The anti-proliferative effect of sulindac and sulindac sulfide on HT-29 colon cancer cells: Alterations in tumor suppressor and cell cycle-regulatory proteins

Oncogene

Volumn 12, Issue 4, 1996, Pages 893-901

  Goldberg, Yael ^a   Nassif, Imad I ^a   Pittas, Anastassios ^b   Tsai, Li Lan ^a   Dynlacht, Brian D ^c   Rigas, Basil ^a,b   Shiff, Steven J ^a,b  

^a ROCKEFELLER UNIVERSITY   (United States)

^b WEILL CORNELL MEDICAL COLLEGE   (United States)

^c HARVARD UNIVERSITY   (United States)

Author keywords

Colon cancer; Cyclin dependent kinases; Cyclins; NSAIDs; p21(WAF 1); Tumor suppressor proteins

Indexed keywords

ANTINEOPLASTIC AGENT; CELL CYCLE PROTEIN; CYCLIN DEPENDENT KINASE; CYCLINE; ENZYME INHIBITOR; MUTANT PROTEIN; NONSTEROID ANTIINFLAMMATORY AGENT; PROTEIN P53; RETINOBLASTOMA PROTEIN; SULINDAC; SULINDAC SULFIDE;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CELL CULTURE; COLON CANCER; CONTROLLED STUDY; DRUG EFFECT; HUMAN; HUMAN CELL; MITOSIS INHIBITION; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; PROTEIN SYNTHESIS REGULATION; TUMOR SUPPRESSOR GENE;

ADENOCARCINOMA; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; ANTINEOPLASTIC AGENTS; APOPTOSIS; BLOTTING, WESTERN; CELL CYCLE; CELL DIVISION; CELL LINE; COLONIC NEOPLASMS; CYCLINS; GENES, P53; GENES, RETINOBLASTOMA; HUMANS; MITOSIS; RETINOBLASTOMA PROTEIN; SULINDAC; TUMOR SUPPRESSOR PROTEIN P53;

EID: 0030044422     PISSN: 09509232     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (62)

1. Chen Y, Chen P-L and Lee W-H. (1994). Mol. Cell. Biol., 14, 6764-6772.
2. Chin K-V, Ueda K, Pastan I and Gottesman MM. (1992). Science, 255, 459-462.
3. Clarke AR, Gledhill S, Hooper ML, Bird CC and Wyllie AH. (1994). Oncogene, 9, 1767-1773.
4. Dittmer D, Pati S, Zambetti G, Chu S, Teresky AK, Moore M, Finlay C and Levine AJ. (1993). Nature Gen., 4, 42-45.
5. Duggan DE, Hooke KF and Hwang SS. (1980). Drug Metab. Dispos., 8, 241-246.
6. El-Deiry WS, Harper JW, O'Connor PM, Velculescu VE, Canman CE, Jackman J, Pietenpol JA, Burrell M, Hill DE, Wang Y, Wiman KG, Mercer WE, Kastan MB, Kohn KW, Elledge SJ, Kanzler KW and Vogelstein B. (1994). Cancer Res., 54, 1169-1174.
7. El-Deiry WS, Tokino T, Velculescu VE, Levy DB, Parsons R, Trent JM, Lin D, Mercer WE, Kinzler KW and Vogelstein B. (1993). Cell, 75, 817-825.
8. Faha B, Ewen ME, Tsai LH, Livingston DM and Harlow E. (1992). Science, 255, 87-90.
9. Flores-Rozas H, Kelman Z, Dean FB, Pan Z-Q, Harper JW, Elledge SJ, O'Donnell M and Hurwitz J. (1994). Proc. Natl. Acad. Sci. USA, 91, 8655-8659.
10. Fritsche M, Haessler C and Brandner G. (1993). Oncogene, 8, 307-318.
11. Giardiello FM, Hamilton SR, Krush AJ, Piantadosi S, Hylind LM, Celano P, Booker SV, Robinson CR and Offerhaus GJ. (1993). New Engl. J. Med., 328, 1313-1316.
12. Gope R and Gope ML. (1992). Mol. Cell. Biochem., 110, 123-133.
13. Gope R and Gope ML. (1993). Cell. Molec. Biol., 39, 589-597.
14. Haas-Kogan DA, Kogan SC, Levi D, Dazin P, T'Ang A, Fung Y-KT and Israel MA. (1995). EMBO J., 14, 461-472.
15. Halevy O, Michalovitz D and Oren M. (1990). Science, 250, 113-116.
16. Halevy O, Novitch BG, Spicer DB, Skapek SX, Rhee J, Hannon GJ, Beach D and Lassar AB. (1995). Science, 267, 1018-1021.
17. Hanif R, Pittas A, Feng Y, Koutsos MI, Staiano-Coico L, Shiff SJ and Rigas B. (1995). Gastroenterology, 108, A478.
18. Harper JW, Adami GR, Wei N, Keyomarsi K and Elledge SJ. (1993). Cell, 75, 805-816.
19. Harper JW, Elledge SJ, Keyomarsi K, Dynlacht B, Tsai L-H, Zhang P, Dowbrowolski S, Bai C, Connell-Crowley L, Swindell E, Fox MP and Wei N. (1995). Mol. Biol. Cell, 6, 387-400.
20. Harvey M, Vogel H, Morris D, Bradley A, Bernstein A and Donehower LA. (1995). Nature Gen., 9, 305-311.
21. Herz F, Schermer A, Halwer M and Bogart LH. (1981). Arch. Biochem. Biophys., 210, 581-591.
22. Hinds PW, Finlay CA, Quartin RS, Baker SJ, Fearon ER, Vogelstein B and Levine AJ. (1990). Cell Growth Diff., 1, 571-580.
23. Hollstein M, Sidransky D, Vogelstein B and Harris CC. (1991). Science, 253, 49-53.
24. Hu QJ, Bautista C, Edwards GM, Defeo-Jones D, Jones RE and Harlow E. (1991). Mol. Cell. Biol., 11, 5792-5799.
25. Insel P. (1990). Goodman and Gilman's The Pharmacological Basis of Therapeutics. Gilman AG, Rail TW, Nies AS and Taylor P (eds). Pergamon Press: New York, pp. 638-681.
26. Jiang H, Lin J, Su Z-Z, Collart FR, Huberman E and Fisher PB. (1994). Oncogene, 9, 3397-3406.
27. Jiang H, Lin J, Su Z-Z, Herlyn M, Kerbel RS, Weissman BE, Welch DR and Fisher PB. (1995). Oncogene, 10, 1855-1864.
28. Kastan MB, Onyekwere O, Sidransky D, Vogelstein B and Craig RW. (1991). Cancer Res., 51, 6304-6311.
29. Kim YS, Tsao D, Siddiqui B, Whitehead JS, Arnstein P, Bennett J and Hicks J. (1980). Cancer, 45, 1185-1192.
30. Levine AJ, Perry ME, Chang A, Silver A, Dittmer D, Wu M and Welsh D. (1994). Br. J. Cancer, 69, 409-416.
31. Lowe SW, Bodis S, McClatchey A, Remington L, Ruley HE, Fisher DE, Housman DE and Jacks T. (1994). Science, 266, 807-810.
32. Macleod KF, Sherry N, Hannon G, Beach D, Tokino T, Kinzler K, Vogelstein B and Jacks T. (1995). Genes Develop., 9, 935-944.
33. Maity A, McKenna WG and Muschel RJ. (1994). Radiother. Oncol., 31, 1-13.
34. Michalovitz D, Halevy O and Oren M. (1990). Cell, 62, 671-680.
35. Morgan DO. (1995). Nature, 374, 131-134.
36. Nakanishi M, Robetorye RS, Adami GR, Pereira-Smith OM and Smith JR. (1995). EMBO J., 14, 555-563.
37. Nigro JM, Baker SJ, Preisinger AC, Jessup JM, Hostetter R, Cleary K, Bigner SH, Davidson N, Baylin S, Devilee P, Glover T, Collins FS, Weston A, Modali R, Harris CC and Vogelstein B. (1989). Nature, 342, 705-708.
38. Paganini-Hill A. (1994). Sem. Surg. Oncol., 10, 158-164.
39. Parker SB, Eichele G, Zhang P, Rawls A, Sands AT, Bradley A, Olson EN, Harper JW and Elledge SJ. (1995). Science, 267, 1024-1027.
40. Piazza GA, Rahm ALK, Krutzsch M, Sperl G, Paranka NS, Gross PH, Brendel K, Burt RW, Alberts DS, Pamukcu R and Ahnen DJ. (1995). Cancer Res., 55, 3110-3116.
41. Rao CV, Rivenson R, Simi B, Zang E, Kelloff G, Steele V and Reddy BS. (1995). Cancer Res., 55, 1464-1472.
42. Razvi ES and Welch RM. (1995). Adv. Virus Res., 45, 1-60.
43. Rigas B, Goldman IS and Levine L. (1993). J. Lab. Clin. Med., 122, 518-523.
44. Rodrigues NR, Rowan A, Smith ME, Kerr IB, Bodmer WF, Gannon JV and Lane DP. (1990). Proc. Natl. Acad. Sci. USA, 87, 7555-7559.
45. Schroy PC, Rustgi AK, Ikonomu E, Liu XP, Polito J, Andry C and O'Keane JC. (1994). J. Cell. Physiol., 161, 111-123.
46. Schwaller J, Koeffler HP, Niklaus G, Loetscher P, Nagel S, Fey MF and Tobler A. (1995). J. Clin. Invest., 95, 973-979.
47. Shaw P, Bovey R, Tardy S, Sahli R, Sordat B and Costa J. (1992). Proc. Natl. Acad. Sci. USA, 89, 4495-4499.
48. Sheikh MS, Li X-S, Chen J-C, Shao Z-M, Ordonez JV and Fontana JA. (1994). Oncogene, 9, 3407-3415.
49. Sherr CJ. (1993). Cell, 73, 1059-1065.
50. Sherr CJ. (1994). Cell, 79, 551-555.
51. Shiff SJ, Koutsos MI, Qiao L and Rigas B. (1996). Exp. Cell Res., 222.
52. Shiff SJ, Qiao L, Tsai L-L and Rigas B. (1995). J. Clin. Invest., 96, 491-503.
53. Steinman RA, Hoffman B, Iro A, Guillouf C, Liebermann DA and El-Houseini ME. (1994). Oncogene, 9, 3389-3396.
54. Tsai L-H, Lees E, Faha B, Harlow E and Riabowol K. (1993). Oncogene, 8, 1593-1602.
55. Turner D and Berkel HJ. (1993). Can. Med. Assoc. J., 149, 595-602.
56. Waddell WR, Gerner RE and Reich MP. (1983). J. Surg. Oncol., 22, 197-211.
57. Waddell WR and Loughry RW. (1983). J. Surg. Oncol., 24, 83-87.
58. Waga S, Hannon GJ, Beach D and Stillman B. (1994). Nature, 369, 574-578.
59. Weinberg RA. (1995). Cell, 81, 323-330.
60. Xiong Y, Hannon GJ, Zhang H, Casso D, Kobayashi R and Beach D. (1993a). Nature, 366, 701-704.
61. Xiong Y, Zhang H and Beach D. (1993b). Genes Develop., 7, 1572-1583.
62. Zhang W, Grasso L, McClain CD, Gambel AM, Cha Y, Travali S, Deisseroth AB and Mercer WE. (1995). Cancer Res., 55, 668-614.