Deficiency of a protein-repair enzyme results in the accumulation of altered proteins, retardation of growth, and fatal seizures in mice

Proceedings of the National Academy of Sciences of the United States of America

Volumn 94, Issue 12, 1997, Pages 6132-6137

  Kim, Edward ^a,b   Lowenson, Jonathan D ^c   Maclaren, Duncan C ^c   Clarke, Steven ^a,c   Young, Stephen G ^a,b  

^a GLADSTONE INSTITUTE OF CARDIOVASCULAR DISEASE   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ASPARAGINE; ASPARTATE AMINOTRANSFERASE; ASPARTIC ACID; METHYLTRANSFERASE;

ANIMAL CELL; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CYTOSOL; EMBRYO; ENZYME ACTIVITY; ENZYME DEFICIENCY; ESTERIFICATION; GENE TARGETING; GROWTH RETARDATION; MOUSE; NERVOUS SYSTEM DEVELOPMENT; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN VARIANT; SEIZURE; SUDDEN DEATH;

ANIMALS; ASPARAGINE; ASPARTIC ACID; BODY WEIGHT; DEATH, SUDDEN; DNA PRIMERS; FEMALE; GROWTH DISORDERS; HETEROZYGOTE; HUMANS; INFANT, NEWBORN; MALE; MICE; MICE, KNOCKOUT; PENTYLENETETRAZOLE; POLYMERASE CHAIN REACTION; PROTEIN D-ASPARTATE-L-ISOASPARTATE METHYLTRANSFERASE; PROTEIN METHYLTRANSFERASES; PROTEINS; RECOMBINANT PROTEINS; RESTRICTION MAPPING; SEIZURES;

EID: 0030995490     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.94.12.6132     Document Type: Article

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