Metallothionein expression in prostatic carcinoma: Correlation with Gleason grade, pathologic stage, DNA content and serum level of prostate-specific antigen

Clinical and Investigative Medicine

Volumn 20, Issue 6, 1997, Pages 371-380

  Moussa, Madeleine ^a,b   Kloth, Debra ^a   Peers, Gary ^a   Cherian, M George ^a   Frei, John V ^a   Chin, Joseph L ^a  

^a UNIVERSITY OF WESTERN ONTARIO   (Canada)

^b LONDON HEALTH SCIENCES CENTRE   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

METALLOTHIONEIN; PROSTATE SPECIFIC ANTIGEN;

ANIMAL TISSUE; ARTICLE; BLOOD LEVEL; CANCER GRADING; CELL CYCLE S PHASE; CELL PROLIFERATION; CORRELATION FUNCTION; DNA CONTENT; HUMAN; IMMUNOHISTOCHEMISTRY; MALE; PLOIDY; PRIORITY JOURNAL; PROSTATE ADENOCARCINOMA; PROSTATE CARCINOMA; PROSTATECTOMY; PROTEIN EXPRESSION; STAINING;

DNA, NEOPLASM; FLOW CYTOMETRY; HUMANS; IMMUNOHISTOCHEMISTRY; KERATINS; MALE; METALLOTHIONEIN; NEOPLASM STAGING; PLOIDIES; PROSTATE; PROSTATE-SPECIFIC ANTIGEN; PROSTATIC NEOPLASMS; RETROSPECTIVE STUDIES; S PHASE; TUMOR MARKERS, BIOLOGICAL;

EID: 0031435182     PISSN: 0147958X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (34)

1. Cherian MG, Goyer RA. Metallothioneins and their role in the metabolism and toxicity of metals. Life Sci 1978;23:1-8.
2. Kagi JHR, Vasak M, Lerch K, Gilg DEO, Hunziker P, Bernhard WR, et al. Structure of mammalian metallothionein. Environ Health Perspect 1984;54:93-103.
3. Nartey N, Banerjee D, Cherian MG. Immunohistochemical localization of metallothionein in cell nucleus and cytoplasm of fetal human liver and kidney and its changes during development. Pathology 1987;19:233-8.
4. Kagi JHR, Kojima Y. Chemistry and biochemistry of metallothionein. In: Kagi JHR and Kojima Y, editors. Metallothionein II. Basel, Switzerland: Birkhauser Verlag; 1987. p. 25-61.
5. Liu J, Kershaw WC, Klaassen CD. Rat primary hepatocyte cultures are a good model for examining metallothionein-induced tolerance to cadmium toxicity. In Vitro Cell Dev Biol 1990;26:75-9.
6. Andrews PA, Murphy MP, Howell SB. Metallothionein-mediated cisplatin resistance in human ovarian carcinoma cells. Cancer Chemother Pharmacol 1987;19: 149-54.
7. Satoh M, Naganuma A, Imura N. Metallothionein induction prevents toxic side effects of cisplatin and adriamycin used in combination. Cancer Chemother Pharmacol 1988;21:176-8.
8. Wood DP, Klein JE, Fair WR, Chaganti RSK. Metallothionein gene expression in bladder cancer exposed to cisplatin. Mod Pathol 1993;6:33-5.
9. Waalkes MP, Diwan BA, Weghorst CM, et al. Further study of the tumor suppressive effects of cadmium in the B6C3F1 mouse liver and lung: late stage vulnerability of tumor to cadmium and the role of metallothionein. J Pharmacol Exp Ther 1993;226:1656-63.
10. Richards MP, Cousins RJ. Metallothionein and its relationship to the metabolism of dietary zinc in rats. J Nutr 1976;106:1591-6.
11. Onosaka S, Tanaka K, Cherian MG. Effects of cadmium and zinc on tissue levels of metallothionein. Environ Health Perspect 1984;54:67-72.
12. Satoh M, Kondo Y, Mita M, et al. Prevention of carcinogenicity of anticancer drugs by metallothionein induction. Cancer Res 1993;53:4767-8.
13. Kelley SL, Basu A, Teicher BA, et al. Overexpression of metallothionein confers resistance to anticancer drugs. Science 1988;241:1813-5.
14. Koropatnick J, Pearson J. Zinc treatment, metallothionein expression, and resistance to cisplatin in mouse melanoma cells. Somat Cell Mol Genet 1990;16:529-37.
15. Cherian MG, Huang PC, Klaassen CD, et al. National Cancer Institute Workshop on the possible roles of metallothionein in carcinogenesis. Cancer Res 1993;53: 922-5.
16. Nartey N, Cherian MG, Banerjee D. Immunohistochemical localization of metallothionein in human thyroid tumors. Am J Pathol 1987;129:177-82.
17. Chauvin PJ, Cherian MG, Wysocki GP, Pringle GA. A comparison of metallothionein expression in human normal and neoplastic salivary gland tissue using immunohistochemistry [abstract]. Toxicologist 1992;12:379.
18. Kontozoglou TE, Banerjee D, Cherian MG. Immunohistochemical localization of metallothionein in human testicular embryonal carcinoma cells. Virchows Arch A Pathol Pathol Anat 1989;415:545-9.
19. Chin JL, Banerjee D, Kadhim SA, Kontozoglou TE, Chauvin PJ, Cherian MG. Metallothionein in testicular germ cell tumors and drug resistance: clinical correlation. Cancer 1993;72:3029-35.
20. Bahnson RR, Banner BF, Ernstoff MS, Lazo JS, Cherian MG, Banerjee D, et al. Immunohistochemical localization of metallothionein in transitional cell carcinoma of the bladder. J Urol 1991;46:1518-20.
21. Umeyama T, Saruki K, Imai K, Yamanaka H, Suzuki K, Ikei N, et al. Immunohistochemical demonstration of metallothionein in the rat prostate. Prostate 1987;10:257-64.
22. Coogan TP, Shiraishi N, Waalkes MP. Apparent quiescence of the metallothionein gene in the rat ventral prostate: association with cadmium-induced prostate tumors in rats. Environ Health Perspect 1994;102:137-42.
23. Suzuki T, Umeyama T, Ohma C, et al. Immunohistochemical study of metallothionein in normal and benign prostatic hyperplasia of human prostate. Prostate 1991;19:35-42.
24. Zhang XH, Jin L, Sakamoto H, Takenaka I. Immunohistochemical localization of metallothionein in human prostate cancer. J Urol 1996;156:1679-81.
25. Cleason DF. Histologic grading of prostate cancer: a perspective. Hum Pathol 1992;23:273-9.
26. Hedley DW, Friedlander ML, Taylor IW. Application of DNA flow cytometry to paraffin-embedded archival material for the treatment of aneuploidy and its clinical significance. Cytometry 1985;6:327-33.
27. Frei JV, Martinez VJ. DNA flow cytometry of fresh and paraffin-embedded tissue using cytokeratin staining. Mod Pathol 1993;6:599-604.
28. Meskel HH, Cherian MG, Martinez VJ, Veinot LA, Frei JV. Metallothionein as an epithelial proliferative compartment marker for DNA flow cytometry. Mod Pathol 1993;6:755-60.
29. Panemangalore M, Banerjee D, Onosaka S, Cherian MG. Changes in the intracellular accumulation and distribution of metallothionein in rat liver and kidney during postnatal development. Dev Biol 1983;97:95-102.
30. Templeton DM, Banerjee D, Cherian MG. Metallothionein synthesis and localization in relation to metal storage in rat liver during gestation. Can J Cell Biol 1985;63:6-22.
31. National Cancer Institute roundtable on prostate cancer: future research directions. Cancer Res 1991;51:2498-505.
32. Kondo Y, Kuo SM, Watkins SC, Lazo JS. Metallothionein localization and cisplatin resistance in human hormone-independent prostatic tumor cell lines. Cancer Res 1995;55:474-7.
33. Zeng J, Vallee BL, Kagi JHR. Zinc transfer from transcription factor III A fingers to thionein clusters. Proc Natl Acad Sci USA 1991;88:9984-8.
34. O'Malley FP, Grignon DJ, Keeney M, et al. DNA heterogeneity in prostatic adenocarcinoma. Cancer 1993;71(9):2797-802.