메뉴 건너뛰기




Volumn 100, Issue 1-2, 1999, Pages 181-189

Immune regulation and CNS autoimmune disease

Author keywords

[No Author keywords available]

Indexed keywords

BASIC FIBROBLAST GROWTH FACTOR; BRAIN DERIVED NEUROTROPHIC FACTOR; CHEMOKINE; CHEMOKINE RECEPTOR; CYTOKINE; GLATIRAMER; GLUTAMATE AMMONIA LIGASE; GLUTAMATE DEHYDROGENASE; METALLOPROTEINASE; MYELIN PROTEIN; NEUROTROPHIN; NITRIC OXIDE;

EID: 0033399126     PISSN: 01655728     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0165-5728(99)00186-1     Document Type: Article
Times cited : (39)

References (96)
  • 1
    • 0032476565 scopus 로고    scopus 로고
    • Bystander suppression of experimental autoimmune encephalomyelitis by T cell lines and clones of the Th2 type induced by copolymer 1
    • Aharoni R., Teitelbaum D., Sela M., Arnon R. Bystander suppression of experimental autoimmune encephalomyelitis by T cell lines and clones of the Th2 type induced by copolymer 1. J. Neuroimmunol. 91:1998;135-146.
    • (1998) J. Neuroimmunol. , vol.91 , pp. 135-146
    • Aharoni, R.1    Teitelbaum, D.2    Sela, M.3    Arnon, R.4
  • 2
    • 0033083789 scopus 로고    scopus 로고
    • CD40-CD154 interaction and IFN-gamma are required for IL-12 but not prostaglandin E2 secretion by microglia during antigen presentation to Th1 cells
    • Aloisi F., Penna G., Polazzi E., Minghetti L., Adorini L. CD40-CD154 interaction and IFN-gamma are required for IL-12 but not prostaglandin E2 secretion by microglia during antigen presentation to Th1 cells. J. Immunol. 162:1999;1384-1391.
    • (1999) J. Immunol. , vol.162 , pp. 1384-1391
    • Aloisi, F.1    Penna, G.2    Polazzi, E.3    Minghetti, L.4    Adorini, L.5
  • 3
    • 0027317921 scopus 로고
    • The attraction of adhesion molecules
    • editorial
    • Antel J.P., Owens T. The attraction of adhesion molecules. Ann. Neurol. 34:1993;123-124. editorial.
    • (1993) Ann. Neurol. , vol.34 , pp. 123-124
    • Antel, J.P.1    Owens, T.2
  • 4
    • 4243293190 scopus 로고    scopus 로고
    • Vaccination with an altered MBP-peptide induces a persistent immune response
    • Antel J., Qin Y., Zhang D., Crowe P., Conlon P. Vaccination with an altered MBP-peptide induces a persistent immune response. Neurology. 52:1999;A264-A264.
    • (1999) Neurology , vol.52
    • Antel, J.1    Qin, Y.2    Zhang, D.3    Crowe, P.4    Conlon, P.5
  • 5
    • 0031228204 scopus 로고    scopus 로고
    • Changes in cytokine secretion induced by altered peptide ligands of myelin basic protein peptide 85-99
    • Ausubel L.J., Krieger J.I., Hafler D.A. Changes in cytokine secretion induced by altered peptide ligands of myelin basic protein peptide 85-99. J. Immunol. 159:1997;2502-2512.
    • (1997) J. Immunol. , vol.159 , pp. 2502-2512
    • Ausubel, L.J.1    Krieger, J.I.2    Hafler, D.A.3
  • 6
    • 0032499260 scopus 로고    scopus 로고
    • Chemokines and leukocyte traffic
    • Baggiolini M. Chemokines and leukocyte traffic. Nature. 392:1998;565-568.
    • (1998) Nature , vol.392 , pp. 565-568
    • Baggiolini, M.1
  • 7
    • 0033536062 scopus 로고    scopus 로고
    • CCR5(+) and CXCR3(+) T cells are increased in multiple sclerosis and their ligands MIP-1alpha and IP-10 are expressed in demyelinating brain lesions
    • Balashov K.E., Rottman J.B., Weiner H.L., Hancock W.W. CCR5(+) and CXCR3(+) T cells are increased in multiple sclerosis and their ligands MIP-1alpha and IP-10 are expressed in demyelinating brain lesions. Proc. Natl. Acad. Sci. U.S.A. 96:1999;6873-6878.
    • (1999) Proc. Natl. Acad. Sci. U.S.A. , vol.96 , pp. 6873-6878
    • Balashov, K.E.1    Rottman, J.B.2    Weiner, H.L.3    Hancock, W.W.4
  • 8
    • 0029451821 scopus 로고
    • The role of macrophages, perivascular cells, and microglial cells in the pathogenesis of experimental autoimmune encephalomyelitis
    • Bauer J., Huitinga I., Zhao W., Lassmann H., Hickey W.F., Dijkstra C.D. The role of macrophages, perivascular cells, and microglial cells in the pathogenesis of experimental autoimmune encephalomyelitis. Glia. 15:1995;437-446.
    • (1995) Glia , vol.15 , pp. 437-446
    • Bauer, J.1    Huitinga, I.2    Zhao, W.3    Lassmann, H.4    Hickey, W.F.5    Dijkstra, C.D.6
  • 10
    • 0030250932 scopus 로고    scopus 로고
    • Comparison of phenotypic and functional properties of immediately ex vivo and cultured human adult microglia
    • Becher B., Antel J.P. Comparison of phenotypic and functional properties of immediately ex vivo and cultured human adult microglia. Glia. 18:1996;1-10.
    • (1996) Glia , vol.18 , pp. 1-10
    • Becher, B.1    Antel, J.P.2
  • 11
    • 0033992220 scopus 로고    scopus 로고
    • CD40 engagement stimulates IL-12 p70 production by human microglial cells: Basis for Th1 polarization in the CNS
    • in press
    • Becher, B., Blain, M., Antel, J. CD40 engagement stimulates IL-12 p70 production by human microglial cells: basis for Th1 polarization in the CNS. J. Neuroimmunol., in press.
    • J. Neuroimmunol.
    • Becher, B.1    Blain, M.2    Antel, J.3
  • 12
    • 0029847274 scopus 로고    scopus 로고
    • Soluble tumor necrosis factor receptor inhibits interleukin 12 production by stimulated human adult microglial cells in vitro
    • Becher B., Dodelet V., Fedorowicz V., Antel J.P. Soluble tumor necrosis factor receptor inhibits interleukin 12 production by stimulated human adult microglial cells in vitro. J. Clin. Invest. 98:1996;1539-1543.
    • (1996) J. Clin. Invest , vol.98 , pp. 1539-1543
    • Becher, B.1    Dodelet, V.2    Fedorowicz, V.3    Antel, J.P.4
  • 13
    • 0032193696 scopus 로고    scopus 로고
    • IL-10 is critical in the regulation of autoimmune encephalomyelitis as demonstrated by studies of IL-10- And IL-4-deficient and transgenic mice
    • Bettelli E., Das M.P., Howard E.D., Weiner H.L., Sobel R.A., Kuchroo V.K. IL-10 is critical in the regulation of autoimmune encephalomyelitis as demonstrated by studies of IL-10- and IL-4-deficient and transgenic mice. J. Immunol. 161:1998;3299-3306.
    • (1998) J. Immunol. , vol.161 , pp. 3299-3306
    • Bettelli, E.1    Das, M.P.2    Howard, E.D.3    Weiner, H.L.4    Sobel, R.A.5    Kuchroo, V.K.6
  • 14
    • 0000038583 scopus 로고
    • Interferon-gamma mRNA expression in immediately ex-vivo CSF T cells
    • Blain M., Nalbantoglu J., Antel J. Interferon-gamma mRNA expression in immediately ex-vivo CSF T cells. J. Neuroimmunol. 54:1994;149.
    • (1994) J. Neuroimmunol. , vol.54 , pp. 149
    • Blain, M.1    Nalbantoglu, J.2    Antel, J.3
  • 15
    • 0031302405 scopus 로고    scopus 로고
    • Cell death during autoimmune demyelination: Effector but not target cells are eliminated by apoptosis
    • Bonetti B., Pohl J., Gao Y.L., Raine C.S. Cell death during autoimmune demyelination: effector but not target cells are eliminated by apoptosis. J. Immunol. 159:1997;5733-5741.
    • (1997) J. Immunol. , vol.159 , pp. 5733-5741
    • Bonetti, B.1    Pohl, J.2    Gao, Y.L.3    Raine, C.S.4
  • 17
    • 0019468319 scopus 로고
    • The effects of macrophage depletion on the clinical and pathologic expression of experimental allergic encephalomyelitis
    • Brosnan C.F., Bornstein M.B., Bloom B.R. The effects of macrophage depletion on the clinical and pathologic expression of experimental allergic encephalomyelitis. J. Immunol. 126:1981;614-620.
    • (1981) J. Immunol. , vol.126 , pp. 614-620
    • Brosnan, C.F.1    Bornstein, M.B.2    Bloom, B.R.3
  • 19
    • 0030001675 scopus 로고    scopus 로고
    • Lymphocyte homing and homeostasis
    • Butcher E.C., Picker L.J. Lymphocyte homing and homeostasis. Science. 272:1996;60-66.
    • (1996) Science , vol.272 , pp. 60-66
    • Butcher, E.C.1    Picker, L.J.2
  • 21
    • 0343181655 scopus 로고    scopus 로고
    • T-cells treated with interferon beta induce VCAM expression on brain endothelial cells: Concomitant shedding of soluble VCAM mirrors in vivo effect
    • in press
    • Calabresi, P., Prat, A., Rollins, J., Antel, J., 1999. T-cells treated with interferon beta induce VCAM expression on brain endothelial cells: Concomitant shedding of soluble VCAM mirrors in vivo effect. ECTRIMS 99, in press.
    • (1999) ECTRIMS 99
    • Calabresi, P.1    Prat, A.2    Rollins, J.3    Antel, J.4
  • 22
    • 0032193769 scopus 로고    scopus 로고
    • Steroid hormone regulation of cytokine secretion by proteolipid protein-specific CD4+ T cell clones isolated from multiple sclerosis patients and normal control subjects
    • Correale J., Arias M., Gilmore W. Steroid hormone regulation of cytokine secretion by proteolipid protein-specific CD4+ T cell clones isolated from multiple sclerosis patients and normal control subjects. J. Immunol. 161:1998;3365-3374.
    • (1998) J. Immunol. , vol.161 , pp. 3365-3374
    • Correale, J.1    Arias, M.2    Gilmore, W.3
  • 23
    • 0033559981 scopus 로고    scopus 로고
    • Transgenic interleukin 10 prevents induction of experimental autoimmune encephalomyelitis
    • Cua D.J., Groux H., Hinton D.R., Stohlman S.A., Coffman R.L. Transgenic interleukin 10 prevents induction of experimental autoimmune encephalomyelitis. J. Exp. Med. 189:1999;1005-1010.
    • (1999) J. Exp. Med. , vol.189 , pp. 1005-1010
    • Cua, D.J.1    Groux, H.2    Hinton, D.R.3    Stohlman, S.A.4    Coffman, R.L.5
  • 24
    • 0025093295 scopus 로고
    • Macrophages can modify the nonpermissive nature of the adult mammalian central nervous system
    • David S., Bouchard C., Tsatas O., Giftochristos N. Macrophages can modify the nonpermissive nature of the adult mammalian central nervous system. Neuron. 5:1990;463-469.
    • (1990) Neuron , vol.5 , pp. 463-469
    • David, S.1    Bouchard, C.2    Tsatas, O.3    Giftochristos, N.4
  • 26
    • 0021191999 scopus 로고
    • Astrocytes present myelin basic protein to encephalitogenic T-cell lines
    • Fontana A., Fierz W., Wekerle H. Astrocytes present myelin basic protein to encephalitogenic T-cell lines. Nature. 307:1984;273-276.
    • (1984) Nature , vol.307 , pp. 273-276
    • Fontana, A.1    Fierz, W.2    Wekerle, H.3
  • 27
    • 0029848128 scopus 로고    scopus 로고
    • Microglia induce CD4 T lymphocyte final effector function and death
    • Ford A.L., Foulcher E., Lemckert F.A., Sedgwick J.D. Microglia induce CD4 T lymphocyte final effector function and death. J. Exp. Med. 184:1996;1737-1745.
    • (1996) J. Exp. Med. , vol.184 , pp. 1737-1745
    • Ford, A.L.1    Foulcher, E.2    Lemckert, F.A.3    Sedgwick, J.D.4
  • 28
    • 0030973661 scopus 로고    scopus 로고
    • Amelioration of relapsing experimental autoimmune encephalomyelitis with altered myelin basic protein peptides involves different cellular mechanisms
    • Gaur A., Boehme S.A., Chalmers D., Crowe P.D., Pahuja A., Ling N., Brocke S., Steinman L., Conlon P.J. Amelioration of relapsing experimental autoimmune encephalomyelitis with altered myelin basic protein peptides involves different cellular mechanisms. J. Neuroimmunol. 74:1997;149-158.
    • (1997) J. Neuroimmunol. , vol.74 , pp. 149-158
    • Gaur, A.1    Boehme, S.A.2    Chalmers, D.3    Crowe, P.D.4    Pahuja, A.5    Ling, N.6    Brocke, S.7    Steinman, L.8    Conlon, P.J.9
  • 29
    • 0032950794 scopus 로고    scopus 로고
    • Identification of autoantibodies associated with myelin damage in multiple sclerosis
    • Genain C.P., Cannella B., Hauser S.L., Raine C.S. Identification of autoantibodies associated with myelin damage in multiple sclerosis. Nat. Med. 5:1999;170-175.
    • (1999) Nat. Med. , vol.5 , pp. 170-175
    • Genain, C.P.1    Cannella, B.2    Hauser, S.L.3    Raine, C.S.4
  • 30
    • 0342746993 scopus 로고    scopus 로고
    • Microglia/macrophages are the major source of tumour necrosis factor in permanent middle cerebral artery occlusion (pMCAO) in mice
    • in press
    • Gregersen, R., Lambertsen, K., Finsen, B., 1999. Microglia/macrophages are the major source of tumour necrosis factor in permanent middle cerebral artery occlusion (pMCAO) in mice. J. Cereb. Blood Flow Metab., in press.
    • (1999) J. Cereb. Blood Flow Metab.
    • Gregersen, R.1    Lambertsen, K.2    Finsen, B.3
  • 31
    • 0031148953 scopus 로고    scopus 로고
    • Glutamate metabolism is down-regulated in astrocytes during experimental allergic encephalomyelitis
    • Hardin-Pouzet H., Krakowski M., Bourbonniere L., Didier-Bazes M., Tran E., Owens T. Glutamate metabolism is down-regulated in astrocytes during experimental allergic encephalomyelitis. Glia. 20:1997;79-85.
    • (1997) Glia , vol.20 , pp. 79-85
    • Hardin-Pouzet, H.1    Krakowski, M.2    Bourbonniere, L.3    Didier-Bazes, M.4    Tran, E.5    Owens, T.6
  • 32
    • 0028792323 scopus 로고
    • CNS antigen presentation
    • Hart M.N., Fabry Z. CNS antigen presentation. Trends Neurosci. 18:1995;475-481.
    • (1995) Trends Neurosci. , vol.18 , pp. 475-481
    • Hart, M.N.1    Fabry, Z.2
  • 33
    • 0029743819 scopus 로고    scopus 로고
    • Cytokine phenotype of human autoreactive T cell clones specific for the immunodominant myelin basic protein peptide (83-99)
    • Hemmer B., Vergelli M., Calabresi P., Huang T., McFarland H.F., Martin R. Cytokine phenotype of human autoreactive T cell clones specific for the immunodominant myelin basic protein peptide (83-99). J. Neurosci. Res. 45:1996;852-862.
    • (1996) J. Neurosci. Res. , vol.45 , pp. 852-862
    • Hemmer, B.1    Vergelli, M.2    Calabresi, P.3    Huang, T.4    McFarland, H.F.5    Martin, R.6
  • 34
    • 0030844435 scopus 로고    scopus 로고
    • Cytokine profile of myelin basic protein-reactive T cells in multiple sclerosis and healthy individuals
    • Hermans G., Stinissen P., Hauben L., Berg-Loonen E., Raus J., Zhang J. Cytokine profile of myelin basic protein-reactive T cells in multiple sclerosis and healthy individuals. Ann. Neurol. 42:1997;18-27.
    • (1997) Ann. Neurol. , vol.42 , pp. 18-27
    • Hermans, G.1    Stinissen, P.2    Hauben, L.3    Berg-Loonen, E.4    Raus, J.5    Zhang, J.6
  • 35
    • 0025981021 scopus 로고
    • T-lymphocyte entry into the central nervous system
    • Hickey W.F., Hsu B.L., Kimura H. T-lymphocyte entry into the central nervous system. J. Neurosci. Res. 28:1991;254-260.
    • (1991) J. Neurosci. Res. , vol.28 , pp. 254-260
    • Hickey, W.F.1    Hsu, B.L.2    Kimura, H.3
  • 36
    • 0025015655 scopus 로고
    • Suppression of experimental allergic encephalomyelitis in Lewis rats after elimination of macrophages
    • Huitinga I., van Rooijen N., De Groot C.J., Uitdehaag B.M., Dijkstra C.D. Suppression of experimental allergic encephalomyelitis in Lewis rats after elimination of macrophages. J. Exp. Med. 172:1990;1025-1033.
    • (1990) J. Exp. Med. , vol.172 , pp. 1025-1033
    • Huitinga, I.1    Van Rooijen, N.2    De Groot, C.J.3    Uitdehaag, B.M.4    Dijkstra, C.D.5
  • 37
    • 0026723793 scopus 로고
    • Preferential increase of IL-2R+ CD4+ T cells and CD45RB-CD4+ T cells in the central nervous system in esperimental allergic encephalomyelitis
    • Jensen M.A., Arnason B.G., Toscas A., Noronha A. Preferential increase of IL-2R+ CD4+ T cells and CD45RB-CD4+ T cells in the central nervous system in esperimental allergic encephalomyelitis. J. Neuroimmunol. 38:1992;255-261.
    • (1992) J. Neuroimmunol. , vol.38 , pp. 255-261
    • Jensen, M.A.1    Arnason, B.G.2    Toscas, A.3    Noronha, A.4
  • 38
    • 0026707402 scopus 로고
    • Analysis of cytokine mRNA expression in the central nervous system of mice with experimental autoimmune encephalomyelitis reveals that IL-10 mRNA expression correlates with recovery
    • Kennedy M.K., Torrance D.S., Picha K.S., Mohler K.M. Analysis of cytokine mRNA expression in the central nervous system of mice with experimental autoimmune encephalomyelitis reveals that IL-10 mRNA expression correlates with recovery. J. Immunol. 149:1992;2496-2505.
    • (1992) J. Immunol. , vol.149 , pp. 2496-2505
    • Kennedy, M.K.1    Torrance, D.S.2    Picha, K.S.3    Mohler, K.M.4
  • 40
    • 0026713026 scopus 로고
    • Oral tolerance to myelin basic protein and natural recovery from experimental autoimmune encephalomyelitis are associated with downregulation of inflammatory cytokines and differential upregulation of transforming growth factor beta, interleukin 4, and prostaglandin E expression in the brain
    • Khoury S.J., Hancock W.W., Weiner H.L. Oral tolerance to myelin basic protein and natural recovery from experimental autoimmune encephalomyelitis are associated with downregulation of inflammatory cytokines and differential upregulation of transforming growth factor beta, interleukin 4, and prostaglandin E expression in the brain. J. Exp. Med. 176:1992;1355-1364.
    • (1992) J. Exp. Med. , vol.176 , pp. 1355-1364
    • Khoury, S.J.1    Hancock, W.W.2    Weiner, H.L.3
  • 41
    • 0029957071 scopus 로고    scopus 로고
    • Interferon-gamma confers resistance to experimental allergic encephalomyelitis
    • Krakowski M., Owens T. Interferon-gamma confers resistance to experimental allergic encephalomyelitis. Eur. J. Immunol. 26:1996;1641-1646.
    • (1996) Eur. J. Immunol. , vol.26 , pp. 1641-1646
    • Krakowski, M.1    Owens, T.2
  • 42
    • 0030723360 scopus 로고    scopus 로고
    • The central nervous system environment controls effector CD4+ T cell cytokine profile in experimental allergic encephalomyelitis
    • Krakowski M.L., Owens T. The central nervous system environment controls effector CD4+ T cell cytokine profile in experimental allergic encephalomyelitis. Eur. J. Immunol. 27:1997;2840-2847.
    • (1997) Eur. J. Immunol. , vol.27 , pp. 2840-2847
    • Krakowski, M.L.1    Owens, T.2
  • 43
    • 0027964523 scopus 로고
    • A single TCR antagonist peptide inhibits experimental allergic encephalomyelitis mediated by a diverse T cell repertoire
    • Kuchroo V.K., Greer J.M., Kaul D., Ishioka G., Franco A., Sette A., Sobel R.A., Lees M.B. A single TCR antagonist peptide inhibits experimental allergic encephalomyelitis mediated by a diverse T cell repertoire. J. Immunol. 153:1994;3326-3336.
    • (1994) J. Immunol. , vol.153 , pp. 3326-3336
    • Kuchroo, V.K.1    Greer, J.M.2    Kaul, D.3    Ishioka, G.4    Franco, A.5    Sette, A.6    Sobel, R.A.7    Lees, M.B.8
  • 44
    • 0030739650 scopus 로고    scopus 로고
    • Myelin basic protein-specific T helper 2 (Th2) cells cause experimental autoimmune encephalomyelitis in immunodeficient hosts rather than protect them from the disease
    • Lafaille J.J., Keere F.V., Hsu A.L., Baron J.L., Haas W., Raine C.S., Tonegawa S. Myelin basic protein-specific T helper 2 (Th2) cells cause experimental autoimmune encephalomyelitis in immunodeficient hosts rather than protect them from the disease. J. Exp. Med. 186:1997;307-312.
    • (1997) J. Exp. Med. , vol.186 , pp. 307-312
    • Lafaille, J.J.1    Keere, F.V.2    Hsu, A.L.3    Baron, J.L.4    Haas, W.5    Raine, C.S.6    Tonegawa, S.7
  • 46
    • 0030056764 scopus 로고    scopus 로고
    • Distinct patterns of multiple sclerosis pathology indicates heterogeneity on pathogenesis
    • Lucchinetti C.F., Bruck W., Rodriguez M., Lassmann H. Distinct patterns of multiple sclerosis pathology indicates heterogeneity on pathogenesis. Brain Pathol. 6:1996;259-274.
    • (1996) Brain Pathol. , vol.6 , pp. 259-274
    • Lucchinetti, C.F.1    Bruck, W.2    Rodriguez, M.3    Lassmann, H.4
  • 47
    • 0032526423 scopus 로고    scopus 로고
    • Beta-Amyloid fibrils activate parallel mitogen-activated protein kinase pathways in microglia and THP1 monocytes
    • McDonald D.R., Bamberger M.E., Combs C.K., Landreth G.E. Beta-Amyloid fibrils activate parallel mitogen-activated protein kinase pathways in microglia and THP1 monocytes. J. Neurosci. 18:1998;4451-4460.
    • (1998) J. Neurosci. , vol.18 , pp. 4451-4460
    • McDonald, D.R.1    Bamberger, M.E.2    Combs, C.K.3    Landreth, G.E.4
  • 48
    • 0343990850 scopus 로고    scopus 로고
    • Analysis of B7-1 and B7-2 costimulatory ligands in cultured mouse microglia: Upregulation by interferon-gamma and lipopolysaccharide and downregulation by interleukin-10, prostaglandin E2 and cyclic AMP-elevating agents
    • Menendez I.B., Cerase J., Ceracchini C., Levi G., Aloisi F. Analysis of B7-1 and B7-2 costimulatory ligands in cultured mouse microglia: upregulation by interferon-gamma and lipopolysaccharide and downregulation by interleukin-10, prostaglandin E2 and cyclic AMP-elevating agents. J. Neuroimmunol. 72:1997;83-93.
    • (1997) J. Neuroimmunol. , vol.72 , pp. 83-93
    • Menendez, I.B.1    Cerase, J.2    Ceracchini, C.3    Levi, G.4    Aloisi, F.5
  • 49
    • 0033049143 scopus 로고    scopus 로고
    • Autoimmune T cells protect neurons from secondary degeneration after central nervous system axotomy
    • Moalem G., Leibowitz-Amit R., Yoles E., Mor F., Cohen I.R., Schwartz M. Autoimmune T cells protect neurons from secondary degeneration after central nervous system axotomy. Nat. Med. 5:1999;49-55.
    • (1999) Nat. Med. , vol.5 , pp. 49-55
    • Moalem, G.1    Leibowitz-Amit, R.2    Yoles, E.3    Mor, F.4    Cohen, I.R.5    Schwartz, M.6
  • 50
    • 0030862594 scopus 로고    scopus 로고
    • IL-4 abrogates the inhibitory effect of IL-10 on the development of experimental allergic encephalomyelitis in SJL mice
    • Nagelkerken L., Blauw B., Tielemans M. IL-4 abrogates the inhibitory effect of IL-10 on the development of experimental allergic encephalomyelitis in SJL mice. Int. Immunol. 9:1997;1243-1251.
    • (1997) Int. Immunol. , vol.9 , pp. 1243-1251
    • Nagelkerken, L.1    Blauw, B.2    Tielemans, M.3
  • 51
    • 0031005797 scopus 로고    scopus 로고
    • TNF-alpha pretreatment induces protective effects against focal cerebral ischemia in mice
    • Nawashiro H., Tasaki K., Ruetzler C.A., Hallenbeck J.M. TNF-alpha pretreatment induces protective effects against focal cerebral ischemia in mice. J. Cereb. Blood Flow Metab. 17:1997;483-490.
    • (1997) J. Cereb. Blood Flow Metab. , vol.17 , pp. 483-490
    • Nawashiro, H.1    Tasaki, K.2    Ruetzler, C.A.3    Hallenbeck, J.M.4
  • 52
    • 0031568084 scopus 로고    scopus 로고
    • IFN-gamma-activated primary murine astrocytes express B7 costimulatory molecules and prime naive antigen-specific T cells
    • Nikcevich K.M., Gordon K.B., Tan L., Hurst S.D., Kroepfl J.F., Gardinier M., Barrett T.A., Miller S.D. IFN-gamma-activated primary murine astrocytes express B7 costimulatory molecules and prime naive antigen-specific T cells. J. Immunol. 158:1997;614-621.
    • (1997) J. Immunol. , vol.158 , pp. 614-621
    • Nikcevich, K.M.1    Gordon, K.B.2    Tan, L.3    Hurst, S.D.4    Kroepfl, J.F.5    Gardinier, M.6    Barrett, T.A.7    Miller, S.D.8
  • 53
    • 0028088924 scopus 로고
    • Astrocytes and catalase prevent the toxicity of catecholamines to oligodendrocytes
    • Noble P.G., Antel J.P., Yong V.W. Astrocytes and catalase prevent the toxicity of catecholamines to oligodendrocytes. Brain Res. 633:1994;83-90.
    • (1994) Brain Res. , vol.633 , pp. 83-90
    • Noble, P.G.1    Antel, J.P.2    Yong, V.W.3
  • 54
    • 0032033419 scopus 로고    scopus 로고
    • Cytokines induce the development of functionally heterogeneous T helper cell subsets
    • O'Garra A. Cytokines induce the development of functionally heterogeneous T helper cell subsets. Immunity. 8:1998;275-283.
    • (1998) Immunity , vol.8 , pp. 275-283
    • O'Garra, A.1
  • 55
    • 9544231789 scopus 로고    scopus 로고
    • Astrocytes promote process outgrowth by adult human oligodendrocytes in vitro through interaction between bFGF and astrocyte extracellular matrix
    • Oh L.Y., Yong V.W. Astrocytes promote process outgrowth by adult human oligodendrocytes in vitro through interaction between bFGF and astrocyte extracellular matrix. Glia. 17:1996;237-253.
    • (1996) Glia , vol.17 , pp. 237-253
    • Oh, L.Y.1    Yong, V.W.2
  • 56
    • 43949160470 scopus 로고
    • Inflammatory cytokines in the brain: Does the CNS shape immune responses?
    • Owens T., Renno T., Taupin V., Krakowski M. Inflammatory cytokines in the brain: does the CNS shape immune responses? Immunol. Today. 15:1994;566-571.
    • (1994) Immunol. Today , vol.15 , pp. 566-571
    • Owens, T.1    Renno, T.2    Taupin, V.3    Krakowski, M.4
  • 57
    • 0032209150 scopus 로고    scopus 로고
    • Immune cell entry to the CNS - A focus for immunoregulation of EAE
    • Owens T., Tran E., Hassan-Zahraee M., Krakowski M. Immune cell entry to the CNS - a focus for immunoregulation of EAE. Res. Immunol. 149:1998;781-789.
    • (1998) Res. Immunol. , vol.149 , pp. 781-789
    • Owens, T.1    Tran, E.2    Hassan-Zahraee, M.3    Krakowski, M.4
  • 58
    • 0027245888 scopus 로고
    • Macrophages and inflammation in the central nervous system
    • Perry V.H., Andersson P.B., Gordon S. Macrophages and inflammation in the central nervous system. Trends Neurosci. 16:1993;268-273.
    • (1993) Trends Neurosci. , vol.16 , pp. 268-273
    • Perry, V.H.1    Andersson, P.B.2    Gordon, S.3
  • 59
    • 0030864154 scopus 로고    scopus 로고
    • Interferon-beta interferes with the proliferation but not with the cytokine secretion of myelin basic protein-specific, T-helper type 1 lymphocytes
    • Pette M., Pette D.F., Muraro P.A., Farnon E., Martin R., McFarland H.F. Interferon-beta interferes with the proliferation but not with the cytokine secretion of myelin basic protein-specific, T-helper type 1 lymphocytes. Neurology. 49:1997;385-392.
    • (1997) Neurology , vol.49 , pp. 385-392
    • Pette, M.1    Pette, D.F.2    Muraro, P.A.3    Farnon, E.4    Martin, R.5    McFarland, H.F.6
  • 61
    • 0006462847 scopus 로고    scopus 로고
    • Induction of B7.1 and B7.2 Co-stimulatory molecule on the surface of human brain endothelial cells
    • Prat A., Becher B., Blain M., Antel J. Induction of B7.1 and B7.2 Co-stimulatory molecule on the surface of human brain endothelial cells. J. Neuroimmunol. 90:1998;24-24.
    • (1998) J. Neuroimmunol. , vol.90 , pp. 24-24
    • Prat, A.1    Becher, B.2    Blain, M.3    Antel, J.4
  • 62
    • 0032838096 scopus 로고    scopus 로고
    • Lymphocyte migration and multiple sclerosis: Relation with disease course and therapy
    • In Process Citation
    • Prat A., Al Asmi A., Duquette P., Antel J.P. Lymphocyte migration and multiple sclerosis: relation with disease course and therapy. Ann. Neurol. 46:1999;253-256. In Process Citation.
    • (1999) Ann. Neurol. , vol.46 , pp. 253-256
    • Prat, A.1    Al Asmi, A.2    Duquette, P.3    Antel, J.P.4
  • 64
    • 0032146068 scopus 로고    scopus 로고
    • Immune surveillance in the injured nervous system: T-lymphocytes invade the axotomized mouse facial motor nucleus and aggregate around sites of neuronal degeneration
    • Raivich G., Jones L.L., Kloss C.U., Werner A., Neumann H., Kreutzberg G.W. Immune surveillance in the injured nervous system: T-lymphocytes invade the axotomized mouse facial motor nucleus and aggregate around sites of neuronal degeneration. J. Neurosci. 18:1998;5804-5816.
    • (1998) J. Neurosci. , vol.18 , pp. 5804-5816
    • Raivich, G.1    Jones, L.L.2    Kloss, C.U.3    Werner, A.4    Neumann, H.5    Kreutzberg, G.W.6
  • 65
    • 0030669840 scopus 로고    scopus 로고
    • Chemokines in neurological disease models: Correlation between chemokine expression patterns and inflammatory pathology
    • Ransohoff R.M. Chemokines in neurological disease models: correlation between chemokine expression patterns and inflammatory pathology. J. Leukocyte Biol. 62:1997;645-652.
    • (1997) J. Leukocyte Biol. , vol.62 , pp. 645-652
    • Ransohoff, R.M.1
  • 66
    • 77956981608 scopus 로고
    • Selective enrichment of Th1 CD45RBlow CD4+ T cells in autoimmune infiltrates in experimental allergic encephalomyelitis
    • Renno T., Zeine R., Girard J.M., Gillani S., Dodelet V., Owens T. Selective enrichment of Th1 CD45RBlow CD4+ T cells in autoimmune infiltrates in experimental allergic encephalomyelitis. Int. Immunol. 6:1994;347-354.
    • (1994) Int. Immunol. , vol.6 , pp. 347-354
    • Renno, T.1    Zeine, R.2    Girard, J.M.3    Gillani, S.4    Dodelet, V.5    Owens, T.6
  • 67
    • 0028288512 scopus 로고
    • Cytokine production by cells in cerebrospinal fluid during experimental allergic encephalomyelitis in SJL/J mice
    • Renno T., Lin J.Y., Piccirillo C., Antel J., Owens T. Cytokine production by cells in cerebrospinal fluid during experimental allergic encephalomyelitis in SJL/J mice. J. Neuroimmunol. 49:1994;1-7.
    • (1994) J. Neuroimmunol. , vol.49 , pp. 1-7
    • Renno, T.1    Lin, J.Y.2    Piccirillo, C.3    Antel, J.4    Owens, T.5
  • 68
    • 0028983573 scopus 로고
    • TNF-alpha expression by resident microglia and infiltrating leukocytes in the central nervous system of mice with experimental allergic encephalomyelitis. Regulation by Th1 cytokines
    • Renno T., Krakowski M., Piccirillo C., Lin J.Y., Owens T. TNF-alpha expression by resident microglia and infiltrating leukocytes in the central nervous system of mice with experimental allergic encephalomyelitis. Regulation by Th1 cytokines. J. Immunol. 154:1995;944-953.
    • (1995) J. Immunol. , vol.154 , pp. 944-953
    • Renno, T.1    Krakowski, M.2    Piccirillo, C.3    Lin, J.Y.4    Owens, T.5
  • 70
    • 34547907306 scopus 로고
    • Observations on attempts to produce acute disseminated encephalomyelitis in monkeys
    • Rivers T., Sprunt D., Berry G. Observations on attempts to produce acute disseminated encephalomyelitis in monkeys. J. Exp. Med. 58:1933;39-53.
    • (1933) J. Exp. Med. , vol.58 , pp. 39-53
    • Rivers, T.1    Sprunt, D.2    Berry, G.3
  • 71
    • 0027534860 scopus 로고
    • Dissociation of antigen-presenting capacity of astrocytes for peptide-antigens versus superantigens
    • Rott O., Tontsch U., Fleischer B. Dissociation of antigen-presenting capacity of astrocytes for peptide-antigens versus superantigens. J. Immunol. 150:1993;87-95.
    • (1993) J. Immunol. , vol.150 , pp. 87-95
    • Rott, O.1    Tontsch, U.2    Fleischer, B.3
  • 72
    • 0031764104 scopus 로고    scopus 로고
    • Chemokines and chemokine receptors in T-cell priming and Th1/Th2-mediated responses
    • Sallusto F., Lanzavecchia A., Mackay C.R. Chemokines and chemokine receptors in T-cell priming and Th1/Th2-mediated responses. Immunol. Today. 19:1998;568-574.
    • (1998) Immunol. Today , vol.19 , pp. 568-574
    • Sallusto, F.1    Lanzavecchia, A.2    Mackay, C.R.3
  • 73
    • 0027773017 scopus 로고
    • Apoptosis of T lymphocytes in experimental autoimmune encephalomyelitis. Evidence for programmed cell death as a mechanism to control inflammation in the brain
    • Schmied M., Breitschopf H., Gold R., Zischler H., Rothe G., Wekerle H., Lassmann H. Apoptosis of T lymphocytes in experimental autoimmune encephalomyelitis. Evidence for programmed cell death as a mechanism to control inflammation in the brain. Am. J. Pathol. 143:1993;446-452.
    • (1993) Am. J. Pathol. , vol.143 , pp. 446-452
    • Schmied, M.1    Breitschopf, H.2    Gold, R.3    Zischler, H.4    Rothe, G.5    Wekerle, H.6    Lassmann, H.7
  • 74
  • 75
    • 0027447712 scopus 로고
    • Resident macrophages (ramified microglia) of the adult brown Norway rat central nervous system are constitutively major histocompatibility complex class II positive
    • Sedgwick J.D., Schwender S., Gregersen R., Dorries R., ter Meulen V. Resident macrophages (ramified microglia) of the adult brown Norway rat central nervous system are constitutively major histocompatibility complex class II positive. J. Exp. Med. 177:1993;1145-1152.
    • (1993) J. Exp. Med. , vol.177 , pp. 1145-1152
    • Sedgwick, J.D.1    Schwender, S.2    Gregersen, R.3    Dorries, R.4    Ter Meulen, V.5
  • 76
    • 0032536447 scopus 로고    scopus 로고
    • An interleukin (IL)-10/IL-12 immunoregulatory circuit controls susceptibility to autoimmune disease
    • Segal B.M., Dwyer B.K., Shevach E.M. An interleukin (IL)-10/IL-12 immunoregulatory circuit controls susceptibility to autoimmune disease. J. Exp. Med. 187:1998;537-546.
    • (1998) J. Exp. Med. , vol.187 , pp. 537-546
    • Segal, B.M.1    Dwyer, B.K.2    Shevach, E.M.3
  • 77
    • 0031656782 scopus 로고    scopus 로고
    • Late-onset chronic inflammatory encephalopathy in immune-competent and severe combined immune-deficient (SCID) mice with astrocyte-targeted expression of tumor necrosis factor
    • Stalder A.K., Carson M.J., Pagenstecher A., Asensio V.C., Kincaid C., Benedict M., Powell H.C., Masliah E., Campbell I.L. Late-onset chronic inflammatory encephalopathy in immune-competent and severe combined immune-deficient (SCID) mice with astrocyte-targeted expression of tumor necrosis factor. Am. J. Pathol. 153:1998;767-783.
    • (1998) Am. J. Pathol. , vol.153 , pp. 767-783
    • Stalder, A.K.1    Carson, M.J.2    Pagenstecher, A.3    Asensio, V.C.4    Kincaid, C.5    Benedict, M.6    Powell, H.C.7    Masliah, E.8    Campbell, I.L.9
  • 78
    • 0343181643 scopus 로고    scopus 로고
    • Double-blind, randomized, placebo-control, parallel-group evaluation of the safety and effect on immunologic parameters of the altered peptide ligand MSP771 in patients with MS
    • in press
    • Stark, S., Alexandria, V., Lindsey, J., Oger, J., Lublin, F., Antel, J., Sanielevici, M., Bourgouin, P., Evans, A., Crowe, P., Murphy, D., 1999. Double-blind, randomized, placebo-control, parallel-group evaluation of the safety and effect on immunologic parameters of the altered peptide ligand MSP771 in patients with MS. ECTRIMS, in press.
    • (1999) ECTRIMS
    • Stark, S.1    Alexandria, V.2    Lindsey, J.3    Oger, J.4    Lublin, F.5    Antel, J.6    Sanielevici, M.7    Bourgouin, P.8    Evans, A.9    Crowe, P.10    Murphy, D.11
  • 79
    • 0033526055 scopus 로고    scopus 로고
    • Absence of "original antigenic sin" in autoimmunity provides an unforeseen platform for immune therapy
    • Steinman L. Absence of "original antigenic sin" in autoimmunity provides an unforeseen platform for immune therapy. J. Exp. Med. 189:1999;1021-1024.
    • (1999) J. Exp. Med. , vol.189 , pp. 1021-1024
    • Steinman, L.1
  • 80
    • 0031003444 scopus 로고    scopus 로고
    • Increased severity of experimental autoimmune encephalomyelitis, chronic macrophage/microglial reactivity, and demyelination in transgenic mice producing tumor necrosis factor-alpha in the central nervous system
    • Taupin V., Renno T., Bourbonniere L., Peterson A.C., Rodriguez M., Owens T. Increased severity of experimental autoimmune encephalomyelitis, chronic macrophage/microglial reactivity, and demyelination in transgenic mice producing tumor necrosis factor-alpha in the central nervous system. Eur. J. Immunol. 27:1997;905-913.
    • (1997) Eur. J. Immunol. , vol.27 , pp. 905-913
    • Taupin, V.1    Renno, T.2    Bourbonniere, L.3    Peterson, A.C.4    Rodriguez, M.5    Owens, T.6
  • 81
    • 0030890185 scopus 로고    scopus 로고
    • Astrocytes and microglia express inducible nitric oxide synthase in mice with experimental allergic encephalomyelitis
    • Tran E.H., Hardin-Pouzet H., Verge G., Owens T. Astrocytes and microglia express inducible nitric oxide synthase in mice with experimental allergic encephalomyelitis. J. Neuroimmunol. 74:1997;121-129.
    • (1997) J. Neuroimmunol. , vol.74 , pp. 121-129
    • Tran, E.H.1    Hardin-Pouzet, H.2    Verge, G.3    Owens, T.4
  • 82
    • 0032193213 scopus 로고    scopus 로고
    • Immune invasion of the central nervous system parenchyma and experimental allergic encephalomyelitis, but not leukocyte extravasation from blood, are prevented in macrophage-depleted mice
    • Tran E.H., Hoekstra K., van Rooijen N., Dijkstra C.D., Owens T. Immune invasion of the central nervous system parenchyma and experimental allergic encephalomyelitis, but not leukocyte extravasation from blood, are prevented in macrophage-depleted mice. J. Immunol. 161:1998;3767-3775.
    • (1998) J. Immunol. , vol.161 , pp. 3767-3775
    • Tran, E.H.1    Hoekstra, K.2    Van Rooijen, N.3    Dijkstra, C.D.4    Owens, T.5
  • 83
    • 0033526109 scopus 로고    scopus 로고
    • Spontaneous regression of primary autoreactivity during chronic progression of experimental autoimmune encephalomyelitis and multiple sclerosis
    • Tuohy V.K., Yu M., Yin L., Kawczak J.A., Kinkel R.P. Spontaneous regression of primary autoreactivity during chronic progression of experimental autoimmune encephalomyelitis and multiple sclerosis. J. Exp. Med. 189:1999;1033-1042.
    • (1999) J. Exp. Med. , vol.189 , pp. 1033-1042
    • Tuohy, V.K.1    Yu, M.2    Yin, L.3    Kawczak, J.A.4    Kinkel, R.P.5
  • 84
    • 0030781925 scopus 로고    scopus 로고
    • PK11195 binding to the peripheral benzodiazepine receptor as a marker of microglia activation in multiple sclerosis and experimental autoimmune encephalomyelitis
    • Vowinckel E., Reutens D., Becher B., Verge G., Evans A., Owens T., Antel J.P. PK11195 binding to the peripheral benzodiazepine receptor as a marker of microglia activation in multiple sclerosis and experimental autoimmune encephalomyelitis. J. Neurosci. Res. 50:1997;345-353.
    • (1997) J. Neurosci. Res. , vol.50 , pp. 345-353
    • Vowinckel, E.1    Reutens, D.2    Becher, B.3    Verge, G.4    Evans, A.5    Owens, T.6    Antel, J.P.7
  • 85
    • 0027373857 scopus 로고
    • Lymphokine mRNA expression in the spinal cords of Lewis rats with experimental autoimmune encephalomyelitis is associated with a host recruited CD45R hi/CD4+ population during recovery
    • Weinberg A.D., Wyrick G., Celnik B., Vainiene M., Bakke A., Offner H., Vandenbark A.A. Lymphokine mRNA expression in the spinal cords of Lewis rats with experimental autoimmune encephalomyelitis is associated with a host recruited CD45R hi/CD4+ population during recovery. J. Neuroimmunol. 48:1993;105-117.
    • (1993) J. Neuroimmunol. , vol.48 , pp. 105-117
    • Weinberg, A.D.1    Wyrick, G.2    Celnik, B.3    Vainiene, M.4    Bakke, A.5    Offner, H.6    Vandenbark, A.A.7
  • 86
    • 0033616658 scopus 로고    scopus 로고
    • Oral tolerance with copolymer 1 for the treatment of multiple sclerosis
    • Weiner H.L. Oral tolerance with copolymer 1 for the treatment of multiple sclerosis. Proc. Nat. Acad. Sci. U.S.A. 96:1999;3333-3335.
    • (1999) Proc. Nat. Acad. Sci. U.S.A. , vol.96 , pp. 3333-3335
    • Weiner, H.L.1
  • 87
    • 0031849213 scopus 로고    scopus 로고
    • The viral triggering of autoimmune disease
    • Wekerle H. The viral triggering of autoimmune disease. Nat. Med. 4:1998;770-771.
    • (1998) Nat. Med. , vol.4 , pp. 770-771
    • Wekerle, H.1
  • 89
    • 0032005153 scopus 로고    scopus 로고
    • The roles of Fas, Fas ligand and Bcl-2 in T cell apoptosis in the central nervous system in experimental autoimmune encephalomyelitis
    • White C.A., McCombe P.A., Pender M.P. The roles of Fas, Fas ligand and Bcl-2 in T cell apoptosis in the central nervous system in experimental autoimmune encephalomyelitis. J. Neuroimmunol. 82:1998;47-55.
    • (1998) J. Neuroimmunol. , vol.82 , pp. 47-55
    • White, C.A.1    McCombe, P.A.2    Pender, M.P.3
  • 90
    • 0030587910 scopus 로고    scopus 로고
    • IFN-gamma plays a critical down-regulatory role in the induction and effector phase of myelin oligodendrocyte glycoprotein-induced autoimmune encephalomyelitis
    • Willenborg D.O., Fordham S., Bernard C.C., Cowden W.B., Ramshaw I.A. IFN-gamma plays a critical down-regulatory role in the induction and effector phase of myelin oligodendrocyte glycoprotein-induced autoimmune encephalomyelitis. J. Immunol. 157:1996;3223-3227.
    • (1996) J. Immunol. , vol.157 , pp. 3223-3227
    • Willenborg, D.O.1    Fordham, S.2    Bernard, C.C.3    Cowden, W.B.4    Ramshaw, I.A.5
  • 92
    • 0028970282 scopus 로고
    • Antigen presentation by human fetal astrocytes with the cooperative effect of microglia or the microglial-derived cytokine IL-1
    • Williams K.C., Dooley N.P., Ulvestad E., Waage A., Blain M., Yong V.W., Antel J.P. Antigen presentation by human fetal astrocytes with the cooperative effect of microglia or the microglial-derived cytokine IL-1. J. Neurosci. 15:1995;1869-1878.
    • (1995) J. Neurosci. , vol.15 , pp. 1869-1878
    • Williams, K.C.1    Dooley, N.P.2    Ulvestad, E.3    Waage, A.4    Blain, M.5    Yong, V.W.6    Antel, J.P.7
  • 94
    • 0024325672 scopus 로고
    • Antigen recognition in autoimmune encephalomyelitis and the potential for peptide-mediated immunotherapy
    • Wraith D.C., Smilek D.E., Mitchell D.J., Steinman L., McDevitt H.O. Antigen recognition in autoimmune encephalomyelitis and the potential for peptide-mediated immunotherapy. Cell. 59:1989;247-255.
    • (1989) Cell , vol.59 , pp. 247-255
    • Wraith, D.C.1    Smilek, D.E.2    Mitchell, D.J.3    Steinman, L.4    McDevitt, H.O.5
  • 95
    • 0032522119 scopus 로고    scopus 로고
    • Suppression of acute and protracted-relapsing experimental allergic encephalomyelitis by nasal administration of low-dose IL-10 in rats
    • Xiao B.G., Bai X.F., Zhang G.X., Link H. Suppression of acute and protracted-relapsing experimental allergic encephalomyelitis by nasal administration of low-dose IL-10 in rats. J. Neuroimmunol. 84:1998;230-237.
    • (1998) J. Neuroimmunol. , vol.84 , pp. 230-237
    • Xiao, B.G.1    Bai, X.F.2    Zhang, G.X.3    Link, H.4
  • 96
    • 0026630032 scopus 로고
    • Direct demonstration of the infiltration of murine central nervous system by Pgp-1/CD44high CD45RB(low) CD4+ T cells that induce experimental allergic encephalomyelitis
    • Zeine R., Owens T. Direct demonstration of the infiltration of murine central nervous system by Pgp-1/CD44high CD45RB(low) CD4+ T cells that induce experimental allergic encephalomyelitis. J. Neuroimmunol. 40:1992;57-69.
    • (1992) J. Neuroimmunol. , vol.40 , pp. 57-69
    • Zeine, R.1    Owens, T.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.