-
1
-
-
0000795715
-
Introduction. Structure and metabolism of plasma lipoproteins
-
C. R. Scriver, A. L. Beaudet, W. S. Sly, and D. Valle, editors. McGraw-Hill, New York
-
Havel, R. J., and J. P. Kane. 1995. Introduction. Structure and metabolism of plasma lipoproteins. In The Metabolic and Molecular Bases of Inherited Disease. 7th edition. Vol. 2. C. R. Scriver, A. L. Beaudet, W. S. Sly, and D. Valle, editors. McGraw-Hill, New York. 1841-1851.
-
(1995)
The Metabolic and Molecular Bases of Inherited Disease. 7th Edition
, vol.2
, pp. 1841-1851
-
-
Havel, R.J.1
Kane, J.P.2
-
2
-
-
0025086368
-
Recent progress in understanding apolipoprotein B
-
Young, S. G. 1990. Recent progress in understanding apolipoprotein B. Circulation. 82: 1574-1594.
-
(1990)
Circulation
, vol.82
, pp. 1574-1594
-
-
Young, S.G.1
-
3
-
-
0023617743
-
Apolipoprotein B-48 is the product of a messenger RNA with an organ-specific in-frame stop codon
-
Chen, S-H., G. Habib, C-Y. Yang, Z-W. Gu, B. R. Lee, S-A. Weng, S. R. Silberman, S-J. Cai, J. P. Deslypere, M. Rosseneu, A. M. Gotto, Jr., W-H. Li, and L. Chan. 1987. Apolipoprotein B-48 is the product of a messenger RNA with an organ-specific in-frame stop codon. Science. 238: 363-366.
-
(1987)
Science
, vol.238
, pp. 363-366
-
-
Chen, S.-H.1
Habib, G.2
Yang, C.-Y.3
Gu, Z.-W.4
Lee, B.R.5
Weng, S.-A.6
Silberman, S.R.7
Cai, S.-J.8
Deslypere, J.P.9
Rosseneu, M.10
Gotto Jr., A.M.11
Li, W.-H.12
Chan, L.13
-
4
-
-
0023651359
-
A novel form of tissue-specific RNA processing produces apolipoprotein-B48 in intestine
-
Powell, L. M., S. C. Wallis, R. J. Pease, Y. H. Edwards, T. J. Knott, and J. Scott. 1987. A novel form of tissue-specific RNA processing produces apolipoprotein-B48 in intestine. Cell. 50: 831-840.
-
(1987)
Cell
, vol.50
, pp. 831-840
-
-
Powell, L.M.1
Wallis, S.C.2
Pease, R.J.3
Edwards, Y.H.4
Knott, T.J.5
Scott, J.6
-
5
-
-
0023270248
-
Identification of a novel inframe translational stop codon in human intestine apoB mRNA
-
Hospattankar, A. V., K. Higuchi, S. W. Law, N. Meglin, and H. B. Brewer, Jr. 1987. Identification of a novel inframe translational stop codon in human intestine apoB mRNA. Biochem. Biophys. Res. Commun. 148: 279-285.
-
(1987)
Biochem. Biophys. Res. Commun.
, vol.148
, pp. 279-285
-
-
Hospattankar, A.V.1
Higuchi, K.2
Law, S.W.3
Meglin, N.4
Brewer Jr., H.B.5
-
6
-
-
0025362210
-
Apolipoprotein B mRNA editing. Validation of a sensitive assay and developmental biology of RNA editing in the rat
-
Wu, J. H., C. F. Semenkovich, S-H. Chen, W-H. Li, and L. Chan. 1990. Apolipoprotein B mRNA editing. Validation of a sensitive assay and developmental biology of RNA editing in the rat. J. Biol. Chem. 265: 12312-12316.
-
(1990)
J. Biol. Chem.
, vol.265
, pp. 12312-12316
-
-
Wu, J.H.1
Semenkovich, C.F.2
Chen, S.-H.3
Li, W.-H.4
Chan, L.5
-
7
-
-
0025204631
-
Apolipoprotein B messenger RNA editing is developmentally regulated and widely expressed in human tissues
-
Teng, B., M. Verp, J. Salomon, and N. O. Davidson. 1990. Apolipoprotein B messenger RNA editing is developmentally regulated and widely expressed in human tissues. J. Biol. Chem. 265: 20616-20620.
-
(1990)
J. Biol. Chem.
, vol.265
, pp. 20616-20620
-
-
Teng, B.1
Verp, M.2
Salomon, J.3
Davidson, N.O.4
-
8
-
-
0025677193
-
Apolipoprotein B messenger RNA editing is developmentally regulated in pig small intestine: Nucleotide comparison of apolipoprotein B editing regions in five species
-
Teng, B., D. D. Black, and N. O. Davidson. 1990. Apolipoprotein B messenger RNA editing is developmentally regulated in pig small intestine: nucleotide comparison of apolipoprotein B editing regions in five species. Biochem. Biophys. Res. Commun. 173: 74-80.
-
(1990)
Biochem. Biophys. Res. Commun.
, vol.173
, pp. 74-80
-
-
Teng, B.1
Black, D.D.2
Davidson, N.O.3
-
9
-
-
0027085832
-
Developmental and age-related changes in apolipoprotein B mRNA editing in mice
-
Higuchi, K., K. Kitagawa, K. Kogishi, and T. Takeda. 1992. Developmental and age-related changes in apolipoprotein B mRNA editing in mice. J. Lipid Res. 33: 1753-1764.
-
(1992)
J. Lipid Res.
, vol.33
, pp. 1753-1764
-
-
Higuchi, K.1
Kitagawa, K.2
Kogishi, K.3
Takeda, T.4
-
10
-
-
0027172292
-
Apolipoprotein B mRNA editing in 12 different mammalian species: Hepatic expression is reflected in low concentrations of apoB-containing plasma lipoproteins
-
Greeve, J., I. Altkemper, J-H. Dieterich, H. Greten, and E. Windler. 1993. Apolipoprotein B mRNA editing in 12 different mammalian species: hepatic expression is reflected in low concentrations of apoB-containing plasma lipoproteins. J. Lipid Res. 34: 1367-1383.
-
(1993)
J. Lipid Res.
, vol.34
, pp. 1367-1383
-
-
Greeve, J.1
Altkemper, I.2
Dieterich, J.-H.3
Greten, H.4
Windler, E.5
-
11
-
-
0023185681
-
Review of lipid-lowering clinical trials in relation to observational epidemiologic studies
-
Tyroler, H. A. 1987. Review of lipid-lowering clinical trials in relation to observational epidemiologic studies. Circulation. 76: 515-522.
-
(1987)
Circulation
, vol.76
, pp. 515-522
-
-
Tyroler, H.A.1
-
12
-
-
0000743072
-
Association of coronary atherosclerosis with hyperapobetalipoproteinemia [increased protein but normal cholesterol levels in human plasma low density (β) lipoproteins]
-
Sniderman, A., S. Shapiro, D. Marpole, B. Skinner, B. Teng, and P. O. Kwiterovich, Jr. 1980. Association of coronary atherosclerosis with hyperapobetalipoproteinemia [increased protein but normal cholesterol levels in human plasma low density (β) lipoproteins]. Proc. Natl. Acad. Sci. USA. 77: 604-608.
-
(1980)
Proc. Natl. Acad. Sci. USA
, vol.77
, pp. 604-608
-
-
Sniderman, A.1
Shapiro, S.2
Marpole, D.3
Skinner, B.4
Teng, B.5
Kwiterovich Jr., P.O.6
-
13
-
-
0021284889
-
A study of atherosclerosis regression in Macaca mulatta. V. Changes in abdominal aorta and carotid and coronary arteries from animals with atherosclerosis induced for 38 months and then regressed for 24 or 48 months at plasma cholesterol concentrations of 300 or 200 mg/dl
-
Clarkson, T. B., M. G. Bond, B. C. Bullock, K. J. McLaughlin, and J. K. Sawyer. 1984. A study of atherosclerosis regression in Macaca mulatta. V. Changes in abdominal aorta and carotid and coronary arteries from animals with atherosclerosis induced for 38 months and then regressed for 24 or 48 months at plasma cholesterol concentrations of 300 or 200 mg/dl. Exp. Mol. Pathol. 41: 96-118.
-
(1984)
Exp. Mol. Pathol.
, vol.41
, pp. 96-118
-
-
Clarkson, T.B.1
Bond, M.G.2
Bullock, B.C.3
McLaughlin, K.J.4
Sawyer, J.K.5
-
14
-
-
0027145132
-
Transgenic mice expressing high plasma concentrations of human apolipoprotein B100 and lipoprotein[a]
-
Linton, M. F., R. V. Farese, Jr., G. Chiesa, D. S. Grass, P. Chin, R. E. Hammer, H. H. Hobbs, and S. G. Young. 1993. Transgenic mice expressing high plasma concentrations of human apolipoprotein B100 and lipoprotein[a]. J. Clin. Invest. 92: 3029-3037.
-
(1993)
J. Clin. Invest.
, vol.92
, pp. 3029-3037
-
-
Linton, M.F.1
Farese Jr., R.V.2
Chiesa, G.3
Grass, D.S.4
Chin, P.5
Hammer, R.E.6
Hobbs, H.H.7
Young, S.G.8
-
15
-
-
0028293315
-
Expression of human apolipoprotein B and assembly of lipoprotein[a] in transgenic mice
-
Callow, M. J., L. J. Stoltzfus, R. M. Lawn, and E. M. Rubin. 1994. Expression of human apolipoprotein B and assembly of lipoprotein[a] in transgenic mice. Proc. Natl. Acad. Sci. USA. 91: 2130-2134.
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.91
, pp. 2130-2134
-
-
Callow, M.J.1
Stoltzfus, L.J.2
Lawn, R.M.3
Rubin, E.M.4
-
16
-
-
0027365719
-
Expression of human apolipoprotein B-100 in transgenic mice. Editing of human apolipoprotein B-100 mRNA
-
Chiesa, G., D. F. Johnson, Z. Yao, T. L. Innerarity, R. W. Mahley, S. G. Young, R. H. Hammer, and H. H. Hobbs. 1993. Expression of human apolipoprotein B-100 in transgenic mice. Editing of human apolipoprotein B-100 mRNA. J. Biol. Chem. 268: 23747-23750.
-
(1993)
J. Biol. Chem.
, vol.268
, pp. 23747-23750
-
-
Chiesa, G.1
Johnson, D.F.2
Yao, Z.3
Innerarity, T.L.4
Mahley, R.W.5
Young, S.G.6
Hammer, R.H.7
Hobbs, H.H.8
-
17
-
-
0025338872
-
An expression system for human apolipoprotein B-100 in a rat hepatoma cell line
-
Blackhart, B. D., Z. Yao, and B. J. McCarthy. 1990. An expression system for human apolipoprotein B-100 in a rat hepatoma cell line. J. Biol. Chem. 265: 8358-8360.
-
(1990)
J. Biol. Chem.
, vol.265
, pp. 8358-8360
-
-
Blackhart, B.D.1
Yao, Z.2
McCarthy, B.J.3
-
18
-
-
0001372225
-
Introns increase transcriptional efficiency in transgenic mice
-
Brinster, R. L., J. M. Allen, R. R. Behringer, R. E. Gelinas, and R. D. Palmiter. 1988. Introns increase transcriptional efficiency in transgenic mice. Proc. Natl. Acad. Sci. USA. 85: 836-840.
-
(1988)
Proc. Natl. Acad. Sci. USA
, vol.85
, pp. 836-840
-
-
Brinster, R.L.1
Allen, J.M.2
Behringer, R.R.3
Gelinas, R.E.4
Palmiter, R.D.5
-
19
-
-
0025906388
-
A generic intron increases gene expression in transgenic mice
-
Choi, T., M. Huang, C. Gorman, and R. Jaenisch. 1991. A generic intron increases gene expression in transgenic mice. Mol. Cell. Biol. 11: 3070-3074.
-
(1991)
Mol. Cell. Biol.
, vol.11
, pp. 3070-3074
-
-
Choi, T.1
Huang, M.2
Gorman, C.3
Jaenisch, R.4
-
20
-
-
14444270549
-
Genetically modified animal models in cardiovascular research
-
K. R. Chien, J. L. Breslow, J. M. Leiden, R. D. Rosenberg, and C. Seidman, editors. W. B. Saunders, Philadelphia. In press
-
Young, S. G., A. J. Lusis, and R. E. Hammer. 1998. Genetically modified animal models in cardiovascular research. In Molecular Basis of Heart Disease. K. R. Chien, J. L. Breslow, J. M. Leiden, R. D. Rosenberg, and C. Seidman, editors. W. B. Saunders, Philadelphia. In press.
-
(1998)
Molecular Basis of Heart Disease
-
-
Young, S.G.1
Lusis, A.J.2
Hammer, R.E.3
-
21
-
-
0028224225
-
Sequences containing the second-intron enhancer are essential for transcription of the human apolipoprotein B gene in the livers of transgenic mice
-
Brooks, A. R., B. P. Nagy, S. Taylor, W. S. Simonet, J. M. Taylor, and B. Levy-Wilson. 1994. Sequences containing the second-intron enhancer are essential for transcription of the human apolipoprotein B gene in the livers of transgenic mice. Mol. Cell. Biol. 14: 2243-2256.
-
(1994)
Mol. Cell. Biol.
, vol.14
, pp. 2243-2256
-
-
Brooks, A.R.1
Nagy, B.P.2
Taylor, S.3
Simonet, W.S.4
Taylor, J.M.5
Levy-Wilson, B.6
-
22
-
-
0029170118
-
Transcriptional control of the human apolipoprotein B gene in cell culture and in transgenic animals
-
Levy-Wilson, B. 1995. Transcriptional control of the human apolipoprotein B gene in cell culture and in transgenic animals. Prog. Nucleic Acid Res. Mol. Biol. 50: 161-190.
-
(1995)
Prog. Nucleic Acid Res. Mol. Biol.
, vol.50
, pp. 161-190
-
-
Levy-Wilson, B.1
-
23
-
-
0025096719
-
Bacteriophage P1 cloning system for the isolation, amplification, and recovery of DNA fragments as large as 100 kilobase pairs
-
Sternberg, N. 1990. Bacteriophage P1 cloning system for the isolation, amplification, and recovery of DNA fragments as large as 100 kilobase pairs. Proc. Natl. Acad. Sci. USA. 87: 103-107.
-
(1990)
Proc. Natl. Acad. Sci. USA
, vol.87
, pp. 103-107
-
-
Sternberg, N.1
-
24
-
-
0027024025
-
Using bacteriophage P1 system to clone high molecular weight genomic DNA
-
Pierce, J. C., and N. L. Sternberg. 1992. Using bacteriophage P1 system to clone high molecular weight genomic DNA. Methods Enzymol. 216: 549-574.
-
(1992)
Methods Enzymol.
, vol.216
, pp. 549-574
-
-
Pierce, J.C.1
Sternberg, N.L.2
-
26
-
-
0028960478
-
Transgenic mice expressing high levels of human apolipoprotein B develop severe atherosclerotic lesions in response to a high-fat diet
-
Purcell-Huynh, D. A., R. V. Farese, Jr., D. F. Johnson, L. M. Flynn, V. Pierotti, D. L. Newland, M. F. Linton, D. A. Sanan, and S. G. Young. 1995. Transgenic mice expressing high levels of human apolipoprotein B develop severe atherosclerotic lesions in response to a high-fat diet. J. Clin. Invest. 95: 2246-2257.
-
(1995)
J. Clin. Invest.
, vol.95
, pp. 2246-2257
-
-
Purcell-Huynh, D.A.1
Farese Jr., R.V.2
Johnson, D.F.3
Flynn, L.M.4
Pierotti, V.5
Newland, D.L.6
Linton, M.F.7
Sanan, D.A.8
Young, S.G.9
-
27
-
-
0027275449
-
Plasma cholesteryl ester transfer protein
-
Tall, A. R. 1993. Plasma cholesteryl ester transfer protein. J. Lipid Res. 34: 1255-1274.
-
(1993)
J. Lipid Res.
, vol.34
, pp. 1255-1274
-
-
Tall, A.R.1
-
28
-
-
0028937337
-
Plasma cholesteryl ester transfer protein and high-density lipoproteins: New insights from molecular genetic studies
-
Tall, A. R. 1995. Plasma cholesteryl ester transfer protein and high-density lipoproteins: new insights from molecular genetic studies. J. Intern. Med. 237: 5-12.
-
(1995)
J. Intern. Med.
, vol.237
, pp. 5-12
-
-
Tall, A.R.1
-
29
-
-
0029056654
-
Transgenic mice expressing both human apolipoprotein B and human CETP have a lipoprotein cholesterol distribution similar to that of normolipidemic humans
-
Grass, D. S., U. Saini, R. H. Felkner, R. E. Wallace, W. J. P. Lago, S. G. Young, and M. E. Swanson. 1995. Transgenic mice expressing both human apolipoprotein B and human CETP have a lipoprotein cholesterol distribution similar to that of normolipidemic humans. J. Lipid Res. 36: 1082-1091.
-
(1995)
J. Lipid Res.
, vol.36
, pp. 1082-1091
-
-
Grass, D.S.1
Saini, U.2
Felkner, R.H.3
Wallace, R.E.4
Lago, W.J.P.5
Young, S.G.6
Swanson, M.E.7
-
30
-
-
0028783593
-
Overexpression of human apolipoprotein B-100 in transgenic rabbits results in increased levels of LDL and decreased levels of HDL
-
Fan, J., S. P. A. McCormick, R. M. Krauss, S. Taylor, R. Quan, J. M. Taylor, and S. G. Young. 1995. Overexpression of human apolipoprotein B-100 in transgenic rabbits results in increased levels of LDL and decreased levels of HDL. Arterioscler. Thromb. Vasc. Biol. 15: 1889-1899.
-
(1995)
Arterioscler. Thromb. Vasc. Biol.
, vol.15
, pp. 1889-1899
-
-
Fan, J.1
McCormick, S.P.A.2
Krauss, R.M.3
Taylor, S.4
Quan, R.5
Taylor, J.M.6
Young, S.G.7
-
31
-
-
0022483804
-
Mouse preheparin plasma contains high levels of hepatic lipase with low affinity for heparin
-
Peterson, J., G. Bengtsson-Olivecrona, and T. Olivecrona. 1986. Mouse preheparin plasma contains high levels of hepatic lipase with low affinity for heparin. Biochim. Biophys. Acta. 878: 65-70.
-
(1986)
Biochim. Biophys. Acta
, vol.878
, pp. 65-70
-
-
Peterson, J.1
Bengtsson-Olivecrona, G.2
Olivecrona, T.3
-
32
-
-
0031892172
-
Overexpression of hepatic lipase in transgenic mice decreases apolipoprotein B-containing and high density lipoproteins: Evidence that hepatic lipase acts as a ligand for lipoprotein uptake
-
In press
-
Dichek, H. L., W. Brecht, J. Fan, Z-S. Ji, S. P. A. McCormick, H. Akeefe, L. Conzo, D. A. Sanan, K. H. Weisgraber, S. G. Young, J. M. Taylor, and R. W. Mahley. 1998. Overexpression of hepatic lipase in transgenic mice decreases apolipoprotein B-containing and high density lipoproteins: evidence that hepatic lipase acts as a ligand for lipoprotein uptake. J. Biol. Chem. In press.
-
(1998)
J. Biol. Chem.
-
-
Dichek, H.L.1
Brecht, W.2
Fan, J.3
Ji, Z.-S.4
McCormick, S.P.A.5
Akeefe, H.6
Conzo, L.7
Sanan, D.A.8
Weisgraber, K.H.9
Young, S.G.10
Taylor, J.M.11
Mahley, R.W.12
-
33
-
-
0029951819
-
Transgenic mice that overexpress mouse apolipoprotein B. Evidence that the DNA sequences controlling intestinal expression of the apolipoprotein B gene are distant from the structural gene
-
McCormick, S. P. A., J. K. Ng, M. Véniant, J. Borén, V. Pierotti, L. M. Flynn, D. S. Grass, A. Connolly, and S. G. Young. 1996. Transgenic mice that overexpress mouse apolipoprotein B. Evidence that the DNA sequences controlling intestinal expression of the apolipoprotein B gene are distant from the structural gene. J. Biol. Chem. 271: 11963-11970.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 11963-11970
-
-
McCormick, S.P.A.1
Ng, J.K.2
Véniant, M.3
Borén, J.4
Pierotti, V.5
Flynn, L.M.6
Grass, D.S.7
Connolly, A.8
Young, S.G.9
-
34
-
-
15844386541
-
Phenotypic analysis of mice expressing exclusively apolipoprotein B-48 or apolipoprotein B-100
-
Farese, R. V., Jr., M. M. Véniant, C. M. Cham, L. M. Flynn, V. Pierotti, J. F. Loring, M. Traber, S. Ruland, R. S. Stokowski, D. Huszar, and S. G. Young. 1996. Phenotypic analysis of mice expressing exclusively apolipoprotein B-48 or apolipoprotein B-100. Proc. Natl. Acad. Sci. USA. 93: 6393-6398.
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 6393-6398
-
-
Farese Jr., R.V.1
Véniant, M.M.2
Cham, C.M.3
Flynn, L.M.4
Pierotti, V.5
Loring, J.F.6
Traber, M.7
Ruland, S.8
Stokowski, R.S.9
Huszar, D.10
Young, S.G.11
-
35
-
-
0023644898
-
Genetic factors controlling structure and expression of apolipoproteins B and E in mice
-
Lusis, A. J., B. A. Taylor, D. Quon, S. Zollman, and R. C. LeBoeuf. 1987. Genetic factors controlling structure and expression of apolipoproteins B and E in mice. J. Biol. Chem. 262: 7594-7604.
-
(1987)
J. Biol. Chem.
, vol.262
, pp. 7594-7604
-
-
Lusis, A.J.1
Taylor, B.A.2
Quon, D.3
Zollman, S.4
LeBoeuf, R.C.5
-
36
-
-
0010490599
-
Similar low density lipoprotein subclasses in fat-fed human-apoB transgenic mice and humans
-
Abstr
-
Blanche, P. J., M. J. Callow, L. G. Holl, E. M. Rubin, and R. M. Krauss. 1995. Similar low density lipoprotein subclasses in fat-fed human-apoB transgenic mice and humans. Circulation. 92: I-104-I-105 (Abstr).
-
(1995)
Circulation
, vol.92
-
-
Blanche, P.J.1
Callow, M.J.2
Holl, L.G.3
Rubin, E.M.4
Krauss, R.M.5
-
37
-
-
0026766417
-
Ability of the LDL receptor from several animal species to recognize the human apoB binding domain: Studies with LDL from familial defective apoB-100
-
Corsini, A., M. Mazzotti, A. Villa, F. M. Maggi, F. Bernini, L. Romano, C. Romano, R. Fumagalli, and A. L. Catapano. 1992. Ability of the LDL receptor from several animal species to recognize the human apoB binding domain: studies with LDL from familial defective apoB-100. Atherosclerosis. 93: 95-103.
-
(1992)
Atherosclerosis
, vol.93
, pp. 95-103
-
-
Corsini, A.1
Mazzotti, M.2
Villa, A.3
Maggi, F.M.4
Bernini, F.5
Romano, L.6
Romano, C.7
Fumagalli, R.8
Catapano, A.L.9
-
38
-
-
0012389681
-
Metabolism and atherogenicity of apo[a] in transgenic mice
-
X. F. P. Woodford, J. Davignon, and A. Sniderman, editors. Elsevier, Amsterdam
-
Mancini, F. P., V. Mooser, J. Murata, D. Newland, R. E. Hammer, D. A. Sanan, and H. H. Hobbs. 1995. Metabolism and atherogenicity of apo[a] in transgenic mice. In Atherosclerosis X. F. P. Woodford, J. Davignon, and A. Sniderman, editors. Elsevier, Amsterdam. 884-887.
-
(1995)
Atherosclerosis
, pp. 884-887
-
-
Mancini, F.P.1
Mooser, V.2
Murata, J.3
Newland, D.4
Hammer, R.E.5
Sanan, D.A.6
Hobbs, H.H.7
-
39
-
-
0028918775
-
Knockout of the mouse apolipoprotein B gene results in embryonic lethality in homozygotes and protection against diet-induced hypercholesterolemia in heterozygotes
-
Farese, R. V., Jr., S. L. Ruland, L. M. Flynn, R. P. Stokowski, and S. G. Young. 1995. Knockout of the mouse apolipoprotein B gene results in embryonic lethality in homozygotes and protection against diet-induced hypercholesterolemia in heterozygotes. Proc. Natl. Acad. Sci. USA. 92: 1774-1778.
-
(1995)
Proc. Natl. Acad. Sci. USA
, vol.92
, pp. 1774-1778
-
-
Farese Jr., R.V.1
Ruland, S.L.2
Flynn, L.M.3
Stokowski, R.P.4
Young, S.G.5
-
40
-
-
0028800863
-
ApoB gene knockout in mice results in embryonic lethality in homozygotes and neural tube defects, male infertility, and reduced HDL cholesterol ester and apoA-I transport rates in heterozygotes
-
Huang, L-S., E. Voyiaziakis, D. F. Markenson, K. A. Sokol, T. Hayek, and J. L. Breslow. 1995. ApoB gene knockout in mice results in embryonic lethality in homozygotes and neural tube defects, male infertility, and reduced HDL cholesterol ester and apoA-I transport rates in heterozygotes. J. Clin. Invest. 96: 2152-2161.
-
(1995)
J. Clin. Invest.
, vol.96
, pp. 2152-2161
-
-
Huang, L.-S.1
Voyiaziakis, E.2
Markenson, D.F.3
Sokol, K.A.4
Hayek, T.5
Breslow, J.L.6
-
41
-
-
0025322603
-
Synthetic low and high fat diets for the study of atherosclerosis in the mouse
-
Nishina, P. M., J. Verstuyft, and B. Paigen. 1990. Synthetic low and high fat diets for the study of atherosclerosis in the mouse. J. Lipid Res. 31: 859-869.
-
(1990)
J. Lipid Res.
, vol.31
, pp. 859-869
-
-
Nishina, P.M.1
Verstuyft, J.2
Paigen, B.3
-
42
-
-
0027976942
-
Atherosclerosis in mice lacking apoE. Evaluation of lesional development and progression
-
Reddick, R. L., S. H. Zhang, and N. Maeda. 1994. Atherosclerosis in mice lacking apoE. Evaluation of lesional development and progression. Arterioscler. Thromb. 14: 141-147.
-
(1994)
Arterioscler. Thromb.
, vol.14
, pp. 141-147
-
-
Reddick, R.L.1
Zhang, S.H.2
Maeda, N.3
-
43
-
-
0027958084
-
ApoE-deficient mice develop lesions of of all phases of atherosclerosis throughout the arterial tree
-
Nakashima, Y., A. S. Plump, E. W. Raines, J. L. Breslow, and R. Ross. 1994. ApoE-deficient mice develop lesions of of all phases of atherosclerosis throughout the arterial tree. Arterioscler. Thromb. 14: 133-140.
-
(1994)
Arterioscler. Thromb.
, vol.14
, pp. 133-140
-
-
Nakashima, Y.1
Plump, A.S.2
Raines, E.W.3
Breslow, J.L.4
Ross, R.5
-
44
-
-
0029128048
-
Atherogenesis in transgenic mice with human apolipoprotein B and lipoprotein[a]
-
Callow, M. J., J. Verstuyft, R. Tangirala, W. Palinski, and E. M. Rubin. 1995. Atherogenesis in transgenic mice with human apolipoprotein B and lipoprotein[a]. J. Clin. Invest. 96: 1639-1646.
-
(1995)
J. Clin. Invest.
, vol.96
, pp. 1639-1646
-
-
Callow, M.J.1
Verstuyft, J.2
Tangirala, R.3
Palinski, W.4
Rubin, E.M.5
-
45
-
-
0026725757
-
Severe hypercholesterolemia and atherosclerosis in apolipoprotein E-deficiem mice created by homologous recombination in ES cells
-
Plump, A. S., J. D. Smith, T. Hayek, K. Aalto-Setälä, A. Walsh, J. G. Verstuyft, E. M. Rubin, and J. L. Breslow. 1992. Severe hypercholesterolemia and atherosclerosis in apolipoprotein E-deficiem mice created by homologous recombination in ES cells. Cell. 71: 343-353.
-
(1992)
Cell
, vol.71
, pp. 343-353
-
-
Plump, A.S.1
Smith, J.D.2
Hayek, T.3
Aalto-Setälä, K.4
Walsh, A.5
Verstuyft, J.G.6
Rubin, E.M.7
Breslow, J.L.8
-
46
-
-
0026536066
-
Generation of mice carrying a mutant apolipoprotein E gene inactivated by gene targeting in embryonic stem cells
-
Piedrahita, J. A., S. H. Zhang, J. R. Hagaman, P. M. Oliver, and N. Maeda. 1992. Generation of mice carrying a mutant apolipoprotein E gene inactivated by gene targeting in embryonic stem cells. Proc. Natl. Acad. Sci. USA. 89: 4471-4475.
-
(1992)
Proc. Natl. Acad. Sci. USA
, vol.89
, pp. 4471-4475
-
-
Piedrahita, J.A.1
Zhang, S.H.2
Hagaman, J.R.3
Oliver, P.M.4
Maeda, N.5
-
47
-
-
0026592806
-
Spontaneous hypercholesterolemia and arterial lesions in mice lacking apolipoprotein E
-
Zhang, S. H., R. L. Reddick, J. A. Piedrahita, and N. Maeda. 1992. Spontaneous hypercholesterolemia and arterial lesions in mice lacking apolipoprotein E. Science. 258: 468-471.
-
(1992)
Science
, vol.258
, pp. 468-471
-
-
Zhang, S.H.1
Reddick, R.L.2
Piedrahita, J.A.3
Maeda, N.4
-
49
-
-
14444273172
-
Expression of human apolipoprotein B in transgenic mice
-
X. F. P. Woodford, J. Davignon, and A. Sniderman, editors. Elsevier, Amsterdam
-
Young, S. G., S. P. A. McCormick, D. Purcell-Huynh, M. F. Linton, and R. V. Farese, Jr. 1995. Expression of human apolipoprotein B in transgenic mice. In Atherosclerosis X. F. P. Woodford, J. Davignon, and A. Sniderman, editors. Elsevier, Amsterdam. 377-383.
-
(1995)
Atherosclerosis
, pp. 377-383
-
-
Young, S.G.1
McCormick, S.P.A.2
Purcell-Huynh, D.3
Linton, M.F.4
Farese Jr., R.V.5
-
50
-
-
0028821841
-
A genetic model for absent chylomicron formation: Mice producing apolipoprotein B in the liver, but not in the intestine
-
Young, S. G., C. M. Cham, R. E. Pitas, B. J. Burri, A. Connolly, L. Flynn, A. S. Pappu, J. S. Wong, R. L. Hamilton, and R. V. Farese, Jr. 1995. A genetic model for absent chylomicron formation: mice producing apolipoprotein B in the liver, but not in the intestine. J. Clin. Invest. 96: 2932-2946.
-
(1995)
J. Clin. Invest.
, vol.96
, pp. 2932-2946
-
-
Young, S.G.1
Cham, C.M.2
Pitas, R.E.3
Burri, B.J.4
Connolly, A.5
Flynn, L.6
Pappu, A.S.7
Wong, J.S.8
Hamilton, R.L.9
Farese Jr., R.V.10
-
51
-
-
0026329407
-
Similarities and differences in the function of regulatory elements at the 5′ end of the human apolipoprotein B gene in cultured hepatoma (HepG2) and colon carcinoma (CaCo-2) cells
-
Paulweber, B., M. A. Onasch, B. P. Nagy, and B. Levy-Wilson. 1991. Similarities and differences in the function of regulatory elements at the 5′ end of the human apolipoprotein B gene in cultured hepatoma (HepG2) and colon carcinoma (CaCo-2) cells. J. Biol. Chem. 266: 24149-24160.
-
(1991)
J. Biol. Chem.
, vol.266
, pp. 24149-24160
-
-
Paulweber, B.1
Onasch, M.A.2
Nagy, B.P.3
Levy-Wilson, B.4
-
52
-
-
0026726174
-
Organization of the regulatory elements and nuclear activities participating in the transcription of the human apolipoprotein B gene
-
Kardassis, D., V. I. Zannis, and C. Cladaras. 1992. Organization of the regulatory elements and nuclear activities participating in the transcription of the human apolipoprotein B gene. J. Biol. Chem. 267: 2622-2632.
-
(1992)
J. Biol. Chem.
, vol.267
, pp. 2622-2632
-
-
Kardassis, D.1
Zannis, V.I.2
Cladaras, C.3
-
53
-
-
0009492302
-
Human apolipoprotein (apo-) B transgenic mice from 210-kb and 145-kb bacterial artificial chromosomes: Apo-B gene expression in the intestine is controlled by a distant regulatory element
-
Abstr.
-
Nielsen, L. B., S. P. McCormick, J. K. Ng, V. Pierotti, H. Shizuya, and S. G. Young. 1996. Human apolipoprotein (apo-) B transgenic mice from 210-kb and 145-kb bacterial artificial chromosomes: apo-B gene expression in the intestine is controlled by a distant regulatory element. Circulation. 94: I-631 (Abstr.).
-
(1996)
Circulation
, vol.94
-
-
Nielsen, L.B.1
McCormick, S.P.2
Ng, J.K.3
Pierotti, V.4
Shizuya, H.5
Young, S.G.6
-
54
-
-
0030662044
-
Human apolipoprotein B transgenic mice generated with 210-kb and 145-kb bacterial artificial chromosomes. Evidence that a distant 5′ element confers appropriate transgene expression in the intestine
-
In press
-
Nielsen, L. B., S. P. A. McCormick, V. Pierotti, C. Tam, M. D. Gunn, H. Shizuya, and S. G. Young. 1998. Human apolipoprotein B transgenic mice generated with 210-kb and 145-kb bacterial artificial chromosomes. Evidence that a distant 5′ element confers appropriate transgene expression in the intestine. J. Biol. Chem. In press.
-
(1998)
J. Biol. Chem.
-
-
Nielsen, L.B.1
McCormick, S.P.A.2
Pierotti, V.3
Tam, C.4
Gunn, M.D.5
Shizuya, H.6
Young, S.G.7
-
55
-
-
0028800213
-
Mutagenesis of the human apolipoprotein B gene in a yeast artificial chromosome reveals the site of attachment for apolipoprotein[a]
-
McCormick, S. P. A., J. K. Ng, S. Taylor, L. M. Flynn, R. E. Hammer, and S. G. Young. 1995. Mutagenesis of the human apolipoprotein B gene in a yeast artificial chromosome reveals the site of attachment for apolipoprotein[a]. Proc. Natl Acad. Sci. USA. 92: 10147-10151.
-
(1995)
Proc. Natl Acad. Sci. USA
, vol.92
, pp. 10147-10151
-
-
McCormick, S.P.A.1
Ng, J.K.2
Taylor, S.3
Flynn, L.M.4
Hammer, R.E.5
Young, S.G.6
-
56
-
-
0030064273
-
Generation of transgenic mice from yeast artificial chromosome DNA that has been modified by gene targeting
-
McCormick, S. P. A., K. R. Peterson, R. E. Hammer, C. H. Clegg, and S. G. Young. 1996. Generation of transgenic mice from yeast artificial chromosome DNA that has been modified by gene targeting. Trends Cardiovasc. Med. 6: 16-24.
-
(1996)
Trends Cardiovasc. Med.
, vol.6
, pp. 16-24
-
-
McCormick, S.P.A.1
Peterson, K.R.2
Hammer, R.E.3
Clegg, C.H.4
Young, S.G.5
-
57
-
-
0009453976
-
Replacement of chromosome segments with altered DNA sequences constructed in vitro
-
Scherer, S., and R. W. Davis. 1979, Replacement of chromosome segments with altered DNA sequences constructed in vitro. Prof. Natl. Acad. Sci. USA. 76: 4951-4955.
-
(1979)
Prof. Natl. Acad. Sci. USA
, vol.76
, pp. 4951-4955
-
-
Scherer, S.1
Davis, R.W.2
-
58
-
-
0025979877
-
Targeting, disruption, replacement, and allele rescue: Integrative DNA transformation in yeast
-
Rothstein, R. 1991. Targeting, disruption, replacement, and allele rescue: integrative DNA transformation in yeast. Methods Enzymol. 194: 281-301.
-
(1991)
Methods Enzymol.
, vol.194
, pp. 281-301
-
-
Rothstein, R.1
-
59
-
-
0029073038
-
Use of yeast artificial chromosomes (YACs) in studies of mammalian development: Production of β-globin locus YAC mice carrying human globin developmental mutants
-
Peterson, K. R., Q-L. Li, C. H. Clegg, T. Furukawa, P. A. Navas, E. J. Norton, T. G. Kimbrough, and G. Stamatoyannopoulos. 1995. Use of yeast artificial chromosomes (YACs) in studies of mammalian development: production of β-globin locus YAC mice carrying human globin developmental mutants. Prof. Natl. Acad. Sci. USA. 92: 5655-5659.
-
(1995)
Prof. Natl. Acad. Sci. USA
, vol.92
, pp. 5655-5659
-
-
Peterson, K.R.1
Li, Q.-L.2
Clegg, C.H.3
Furukawa, T.4
Navas, P.A.5
Norton, E.J.6
Kimbrough, T.G.7
Stamatoyannopoulos, G.8
-
60
-
-
0027261194
-
Transgenic mice containing a 248-kb yeast artificial chromosome carrying the human β-globin locus display proper developmental control of human globin genes
-
Peterson, K. R., C. H. Clegg, C. Huxley, B. M. Josephson, H. S. Haugen, T. Funikawa, and G. Stamatoyannopoulos. 1993. Transgenic mice containing a 248-kb yeast artificial chromosome carrying the human β-globin locus display proper developmental control of human globin genes. Proc. Natl. Acad. Sci. USA. 90: 7593-7597.
-
(1993)
Proc. Natl. Acad. Sci. USA
, vol.90
, pp. 7593-7597
-
-
Peterson, K.R.1
Clegg, C.H.2
Huxley, C.3
Josephson, B.M.4
Haugen, H.S.5
Funikawa, T.6
Stamatoyannopoulos, G.7
-
61
-
-
0027464687
-
A yeast artificial chromosome covering the tyrosinase gene confers copy number-dependent expression in transgenic mice
-
Schedl, A., L. Montoliu, G. Kelsey, and G. Schütz. 1993. A yeast artificial chromosome covering the tyrosinase gene confers copy number-dependent expression in transgenic mice. Nature. 362: 258-261.
-
(1993)
Nature
, vol.362
, pp. 258-261
-
-
Schedl, A.1
Montoliu, L.2
Kelsey, G.3
Schütz, G.4
-
62
-
-
0026500036
-
Molecular complementation of a collagen mutation in mammalian cells using yeast artificial chromosomes
-
Strauss, W. M., and R. Jaenisch. 1992. Molecular complementation of a collagen mutation in mammalian cells using yeast artificial chromosomes. EMBO J. 11: 417-422.
-
(1992)
EMBO J.
, vol.11
, pp. 417-422
-
-
Strauss, W.M.1
Jaenisch, R.2
-
63
-
-
0026349985
-
Selective cleavage of human DNA: RecA-assisted restriction endonuclease (RARE) cleavage
-
Ferrin, L. J., and R. D. Camerini-Otero. 1991. Selective cleavage of human DNA: RecA-assisted restriction endonuclease (RARE) cleavage. Science. 254: 1494-1497.
-
(1991)
Science
, vol.254
, pp. 1494-1497
-
-
Ferrin, L.J.1
Camerini-Otero, R.D.2
-
64
-
-
2642649961
-
Transgenic mice expressing recombinant low density lipoproteins with defective receptor binding
-
Abstr.
-
Borén, J., W. Zhu, I. Lee, and T. L. Innerarity. 1996. Transgenic mice expressing recombinant low density lipoproteins with defective receptor binding. Circulation. 94: I-104 (Abstr.).
-
(1996)
Circulation
, vol.94
-
-
Borén, J.1
Zhu, W.2
Lee, I.3
Innerarity, T.L.4
-
66
-
-
0030765353
-
Transgenic mice expressing human apoB-95 and apoB-97. Evidence that sequences within the carboxyl-terminal portion of human apoB-100 are important for the assembly of lipoprotein[a]
-
McCormick, S. P. A., J. K. Ng, C. M. Cham, S. Taylor, S. M. Marcovina, J. P. Segrest, R. E. Hammer, and S. G. Young. 1997. Transgenic mice expressing human apoB-95 and apoB-97. Evidence that sequences within the carboxyl-terminal portion of human apoB-100 are important for the assembly of lipoprotein[a]. J. Biol. Chem. 272: 23616-23622.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 23616-23622
-
-
McCormick, S.P.A.1
Ng, J.K.2
Cham, C.M.3
Taylor, S.4
Marcovina, S.M.5
Segrest, J.P.6
Hammer, R.E.7
Young, S.G.8
-
67
-
-
0028864606
-
Site-specific mutagenesis demonstrates that cysteine 4326 of apolipoprotein B is required for covalent linkage with apolipoprotein [a] in vivo
-
Callow, M. J., and E. M. Rubin. 1995. Site-specific mutagenesis demonstrates that cysteine 4326 of apolipoprotein B is required for covalent linkage with apolipoprotein [a] in vivo. J. Biol. Chem. 270: 23914-23917.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 23914-23917
-
-
Callow, M.J.1
Rubin, E.M.2
-
68
-
-
0028131455
-
Expression of human apolipoprotein B-90 in transgenic mice. Demonstration that apolipoprotein B-90 lacks the structural requirements to form lipoprotein[a]
-
McCormick, S. P. A., M. F. Linton, H. H. Hobbs, S. Taylor, L. K. Curtiss, and S. G. Young. 1994. Expression of human apolipoprotein B-90 in transgenic mice. Demonstration that apolipoprotein B-90 lacks the structural requirements to form lipoprotein[a]. J. Biol. Chem. 269: 24284-24289.
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 24284-24289
-
-
McCormick, S.P.A.1
Linton, M.F.2
Hobbs, H.H.3
Taylor, S.4
Curtiss, L.K.5
Young, S.G.6
-
70
-
-
0028141451
-
Carboxyl-terminal truncation of apolipoprotein B-100 inhibits lipoprotein[a] particle formation
-
Gabel, B., Z. Yao, R. S. McLeod, S. G. Young, and M. L. Koschinsky. 1994. Carboxyl-terminal truncation of apolipoprotein B-100 inhibits lipoprotein[a] particle formation. FEBS Lett. 350: 77-81.
-
(1994)
FEBS Lett.
, vol.350
, pp. 77-81
-
-
Gabel, B.1
Yao, Z.2
McLeod, R.S.3
Young, S.G.4
Koschinsky, M.L.5
-
71
-
-
0029824973
-
A simple and efficient method for making site-directed mutants, deletions, and fusions of large DNA such as P1 and BAC clones
-
Borén, J., I. Lee, M. J. Callow, E. M. Rubin, and T. L. Innerarity. 1996. A simple and efficient method for making site-directed mutants, deletions, and fusions of large DNA such as P1 and BAC clones. Genome Res. 6: 1123-1130.
-
(1996)
Genome Res.
, vol.6
, pp. 1123-1130
-
-
Borén, J.1
Lee, I.2
Callow, M.J.3
Rubin, E.M.4
Innerarity, T.L.5
-
72
-
-
0024558892
-
Association between a specific apolipoprotein B mutation and familial defective apolipoprotein B-100
-
Soria, L. F., E. H. Ludwig, H. R. G. Clarke, G. L. Vega, S. M. Grundy, and B. J. McCarthy. 1989. Association between a specific apolipoprotein B mutation and familial defective apolipoprotein B-100. Proc. Natl. Acad. Sci. USA. 86: 587-591.
-
(1989)
Proc. Natl. Acad. Sci. USA
, vol.86
, pp. 587-591
-
-
Soria, L.F.1
Ludwig, E.H.2
Clarke, H.R.G.3
Vega, G.L.4
Grundy, S.M.5
McCarthy, B.J.6
-
73
-
-
0029090626
-
Independent mutations at codon 3500 of the apolipoprotein B gene are associated with hyperlipidemia
-
Gaffney, D., J. M. Reid, I. M. Cameron, K. Vass, M. J. Caslake, J. Shepherd, and C. J. Packard. 1995. Independent mutations at codon 3500 of the apolipoprotein B gene are associated with hyperlipidemia. Arterioscler. Thromb. Vasc. Biol. 15: 1025-1029.
-
(1995)
Arterioscler. Thromb. Vasc. Biol.
, vol.15
, pp. 1025-1029
-
-
Gaffney, D.1
Reid, J.M.2
Cameron, I.M.3
Vass, K.4
Caslake, M.J.5
Shepherd, J.6
Packard, C.J.7
-
74
-
-
0022340735
-
Human apolipoprotein B: Structure of carboxyl-terminal domains, sites of gene expression, and chromosomal localization
-
Knott, T. J., S. C. Rall, Jr., T. L. Innerarity, S. F. Jacobson, M. S. Urdea, B. Levy-Wilson, L. M. Powell, R. J. Pease, R. Eddy, H. Nakai, M. Byers, L. M. Priestley, E. Robertson, L. B. Rall, C. Betsholtz, T. B. Shows, R. W. Mahley, and J. Scott. 1985. Human apolipoprotein B: structure of carboxyl-terminal domains, sites of gene expression, and chromosomal localization. Science. 230: 37-43.
-
(1985)
Science
, vol.230
, pp. 37-43
-
-
Knott, T.J.1
Rall Jr., S.C.2
Innerarity, T.L.3
Jacobson, S.F.4
Urdea, M.S.5
Levy-Wilson, B.6
Powell, L.M.7
Pease, R.J.8
Eddy, R.9
Nakai, H.10
Byers, M.11
Priestley, L.M.12
Robertson, E.13
Rall, L.B.14
Betsholtz, C.15
Shows, T.B.16
Mahley, R.W.17
Scott, J.18
-
75
-
-
0023007238
-
Complete protein sequence and identification of structural domains of human apolipoprotein B
-
Knott, T. J., R. J. Pease, L. M. Powell, S. C. Wallis, S. C. Rall, Jr., T. L. Innerarity, B. Blackhart, W. H. Taylor, Y. Marcel, R. Milne, D. Johnson, M. Fuller, A. J. Lusis, B. J. McCarthy, R. W. Mahley, B. Levy-Wilson, and J. Scott. 1986. Complete protein sequence and identification of structural domains of human apolipoprotein B. Nature. 323: 734-738.
-
(1986)
Nature
, vol.323
, pp. 734-738
-
-
Knott, T.J.1
Pease, R.J.2
Powell, L.M.3
Wallis, S.C.4
Rall Jr., S.C.5
Innerarity, T.L.6
Blackhart, B.7
Taylor, W.H.8
Marcel, Y.9
Milne, R.10
Johnson, D.11
Fuller, M.12
Lusis, A.J.13
McCarthy, B.J.14
Mahley, R.W.15
Levy-Wilson, B.16
Scott, J.17
-
76
-
-
0027478167
-
Targeted modification of the apolipoprotein B gene results in hypobetalipoproteinemia and developmental abnormalities in mice
-
Homanics, G. E., T. J. Smith, S. H. Zhang, D. Lee, S. G. Young, and N. Maeda. 1993. Targeted modification of the apolipoprotein B gene results in hypobetalipoproteinemia and developmental abnormalities in mice. Proc. Natl. Acad. Sci. USA. 90: 2389-2393.
-
(1993)
Proc. Natl. Acad. Sci. USA
, vol.90
, pp. 2389-2393
-
-
Homanics, G.E.1
Smith, T.J.2
Zhang, S.H.3
Lee, D.4
Young, S.G.5
Maeda, N.6
-
77
-
-
0028961719
-
Exencephaly and hydrocephaly in mice with targeted modification of the apolipoprotein B (Apob) gene
-
Homanics, G. E., N. Maeda, M. G. Traber, H. J. Kayden, D. B. Dehart, and K. K. Sulik. 1995. Exencephaly and hydrocephaly in mice with targeted modification of the apolipoprotein B (Apob) gene. Teratology. 51: 1-10.
-
(1995)
Teratology
, vol.51
, pp. 1-10
-
-
Homanics, G.E.1
Maeda, N.2
Traber, M.G.3
Kayden, H.J.4
Dehart, D.B.5
Sulik, K.K.6
-
78
-
-
0006895351
-
The intra-uterine changes in the pregnant albino rat (Mus norvegicus) deprived of vitamin E
-
Urner, J. A. 1931. The intra-uterine changes in the pregnant albino rat (Mus norvegicus) deprived of vitamin E. Anat. Rec. 50: 175-187.
-
(1931)
Anat. Rec.
, vol.50
, pp. 175-187
-
-
Urner, J.A.1
-
79
-
-
0009640768
-
Gross observations on developing abnormal embryos induced by maternal vitamin E deficiency
-
Cheng, D. W., L. F. Chang, and T. A. Bairnson. 1957. Gross observations on developing abnormal embryos induced by maternal vitamin E deficiency. Anat. Rec. 129: 167-185.
-
(1957)
Anat. Rec.
, vol.129
, pp. 167-185
-
-
Cheng, D.W.1
Chang, L.F.2
Bairnson, T.A.3
-
80
-
-
0018756436
-
Metabolic studies in an unusual case of asymptomatic familial hypobetalipoproteinemia with hypoalphalipoproteinemia and fasting chylomicronemia
-
Steinberg, D., S. M. Gnindy, H. Y. I. Mok, J. D. Turner, D. B. Weinstein, W. V. Brown, and J. J. Albers. 1979. Metabolic studies in an unusual case of asymptomatic familial hypobetalipoproteinemia with hypoalphalipoproteinemia and fasting chylomicronemia. J. Clin. Invest. 64: 292-301.
-
(1979)
J. Clin. Invest.
, vol.64
, pp. 292-301
-
-
Steinberg, D.1
Gnindy, S.M.2
Mok, H.Y.I.3
Turner, J.D.4
Weinstein, D.B.5
Brown, W.V.6
Albers, J.J.7
-
81
-
-
0030608379
-
Two distinct apolipoprotein B alleles in mice generated by a single "in-out" targeting
-
Toth, L. R., T. J. Smith, C. Jones, H. V. de Silva, O. Smithies, and N. Maeda. 1996. Two distinct apolipoprotein B alleles in mice generated by a single "in-out" targeting. Gene. 178: 161-168.
-
(1996)
Gene
, vol.178
, pp. 161-168
-
-
Toth, L.R.1
Smith, T.J.2
Jones, C.3
De Silva, H.V.4
Smithies, O.5
Maeda, N.6
-
82
-
-
0030323065
-
Using genetically modified mice to study apolipoprotein B
-
Young, S. G. 1996. Using genetically modified mice to study apolipoprotein B. J. Atheroscler. Thromb. 3: 62-74.
-
(1996)
J. Atheroscler. Thromb.
, vol.3
, pp. 62-74
-
-
Young, S.G.1
-
83
-
-
0029933263
-
A novel function for apolipoprotein B: Lipoprotein synthesis in the yolk sac is critical for maternal-fetal lipid transport in mice
-
Farese, R. V., Jr., S. Cases, S. L. Ruland, H. J. Kayden, J. S. Wong, S. G. Young, and R. L. Hamilton. 1996. A novel function for apolipoprotein B: lipoprotein synthesis in the yolk sac is critical for maternal-fetal lipid transport in mice. J. Lipid Res. 37: 347-360.
-
(1996)
J. Lipid Res.
, vol.37
, pp. 347-360
-
-
Farese Jr., R.V.1
Cases, S.2
Ruland, S.L.3
Kayden, H.J.4
Wong, J.S.5
Young, S.G.6
Hamilton, R.L.7
-
84
-
-
0029993449
-
Know your neighbors: Three phenotypes in null mutants of the myogenic bHLH gene MRF4
-
Olson, E. N., H-H. Arnold, P. W. J. Rigby, and B. J. Wold. 1996. Know your neighbors: three phenotypes in null mutants of the myogenic bHLH gene MRF4. Cell. 85: 1-4.
-
(1996)
Cell
, vol.85
, pp. 1-4
-
-
Olson, E.N.1
Arnold, H.-H.2
Rigby, P.W.J.3
Wold, B.J.4
-
85
-
-
0026770668
-
High-fidelity gene targeting in embryonic stem cells by using sequence replacement vectors
-
Thomas, K. R., C. Deng, and M. R. Capecchi. 1992. High-fidelity gene targeting in embryonic stem cells by using sequence replacement vectors. Mol. Cell. Biol. 12: 2919-2923.
-
(1992)
Mol. Cell. Biol.
, vol.12
, pp. 2919-2923
-
-
Thomas, K.R.1
Deng, C.2
Capecchi, M.R.3
-
86
-
-
0028330133
-
The molecular basis of abetalipoproteinemia
-
Gregg, R. E., and J. R. Wetterau. 1994. The molecular basis of abetalipoproteinemia. Curr. Opin. Lipidol. 5: 81-86.
-
(1994)
Curr. Opin. Lipidol.
, vol.5
, pp. 81-86
-
-
Gregg, R.E.1
Wetterau, J.R.2
-
87
-
-
0001903995
-
Disorders of the biogenesis and secretion of lipoproteins containing the B apolipoproteins
-
C. R. Scriver, A. L. Beaudet, W. S. Sly, and D. Valle, editors. McGraw-Hill, New York
-
Kane, J. P., and R. J. Havel. 1989. Disorders of the biogenesis and secretion of lipoproteins containing the B apolipoproteins. In The Metabolic Basis of Inherited Disease. 6th edition. C. R. Scriver, A. L. Beaudet, W. S. Sly, and D. Valle, editors. McGraw-Hill, New York. 1139-1164.
-
(1989)
The Metabolic Basis of Inherited Disease. 6th Edition
, pp. 1139-1164
-
-
Kane, J.P.1
Havel, R.J.2
-
88
-
-
0026429190
-
Introduction of a subtle mutation into the Hox-2.6 locus in embryonic stem cells
-
Hasty, P., R. Ramírez-Solis, R. Krumlauf, and A. Bradley. 1991. Introduction of a subtle mutation into the Hox-2.6 locus in embryonic stem cells. Nature. 350: 243-246.
-
(1991)
Nature
, vol.350
, pp. 243-246
-
-
Hasty, P.1
Ramírez-Solis, R.2
Krumlauf, R.3
Bradley, A.4
-
89
-
-
0026100231
-
Testing an "in-out" targeting procedure for making subtle genomic modifications in mouse embryonic stem cells
-
Valancius, V., and O. Smithies. 1991. Testing an "in-out" targeting procedure for making subtle genomic modifications in mouse embryonic stem cells. Mol. Cell. Biol. 11: 1402-1408.
-
(1991)
Mol. Cell. Biol.
, vol.11
, pp. 1402-1408
-
-
Valancius, V.1
Smithies, O.2
-
90
-
-
0028268018
-
The two-receptor model of lipoprotein clearance: Tests of the hypothesis in "knockout" mice lacking the low density lipoprotein receptor, apolipoprotein E, or both proteins
-
Ishibashi, S., J. Herz, N. Maeda, J. L. Goldstein, and M. S. Brown. 1994. The two-receptor model of lipoprotein clearance: tests of the hypothesis in "knockout" mice lacking the low density lipoprotein receptor, apolipoprotein E, or both proteins. Proc. Natl. Acad. Sci. USA. 91: 4431-4435.
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.91
, pp. 4431-4435
-
-
Ishibashi, S.1
Herz, J.2
Maeda, N.3
Goldstein, J.L.4
Brown, M.S.5
-
91
-
-
0028284556
-
Inhibition of hepatic chylomicron remnant uptake by gene transfer of a receptor antagonist
-
Willnow, T. E., Z. Sheng, S. Ishibashi, and J. Herz. 1994. Inhibition of hepatic chylomicron remnant uptake by gene transfer of a receptor antagonist. Science. 264: 1471-1474.
-
(1994)
Science
, vol.264
, pp. 1471-1474
-
-
Willnow, T.E.1
Sheng, Z.2
Ishibashi, S.3
Herz, J.4
-
92
-
-
0242695290
-
Susceptibility to atherosclerosis in mice expressing exclusively apolipoprotein B-48 or apolipoprotein B-100
-
Véniant, M. M., V. Pierotti, D. Newland, C. M. Cham, D. A. Sanan, R. L. Walzern, and S. G. Young. 1997. Susceptibility to atherosclerosis in mice expressing exclusively apolipoprotein B-48 or apolipoprotein B-100. J. Clin. Invest. 100: 180-188.
-
(1997)
J. Clin. Invest.
, vol.100
, pp. 180-188
-
-
Véniant, M.M.1
Pierotti, V.2
Newland, D.3
Cham, C.M.4
Sanan, D.A.5
Walzern, R.L.6
Young, S.G.7
-
93
-
-
0026694431
-
Apolipoprotein B gene mutations affecting cholesterol levels
-
Farese, R. V., Jr., M. F. Linton, and S. G. Young. 1992. Apolipoprotein B gene mutations affecting cholesterol levels. J. Intern. Med. 231: 643-652.
-
(1992)
J. Intern. Med.
, vol.231
, pp. 643-652
-
-
Farese Jr., R.V.1
Linton, M.F.2
Young, S.G.3
-
94
-
-
0026554719
-
A truncated species of apolipoprotein B, B-83, associated with hypobetalipoproteinemia
-
Farese, R. V., Jr., A. Garg, V. R. Pierotti, G. L. Vega, and S. G. Young. 1992. A truncated species of apolipoprotein B, B-83, associated with hypobetalipoproteinemia. J. Lipid Res. 33: 569-577.
-
(1992)
J. Lipid Res.
, vol.33
, pp. 569-577
-
-
Farese Jr., R.V.1
Garg, A.2
Pierotti, V.R.3
Vega, G.L.4
Young, S.G.5
-
95
-
-
15844406352
-
Non-sense mutations inhibit RNA splicing in a cell-free system: Recognition of mutant codon is independent of protein synthesis
-
Aoufouchi, S., J. Yélamos, and G. Milstein. 1996. Non-sense mutations inhibit RNA splicing in a cell-free system: recognition of mutant codon is independent of protein synthesis. Cell. 85: 415-422.
-
(1996)
Cell
, vol.85
, pp. 415-422
-
-
Aoufouchi, S.1
Yélamos, J.2
Milstein, G.3
-
96
-
-
0024121631
-
Nonsense mutadons in the human β-globin gene affect mRNA metabolism
-
Baserga, S. J., and E. J. Benz, Jr. 1988. Nonsense mutadons in the human β-globin gene affect mRNA metabolism. Proc. Natl. Acad. Sci. USA. 85: 2056-2060.
-
(1988)
Proc. Natl. Acad. Sci. USA
, vol.85
, pp. 2056-2060
-
-
Baserga, S.J.1
Benz Jr., E.J.2
-
97
-
-
0030010752
-
Effects of nonsense mutations on nuclear and cytoplasmic adenine phosphoribosyltransferase RNA
-
Kessler, O., and L. A. Chasin. 1996. Effects of nonsense mutations on nuclear and cytoplasmic adenine phosphoribosyltransferase RNA. Mol. Cell. Biol. 16: 4426-4435.
-
(1996)
Mol. Cell. Biol.
, vol.16
, pp. 4426-4435
-
-
Kessler, O.1
Chasin, L.A.2
-
98
-
-
0029330286
-
When cells stop making sense: Effects of nonsense codons on RNA metabolism in vertebrate cells
-
Maquat, L. E. 1995. When cells stop making sense: effects of nonsense codons on RNA metabolism in vertebrate cells. RNA. 1: 453-465.
-
(1995)
RNA
, vol.1
, pp. 453-465
-
-
Maquat, L.E.1
-
99
-
-
0024349521
-
Nonsense mutations in the dihydrofolate reductase gene affect RNA processing
-
Urlaub, G., P. J. Mitchell, C. J. Ciudad, and L. A. Chasin. 1989. Nonsense mutations in the dihydrofolate reductase gene affect RNA processing. Mol. Cell. Biol. 9: 2868-2880.
-
(1989)
Mol. Cell. Biol.
, vol.9
, pp. 2868-2880
-
-
Urlaub, G.1
Mitchell, P.J.2
Ciudad, C.J.3
Chasin, L.A.4
-
100
-
-
0024353035
-
Two distinct truncated apolipoprotein B species in a kindred with hypobetalipoproteinemia
-
Krul, E. S., M. Kinoshita, P. Talmud, S. E. Humphries, S. Turner, A. C. Goldberg, K. Cook, E. Boerwinkle, and G. Schonfeld. 1989. Two distinct truncated apolipoprotein B species in a kindred with hypobetalipoproteinemia. Arteriosclerosis. 9: 856-868.
-
(1989)
Arteriosclerosis
, vol.9
, pp. 856-868
-
-
Krul, E.S.1
Kinoshita, M.2
Talmud, P.3
Humphries, S.E.4
Turner, S.5
Goldberg, A.C.6
Cook, K.7
Boerwinkle, E.8
Schonfeld, G.9
-
101
-
-
0026065365
-
Preparation of clone libraries in yeast artificial-chromosome vectors
-
Burke, D. T., and M. V. Olson. 1991. Preparation of clone libraries in yeast artificial-chromosome vectors. Methods Enzymol. 194: 251-270.
-
(1991)
Methods Enzymol.
, vol.194
, pp. 251-270
-
-
Burke, D.T.1
Olson, M.V.2
-
102
-
-
0026498273
-
Reconstitution of lipoprotein[a] by infusion of human low density lipoprotein into transgenic mice expressing human apolipoprotein[a]
-
Chiesa, G., H. H. Hobbs, M. L. Koschinsky, R. M. Lawn, S. D. Maika, and R. E. Hammer. 1992. Reconstitution of lipoprotein[a] by infusion of human low density lipoprotein into transgenic mice expressing human apolipoprotein[a]. J. Biol. Chem. 267: 24369-24374.
-
(1992)
J. Biol. Chem.
, vol.267
, pp. 24369-24374
-
-
Chiesa, G.1
Hobbs, H.H.2
Koschinsky, M.L.3
Lawn, R.M.4
Maika, S.D.5
Hammer, R.E.6
-
103
-
-
0028985381
-
Effect of the number of apolipoprotein[a] kringle 4 domains on immunochemical measurements of lipoprotein[a]
-
Marcovina, S. M., J. J. Albers, B. Gabel, M. L. Koschinsky, and V. P. Gaur. 1995. Effect of the number of apolipoprotein[a] kringle 4 domains on immunochemical measurements of lipoprotein[a]. Clin. Chem. 41: 246-255.
-
(1995)
Clin. Chem.
, vol.41
, pp. 246-255
-
-
Marcovina, S.M.1
Albers, J.J.2
Gabel, B.3
Koschinsky, M.L.4
Gaur, V.P.5
-
104
-
-
0028832488
-
Relative contributions of apolipoprotein[a] and apolipoprotein-B to the development of fatty lesions in the proximal aorta of mice
-
Mancini, F. P., D. L. Newland, V. Mooser, J. Murata, S. Marcovina, S. G. Young, R. E. Hammer, D. A. Sanan, and H. H. Hobbs. 1995. Relative contributions of apolipoprotein[a] and apolipoprotein-B to the development of fatty lesions in the proximal aorta of mice. Arterioscler. Thromb. Vasc. Biol. 15: 1911-1916.
-
(1995)
Arterioscler. Thromb. Vasc. Biol.
, vol.15
, pp. 1911-1916
-
-
Mancini, F.P.1
Newland, D.L.2
Mooser, V.3
Murata, J.4
Marcovina, S.5
Young, S.G.6
Hammer, R.E.7
Sanan, D.A.8
Hobbs, H.H.9
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