Dual mechanisms for the low plasma levels of truncated apolipoprotein B proteins in familial hypobetalipoproteinemia. Analysis of a new mouse model with a nonsense mutation in the Apob gene

Journal of Clinical Investigation

Volumn 101, Issue 6, 1998, Pages 1468-1477

  Kim, Edward ^a,b,c   Cham, Candace M ^a   Véniant, Murielle M ^a   Ambroziak, Patricia ^a   Young, Stephen G ^a,b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c GLADSTONE INSTITUTE OF CARDIOVASCULAR DISEASE   (United States)

Author keywords

Cholesterol; Exencephalus; Hypolipidemia; Lipoproteins; mRNA stability; Nonsense mutations

Indexed keywords

APOLIPOPROTEIN B; APOLIPOPROTEIN B100; CHOLESTEROL; MESSENGER RNA;

ANIMAL CELL; ANIMAL MODEL; ARTICLE; EXENCEPHALY; GENE TARGETING; HYPOBETALIPOPROTEINEMIA; LIPOPROTEIN BLOOD LEVEL; MOUSE; MUTANT; NONHUMAN; NONSENSE MUTATION; PRIORITY JOURNAL;

ALLELES; ANIMALS; APOLIPOPROTEIN B-100; APOLIPOPROTEINS B; APOLIPOPROTEINS E; CHOLESTEROL; CLONING, MOLECULAR; DNA, COMPLEMENTARY; HYPOBETALIPOPROTEINEMIAS; INTESTINES; LIPOPROTEINS, HDL; LIPOPROTEINS, LDL; LIPOPROTEINS, VLDL; LIVER; MICE; MICE, MUTANT STRAINS; MUTAGENESIS, SITE-DIRECTED; PEDIGREE; POLYMERASE CHAIN REACTION; RECEPTORS, LDL; RNA, MESSENGER; TRANSCRIPTION, GENETIC;

EID: 0032521141     PISSN: 00219738     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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