Structural analysis of mutant hen egg-white lysozyme preferring a minor binding mode

Biochimica et Biophysica Acta - Protein Structure and Molecular Enzymology

Volumn 1384, Issue 1, 1998, Pages 23-31

  Maenaka, Katsumi ^a,b,f   Matsushima, Masaaki ^c,d   Kawai, Gota ^b   Watanabe, Kimitsuna ^b   Kuroki, Ryota ^e   Kumagai, Izumi ^a  

^a TOHOKU UNIVERSITY   (Japan)

^b UNIVERSITY OF TOKYO   (Japan)

^c BIOMOL ENG RESEARCH INSTITUTE   (Japan)

^d Rational Drug Design Laboratories   (Japan)

^e Ctrl Labs for Key Technology   (Japan)

^f UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

Hen egg white lysozyme; Protein carbohydrate interaction; Site directed mutagenesis; Substrate binding mode; X ray crystallography

Indexed keywords

CARBOHYDRATE; EGG WHITE; LYSOZYME; MUTANT PROTEIN;

AMINO ACID SUBSTITUTION; ARTICLE; ENZYME ACTIVITY; ENZYME BINDING; ENZYME STRUCTURE; GENETIC ENGINEERING; HYDROGEN BOND; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PRIORITY JOURNAL; SACCHAROMYCES CEREVISIAE; SITE DIRECTED MUTAGENESIS; X RAY CRYSTALLOGRAPHY;

ANIMALS; BINDING SITES; CARBOHYDRATE METABOLISM; CHICKENS; CRYSTALLOGRAPHY, X-RAY; EGG WHITE; MURAMIDASE; MUTATION; PROTEIN BINDING; PROTEIN CONFORMATION; SUBSTRATE SPECIFICITY;

SACCHAROMYCES CEREVISIAE;

EID: 0032560055     PISSN: 01674838     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0167-4838(97)00199-4     Document Type: Article

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