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Volumn 31, Issue 6, 1999, Pages 388-403

Obesity: An insight into its neurochemical basis and treatment

Author keywords

Energy expenditure; Energy intake; Neuropeptides; Neurotransmitters; Obesity; Treatment strategies

Indexed keywords

4 (3 TERT BUTYLAMINO 2 HYDROXYPROPOXY) 2 BENZIMIDAZOLONE; 4 [2 [[2 (3 CHLOROPHENYL) 2 HYDROXYETHYL]AMINO]PROPYL]PHENOXYACETIC ACID; 5 [2 [[2 (3 CHLOROPHENYL) 2 HYDROXYETHYL]AMINO]PROPYL] 1,3 BENZODIOXOLE 2,2 DICARBOXYLIC ACID; ALPHA INTERMEDIN; ALPRENOLOL; ANTIOBESITY AGENT; BETA 3 ADRENERGIC RECEPTOR; BUCINDOLOL; CARAZOLOL; CHOLECYSTOKININ; CORTICOTROPIN RELEASING FACTOR; DEXFENFLURAMINE; FENFLURAMINE; FLUOXETINE; GALANIN; GLUCAGON LIKE PEPTIDE 1; LEPTIN; LIPOPROTEIN LIPASE; MELANIN CONCENTRATING HORMONE; MELANOCORTIN RECEPTOR; NEUROPEPTIDE; NEUROPEPTIDE Y; NEUROTENSIN; NEUROTRANSMITTER; OXPRENOLOL; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR; SEROTONIN; TUMOR NECROSIS FACTOR ALPHA; UNCOUPLING PROTEIN; UNINDEXED DRUG;

EID: 0033376972     PISSN: 02537613     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review
Times cited : (12)

References (88)
  • 2
    • 0004090407 scopus 로고    scopus 로고
    • Geneva, Switzerland: World Health Organisation ; June 3-5
    • Consultation on obesity. Geneva, Switzerland: World Health Organisation ; June 3-5, 1997.
    • (1997) Consultation on Obesity
  • 3
  • 4
    • 0030992746 scopus 로고    scopus 로고
    • Obesity - New insights into a growing problem
    • Mason R Obesity - new insights into a growing problem. Pharmaceu J 1997;258:800-2.
    • (1997) Pharmaceu J , vol.258 , pp. 800-802
    • Mason, R.1
  • 5
    • 0039379120 scopus 로고    scopus 로고
    • Obesity
    • Bjorntop P. Obesity. Lancet 1997;350:423-6.
    • (1997) Lancet , vol.350 , pp. 423-426
    • Bjorntop, P.1
  • 6
    • 0031755436 scopus 로고    scopus 로고
    • Obesity as a chronic disease: Modern medical and lifestyle management
    • Rippe JM, Crossley S, Ringer R. Obesity as a chronic disease: Modern medical and lifestyle management. J Am Diet Assoc 1998;98:9-15
    • (1998) J Am Diet Assoc , vol.98 , pp. 9-15
    • Rippe, J.M.1    Crossley, S.2    Ringer, R.3
  • 7
    • 0030446367 scopus 로고    scopus 로고
    • Lessons from animal models of obesity
    • York YA. Lessons from animal models of obesity. Endocrin Metab Clin North Am 1996;25:781-97.
    • (1996) Endocrin Metab Clin North Am , vol.25 , pp. 781-797
    • York, Y.A.1
  • 8
    • 0026734012 scopus 로고
    • Genetic, hypothalamic and endocrine features of clinical and experimental obesity
    • Swaab, D.F., Hofman, M.A., Mirmiran, M. (Editors), Amsterdam, The Netherlands: Elsevier Science Publishers
    • Bray GA. Genetic, hypothalamic and endocrine features of clinical and experimental obesity. In: Progress in Brain Research, Swaab, D.F., Hofman, M.A., Mirmiran, M. (Editors), Amsterdam, The Netherlands: Elsevier Science Publishers 1992;93:333-41.
    • (1992) Progress in Brain Research , vol.93 , pp. 333-341
    • Bray, G.A.1
  • 10
    • 0028791036 scopus 로고
    • Energy density of diets and obesity
    • Poppitt SD. Energy density of diets and obesity. Int J Obes 1995;5:20-6.
    • (1995) Int J Obes , vol.5 , pp. 20-26
    • Poppitt, S.D.1
  • 12
    • 0018756428 scopus 로고
    • Hypothalamic and genetic obesity in experimental animals : An autocrine and endocrine hypothesis
    • Bray GA, York DA. Hypothalamic and genetic obesity in experimental animals : an autocrine and endocrine hypothesis. Physiol Rev 1979;59:719-809.
    • (1979) Physiol Rev , vol.59 , pp. 719-809
    • Bray, G.A.1    York, D.A.2
  • 13
    • 78651193167 scopus 로고
    • La différenciation sexuelle facteur déterminant des formes de l'obésité
    • Vague J. La différenciation sexuelle facteur déterminant des formes de l'obésité. Presse Med 1947;55:339-40.
    • (1947) Presse Med , vol.55 , pp. 339-340
    • Vague, J.1
  • 14
    • 0028091785 scopus 로고
    • Regional adiposity and morbidity
    • Kiessebah AH, Krakower GR. Regional adiposity and morbidity. Physiol Rev 1994;74:775-811.
    • (1994) Physiol Rev , vol.74 , pp. 775-811
    • Kiessebah, A.H.1    Krakower, G.R.2
  • 15
    • 0019943007 scopus 로고
    • Relation of body fat distribution to metabolic complications of obesity
    • Kiessebah AH, Vydelingum N, Murray R, et al. Relation of body fat distribution to metabolic complications of obesity. J Clin Endocrin Metab 1982;54:254-60.
    • (1982) J Clin Endocrin Metab , vol.54 , pp. 254-260
    • Kiessebah, A.H.1    Vydelingum, N.2    Murray, R.3
  • 18
    • 0032474246 scopus 로고    scopus 로고
    • Not all fat is alike
    • Arner P. Not all fat is alike. Lancet 1998;351:1301-2.
    • (1998) Lancet , vol.351 , pp. 1301-1302
    • Arner, P.1
  • 19
    • 0028868635 scopus 로고
    • Physiological regulation of macronutrient balance
    • Frayn KN. Physiological regulation of macronutrient balance. Int J Obes 1995;19:4-10
    • (1995) Int J Obes , vol.19 , pp. 4-10
    • Frayn, K.N.1
  • 20
    • 0023934067 scopus 로고
    • Stress: Hypothalamic functions and neuroendocrine consequences
    • Polkow B. Stress: hypothalamic functions and neuroendocrine consequences. Acta Med Scand 1988;723:61-70.
    • (1988) Acta Med Scand , vol.723 , pp. 61-70
    • Polkow, B.1
  • 21
    • 0025748673 scopus 로고
    • Metabolic implications of body fat distribution
    • Bjorntorp P. Metabolic implications of body fat distribution. Diabetes Care 1991;14:1132-43.
    • (1991) Diabetes Care , vol.14 , pp. 1132-1143
    • Bjorntorp, P.1
  • 22
    • 0022250141 scopus 로고
    • Cellular mechanism in selected states of insulin resistance: Human obesity, glucocorticoid excess and chronic renal failure
    • Amatruda JM, Livingstone JN, Lockwood DN. Cellular mechanism in selected states of insulin resistance: human obesity, glucocorticoid excess and chronic renal failure. Diabetes Metab Rev 1985;3:293-317.
    • (1985) Diabetes Metab Rev , vol.3 , pp. 293-317
    • Amatruda, J.M.1    Livingstone, J.N.2    Lockwood, D.N.3
  • 23
    • 0030763001 scopus 로고    scopus 로고
    • Obesity treatment
    • Wilding J. Obesity treatment. BMJ. 1997;315:997-1000.
    • (1997) BMJ , vol.315 , pp. 997-1000
    • Wilding, J.1
  • 24
    • 13344279395 scopus 로고    scopus 로고
    • A role for melanin concentrating hormone in the central regulation of feeding behaviour
    • Qu D, Ludwig DS. A role for melanin concentrating hormone in the central regulation of feeding behaviour. Nature 1996;380:243-7.
    • (1996) Nature , vol.380 , pp. 243-247
    • Qu, D.1    Ludwig, D.S.2
  • 25
    • 0030972558 scopus 로고    scopus 로고
    • Obesity, diabetes and functions for proopiomelanocortin-derived peptides
    • Mounjoy KG, Wong J. Obesity, diabetes and functions for proopiomelanocortin-derived peptides. Mol Cell Endocrin 1997;128:171-7.
    • (1997) Mol Cell Endocrin , vol.128 , pp. 171-177
    • Mounjoy, K.G.1    Wong, J.2
  • 26
    • 0024459484 scopus 로고
    • Melanin concentrating hormone (MCH) : Structure, function aspects of its melanocyte stimulating hormone like (MSH-like) activity
    • Matsunaga TO, Hruby VI. Melanin concentrating hormone (MCH) : Structure, function aspects of its melanocyte stimulating hormone like (MSH-like) activity. Peptides 1989;10: 773-8.
    • (1989) Peptides , vol.10 , pp. 773-778
    • Matsunaga, T.O.1    Hruby, V.I.2
  • 27
    • 0027336553 scopus 로고
    • α-MSH and MCH are functional antagonists in a central nervous system auditory gating paradigm
    • Miller CL, Hruby VI. α-MSH and MCH are functional antagonists in a central nervous system auditory gating paradigm. Ann NY Acad Sci 1993;680:571-4.
    • (1993) Ann NY Acad Sci , vol.680 , pp. 571-574
    • Miller, C.L.1    Hruby, V.I.2
  • 28
    • 0031015701 scopus 로고    scopus 로고
    • Appetite suppression by commonly used drugs depends on 5-HT availability
    • Curzon G, Gibson EL, Oluyomi AO. Appetite suppression by commonly used drugs depends on 5-HT availability. TIPS 1997;18:21-5.
    • (1997) TIPS , vol.18 , pp. 21-25
    • Curzon, G.1    Gibson, E.L.2    Oluyomi, A.O.3
  • 30
    • 0027171661 scopus 로고
    • Is cholecystokinin the peptide that controls the food intake?
    • Greenberg D. Is cholecystokinin the peptide that controls the food intake? Nutrition Review 1993;51:181-9.
    • (1993) Nutrition Review , vol.51 , pp. 181-189
    • Greenberg, D.1
  • 31
    • 0028823717 scopus 로고
    • Cholecystokinin is a satiety hormone in humans at physiological postprandial plasma-concentrations
    • Ballinger A, Mcloughlin L, Medbak S, Clark M. Cholecystokinin is a satiety hormone in humans at physiological postprandial plasma-concentrations. Clin Sci 1995;89:375-81.
    • (1995) Clin Sci , vol.89 , pp. 375-381
    • Ballinger, A.1    Mcloughlin, L.2    Medbak, S.3    Clark, M.4
  • 32
    • 0024953269 scopus 로고
    • The satiating effects of fats is attenuated by cholecystokinin antagonist-Lorglumide
    • Greenberg D, Torres NI, Smith GP, Gibbs J. The satiating effects of fats is attenuated by cholecystokinin antagonist-Lorglumide. Ann NY Acad Sci 1989;575:517-20.
    • (1989) Ann NY Acad Sci , vol.575 , pp. 517-520
    • Greenberg, D.1    Torres, N.I.2    Smith, G.P.3    Gibbs, J.4
  • 33
    • 0026560031 scopus 로고
    • CCK- receptor antagonists attenuate suppression of sham feeding by intestinal nutrients
    • Yox DP, Brenner L, Ritter RC. CCK- receptor antagonists attenuate suppression of sham feeding by intestinal nutrients. Am J Physiol 1992;262:554-61.
    • (1992) Am J Physiol , vol.262 , pp. 554-561
    • Yox, D.P.1    Brenner, L.2    Ritter, R.C.3
  • 34
    • 0024409969 scopus 로고
    • Duodenal infusion of fat, cholecystokinin secretion and satiety in the pig
    • Gregory PC, McFadyn M, Duodenal infusion of fat, cholecystokinin secretion and satiety in the pig. Physiol Behav 1989;45:1021-4.
    • (1989) Physiol Behav , vol.45 , pp. 1021-1024
    • Gregory, P.C.1    McFadyn, M.2
  • 35
    • 0344504163 scopus 로고
    • Comparative effects of cholecystokinin (CCK-A) receptor antagonist L 364718 and CCK-B antagonist L365260 on solid food intake in rats
    • Reidelberger RD, Varga G, Solomon TE. Comparative effects of cholecystokinin (CCK-A) receptor antagonist L 364718 and CCK-B antagonist L365260 on solid food intake in rats. Soc Neurosci 1990;16:978.
    • (1990) Soc Neurosci , vol.16 , pp. 978
    • Reidelberger, R.D.1    Varga, G.2    Solomon, T.E.3
  • 36
    • 0032507402 scopus 로고    scopus 로고
    • New approaches to the treatment of obesity
    • Robin G. New approaches to the treatment of obesity. Pharmaceu J 1998;260:536-7.
    • (1998) Pharmaceu J , vol.260 , pp. 536-537
    • Robin, G.1
  • 37
    • 0030889192 scopus 로고    scopus 로고
    • Targeted disruption of melanocortin-4 receptors results in obesity in mice
    • Huszar D, Lynch CA, Dunmore JH, et al. Targeted disruption of melanocortin-4 receptors results in obesity in mice. Cell 1997;88:131-41.
    • (1997) Cell , vol.88 , pp. 131-141
    • Huszar, D.1    Lynch, C.A.2    Dunmore, J.H.3
  • 38
    • 0028112970 scopus 로고
    • Agouti protein is an antagonist of the melanocyte stimulating hormone receptor
    • Lu D, Willard D, Patel IR, Kadwell S, Overton L, Kost T. Agouti protein is an antagonist of the melanocyte stimulating hormone receptor. Nature 1994;371:799-802.
    • (1994) Nature , vol.371 , pp. 799-802
    • Lu, D.1    Willard, D.2    Patel, I.R.3    Kadwell, S.4    Overton, L.5    Kost, T.6
  • 39
    • 0030061922 scopus 로고    scopus 로고
    • IRS-1 mediated inhibition of insulin receptor tyrosine kinase activity in TNF-α-and obesity induced insulin resistance
    • Hotamistigil GS, Peraldi P, Budavari A. IRS-1 mediated inhibition of insulin receptor tyrosine kinase activity in TNF-α-and obesity induced insulin resistance. Science 1996; 27:665-8.
    • (1996) Science , vol.27 , pp. 665-668
    • Hotamistigil, G.S.1    Peraldi, P.2    Budavari, A.3
  • 40
    • 0028362194 scopus 로고
    • Tumour necrosis factor alpha inhibits signalling from the insulin receptor
    • Hotamisligil GS, Murray DL, Choy LN. Tumour necrosis factor alpha inhibits signalling from the insulin receptor. Proc Natl Acad Sci 1994;91:4854-8.
    • (1994) Proc Natl Acad Sci , vol.91 , pp. 4854-4858
    • Hotamisligil, G.S.1    Murray, D.L.2    Choy, L.N.3
  • 41
    • 0028506528 scopus 로고
    • CNS and peripheral abnormalities : Clues to the understanding of obesity and NIDDM
    • Jeanrenaud B. CNS and peripheral abnormalities : clues to the understanding of obesity and NIDDM. Diabetologia 1994;37:170-8.
    • (1994) Diabetologia , vol.37 , pp. 170-178
    • Jeanrenaud, B.1
  • 42
    • 0028931724 scopus 로고
    • Increased adipose tissue expression of tumor necrosis factor alpha in human obesity and insulin resistance
    • Hotamisligil GS, Arner P, Caro JF. Increased adipose tissue expression of tumor necrosis factor alpha in human obesity and insulin resistance. J Clin Invest 1995;95:2409-15.
    • (1995) J Clin Invest , vol.95 , pp. 2409-2415
    • Hotamisligil, G.S.1    Arner, P.2    Caro, J.F.3
  • 43
    • 0028968879 scopus 로고
    • The expression of TNF factor in human adipose tissue: Regulation by obesity, weight loss and relationship to lipoprotein lipase
    • Kern PA, Saghizad M, Ong JM. The expression of TNF factor in human adipose tissue: Regulation by obesity, weight loss and relationship to lipoprotein lipase. J Clin Invest 1995;95:2111-9.
    • (1995) J Clin Invest , vol.95 , pp. 2111-2119
    • Kern, P.A.1    Saghizad, M.2    Ong, J.M.3
  • 45
    • 0030775793 scopus 로고    scopus 로고
    • Regulation of adipose tissue lipoprotein lipase in young and old rats
    • Bergö M, Olivecrona G, Olivecrona T. Regulation of adipose tissue lipoprotein lipase in young and old rats. Int J Obes 1997;21:980-6.
    • (1997) Int J Obes , vol.21 , pp. 980-986
    • Bergö, M.1    Olivecrona, G.2    Olivecrona, T.3
  • 46
    • 0030611101 scopus 로고    scopus 로고
    • Potential role of TNF - α- and lipoprotein lipase as candidate genes for obesity
    • Kern PA. Potential role of TNF - α- and lipoprotein lipase as candidate genes for obesity. J Nutr 1997; 127:1917-22.
    • (1997) J Nutr , vol.127 , pp. 1917-1922
    • Kern, P.A.1
  • 49
    • 0029978426 scopus 로고    scopus 로고
    • Nocturnal rise in leptin in lean, obese and NIDDM subjects
    • Sinha MK, Ohannesian JP, Heiman ML, et al. Nocturnal rise in leptin in lean, obese and NIDDM subjects. J Clin Invest 1996;97:1344-7.
    • (1996) J Clin Invest , vol.97 , pp. 1344-1347
    • Sinha, M.K.1    Ohannesian, J.P.2    Heiman, M.L.3
  • 50
    • 14444268971 scopus 로고    scopus 로고
    • Interaction between leptin and hypothalamic neuropeptide Y neurons in the control of food intake and energy homeostasis in the rat
    • Wang Q, Bing C, Al-Barazanji K, Mossakowaska DE, Wang X, McBay D. Interaction between leptin and hypothalamic neuropeptide Y neurons in the control of food intake and energy homeostasis in the rat. Diabetes 1997;46:335-41.
    • (1997) Diabetes , vol.46 , pp. 335-341
    • Wang, Q.1    Bing, C.2    Al-Barazanji, K.3    Mossakowaska, D.E.4    Wang, X.5    McBay, D.6
  • 51
  • 52
    • 0344450708 scopus 로고    scopus 로고
    • A mutation in the human leptin receptor gene causes obesity and pituitary dysfunction
    • Clement G. A mutation in the human leptin receptor gene causes obesity and pituitary dysfunction. Nature 1998; 392:398-404.
    • (1998) Nature , vol.392 , pp. 398-404
    • Clement, G.1
  • 53
    • 0031839019 scopus 로고    scopus 로고
    • The circadian rhythm of leptin is preserved in growth hormone deficient hypopituitary adults
    • Kausta E, Chrisoulidou A, Lawrence NJ, et al. The circadian rhythm of leptin is preserved in growth hormone deficient hypopituitary adults. Clin Endocrin 1998;48:685-90.
    • (1998) Clin Endocrin , vol.48 , pp. 685-690
    • Kausta, E.1    Chrisoulidou, A.2    Lawrence, N.J.3
  • 54
    • 0030297919 scopus 로고    scopus 로고
    • Adipogenesis and obesity: Rounding out the big picture
    • Spiegelman BM, Jeffrey SF. Adipogenesis and obesity: rounding out the big picture. Cell 1996;87:377-89.
    • (1996) Cell , vol.87 , pp. 377-389
    • Spiegelman, B.M.1    Jeffrey, S.F.2
  • 55
    • 0029566960 scopus 로고    scopus 로고
    • Advances in the understanding of molecular basis of obesity
    • Meier CA. Advances in the understanding of molecular basis of obesity. J Endocrin 1997;133:761-3.
    • (1997) J Endocrin , vol.133 , pp. 761-763
    • Meier, C.A.1
  • 57
    • 0033082426 scopus 로고    scopus 로고
    • Feeding and body-weight regulation by hypothalamic neuropeptides-mediation of actions of leptin
    • Inui A. Feeding and body-weight regulation by hypothalamic neuropeptides-mediation of actions of leptin. TINS 1999;22:62-7.
    • (1999) TINS , vol.22 , pp. 62-67
    • Inui, A.1
  • 65
    • 0021322138 scopus 로고
    • Thermogenic mechanisms in brown fat
    • Nicholas DG, Locke RM. Thermogenic mechanisms in brown fat. Physiol Rev 1984;64:1-64.
    • (1984) Physiol Rev , vol.64 , pp. 1-64
    • Nicholas, D.G.1    Locke, R.M.2
  • 66
    • 0025260137 scopus 로고
    • Brown adipose tissue thermogenesis : Interdisciplinary studies
    • Himms-Hagen J. Brown adipose tissue thermogenesis : interdisciplinary studies. FASEB J 1990;4:2890-8.
    • (1990) FASEB J , vol.4 , pp. 2890-2898
    • Himms-Hagen, J.1
  • 67
    • 0026562272 scopus 로고
    • Analysis of uncoupling proteins and its mRNA in adipose tissue deposits of adult humans
    • Garruti G, Ricquier D. Analysis of uncoupling proteins and its mRNA in adipose tissue deposits of adult humans. Int J Obes Relat Metab Disord 1992;16:283-390.
    • (1992) Int J Obes Relat Metab Disord , vol.16 , pp. 283-390
    • Garruti, G.1    Ricquier, D.2
  • 70
    • 0031560941 scopus 로고    scopus 로고
    • UCP-3 : An uncoupling protein homologue expressed preferentially and abundantly in skeletal muscle and brown adipose tissue
    • VidalPuig A, Solanes G, Flier JS, Lowell BB. UCP-3 : an uncoupling protein homologue expressed preferentially and abundantly in skeletal muscle and brown adipose tissue. Biochem Biophys Res Commun 1997;235:79-82.
    • (1997) Biochem Biophys Res Commun , vol.235 , pp. 79-82
    • VidalPuig, A.1    Solanes, G.2    Flier, J.S.3    Lowell, B.B.4
  • 71
    • 0032554394 scopus 로고    scopus 로고
    • The stubborn enigma of obesity
    • Macready N. The stubborn enigma of obesity. Lancet 1998; 351:888.
    • (1998) Lancet , vol.351 , pp. 888
    • Macready, N.1
  • 72
    • 3543076887 scopus 로고    scopus 로고
    • The role of the behavioural counsellor in obesity treatment
    • Foreyt JP, Poston CW. The role of the behavioural counsellor in obesity treatment. J Am Diet Assoc 1998;98:27-30.
    • (1998) J Am Diet Assoc , vol.98 , pp. 27-30
    • Foreyt, J.P.1    Poston, C.W.2
  • 73
    • 0031786825 scopus 로고    scopus 로고
    • A model of chronic care of obesity through dietary treatment
    • Nonas CA. A model of chronic care of obesity through dietary treatment. J Am Diet Assoc 1998;98:16-22.
    • (1998) J Am Diet Assoc , vol.98 , pp. 16-22
    • Nonas, C.A.1
  • 74
    • 0026680624 scopus 로고
    • Appetite suppressants-a review
    • Silverstone T. Appetite suppressants-a review. Drugs 1992;43:820-36.
    • (1992) Drugs , vol.43 , pp. 820-836
    • Silverstone, T.1
  • 75
    • 0027363269 scopus 로고
    • Use and abuse of appetite-suppressant drugs in the treatment of obesity
    • Bray GA. Use and abuse of appetite-suppressant drugs in the treatment of obesity. Ann Intern Med 1993;119:707-13.
    • (1993) Ann Intern Med , vol.119 , pp. 707-713
    • Bray, G.A.1
  • 76
    • 6744249381 scopus 로고    scopus 로고
    • Balancing the risks of antiobesity pills
    • Fricker J. Balancing the risks of antiobesity pills. The Lancet 1997;349-1374.
    • (1997) The Lancet , pp. 349-1374
    • Fricker, J.1
  • 77
    • 0030876952 scopus 로고    scopus 로고
    • Valvular heart disease associated with fenfluramine-phentermine
    • Connolly HM, Cray JL, McGoon MD. Valvular heart disease associated with fenfluramine-phentermine. N Eng J Med 1997;337:581-8.
    • (1997) N Eng J Med , vol.337 , pp. 581-588
    • Connolly, H.M.1    Cray, J.L.2    McGoon, M.D.3
  • 79
    • 0029399534 scopus 로고
    • Sibutramine : A novel agent for obesity treatment
    • Ryan DH, Kaiser P, Bray GA. Sibutramine : a novel agent for obesity treatment. Obes Res 1995;3:553-9.
    • (1995) Obes Res , vol.3 , pp. 553-559
    • Ryan, D.H.1    Kaiser, P.2    Bray, G.A.3
  • 80
    • 0030479510 scopus 로고    scopus 로고
    • Medicating the obese patient
    • Rxan DH. Medicating the obese patient. Endocrin Metab Clin North Am 1996;25:989-1003.
    • (1996) Endocrin Metab Clin North Am , vol.25 , pp. 989-1003
    • Rxan, D.H.1
  • 81
    • 6744231833 scopus 로고    scopus 로고
    • Newest anti-obesity drug fails to pass FDA muster
    • Adult A. Newest anti-obesity drug fails to pass FDA muster. The Lancet 1998;351:885.
    • (1998) The Lancet , vol.351 , pp. 885
    • Adult, A.1
  • 82
    • 0026523485 scopus 로고
    • The effect and safety of an ephedrine/caffeine compound compared to ephedrine, caffeine and placebo in obese subjects
    • Astrup A, Breum L, Toubro S, Hein P, Quaade R. The effect and safety of an ephedrine/caffeine compound compared to ephedrine, caffeine and placebo in obese subjects. Int J Obes 1992;16:269-77.
    • (1992) Int J Obes , vol.16 , pp. 269-277
    • Astrup, A.1    Breum, L.2    Toubro, S.3    Hein, P.4    Quaade, R.5
  • 83
    • 0027481850 scopus 로고
    • Clinical aspects of ephedrine in the treatment of obesity
    • Pasquali R, Casimirri F. Clinical aspects of ephedrine in the treatment of obesity. Int J Obes 1993;17:65-8
    • (1993) Int J Obes , vol.17 , pp. 65-68
    • Pasquali, R.1    Casimirri, F.2
  • 84
  • 85
    • 10544235698 scopus 로고    scopus 로고
    • Long-term pharmcotherapy in the management of obesity
    • Dietz WM, Goodwin NJ, Yanovski SZ. Long-term pharmcotherapy in the management of obesity. JAMA 1996;276:1907-15.
    • (1996) JAMA , vol.276 , pp. 1907-1915
    • Dietz, W.M.1    Goodwin, N.J.2    Yanovski, S.Z.3
  • 86
    • 0033083323 scopus 로고    scopus 로고
    • Neuropeptide Y feeding receptors: Are multiple subtypes involved?
    • Inui A. Neuropeptide Y feeding receptors: are multiple subtypes involved? TIPS 1999;20:43-6.
    • (1999) TIPS , vol.20 , pp. 43-46
    • Inui, A.1
  • 87
    • 0032951493 scopus 로고    scopus 로고
    • CART peptides : Therapeutic potential in obesity and feeding disorders
    • Couceyro PR, Lambert PD. CART peptides : therapeutic potential in obesity and feeding disorders. Drug News Perspect 1999;12:133-6.
    • (1999) Drug News Perspect , vol.12 , pp. 133-136
    • Couceyro, P.R.1    Lambert, P.D.2
  • 88
    • 0032971425 scopus 로고    scopus 로고
    • Orlistat for long term treatment of obesity
    • Harp JB. Orlistat for long term treatment of obesity. Drugs of Today 1999;35:139-45.
    • (1999) Drugs of Today , vol.35 , pp. 139-145
    • Harp, J.B.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.