. In vitro model for ocular studies
30. An SV40-immortalized human corneal epithelial cell line and its characterization
31. Truncation mutants of the tight junction protein ZO-1 disrupt corneal epithelial cell morphology
32. Claudin-1 and -2: Novel integral membrane proteins localizing at tight junctions with no sequence similarity to occludin
33. Paracellin-1, a renal tight junction protein required for paracellular Mg2+ resorption
34. Claudin-11/OSP-based tight junctions of myelin sheaths in brain and Sertoli cells in testis
35. Phosphorylation of occludin correlates with occludin localization and function at the tight junction
36. CNS myelin and sertoli cell tight junction strands are absent in Osp/claudin-11 null mice
37. Pseudomonas aeruginosa lipopolysaccharides and pathogenesis
38. Modulation of barrier function of small intestinal epithelial cells by lamina propria fibroblasts in response to lipopolysaccharide: Possible role in TNFalpha in inducing barrier dysfunction
39. Corneal ulcers caused by protease and elastase from Pseudomonas aeruginosa
40. Pseudomonas keratitis: The role of an uncharacterized exoprotein, protease IV, in corneal virulence
41. Effect of Pseudomonas aeruginosa elastase, alkaline protease, and exotoxin A on corneal proteinases and proteins
42. Pili and lipopolysaccharide of Pseudomonas aeruginosa bind to the glycolipid asialo GM1
43. A bacterial protease perturbs the paracellular barrier function of transporting epithelial monolayers in culture
44. Defective LPS signaling in C3H/HeJ and C57BL/10ScCr mice: Mutations in Tlr4 gene
45. A family of human receptors structurally related to Drosophila Toll
46. Toll-like receptor-2 mediates lipopolysaccharide-induced cellular signalling
47. Toll, a new piece in the puzzle of innate immunity
48. Early cytokine and chemokine gene expression during Pseudomonas aeruginosa corneal infection in mice
49. Ocular surface epithelia express mRNA for human beta defensin-2
50. Mucin-like glycoprotein secretion is mediated by cyclic-AMP and protein kinase C signal transduction pathways in rat corneal epithelium
51. Transcriptional activation of mucin by Pseudomonas aeruginosa lipopolysaccharide in the pathogenesis of cystic fibrosis lung disease
52. Activation of NF-kappaB via a Src-dependent Ras-MAPK-pp90rsk pathway is required for Pseudomonas aeruginosa-induced mucin overproduction in epithelial cells
53. Cytokine-induced intestinal epithelial hyperpermeability: Role of nitric oxide
54. Transforming growth factor-beta1 preserves epithelial barrier function: Identification of receptors, biochemical intermediates, and cytokine antagonists
55. Unique role of allergens and the epithelium in asthma
56. Interferon-gamma decreases barrier function in T84 cells by reducing ZO-1 levels and disrupting apical actin
57. Loss of the tight junction MAGUK ZO-1 in breast cancer: Relationship to glandular differentiation and loss of heterozygosity