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Volumn 211, Issue 2, 1999, Pages 255-267

The transcription factor MEF2C-null mouse exhibits complex vascular malformations and reduced cardiac expression of angiopoietin 1 and VEGF

Author keywords

Angiopoietin 1; Cardiovascular development; MEF2; VEGF

Indexed keywords

ANGIOPOIETIN 1; CYTOKINE; MESSENGER RNA; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR MEF2C; UNCLASSIFIED DRUG; VASCULOTROPIN;

EID: 0033566045     PISSN: 00121606     EISSN: None     Source Type: Journal    
DOI: 10.1006/dbio.1999.9307     Document Type: Article
Times cited : (165)

References (53)
  • 1
    • 0031905861 scopus 로고    scopus 로고
    • Vascular endothelial growth factor D (VEGF-D) is a ligand for the tyrosine kinases VEGF receptor 2 (Flk1) and VEGF receptor 3 (Flt4)
    • Achen M. G., Jeltsch M., Kukk E., Makinen T., Vitali A., Wilks A. F., Alitalo K., Stacker S. A. Vascular endothelial growth factor D (VEGF-D) is a ligand for the tyrosine kinases VEGF receptor 2 (Flk1) and VEGF receptor 3 (Flt4). Proc. Natl. Acad. Sci. USA. 95:1998;548-553.
    • (1998) Proc. Natl. Acad. Sci. USA , vol.95 , pp. 548-553
    • Achen, M.G.1    Jeltsch, M.2    Kukk, E.3    Makinen, T.4    Vitali, A.5    Wilks, A.F.6    Alitalo, K.7    Stacker, S.A.8
  • 2
    • 0030806273 scopus 로고    scopus 로고
    • Conditional switching of vascular endothelial growth factor (VEGF) expression in tumors: Induction of endothelial cell shedding and regression of hemangioblastoma-like vessels by VEGF withdrawal
    • Benjamin L. E., Keshet E. Conditional switching of vascular endothelial growth factor (VEGF) expression in tumors: Induction of endothelial cell shedding and regression of hemangioblastoma-like vessels by VEGF withdrawal. Proc. Natl. Acad. Sci. USA. 94:1997;8761-8766.
    • (1997) Proc. Natl. Acad. Sci. USA , vol.94 , pp. 8761-8766
    • Benjamin, L.E.1    Keshet, E.2
  • 7
    • 0030955863 scopus 로고    scopus 로고
    • 5-HT2B receptor-mediated serotonin morphogenetic functions in mouse cranial neural crest and myocardial cells
    • Choi D.-S., Ward S. J., Messaddeq N., Launay J.-M., Maroteaux L. 5-HT2B receptor-mediated serotonin morphogenetic functions in mouse cranial neural crest and myocardial cells. Development. 124:1997;1745-1755.
    • (1997) Development , vol.124 , pp. 1745-1755
    • Choi, D.-S.1    Ward, S.J.2    Messaddeq, N.3    Launay, J.-M.4    Maroteaux, L.5
  • 9
    • 0030008312 scopus 로고    scopus 로고
    • Role of the thrombin receptor in development and evidence for a second receptor
    • Connolly A. J., Ishihara H., Kahn M. L., Farese R. V., Coughlin S. R. Role of the thrombin receptor in development and evidence for a second receptor. Nature. 381:1996;516-519.
    • (1996) Nature , vol.381 , pp. 516-519
    • Connolly, A.J.1    Ishihara, H.2    Kahn, M.L.3    Farese, R.V.4    Coughlin, S.R.5
  • 10
    • 0029074681 scopus 로고
    • Defective haematopoiesis and vasculogenesis in transforming growth factor-β1 knock out mice
    • Dickson M. C., Martin J. S., Cousins F. M., Kulkarni A. B., Karlsson S., Akhurst R. J. Defective haematopoiesis and vasculogenesis in transforming growth factor-β1 knock out mice. Development. 121:1995;1845-1854.
    • (1995) Development , vol.121 , pp. 1845-1854
    • Dickson, M.C.1    Martin, J.S.2    Cousins, F.M.3    Kulkarni, A.B.4    Karlsson, S.5    Akhurst, R.J.6
  • 11
    • 0029155806 scopus 로고
    • Exogenous vascular endothelial growth factor induces malformed and hyperfused vessels during embryonic neovascularization
    • Drake C. J., Little C. D. Exogenous vascular endothelial growth factor induces malformed and hyperfused vessels during embryonic neovascularization. Proc. Natl. Acad. Sci. USA. 92:1995;7657-7661.
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 7657-7661
    • Drake, C.J.1    Little, C.D.2
  • 12
    • 0031455913 scopus 로고    scopus 로고
    • TAL1/SCL is expressed in endothelial progenitor cells/angioblasts and defines a dorsal-to-ventral gradient of vasculogenesis
    • Drake C. J., Brandt S. J., Trusk T. C., Little C. D. TAL1/SCL is expressed in endothelial progenitor cells/angioblasts and defines a dorsal-to-ventral gradient of vasculogenesis. Dev. Biol. 192:1997;17-30.
    • (1997) Dev. Biol. , vol.192 , pp. 17-30
    • Drake, C.J.1    Brandt, S.J.2    Trusk, T.C.3    Little, C.D.4
  • 14
    • 0028122465 scopus 로고
    • Dominant-negative and targeted null mutations in the endothelial receptor tyrosine kinase, tek, reveal a critical role in vasculogenesis of the embryo
    • Dumont D. J., Gradwohl G., Fong G.-H., Puri M. C., Gertsenstein M., Auerbach A., Breitman M. L. Dominant-negative and targeted null mutations in the endothelial receptor tyrosine kinase, tek, reveal a critical role in vasculogenesis of the embryo. Genes Dev. 8:1994;1897-1909.
    • (1994) Genes Dev. , vol.8 , pp. 1897-1909
    • Dumont, D.J.1    Gradwohl, G.2    Fong, G.-H.3    Puri, M.C.4    Gertsenstein, M.5    Auerbach, A.6    Breitman, M.L.7
  • 15
    • 0030959941 scopus 로고    scopus 로고
    • Ligand-dependent development of the endothelial and hemapoietic lineages from embryonic mesodermal cells expressing vascular endothelial growth factor receptor 2
    • Eichmann A., Corbel C., Nataf V., Vaigot P., Breant C., Le Douarin N. M. Ligand-dependent development of the endothelial and hemapoietic lineages from embryonic mesodermal cells expressing vascular endothelial growth factor receptor 2. Proc. Natl. Acad. Sci. USA. 94:1997;5141-5146.
    • (1997) Proc. Natl. Acad. Sci. USA , vol.94 , pp. 5141-5146
    • Eichmann, A.1    Corbel, C.2    Nataf, V.3    Vaigot, P.4    Breant, C.5    Le Douarin, N.M.6
  • 16
    • 0028279115 scopus 로고
    • Mef2 gene expression marks the cardiac and skeletal muscle lineages during mouse embryogenesis
    • Edmondson D. G., Lyons G. E., Martin J. F., Olson E. N. Mef2 gene expression marks the cardiac and skeletal muscle lineages during mouse embryogenesis. Development. 120:1994;1251-1263.
    • (1994) Development , vol.120 , pp. 1251-1263
    • Edmondson, D.G.1    Lyons, G.E.2    Martin, J.F.3    Olson, E.N.4
  • 18
    • 0030049945 scopus 로고    scopus 로고
    • Myocyte enhancer binding factor-2 expression and activity in vascular smooth muscle cells: Association with the activated phenotype
    • Firulli A. B., Miano J. M., Bi W., Johnson A. D., Casscells W., Olson E. N., Schwarz J. J. Myocyte enhancer binding factor-2 expression and activity in vascular smooth muscle cells: Association with the activated phenotype. Circ. Res. 78:1996;196-204.
    • (1996) Circ. Res. , vol.78 , pp. 196-204
    • Firulli, A.B.1    Miano, J.M.2    Bi, W.3    Johnson, A.D.4    Casscells, W.5    Olson, E.N.6    Schwarz, J.J.7
  • 19
    • 0028825887 scopus 로고
    • Overexpression of vascular endothelial growth factor in the avian embryo induces hypervascularization and increased vascular permeability without alterations of embryonic pattern formation
    • Flamme I., von Reutern M., Drexler H. C. A., Syed-Ali S., Risau W. Overexpression of vascular endothelial growth factor in the avian embryo induces hypervascularization and increased vascular permeability without alterations of embryonic pattern formation. Dev. Biol. 171:1995;399-414.
    • (1995) Dev. Biol. , vol.171 , pp. 399-414
    • Flamme, I.1    Von Reutern, M.2    Drexler, H.C.A.3    Syed-Ali, S.4    Risau, W.5
  • 20
    • 0029021660 scopus 로고
    • Role of the Flt-1 receptor tyrosine kinase in regulating the assembly of vascular endothelium
    • Fong G.-H., Rossant J., Gertsenstein M., Breitman M. L. Role of the Flt-1 receptor tyrosine kinase in regulating the assembly of vascular endothelium. Nature. 376:1995;66-70.
    • (1995) Nature , vol.376 , pp. 66-70
    • Fong, G.-H.1    Rossant, J.2    Gertsenstein, M.3    Breitman, M.L.4
  • 21
    • 0013920833 scopus 로고
    • Spectrum of congenital cardiac anomalies produced in chick embryos by mechanical interference with cardiogenesis
    • Gessner I. H. Spectrum of congenital cardiac anomalies produced in chick embryos by mechanical interference with cardiogenesis. Circ. Res. 18:1966;625-632.
    • (1966) Circ. Res. , vol.18 , pp. 625-632
    • Gessner, I.H.1
  • 22
    • 0030894683 scopus 로고    scopus 로고
    • Activation of the transcription factor MEF2C by the MAP kinase p38 in inflammation
    • Han J., Jiang Y., Li Z., Kravchenko V. V., Ulevitch R. J. Activation of the transcription factor MEF2C by the MAP kinase p38 in inflammation. Nature. 386:1997;296-299.
    • (1997) Nature , vol.386 , pp. 296-299
    • Han, J.1    Jiang, Y.2    Li, Z.3    Kravchenko, V.V.4    Ulevitch, R.J.5
  • 24
    • 0030911999 scopus 로고    scopus 로고
    • Unilateral vitilline vein ligation alters intracardiac blood flow patterns and morphogenesis in the chick embryo
    • Hogers B., DeRuiter M. C., Gittenberger-de Groot A. C., Poelmann R. E. Unilateral vitilline vein ligation alters intracardiac blood flow patterns and morphogenesis in the chick embryo. Circ. Res. 80:1996;473-481.
    • (1996) Circ. Res. , vol.80 , pp. 473-481
    • Hogers, B.1    Deruiter, M.C.2    Gittenberger-De Groot, A.C.3    Poelmann, R.E.4
  • 26
    • 0030694387 scopus 로고    scopus 로고
    • BMK1/ERK5 regulates serum-induced early gene expression through transcription factor MEF2C
    • Kato Y., Kravchenko V. V., Tapping R. I., Han J., Ulevitch R. J., Lee J. D. BMK1/ERK5 regulates serum-induced early gene expression through transcription factor MEF2C. EMBO J. 16:1997;7054-7066.
    • (1997) EMBO J. , vol.16 , pp. 7054-7066
    • Kato, Y.1    Kravchenko, V.V.2    Tapping, R.I.3    Han, J.4    Ulevitch, R.J.5    Lee, J.D.6
  • 27
    • 0030453355 scopus 로고    scopus 로고
    • VEGF-C receptor binding and pattern of expression with VEGFR-3 suggests a role in lymphatic vascular development
    • Kull E., Lymboussaki A., Taira S., Kaipainen A., Jeltsch M., Joukov V., Alitalo K. VEGF-C receptor binding and pattern of expression with VEGFR-3 suggests a role in lymphatic vascular development. Development. 122:1996;3829-3837.
    • (1996) Development , vol.122 , pp. 3829-3837
    • Kull, E.1    Lymboussaki, A.2    Taira, S.3    Kaipainen, A.4    Jeltsch, M.5    Joukov, V.6    Alitalo, K.7
  • 28
    • 0028917564 scopus 로고
    • Requirement of MADS domain transcription factor d-MEF2 for muscle formation in Drosophila
    • Lilly B., Zhao B., Ranganayakulu G., Paterson B. M., Shulz R. A., Olson E. N. Requirement of MADS domain transcription factor d-MEF2 for muscle formation in Drosophila. Science. 267:1995;688-693.
    • (1995) Science , vol.267 , pp. 688-693
    • Lilly, B.1    Zhao, B.2    Ranganayakulu, G.3    Paterson, B.M.4    Shulz, R.A.5    Olson, E.N.6
  • 29
    • 0030911475 scopus 로고    scopus 로고
    • Control of cardiac morphogenesis and myogenesis by the myogenic transcription factor MEF2C
    • Lin Q., Schwarz J. J., Olson E. N. Control of cardiac morphogenesis and myogenesis by the myogenic transcription factor MEF2C. Science. 276:1997;1404-1407.
    • (1997) Science , vol.276 , pp. 1404-1407
    • Lin, Q.1    Schwarz, J.J.2    Olson, E.N.3
  • 31
    • 0030756325 scopus 로고    scopus 로고
    • Pericyte loss and microaneurysm formation in PDGF-B-deficient mice
    • Lindahl P., Johansson B. R., Leveen P., Betsholtz C. Pericyte loss and microaneurysm formation in PDGF-B-deficient mice. Science. 277:1997;242-245.
    • (1997) Science , vol.277 , pp. 242-245
    • Lindahl, P.1    Johansson, B.R.2    Leveen, P.3    Betsholtz, C.4
  • 32
    • 0029085629 scopus 로고
    • Expression of mef2 genes in the mouse central nervous system suggests a role in neuronal maturation
    • Lyons G. E., Micales B. K., Schwarz J., Martin J. F., Olson E. N. Expression of mef2 genes in the mouse central nervous system suggests a role in neuronal maturation. J. Neurosci. 15:1995;5727-5738.
    • (1995) J. Neurosci. , vol.15 , pp. 5727-5738
    • Lyons, G.E.1    Micales, B.K.2    Schwarz, J.3    Martin, J.F.4    Olson, E.N.5
  • 34
    • 0027243922 scopus 로고
    • Myocyte enhancer factor (mef) 2c: A tissue-restricted member of the mef-2 family of transcription factors
    • Martin J. F., Schwarz J. J., Olson E. N. Myocyte enhancer factor (mef) 2c: A tissue-restricted member of the mef-2 family of transcription factors. Proc. Natl. Acad. Sci. USA. 90:1993;5282-5286.
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 5282-5286
    • Martin, J.F.1    Schwarz, J.J.2    Olson, E.N.3
  • 36
    • 0031015426 scopus 로고    scopus 로고
    • Vascular system defects and impaired cell chemokinesis as a result of Gα13 deficiency
    • Offermanns S., Mancino V., Revel J. P., Simon M. I. Vascular system defects and impaired cell chemokinesis as a result of Gα13 deficiency. Science. 275:1997;533-536.
    • (1997) Science , vol.275 , pp. 533-536
    • Offermanns, S.1    Mancino, V.2    Revel, J.P.3    Simon, M.I.4
  • 38
    • 0028808913 scopus 로고
    • Regulation of muscle differentiation by the MEF2 family of MADS box transcription factors
    • Olson E. N., Perry M., Schulz R. A. Regulation of muscle differentiation by the MEF2 family of MADS box transcription factors. Dev. Biol. 172:1995;2-14.
    • (1995) Dev. Biol. , vol.172 , pp. 2-14
    • Olson, E.N.1    Perry, M.2    Schulz, R.A.3
  • 39
    • 0030952289 scopus 로고    scopus 로고
    • Mechanisms of angiogenesis
    • Risau W. Mechanisms of angiogenesis. Nature. 386:1997;671-674.
    • (1997) Nature , vol.386 , pp. 671-674
    • Risau, W.1
  • 41
    • 0032100732 scopus 로고    scopus 로고
    • HIF-1α is required for solid tumor formation and embryonic vascularization
    • Ryan H. E., Lo J., Johnson R. S. HIF-1α is required for solid tumor formation and embryonic vascularization. EMBO J. 17:1998;3005-3015.
    • (1998) EMBO J. , vol.17 , pp. 3005-3015
    • Ryan, H.E.1    Lo, J.2    Johnson, R.S.3
  • 43
    • 0028943808 scopus 로고
    • Vascular endothelial cell lineage-specific promoter in transgenic mice
    • Schlaeger T. M., Qin Y., Fujiwara Y., Magram J., Sato T. N. Vascular endothelial cell lineage-specific promoter in transgenic mice. Development. 121:1995;1089-1098.
    • (1995) Development , vol.121 , pp. 1089-1098
    • Schlaeger, T.M.1    Qin, Y.2    Fujiwara, Y.3    Magram, J.4    Sato, T.N.5
  • 45
    • 0032549799 scopus 로고    scopus 로고
    • Neuropilin-1 is expressed by endothelial and tumor cells as an isoform-specific receptor for vascular endothelial growth factor
    • Soker S., Takashima S., Miao H. Q., Neufeld G., Klagsbrun M. Neuropilin-1 is expressed by endothelial and tumor cells as an isoform-specific receptor for vascular endothelial growth factor. Cell. 92:1998;735-745.
    • (1998) Cell , vol.92 , pp. 735-745
    • Soker, S.1    Takashima, S.2    Miao, H.Q.3    Neufeld, G.4    Klagsbrun, M.5
  • 46
    • 0032215354 scopus 로고    scopus 로고
    • VEGF gene delivery to muscle: Potential role for vasculogenesis in adults
    • Springer M. L., Chen A. S., Kraft P. E., Bednarski M., Blau H. M. VEGF gene delivery to muscle: Potential role for vasculogenesis in adults. Mol. Cell. 2:1998;549-558.
    • (1998) Mol. Cell , vol.2 , pp. 549-558
    • Springer, M.L.1    Chen, A.S.2    Kraft, P.E.3    Bednarski, M.4    Blau, H.M.5
  • 48
    • 0028810741 scopus 로고    scopus 로고
    • Cloche, an early acting zebrafish gene, is required by both the endothelial and hematopoietic lineages
    • (195)
    • Stainier, D. Y. R., Weinstein, B. M., Detrich, H. W., Zon, L. I., and Fishman, M. C. (195). Cloche, an early acting zebrafish gene, is required by both the endothelial and hematopoietic lineages. Development121, 3141-3150.
    • Development , vol.121 , pp. 3141-3150
    • Stainier, D.Y.R.1    Weinstein, B.M.2    Detrich, H.W.3    Zon, L.I.4    Fishman, M.C.5
  • 50
    • 0345647074 scopus 로고    scopus 로고
    • Characterization of myocyte enhancer factor 2 (MEF2) expression in B and T cells: MEF2C is a B cell-restricted transcription factor in lymphocytes
    • Swanson B. J., Jack H. M., Lyons G. E. Characterization of myocyte enhancer factor 2 (MEF2) expression in B and T cells: MEF2C is a B cell-restricted transcription factor in lymphocytes. Mol. Immunol. 35:1998;445-458.
    • (1998) Mol. Immunol. , vol.35 , pp. 445-458
    • Swanson, B.J.1    Jack, H.M.2    Lyons, G.E.3
  • 51
    • 0031020884 scopus 로고    scopus 로고
    • Endothelial PAS domain protein 1 (EPAS1), a transcription factor selectively expressed in endothelial cells
    • Tian H., McKnight S. L., Russell D. W. Endothelial PAS domain protein 1 (EPAS1), a transcription factor selectively expressed in endothelial cells. Genes Dev. 11:1997;72-82.
    • (1997) Genes Dev. , vol.11 , pp. 72-82
    • Tian, H.1    McKnight, S.L.2    Russell, D.W.3
  • 52
    • 0032520080 scopus 로고    scopus 로고
    • Unsuspected role for the T-cell leukemia protein SCL/tal-1 in vascular development
    • Visvader J. E., Fujiwara Y., Orkin S. H. Unsuspected role for the T-cell leukemia protein SCL/tal-1 in vascular development. Genes Dev. 12:1998;473-479.
    • (1998) Genes Dev. , vol.12 , pp. 473-479
    • Visvader, J.E.1    Fujiwara, Y.2    Orkin, S.H.3
  • 53
    • 0032577446 scopus 로고    scopus 로고
    • Molecular distinction and angiogenic interaction between embryonic arteries and veins revealed by ephrin-B2 and its receptor Eph-B4
    • Wang H. U., Chen Z.-F., Anderson D. J. Molecular distinction and angiogenic interaction between embryonic arteries and veins revealed by ephrin-B2 and its receptor Eph-B4. Cell. 93:1998;741-753.
    • (1998) Cell , vol.93 , pp. 741-753
    • Wang, H.U.1    Chen, Z.-F.2    Anderson, D.J.3


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