Evidence for apical endocytosis in polarized hepatic cells: Phosphoinositide 3-kinase inhibitors lead to the lysosomal accumulation of resident apical plasma membrane proteins

Journal of Cell Biology

Volumn 145, Issue 5, 1999, Pages 1089-1102

  Tuma, Pamela L ^a   Finnegan, Catherine M ^a   Yi, Ji Hyun ^a   Hubbard, Ann L ^a  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Endocytosis; Hepatocyte; Phosphoinositide 3 kinase; Polarity; Subapical compartment

Indexed keywords

2 MORPHOLINO 8 PHENYLCHROMONE; 5' NUCLEOTIDASE; CELL MEMBRANE PROTEIN; ENZYME INHIBITOR; MICROSOMAL AMINOPEPTIDASE; PHOSPHATIDYLINOSITOL 3 KINASE; WORTMANNIN;

ANIMAL CELL; APICAL MEMBRANE; ARTICLE; BASOLATERAL MEMBRANE; CELL COMPARTMENTALIZATION; CELL POLARITY; CELL ULTRASTRUCTURE; CELL VACUOLE; CONTROLLED STUDY; CYTOARCHITECTURE; ENDOCYTOSIS; ENDOSOME; INTERNALIZATION; LIVER CELL; LYSOSOME; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN LOCALIZATION; RAT; TRANSCYTOSIS;

ANIMALIA;

EID: 0033620611     PISSN: 00219525     EISSN: None     Source Type: Journal    
DOI: 10.1083/jcb.145.5.1089     Document Type: Article

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