메뉴 건너뛰기




Volumn 53, Issue 2, 1997, Pages 223-231

pH dependence of methotrexate transport by the reduced folate carrier and the folate receptor in L1210 leukemia cells. Further evidence for a third route mediated at low pH

Author keywords

binding; folate receptor; methotrexate; reduced folate carrier; transport

Indexed keywords

FOLATE BINDING PROTEIN; METHOTREXATE;

EID: 0031021010     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-2952(96)00730-7     Document Type: Article
Times cited : (57)

References (41)
  • 1
    • 0015246387 scopus 로고
    • The characteristics of the membrane transport of amethopterin and the naturally occurring folates
    • Goldman ID, The characteristics of the membrane transport of amethopterin and the naturally occurring folates. Ann NY Acad Sci 186: 400-422, 1971.
    • (1971) Ann NY Acad Sci , vol.186 , pp. 400-422
    • Goldman, I.D.1
  • 2
    • 0026456523 scopus 로고
    • Multiple folate transport systems in L1210 cells
    • Fan J, Vitols KS and Huennekens FM, Multiple folate transport systems in L1210 cells. Adv Enzyme Regul 32: 3-15, 1992.
    • (1992) Adv Enzyme Regul , vol.32 , pp. 3-15
    • Fan, J.1    Vitols, K.S.2    Huennekens, F.M.3
  • 3
    • 0025336152 scopus 로고
    • Folate-binding proteins
    • Henderson GB, Folate-binding proteins. Annu Rev Nutr 10: 319-335, 1990.
    • (1990) Annu Rev Nutr , vol.10 , pp. 319-335
    • Henderson, G.B.1
  • 4
    • 0010597057 scopus 로고
    • Correlates of folate analog transport, pharmacokinetics and selective antitumor action
    • Ed. Goldman ID. Pergamon Press, Oxford
    • Sirotnak FM, Correlates of folate analog transport, pharmacokinetics and selective antitumor action. In: Membrane Transport of Antineoplastic Agents (Ed. Goldman ID), pp. 241-281. Pergamon Press, Oxford, 1986.
    • (1986) Membrane Transport of Antineoplastic Agents , pp. 241-281
    • Sirotnak, F.M.1
  • 5
    • 0014410041 scopus 로고
    • Carrier-mediated transport of the folic acid analogue, methotrexate, in the L1210 leukemia cell
    • Goldman ID, Lichtenstein NS and Oliverio VT, Carrier-mediated transport of the folic acid analogue, methotrexate, in the L1210 leukemia cell. J Biol Chem 243: 5007-5017, 1968.
    • (1968) J Biol Chem , vol.243 , pp. 5007-5017
    • Goldman, I.D.1    Lichtenstein, N.S.2    Oliverio, V.T.3
  • 6
    • 0021838288 scopus 로고
    • The cellular pharmacology of methotrexate
    • Goldman ID and Matherly LH, The cellular pharmacology of methotrexate. Pharmacol Ther 28: 77-102, 1985.
    • (1985) Pharmacol Ther , vol.28 , pp. 77-102
    • Goldman, I.D.1    Matherly, L.H.2
  • 7
    • 0022353539 scopus 로고
    • Obligate genetic expression in tumor cells of a fetal membrane property mediating "folate" transport: Biological significance and implications for improved therapy of human cancer
    • Sirotnak FM, Obligate genetic expression in tumor cells of a fetal membrane property mediating "folate" transport: Biological significance and implications for improved therapy of human cancer. Cancer Res 45: 3992-4000, 1985.
    • (1985) Cancer Res , vol.45 , pp. 3992-4000
    • Sirotnak, F.M.1
  • 8
    • 0027982786 scopus 로고
    • A novel cDNA restores reduced folate carrier activity and methotrexate sensitivity to transport deficient cells
    • Dixon KH, Lanpher BC, Chiu J, Kelley K and Cowan KH, A novel cDNA restores reduced folate carrier activity and methotrexate sensitivity to transport deficient cells. J Biol Chem 269: 17-20, 1994.
    • (1994) J Biol Chem , vol.269 , pp. 17-20
    • Dixon, K.H.1    Lanpher, B.C.2    Chiu, J.3    Kelley, K.4    Cowan, K.H.5
  • 9
    • 0027963626 scopus 로고
    • Isolation of a hamster cDNA clone coding for a function involved in methotrexate uptake
    • Williams FMR, Murray RC, Underhill TM and Flintoff WF, Isolation of a hamster cDNA clone coding for a function involved in methotrexate uptake. J Biol Chem 269: 5810-5816, 1994.
    • (1994) J Biol Chem , vol.269 , pp. 5810-5816
    • Williams, F.M.R.1    Murray, R.C.2    Underhill, T.M.3    Flintoff, W.F.4
  • 10
    • 0029151314 scopus 로고
    • Characterization of a mutation in the reduced folate carrier in a transport defective L1210 murine leukemia cell line
    • Brigle KE, Spinella MJ, Sierra EE and Goldman ID, Characterization of a mutation in the reduced folate carrier in a transport defective L1210 murine leukemia cell line. J Biol Chem 270: 22974-22979, 1995.
    • (1995) J Biol Chem , vol.270 , pp. 22974-22979
    • Brigle, K.E.1    Spinella, M.J.2    Sierra, E.E.3    Goldman, I.D.4
  • 11
    • 0029084385 scopus 로고
    • Isolation of human cDNAs that restore methotrexate sensitivity and reduced folate carrier activity in methotrexate transport-defective Chinese hamster ovary cells
    • Wong SC, Proefke SA, Bhushan A and Matherly LH, Isolation of human cDNAs that restore methotrexate sensitivity and reduced folate carrier activity in methotrexate transport-defective Chinese hamster ovary cells. J Biol Chem 270: 17468-17475, 1995.
    • (1995) J Biol Chem , vol.270 , pp. 17468-17475
    • Wong, S.C.1    Proefke, S.A.2    Bhushan, A.3    Matherly, L.H.4
  • 12
    • 0023683407 scopus 로고
    • Delivery of folates to the cytoplasm of MA104 cells is mediated by a surface membrane receptor that recycles
    • Kamen BA, Wang M, Streckfuss AJ, Peryea X and Anderson RGW, Delivery of folates to the cytoplasm of MA104 cells is mediated by a surface membrane receptor that recycles. J Biol Chem 263: 13602-13609, 1988.
    • (1988) J Biol Chem , vol.263 , pp. 13602-13609
    • Kamen, B.A.1    Wang, M.2    Streckfuss, A.J.3    Peryea, X.4    Anderson, R.G.W.5
  • 13
    • 0026545612 scopus 로고
    • Potocytosis: Sequestration and transport of small molecules by caveolae
    • Anderson RGW, Kamen BA, Rothberg KG and Lacey SW, Potocytosis: Sequestration and transport of small molecules by caveolae. Science 255: 410-411, 1992.
    • (1992) Science , vol.255 , pp. 410-411
    • Anderson, R.G.W.1    Kamen, B.A.2    Rothberg, K.G.3    Lacey, S.W.4
  • 14
    • 0025275523 scopus 로고
    • Characteristics of a novel transport system for folate compounds in wild-type and methotrexate-resistant L1210 cells
    • Henderson GB and Strauss BP, Characteristics of a novel transport system for folate compounds in wild-type and methotrexate-resistant L1210 cells. Cancer Res 50: 1709-1714, 1990.
    • (1990) Cancer Res , vol.50 , pp. 1709-1714
    • Henderson, G.B.1    Strauss, B.P.2
  • 15
    • 0020972452 scopus 로고
    • Relationships between carrier-mediated transport of folate compounds by L1210 leukemia cells: Evidence for multiplicity of entry routes with different kinetic properties expressed in plasma membrane vesicles
    • Yang C, Dembo M and Sirotnak FM, Relationships between carrier-mediated transport of folate compounds by L1210 leukemia cells: Evidence for multiplicity of entry routes with different kinetic properties expressed in plasma membrane vesicles. J Membr Biol 75: 11-20, 1983.
    • (1983) J Membr Biol , vol.75 , pp. 11-20
    • Yang, C.1    Dembo, M.2    Sirotnak, F.M.3
  • 16
    • 0014690663 scopus 로고
    • Transport energetics of the folic acid analogue, methotrexate, in L1210 cells: Enhanced accumulation by metabolic inhibitors
    • Goldman ID, Transport energetics of the folic acid analogue, methotrexate, in L1210 cells: Enhanced accumulation by metabolic inhibitors. J Biol Chem 244: 3779-3785, 1969.
    • (1969) J Biol Chem , vol.244 , pp. 3779-3785
    • Goldman, I.D.1
  • 17
    • 0021252202 scopus 로고
    • Transport routes utilized by L1210 cells for the influx and efflux of methotrexate
    • Henderson GB and Zevely EM, Transport routes utilized by L1210 cells for the influx and efflux of methotrexate. J Biol Chem 259: 1526-1531, 1984.
    • (1984) J Biol Chem , vol.259 , pp. 1526-1531
    • Henderson, G.B.1    Zevely, E.M.2
  • 18
    • 0027378617 scopus 로고
    • Altered expression of unidirectional extrusion routes for methotrexate and cholate in an efflux variant of L1210 cells
    • Henderson GB and Hughes TR, Altered expression of unidirectional extrusion routes for methotrexate and cholate in an efflux variant of L1210 cells. Biochim Biophys Acta 1152: 91-98, 1993.
    • (1993) Biochim Biophys Acta , vol.1152 , pp. 91-98
    • Henderson, G.B.1    Hughes, T.R.2
  • 19
    • 0030580806 scopus 로고    scopus 로고
    • Identification of efflux systems for large anions and anionic conjugates as the mediators of methotrexate efflux in L1210 cells
    • Saxena M and Henderson GB, Identification of efflux systems for large anions and anionic conjugates as the mediators of methotrexate efflux in L1210 cells. Biochem Pharmacol 51: 975-982, 1996.
    • (1996) Biochem Pharmacol , vol.51 , pp. 975-982
    • Saxena, M.1    Henderson, G.B.2
  • 20
    • 0019498699 scopus 로고
    • Folate transport in isolated brush border membrane vesicles from rat intestine
    • Selhub J and Rosenberg IH, Folate transport in isolated brush border membrane vesicles from rat intestine. J Biol Chem 256: 4489-4493, 1981.
    • (1981) J Biol Chem , vol.256 , pp. 4489-4493
    • Selhub, J.1    Rosenberg, I.H.2
  • 21
    • 0022380156 scopus 로고
    • The transmembrane pH gradient drives uphill folate transport in rabbit jejenum
    • Schron CM, Washington C and Blitzer BL, The transmembrane pH gradient drives uphill folate transport in rabbit jejenum. J Clin Invest 76: 2030-2033, 1985.
    • (1985) J Clin Invest , vol.76 , pp. 2030-2033
    • Schron, C.M.1    Washington, C.2    Blitzer, B.L.3
  • 22
    • 0027477407 scopus 로고
    • Transport of folates and antifolates in liver
    • Home DW, Transport of folates and antifolates in liver. Proc Soc Exp Biol Med 202: 385-391, 1993.
    • (1993) Proc Soc Exp Biol Med , vol.202 , pp. 385-391
    • Home, D.W.1
  • 24
    • 0023836526 scopus 로고
    • Folate binding and transport by rat kidney brush-border membrane vesicles
    • Bhandari SD, Joshi SK and McMartin KE, Folate binding and transport by rat kidney brush-border membrane vesicles. Biochem Biophys Acta 937: 211-218, 1988.
    • (1988) Biochem Biophys Acta , vol.937 , pp. 211-218
    • Bhandari, S.D.1    Joshi, S.K.2    McMartin, K.E.3
  • 25
    • 0028884105 scopus 로고
    • Comparison of transport properties of the reduced folate carrier and folate receptor in murine L1210 leukemia cells
    • Sierra EE, Brigle KE, Spinella MJ and Goldman ID, Comparison of transport properties of the reduced folate carrier and folate receptor in murine L1210 leukemia cells. Biochem Pharmacol 50: 1287-1294, 1995.
    • (1995) Biochem Pharmacol , vol.50 , pp. 1287-1294
    • Sierra, E.E.1    Brigle, K.E.2    Spinella, M.J.3    Goldman, I.D.4
  • 26
    • 0023130109 scopus 로고
    • The effects of 4-aminoantifolates on 5-formyltetrahydrofolate metabolism in L1210 cells
    • Matherly LH, Barlowe CK, Phillips VM and Goldman ID, The effects of 4-aminoantifolates on 5-formyltetrahydrofolate metabolism in L1210 cells. J Biol Chem 262: 710-717, 1987.
    • (1987) J Biol Chem , vol.262 , pp. 710-717
    • Matherly, L.H.1    Barlowe, C.K.2    Phillips, V.M.3    Goldman, I.D.4
  • 27
    • 0024452418 scopus 로고
    • Membrane protein changes in an L1210 leukemia cell line with a translocation defect in the methotrexate-tetrahydrofolate cofactor transport carrier
    • Schuetz JD, Westin EH, Matherly LH, Pincus R, Swerdlow PS and Goldman ID, Membrane protein changes in an L1210 leukemia cell line with a translocation defect in the methotrexate-tetrahydrofolate cofactor transport carrier. J Biol Chem 264: 16261-16267, 1989.
    • (1989) J Biol Chem , vol.264 , pp. 16261-16267
    • Schuetz, J.D.1    Westin, E.H.2    Matherly, L.H.3    Pincus, R.4    Swerdlow, P.S.5    Goldman, I.D.6
  • 28
    • 0028111514 scopus 로고
    • Increased expression and genomic organization of a folate-binding protein homologous to the human placental isoform in L1210 murine leukemia cell lines with a defective reduced folate carrier
    • Brigle KE, Seither RL, Westin EH and Goldman ID, Increased expression and genomic organization of a folate-binding protein homologous to the human placental isoform in L1210 murine leukemia cell lines with a defective reduced folate carrier. J Biol Chem 269: 4267-4272, 1994.
    • (1994) J Biol Chem , vol.269 , pp. 4267-4272
    • Brigle, K.E.1    Seither, R.L.2    Westin, E.H.3    Goldman, I.D.4
  • 29
    • 0020471606 scopus 로고
    • Further studies on the charge-related alterations of methotrexate transport in Ehrlich ascites tumor cells by ionic liposomes: Correlation with liposomecell association
    • Fry DW and Goldman ID, Further studies on the charge-related alterations of methotrexate transport in Ehrlich ascites tumor cells by ionic liposomes: Correlation with liposomecell association. J Membr Biol 66: 87-95, 1982.
    • (1982) J Membr Biol , vol.66 , pp. 87-95
    • Fry, D.W.1    Goldman, I.D.2
  • 31
    • 0028008481 scopus 로고
    • Increased expression and characterization of two distinct folate binding proteins in murine erythroleukemia cells
    • Brigle KE, Spinella MJ, Westin EH and Goldman ID, Increased expression and characterization of two distinct folate binding proteins in murine erythroleukemia cells. Biochem Pharmacol 47: 337-345, 1994.
    • (1994) Biochem Pharmacol , vol.47 , pp. 337-345
    • Brigle, K.E.1    Spinella, M.J.2    Westin, E.H.3    Goldman, I.D.4
  • 32
    • 0028986856 scopus 로고
    • Distinguishing between folate receptor-α-mediated transport and reduced folate carrier-mediated transport in L1210 leukemia cells
    • Spinella MJ, Brigle KE, Sierra EE and Goldman ID, Distinguishing between folate receptor-α-mediated transport and reduced folate carrier-mediated transport in L1210 leukemia cells. J Biol Chem 270: 7842-7849, 1995.
    • (1995) J Biol Chem , vol.270 , pp. 7842-7849
    • Spinella, M.J.1    Brigle, K.E.2    Sierra, E.E.3    Goldman, I.D.4
  • 33
    • 0022530424 scopus 로고
    • Properties of a folate binding protein (FBP) isolated from porcine kidney
    • Kamen BA and Gaston JD, Properties of a folate binding protein (FBP) isolated from porcine kidney. Biochem Pharmacol 35: 2323-2329, 1986.
    • (1986) Biochem Pharmacol , vol.35 , pp. 2323-2329
    • Kamen, B.A.1    Gaston, J.D.2
  • 34
    • 0017735327 scopus 로고
    • Acidic dissociation constants of folic acid, dihydrofolic acid, and methotrexate
    • Poe M, Acidic dissociation constants of folic acid, dihydrofolic acid, and methotrexate. J Biol Chem 252: 3724-3728, 1977.
    • (1977) J Biol Chem , vol.252 , pp. 3724-3728
    • Poe, M.1
  • 37
    • 0025859444 scopus 로고
    • Analysis of the pH dependence of folate binding and transport by rat kidney brush border membrane vesicles
    • Bhandari SD, Fortney T and McMartin KE, Analysis of the pH dependence of folate binding and transport by rat kidney brush border membrane vesicles. Proc Soc Exp Biol Med 196: 451-456, 1991.
    • (1991) Proc Soc Exp Biol Med , vol.196 , pp. 451-456
    • Bhandari, S.D.1    Fortney, T.2    McMartin, K.E.3
  • 38
    • 0014723162 scopus 로고
    • The transport of pteroylglutamic acid across the small intestine of the rat
    • Smith ME, Matty AJ and Blair JA, The transport of pteroylglutamic acid across the small intestine of the rat. Biochim Biophys Acta 219: 37-46, 1970.
    • (1970) Biochim Biophys Acta , vol.219 , pp. 37-46
    • Smith, M.E.1    Matty, A.J.2    Blair, J.A.3
  • 39
    • 0025332357 scopus 로고
    • + and pH dependence of 5-methyltetrahydrofolic acid and methotrexate transport in freshly isolated hepatocytes
    • + and pH dependence of 5-methyltetrahydrofolic acid and methotrexate transport in freshly isolated hepatocytes. Biochim Biophys Acta 1023: 47-55, 1990.
    • (1990) Biochim Biophys Acta , vol.1023 , pp. 47-55
    • Horne, D.W.1
  • 40
    • 0025376172 scopus 로고
    • Carrier affinity as a mechanism for the pH-dependence of folate transport in the small intestine
    • Mason JB, Shoda R, Haskell M, Selhub J and Rosenberg IH, Carrier affinity as a mechanism for the pH-dependence of folate transport in the small intestine. Biochim Biophys Acta 1024: 331-335, 1990.
    • (1990) Biochim Biophys Acta , vol.1024 , pp. 331-335
    • Mason, J.B.1    Shoda, R.2    Haskell, M.3    Selhub, J.4    Rosenberg, I.H.5
  • 41
    • 0026099595 scopus 로고
    • pH modulation of the kinetics of rabbit jejunal, brush-border folate transport
    • Schron CM, pH Modulation of the kinetics of rabbit jejunal, brush-border folate transport. J Membr Biol 120: 192-200, 1990.
    • (1990) J Membr Biol , vol.120 , pp. 192-200
    • Schron, C.M.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.