Angiogenesis is associated with vascular endothelial growth factor expression in cervical intraepithelial neoplasia

British Journal of Cancer

Volumn 76, Issue 11, 1997, Pages 1410-1415

  Dobbs, S P ^a   Hewett, P W ^a   Johnson, I R ^a   Carmichael, J ^a   Murray, J C ^a  

^a NOTTINGHAM CITY HOSPITAL   (United Kingdom)

Author keywords

Cervix; Dyskaryosis; Vascular endothelial growth factor; Vasculature

Indexed keywords

VASCULOTROPIN;

ANGIOGENESIS; ARTICLE; CONTROLLED STUDY; FEMALE; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MAJOR CLINICAL STUDY; PRIORITY JOURNAL; PROGNOSIS; TUMOR VASCULARIZATION; UTERINE CERVIX CARCINOMA IN SITU;

EID: 0030777860     PISSN: 00070920     EISSN: None     Source Type: Journal    
DOI: 10.1038/bjc.1997.571     Document Type: Article

References (45)

1. Abulafia O, Triest WE and Sherer DM (1996) Angiogenesis in squamous cell carcinoma in situ and microinvasive carcinoma of the uterine cervix. Obstet Gynecol 88: 927-932
2. Axelsson K, Ljung BM, Moore DH, Thor AD, Chew KL and Edgerton SM (1995) Tumour angiogenesis as a prognostic assay for invasive ductal breast carcinoma. J Natl Cancer Inst 87: 997-1008
3. Boocock CA, Charnock-Jones DS, Sharkey AM, McClaren J, Barker PJ, Wright KA, Twentyman PR and Smith SK (1995) Expression of vascular endothelial growth factor and its receptors flt and KDR in ovarian carcinoma. J Natl Cancer Inst 87: 506-516
4. Bossi P, Viale G, Lee AKC, Alfano RM, Coggi G and Bosari S (1995) Angiogenesis in colorectal tumours: microvessel quantitation in adenomas and carcinomas with clinicopathological correlations. Cancer Res 55: 5049-5033
5. Breier G, Albrecht U, Sterrer S and Risau W (1992) Expression of vascular endothelial growth factor during embryonic angiogenesis and endothelial cell differentiation. Development 114: 521-532
6. Brown LF, Berse B, Jackman RW, Tognazzi K, Manseau EJ, Senger DR and Dvorak HF (1993) Expression of vascular permeability factor (vascular endothelial growth factor) and its receptors in adenocarcinomas of the gastrointestinal tract. Cancer Res 53: 4727-4735
7. Brown LF, Berse B, Jackman RW, Tognazzi K, Guidi AJ, Dvorak HF, Senger DR, Connolly JL and Schnitt S (1995) Expression of vascular permeability factor (vascular endothelial growth factor) and its receptors in breast cancer. Hum Pathol 26: 86-91
8. Charnock-Jones D, Sharkey A, Rajput-Williams J, Burch D, Schofield J, Fountain S, Boocock C and Smith SK (1993) Identification and localisation of alternately spliced mRNAs for vascular endothelial growth factor in human uterus and estrogen regulation in endometrial carcinoma cell lines. Biol Reprod 48: 1120-1128
9. Folkman J (1990) What is the evidence that tumours are angiogenesis dependent? J Natl Cancer Inst 82: 4-6
10. Folkman J, Watson K, Ingber D and Hanahan D (1989) Induction of angiogenesis during the transition from hyperplasia to neoplasia. Nature 362: 841-844
11. Frank S, Hubner G, Breier G, Longaker MT, Greenhalgh DG and Werner S (1995) Regulation of vascular endothelial growth factor expression in cultured keratinocytes. Implications for normal and impaired wound healing. J Biol Chem 270: 12607-12613
12. Guidi AJ, Fischer L, Harris JR and Schnitt SJ (1994) Microvessel density and distribution in ductal carcinoma in situ of the breast. J Natl Cancer Inst 86: 614-619
13. Guidi AJ, Abu-Jawdeh G, Berse B, Jackman RW, Tognazzi K, Dvorak HF and Brown LF (1995) Vascular permeability factor (vascular endothelial growth factor) expression and angiogenesis in cervical neoplasia. J Natl Cancer Inst 87: 1237-1245
14. Horak ER, Leek R, Klenk N, LeJeune S, Smith K, Stuart N, Greenall M, Stepniewska K and Harris AL (1992) Angiogenesis, assessed by platelet/endothelial cell adhesion molecule antibodies, as indicator of node metastases and survival in breast cancer. Lancet 340: 1120-1123
15. Huibregtse JM, Scheffner M and Howley PM (1993) Cloning and expression of the cDNA for E6-AP, a protein that mediates the interaction of the human papillomavirus E6 oncoprotein with p53. Mol Cell Biol 13: 775-784
16. Kieser A, Weich HA, Brandner G, Marme D and Kolch W (1994) Mutant p53 potentiates protein kinase C induction of vascular endothelial growth factor expression. Oncogene 9: 963-969
17. Kim KJ, Li B, Winer J, Armanini M, Gillett N, Phillips HS and Ferrara N (1993) Inhibition of vascular endothelial growth factor-induced angiogenesis suppresses tumour growth in vivo. Nature 362: 841-844
18. Kohno Y, Iwanari O and Kitao M (1993) Importance of histological vascular density in cervical cancer treated with hypertensive intraarterial chemotherapy. Cancer 72: 2394-2400
19. Lehtinen M, Dillner J, Knekt P, Luostarinen T, Aromaa A, Kirnbauer R, Koskela P, Paavonen J, Peto R, Schiller JT and Hakama M (1996) Serologically diagnosed infection with human papilloma type 16 and risk for subsequent development of cervical carcinoma: nested case-control study. Br Med J 312: 537-539
20. Mclndoe WA, McClean MR, Jones RW and Mullins PR (1984) The invasive potential of carcinoma in situ of the cervix. Obstet Gynecol 64: 451-458
21. Millauer B, Shawver LK, Plate KH, Risau W and Ullrich A (1994) Glioblastoma growth inhibited in vivo by a dominant-negative FLK-1 mutant. Nature 367: 576-579
22. Mukhopadhay D, Tsiokas L and Sukhatme VP (1995) Wild-type p53 and v-src exert opposing influences on human vascular endothelial growth factor gene expression. Cancer Res 55: 6161-6165
23. Mustonen T and Alitalo K (1995) Endothelial receptor tyrosine kinases involved in angiogenesis. J Cell Biol 129: 895-898
24. Olivarez D, Ulbright T, DeRiese W, Foster R, Reister T, Einhorn L and Sedge G (1994) Neovascularization in clinical stage A testicular germ cell tumour: prediction of metastatic disease. Cancer Res 54: 2800-2802
25. Plate KH, Breier G, Weich HA and Risau W (1992) Vascular endothelial growth factor is a potential tumour angiogenesis factor in human gliomas in vivo. Nature 359: 845-847
26. Plate KH, Breier G and Risau W (1994a) Molecular mechanisms of developmental and tumour angiogenesis. Brain Pathol 4: 207-218
27. Plate KH, Breier G, Weich HA, Mennel HD and Risau W (1994b) Vascular endothelial growth factor and glioma angiogenesis: coordinate induction of VEGF receptors, distribution of VEGF protein and possible in vivo regulatory mechanisms. Int J Cancer 59: 520-529
28. Robertson JH, Woodend BE, Crozier EH and Hutchinson J (1988) Risk of cervical cancer associated with mild dyskaryosis. Br Med J 297: 18-21
29. Rockwell P and Goldstein N (1995) Anti-tumour effects of a neutralizing monoclonal antibody to the tyrosine kinase receptor FLK-1 (abstract). Proc Am Assoc Cancer Res 36: 425
30. Rutgers JL. Mattox TF and Vargas MP (1995) Angiogenesis in uterine cervical squamous cell carcinoma. Int J Gynecol Pathol 14: 114-118
31. Schienger K, Hockel M, Mitze M, Schaffer U, Weikel W, Knapstein PG and Lambert A (1995) Tumour vascularity - A novel prognostic factor in advanced cervical carcinoma. Gynecol Oncol 59: 57-66
32. Shafi MI (1994) The management of women with mild dyskaryosis. Cytological surveillance avoids over-treatment. Br Med J 309: 590-591
33. Sillman F, Boyce J and Fruchter R (1981) The significance of atypical vessels and neovascularization in cervical neoplasia. Am J Obstet Gynecol 139: 154-159
34. Siracka E, Siracky J and Pappova N (1994) Vascularization and radiocurability in cancer of the uterine cervix. A retrospective study. Neoplasma 29: 183-188
35. Smith-McCune KK and Weidner N (1994) Demonstration and characterization of the angiogenic properties of cervical dysplasia. Cancer Res 54: 800-804
36. Srivastava A, Laidler P, Davies R, Horgan K and Hughes LE (1988) The prognostic significance of tumour vascularity in intermediate thickness (0.76-4.0 mm) melanoma. A quantitative histologic study. Am J Pathol 133: 419-423
37. Stafl A and Mattingly RF (1975) Angiogenesis of cervical neoplasia. Am J Obstet Gynecol 121: 845-851
38. Thomas KA (1996) Vascular endothelial growth factor, a potent and selective angiogenic agent. J Biol Chem 271: 603-606
39. Toi M, Kashitani J and Tominaga T (1993) Tumour angiogenesis is an independent prognostic indicator in primary breast carcinoma. Int J Cancer 55: 371-374
40. Weidner N, Semple JP, Welch WR and Folkman J (1991) Tumour angiogenesis and metastasis - correlation in invasive breast carcinoma. N Engl J Med 324: 1-8
41. Weidner N, Folkman J, Pozza F, Bevilacqua P, Allred EN, Moore DH, Meli S and Gasparini G (1992) Tumour angiogenesis: a new significant and independent prognostic indicator in early stage breast carcinoma. J Natl Cancer Inst 84: 1875-1887
42. Weidner N, Carroll PR, Flax J, Blumenfeld W and Folkman J (1993) Tumour angiogenesis correlates with metastasis in invasive prostate carcinoma. Am J Pathol 143: 401-409
43. Wiggins DL, Granai CO, Steinhoff MM and Calabresi P (1995) Tumour angiogenesis as a prognostic factor in cervical carcinoma. Gynecol Oncol 56: 353-356
44. Wizigmann-Voos S, Breier G, Risau W and Plate KH (1995) Up-regulation of VEGF and its receptors in von Hippel-Lindau disease-associated and sporadic hemangioblastomas. Cancer Res 55: 1358-1364
45. Woodman CBJ, Rollason T, Ellis J, Tierney R, Wilson S and Young L (1996) Human papilloma virus infection and risk of epithelial abnormalities of the cervix. Br J Cancer 73: 553-556