Rapid detection of the C3435T polymorphism of multidrug resistance gene 1 using fluorogenic hybridization probes

Clinical Chemistry

Volumn 46, Issue 12, 2000, Pages 1995-1997

  Nauck, M ^a   Stein, U ^a   Von Karger, S ^a   Marz, W ^a   Wieland, H ^a  

^a UNIVERSITY OF FREIBURG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

DNA; DNA MARKER;

ARTICLE; DNA DETERMINATION; DNA HYBRIDIZATION; DNA POLYMORPHISM; DNA PROBE; GENETIC POLYMORPHISM; GENOTYPE; HUMAN; MULTIDRUG RESISTANCE;

EID: 0033636621     PISSN: 00099147     EISSN: None     Source Type: Journal    
DOI: 10.1093/clinchem/46.12.1995     Document Type: Article

References (14)

1. Pharmacogenomics: Translating functional genomics into rational therapeutics
2. Pharmacogenetics: A laboratory tool for optimizing therapeutic efficiency
3. Biochemical, cellular, and pharmacological aspects of the multidrug transporter
4. P-Glycoprotein and multidrug resistance
5. Pharmacological insights from P-glycoprotein knockout mice
6. Functional polymorphisms of the human multidrug-resistance gene: Multiple sequence variations and correlation of one allele with P-glycoprotein expression and activity in vivo
7. The lightcycler: A microvolume multisample fluorimeter with rapid temperature control
8. Rapid β-globin genotyping by multiplexing probe melting temperature and color
9. Application of a thermodynamic nearest-neighbor model to estimate nucleic acid stability and optimize probe design: Prediction of melting points of multiple mutations of apolipoprotein B-3500 and factor V with a hybridization probe genotyping assay on the lightcycler
10. Rapid genotyping of human platelet antigen 1 (HPA-1) with fluorophore-labelled hybridization probes on the lightcycler
11. Homogeneous amplification and variant detection by fluorescent hybridization probes
12. Genomic organization of the human multidrug resistance (MDR1) gene and origin of P-glycoproteins
13. 1-antitrypsin deficiency alleles Pi(*)Z and Pi(*)S by real-time fluorescence PCR and melting curves
14. Rapid genotyping of hemochromatosis gene mutations on the lightcycler with fluorescent hybridization probes