Cellular adhesion molecules and atherogenesis

American Journal of Medicine

Volumn 107, Issue 1, 1999, Pages 85-97

  Price, Daniel T ^a   Loscalzo, Joseph ^a  

^a BOSTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ABCIXIMAB; FIBRINOGEN RECEPTOR; FIBRINOGEN RECEPTOR ANTAGONIST; HOMOCYSTEINE; INTEGRIN; LIGAND; SELECTIN;

ARTICLE; ATHEROGENESIS; ATHEROSCLEROSIS; CARDIOVASCULAR RISK; CELL ADHESION; CELL INTERACTION; DISEASE ASSOCIATION; ENDOTHELIUM INJURY; HUMAN; IMMUNOGLOBULIN GENE; INFLAMMATION; PATHOPHYSIOLOGY; PRIORITY JOURNAL; RISK FACTOR;

ARTERIOSCLEROSIS; CELL ADHESION MOLECULES; ENDOTHELIUM, VASCULAR; GENE EXPRESSION REGULATION; HUMANS; INTEGRINS; PLATELET GLYCOPROTEIN GPIIB-IIIA COMPLEX; RISK FACTORS; SELECTINS; SIGNAL TRANSDUCTION; THROMBOSIS;

EID: 0033166891     PISSN: 00029343     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0002-9343(99)00153-9     Document Type: Article

References (156)

1. Albelda S.M., Buck C.A. Integrins and other cell adhesion molecules. FASEB J. 4:1990;2868-2879.
2. Hynes R.O. Integrins versatility, modulation, and signaling in cell adhesion . Cell. 69:1992;11-26.
3. Springer T.A. Traffic signals for lymphocyte recirculation and leukocyte emigration the multistep paradigm . Cell. 76:1994;301-314.
4. Maxfield S.R., Moulder K., Koning F., et al. Murine T cells express a cell surface receptor for multiple extracellular matrix proteins. Identification and characterization with monoclonal antibodies. J Exp Med. 169:1989;2173-2190.
5. Springer T.A. Adhesion receptors of the immune system. Nature. 346:1990;425-434.
6. Muller W.A., Weigl S.A., Deng X., Phillips D.M. PECAM-1 is required for transendothelial migration of leukocytes. J Exp Med. 178:1993;449-460.
7. Albelda S.M., Oliver P.D., Romer L.H., Buck C.A. EndoCAM a novel endothelial cell-cell adhesion molecule . J Cell Biol. 110:1990;1227-1237.
8. Newman P.J., Berdnt M.C., Gorsky J., White G.C., Paddock L.S., Muller W.A. PECAM-1 (CD31) cloning and relation to adhesion molecules of the immunoglobulin gene superfamily. Science. 247:1990;1219-1222.
9. Dustin M.L., Rothlein R., Bhan A.K., Dinarello C.A., Springer T.A. Induction by IL 1 and interferon-gamma tissue distribution, biochemistry, and function of a natural adherence molecule (ICAM-1) . J Immunol. 137:1986;245-254.
10. Pober J.S., Gimbrone M.A. Jr, Lapierre L.A., et al. Overlapping patterns of activation of human endothelial cells by interleukin 1, tumor necrosis factor, and immune interferon. J Immunol. 137:1986;1893-1896.
11. Marui N., Offermann M.K., Swerlick R., et al. Vascular cell adhesion molecule-1 (VCAM-1) gene transcription and expression are regulated through an antioxidant-sensitive mechanism in human vascular endothelial cells. J Clin Invest. 92:1993;1866-1874.
12. Vaporicyan A.A., DeLisser H.M., Yan H.C., et al. Involvement of platelet-endothelial cell adhesion molecule-1 in neutrophil recruitment in vivo. Science. 262:1993;1580-1582.
13. Piali L., Hammel P., Uherek F., et al. CD31/PECAM-1 is a ligand for αvβ3 integrin involved in adhesion of leukocytes to endothelium. J Cell Biol. 130:1995;451-460.
14. Buckley C.D., Doyonnas R., Newton J.P., et al. Identification of αvβ3 as a heterotypic ligand for CD31/PECAM-1. J Cell Sci. 109:1996;437-445.
15. DeLisser H.M., Chilkotowsky J., Yan H., Daise M., Buck C.A., Albelda S.M. Deletions in the cytoplasmic domain of platelet-endothelial cell adhesion molecule-1 (PECAM-1, CD31) result in changes in ligand binding properties. J Cell Biol. 124:1994;195-203.
16. Yan H., Baldwin H.S., Sun J., Buck C.A., Albelda S.M., DeLisser H.M. Alternative splicing of a specific cytoplasmic exon alters the binding characteristics of murine platelet/endothelial cell adhesion molecule-1 (PECAM-1). J Biol Chem. 270:1995;23672-23680.
17. McEver R.P., Cummings R.D. Role of PSGL-1 binding to selectins in leukocyte recruitment. J Clin Invest. 100:1997;97S-103S.
18. McEver R.P., Moore K.L., Cummings R.D. Leukocyte trafficking mediated by selectin-carbohydrate interactions. J Biol Chem. 270:1995;11025-11028.
19. Bevilacqua M.P., Pober J.S., Wheller M.E., Cotran R.S., Gimbrone M.A.J. Interleukin 1 acts on cultured human vascular endothelium to increase the adhesion of polymorphonuclear leukocytes, monocytes, and related leukocyte cell lines. J Clin Invest. 76:1985;2003-2011.
20. McEver R.P., Beckstead J.H., Moore K.L., Marshall-Carlson L., Bainton D.F. GMP-140, a platelet alpha-granule membrane protein, is also synthesized by vascular endothelial cells and is localized in Weibel-Palade bodies. J Clin Invest. 84:1989;92-99.
21. Tedder T.F., Penta A.C., Levine H.B., Freedman A.S. Expression of the human leukocyte adhesion molecule, LAM1. Identity with the TQ1 and Leu-8 differentiation antigens. J Immunol. 144:1990;532-534.
22. Weyrich A.S., Elstad M.R., McEver R.P., et al. Activated platelets signal chemokine synthesis by human monocytes. J Clin Invest. 97:1996;1525-1534.
23. Frenette PS, Wagner DD. Adhesion molecules. NEJM 1996;334:1526-1529; 335:43-45.
24. Schlaepfer D.D., Hunter T. Integrin signalling and tyrosine phosphorylation just the FAKs? Trends Cell Biol. 8:1998;151-157.
25. Longhurst C.M., Jennings L.K. Integrin-mediated signal transduction. Cell Mol Life Sci. 54:1998;514-526.
26. Hynes R.O. Integrins versatility, modulation, and signaling in cell adhesion . Cell. 69:1992;11-26.
27. Weber C., Lu C.F., Casasnovas J.M., Springer T.A. Role of alpha L beta 2 integrin avidity in transendothelial chemotaxis of mononuclear cells. J Immunol. 159:1997;3968-3975.
28. Simon D.I., Ezratty A.M., Francis S.A., Rennke H., Loscalzo J. Fibrin(ogen) is internalized and degraded by activated human monocytoid cells via Mac-1 (CD11b/CD18) a nonplasmin fibrinolytic pathway . Blood. 82:1993;2414-2422.
29. Ross R., Glomset J.A. Atherosclerosis and the arterial smooth muscle cell proliferation of smooth muscle is a key event in the genesis of the lesions of atherosclerosis . Science. 180:1973;1332-1339.
30. Ross R, Glomset JA. The pathogenesis of atherosclerosis. NEJM 1976;295:369-377 and 420-425.
31. Ross R. The pathogenesis of atherosclerosis - an update. NEJM. 314:1986;488-500.
32. Ross R. The pathogenesis of atherosclerosis a perspective for the 1990s . Nature. 362:1993;801-809.
33. Poole J.C.F., Florey H.W. Changes in the endothelium of the aorta and the behavior of macrophages in experimental atheroma of rabbits. J Path Bact. 75:1958;245-253.
34. Gerrity R.G., Naito H.K., Richardson M., Schwartz C.J. Dietary-induced atherogenesis in swine morphology of the intima in prelesion stages . Am J Pathol. 95:1979;775-786.
35. Joris I., Zand T., Nunnari J.J., Krolikowski F.J., Majno G. Studies on the pathogenesis of atherosclerosis. I. Adhesion and emigration of mononuclear cells in the aorta of hypercholesterolemic rats. Am J Pathol. 113:1983;341-358.
36. Masuda J., Ross R. Studies of hypercholesterolemia in the nonhuman primate. I Changes that lead to fatty streak formation . Arteriosclerosis. 10:1990;164-177.
37. Masuda J., Ross R. Studies of hypercholesterolemia in the nonhuman primate. II Fatty streak conversion to fibrous plaque . Arteriosclerosis. 10:1990;178-187.
38. Stary H.C. Evolution of atherosclerotic plaques in the coronary arteries of young adults. Arteriosclerosis. 3:1983;471A.
39. Gimbrone M.A.J., Bevilacqua M.P., Cybulsky M.I. Endothelial-dependent mechanisms of leukocyte adhesion in inflammation and atherosclerosis. Ann NY Acad Sci. 598:1990;77-85.
40. Osborn L., Hession C., Tizard R., et al. Direct expression cloning of vascular cell adhesion molecule-1, a cytokine-induced endothelial protein that binds to lymphocytes. Cell. 59:1989;1203-1211.
41. Elices M.J., Osborn L., Takada Y., et al. VCAM-1 on activated endothelium interacts with the leukocyte integrin VLA-4 at a site distinct from the VLA-4/fibronectin binding site. Cell. 60:1990;577-584.
42. Cybulsky M.I., Gimbrone M.A.J. Endothelial expression of a mononuclear leukocyte adhesion molecule during atherogenesis. Science. 251:1991;788-791.
43. Li H., Cybulsky M.I., Gimbrone M.A. Jr, Libby P. An atherogenic diet rapidly induces VCAM-1, a cytokine regulatable mononuclear leukocyte adhesion molecule, in rabbit endothelium. Arterioscler Thromb. 13:1993;197-204.
44. Poston R.N., Haskard D.O., Coucher J.R., Gall N.P., Johnson-Tidey R.R. Expression of intercellular adhesion molecule-1 in atherosclerotic plaques. Am J Pathol. 140:1992;665-673.
45. Printseva O.Y.U., Peclo M.M., Gown A.M. Various cell types in human atherosclerotic lesions express ICAM-1. Further immunocytochemical and immunochemical studies employing monoclonal antibody 10F3. Am J Pathol. 140:1992;889-896.
46. O'Brien K.D., Allen M.D., McDonald T.O., et al. Vascular cell adhesion molecule-1 is expressed in human coronary atherosclerotic plaques implications for the mode of progression of advanced coronary atherosclerosis . J Clin Invest. 92:1993;945-951.
47. O'Brien K.D., McDonald T.O., Chait A., Allen M.D., Alpers C.E. Neovascular expression of E-selectin, intercellular adhesion molecule-1, and vascular cell adhesion molecule-1 in human atherosclerosis and their relation to intimal leukocyte content. Circulation. 93:1996;672-682.
48. Konstantopoulos K., McIntyre L.V. Effects of fluid dynamic forces on vascular cell adhesion. J Clin Invest. 98:1996;2661-2665.
49. Frenette P.S., Wagner D.D. Insights into selectin function from knockout mice. Thromb Haemost. 78:1997;60-64.
50. Mayadas T.N., Johnson R.C., Rayburn H., Hynes R.O., Wagner D.D. Leukocyte rolling and extravasation are severely compromised in P-selectin-deficient mice. Cell. 74:1993;541-554.
51. Bullard D.C., Kunkel E.J., Kubo H., et al. Infectious susceptibility and severe deficiency of leukocyte rolling and recruitment in E-selectin and P-selectin double mutant mice. J Exp Med. 183:1996;2329.
52. Dong Z.M., Wagner D.D., Hynes R.O., Frenette P.S., Brown A.A., Chapman S.M. The combined role of P- and E-selectins in atherosclerosis. J Clin Invest. 102:1998;145-152.
53. Albelda S.M., Smith C.W., Ward P.A. Adhesion molecules and inflammatory injury. FASEB J. 8:1994;504-512.
54. Jiang Y., Beller D.I., Frendl G., Graves D.T. Monocyte chemoattractant protein-1 regulates adhesion molecule expression and cytokine production in human monocytes. J Immunol. 148:1992;2423-2423.
55. Brown M.S., Goldstein J.L. A receptor-mediated pathway for cholesterol homeostasis. Science. 232:1986;34-47.
56. Steinberg D. Low density lipoprotein oxidation and its pathobiological significance. J Biol Chem. 272:1997;20963-20966.
57. McEver R.P. Leukocyte-endothelial interactions. Curr Opin Cell Biol. 4:1992;840-849.
58. Johnson-Tidey R.R., McGregor J.L., Taylor P.R., Poston R.N. Increase in the adhesion molecule P-selectin in endothelium overlying atherosclerotic plaques. Coexpression with intercellular adhesion molecule-1. Am J Pathol. 144:1994;952-961.
59. Lehr H.A., Hubner C., Nolte D., Finckh B., Beisiegel U., Kohlschutter A., Messmer K. Oxidatively modified human low-density lipoprotein stimulates leukocyte adherence to the microvascular endothelium in vivo. Res Exp Med (Berlin). 191:1991;85-90.
60. Erl W., Weber P.C., Weber C. Monocytic cell adhesion to endothelial cells stimulated by oxidized low density lipoprotein is mediated by distinct endothelial ligands. Atherosclerosis. 136:1998;297-303.
61. Khan B.V., Parthasarathy S.S., Alexander R.W., Medford R.M. Modified low density lipoprotein and its constituents augment cytokine-activated vascular cell adhesion molecule-1 gene expression in human vascular endothelial cells. J Clin Invest. 95:1995;1262-1270.
62. Kume N., Gimbrone M.A.J. Lysophosphatidylcholine transcriptionally induces growth factor gene expression in cultured human endothelial cells. J Clin Invest. 93:1994;907-911.
63. Kume N., Cybulsky M.I., Gimbrone M.A. Jr. Lysophosphatidylcholine, a component of atherogenic lipoproteins, induces mononuclear leukocyte adhesion molecules in cultured human and rabbit arterial endothelial cells. J Clin Invest. 90:1992;1138-1144.
64. Weber C., Erl W., Pietsch A., Strobel M., Ziegler-Heitbrock H.W., Weber P.C. Antioxidants inhibit monocyte adhesion by suppressing nuclear factor-kappa B mobilization and induction of vascular cell adhesion molecule-1 in endothelial cells stimulated to generate radicals. Arterioscler Thromb. 14:1994;1665-1673.
65. Spiecker M., Darius H., Kaboth K., Hubner F., Liao J.K. Differential regulation of endothelial cell adhesion molecule expression by nitric oxide donors and antioxidants. J Leuk Biol. 63:1998;732-739.
66. Barbeau M.L., Whitman S.C., Rogers K.A. Probucol, but not MaxEPA fish oil, inhibits mononuclear cell adhesion to the aortic intima in the rat model of atherosclerosis. Biochem Cell Biol. 73:1995;283-288.
67. Kaneko M., Hayashi J., Saito I., Miyasaka N. Probucol downregulates E-selectin expression on cultured human vascular endothelial cells. Arterioscler Thromb Vasc Biol. 16:1996;1047-1051.
68. Andersen B., Goldsmith G.H., Spagnuolo P.J. Neutrophil adhesive dysfunction in diabetes mellitus; the role of cellular and plasma factors. J Lab Clin Med. 111:1988;275-285.
69. Brownlee M., Cerami A., Vlassara H. Advanced glycosylation end products in tissue and the biochemical basis of diabetic complications. NEJM. 318:1988;1315-1321.
70. Schmidt A.M., Hori O., Chen J.X., et al. Advanced glycation endproducts interacting with their endothelial receptor induce expression of vascular cell adhesion molecule-1 (VCAM-1) in cultured human endothelial cells and in mice. A potential mechanism for the accelerated vasculopathy of diabetes. J Clin Invest. 96:1995;1395-1403.
71. Vlassara H., Fuh H., Donnelly T., Cybulsky M. Advanced glycation endproducts promote adhesion molecule (VCAM-1, ICAM-1) expression and atheroma formation in normal rabbits. Mol Med. 1:1995;447-456.
72. Rattan V., Shen Y., Sultana C., Kumar D., Kalra V.K. Diabetic RBC-induced oxidant stress leads to transendothelial migration of monocyte-like KL-60 cells. Am J Physiol. 273:1997;E369-E375.
73. Morigi M., Angioletti S., Imberti B., et al. Leukocyte-endothelial interaction is augmented by high glucose concentrations and hyperglycemia in a NF-kB-dependent fashion. J Clin Invest. 101:1998;1905-1915.
74. Kalra V.K., Ying Y., Deemer K., Natarajan R., Nadler J.L., Coates T.D. Mechanism of cigarette smoke condensate induced adhesion of human monocytes to cultured endothelial cells. J Cell Physiol. 160:1994;154-162.
75. Dovgan P.S., Edwards J.D., Zhan X., Wilde M., Agrawal D.K. Cigarette smoking increases monocyte adherence to cultured endothelial cell monolayer. Biochem Biophys Res Commun. 203:1994;929-934.
76. Shen Y., Rattan V., Sultana C., Kalra V.K. Cigarette smoke condensate-induced adhesion molecule expression and transendothelial migration of monocytes. Am J Physiol. 270:1996;H1624-H1633.
77. Powell J.T. Vascular damage from smoking disease mechanisms at the arterial wall . Vasc Med. 3:1998;21-28.
78. Lehr H.A., Frei B., Arfors K.E. Vitamin C prevents cigarette smoke-induced leukocyte aggregation and adhesion to endothelium in vivo. Proc Nat Acad Sci (USA). 91:1994;7688-7692.
79. Weber C., Erl W., Weber K., Weber P.C. Increased adhesiveness of isolated monocytes to endothelium is prevented by vitamin C intake in smokers. Circulation. 93:1996;1488-1492.
80. Lehr H.A., Weyrich A.S., Saetzler R.K., et al. Vitamin C blocks inflammatory platelet-activating factor mimetics created by cigarette smoking. J Clin Invest. 99:1997;2358-2364.
81. Adams M.R., Jessup W., Celermajer D.S. Cigarette smoking is associated with increased human monocyte adhesion to endothelial cells reversibility with oral L-arginine but not vitamin C . J Am Coll Cardiol. 29:1997;491-497.
82. Welch G.N., Loscalzo J. Homocysteine and atherothrombosis. NEJM. 338:1998;1042-1050.
83. Harker L.A., Slichter S.J., Scott C.R., Ross R. Homocystinemia vascular injury and arterial thrombosis . NEJM. 291:1974;537-543.
84. Harker L.A., Ross R., Slichter S.J., Scott C.R. Homocystine-induced atherosclerosis the role of endothelial cell injury and platelet response in its genesis . J Clin Invest. 58:1976;731-741.
85. James T.N. The spectrum of diseases of small coronary arteries and their physiologic consequences. J Am Coll Cardiol. 15:1990;763-774.
86. Heinecke J.W. Superoxide-mediated oxidation of low density lipoprotein by thiols. Cerutti P.A., Fridovich I., McCord J.M., Oxy-radicals in Molecular Biology and Pathology. 1988;443-457 Alan R. Liss, New York.
87. Heinecke J.W., Rosen H., Suzuki L.A., Chait A. The role of sulfur-containing amino acids in superoxide production and modification of low density lipoprotein by arterial smooth muscle cells. J Biol Chem. 262:1987;10098-10103.
88. Ratnoff O.D. Activation of Hageman factor by L-homocystine. Science. 162:1968;1007-1009.
89. Rodgers G.M., Kane W.H. Activation of endogenous factor V by a homocysteine-induced vascular endothelial cell activator. J Clin Invest. 77:1986;1909-1916.
90. Rodgers G.M., Conn M.T. Homocysteine, an atherogenic stimulus, reduces protein C activation by arterial and venous endothelial cells. Blood. 75:1990;895-901.
91. Lentz S.R., Sadler J.E. Inhibition of thrombomodulin surface expression and protein C activation by the thrombogenic agent homocysteine. J Clin Invest. 88:1991;1906-1914.
92. Fryer R.H., Wilson B.D., Gubler D.B., Fitzgerald L.A., Rodgers G.M. Homocysteine, a risk factor for premature vascular disease and thrombosis, induces tissue factor activity in endothelial cells. Arterioscler Thromb. 13:1993;1327-1333.
93. Nishinaga M., Ozawa T., Shimada K. Homocysteine, a thrombogenic agent, suppresses anticoagulant heparan sulfate expression in cultured porcine aortic endothelial cells. J Clin Invest. 92:1993;1381-1386.
94. Welch G.N., Upchurch G.R. Jr, Loscalzo J. Hyperhomocyst(e)inemia and atherothrombosis. Ann N Y Acad Sci. 811:1997;48-58.
95. Loscalzo J. The oxidant stress of hyperhomocyst(e)inemia. J Clin Invest. 98:1996;5-7.
96. Tsai J.C., Wang H., Perrella M.A., et al. Induction of cyclin A gene expression by homocysteine in vascular smooth muscle cells. J Clin Invest. 97:1996;146-153.
97. Welch G.N., Upchurch G.R. Jr, Farivar R.S., et al. Homocysteine-induced nitric oxide production in vascular smooth muscle cells by NF-(kappa)B dependent transcriptional activation of Nos2. Proc Am Assoc Physicians. 110:1998;22-31.
98. Bellas R.E., Lee J.S., Sonenshein G.E. Expression of a constitutive NF-kappa B-like activity is essential for proliferation of cultured bovine vascular smooth muscle cells. J Clin Invest. 96:1995;2521-2527.
99. Asakura T., Karino T. Flow patterns and spatial distribution of atherosclerotic lesions in human coronary arteries. Circ Res. 66:1990;1045-1066.
100. Wapola P.L., Gotlieb A.I., Cybulsky M.I., Langille B.L. Expression of ICAM-1 and VCAM-1 and monocyte adherence in arteries exposed to altered shear stress. Arterioscler Thromb Vasc Biol. 15:1995;2-10.
101. Sprague E.A., Cayatte A.J., Valente A.J., Schwartz C.J. Flow-mediated modulation of selected biologic and molecular determinants related to vascular endothelial activation. J Vasc Surg. 15:1992;919-921.
102. Ohtsuka A., Ando J., Korenaga R., Kamiya A., Toyama-Sorimachi N., Miyasaka M. The effect of flow on the expression of vascular adhesion molecule-1 by cultured mouse endothelial cells. Biochem Biophys Res Commun. 193:1993;303-310.
103. Nagel T., Resnick N., Atkinson W.J., Dewey C.F., Gimbrone M.A. Shear stress selectively upregulates intracellular adhesion molecule-1 expression in cultured human vascular endothelial cells. J Clin Invest. 94:1994;885-891.
104. Martin A., Foxall T., Blumberg J.B., Meydani M. Vitamin E inhibits low-density lipoprotein-induced adhesion of monocytes to human aortic endothelial cells in vitro. Arterioscler Thromb Vasc Biol. 17:1997;429-436.
105. Pohl U., Holtz J., Busse R., Bassenge E. Crucial role of endothelium in the vasodilator response to increased flow in vivo. Hypertension. 8:1986;37-44.
106. Cooke J.P., Stamler J., Andon N., Davies P.F., McKinley, G, Loscalzo J. Flow stimulates endothelial cells to release a nitrovasodilator that is potentiated by reduced thiol. Am J Physiol. 259:1990;H804-H812.
107. Cooke J.P., Rossitch E. Jr, Andon N.A., Loscalzo J., Dzau V.J. Flow activates an endothelial potassium channel to release an endogenous nitrovasodilator. J Clin Invest. 88:1991;1663-1671.
108. Tsao P.S., Buitrago R., Chan J.R., Cooke J.P. Fluid flow inhibits endothelial adhesiveness. Nitric oxide and transcriptional regulation of VCAM-1. Circulation. 94:1996;1682-1689.
109. Nagel T., Resnick N., Atkinson W.J., Dewey C.F., Gimbrone M.A. Shear stress selectively upregulates intracellular adhesion molecule-1 expression in cultured human vascular endothelial cells. J Clin Invest. 94:1994;885-891.
110. Resnick N., Collins T., Atkinson W., Bonthron D.T., Dewey C.F. Jr, Gimbrone M.A. Jr. Platelet-derived growth factor B chain promoter contains a cis-acting fluid shear-stress-responsive element. Proc Natl Acad Sci. (USA). 90:1993;4591-4595.
111. Gimbrone M.A., Nagel T., Topper J.N. Biomechanical activation an emerging paradigm in endothelial adhesion biology . J Clin Invest. 100:1997;61S-65S.
112. Ando J., Tsuboi H., Korenaga R., et al. Down-regulation of vascular adhesion molecule-1 by fluid shear stress in cultured mouse endothelial cells. Ann N Y Acad Sci. 748:1995;148-156.
113. Malek A.M., Greene A.L., Izumo S. Regulation of endothelin 1 gene by fluid shear stress is transcriptionally mediated and independent of protein kinase C and cAMP. Proc Natl Acad Sci. (USA). 90:1993;5999-6003.
114. Korenaga R., Ando J., Kosaki K., Isshiki M., Takada Y., Kamiya A. Negative transcriptional regulation of the VCAM-1 gene by fluid shear stress in murine endothelial cells. Am J Physiol. 273:1997;C1506-C1515.
115. McCarron R.M., Wang L., Siren A.L., Spatz M., Hallenbeck J.M. Adhesion molecules on normotensive and hypertensive rat brain endothelial cells. Proc Soc Exp Biol Med. 205:1994;257-262.
116. Komatsu S., Panes J., Russell J.M., et al. Effects of chronic arterial hypertension on constitutive and induced intercellular adhesion molecule-1 expression in vivo. Hypertension. 29:1997;683-689.
117. McCarron R.M., Wang L., Siren A.L., Spatz M., Hallenbeck J.M. Monocyte adhesion to cerebrovascular endothelial cells derived from hypertensive and normotensive rats. Am J Physiol. 267:1994;H2491-H2497.
118. Blann A.D., Tse W., Maxwell S.J., Waite M.A. Increased levels of the soluble adhesion molecule E-selectin in essential hypertension. J Hypertens. 12:1994;925-928.
119. DeWood M.A., Spores J., Notske R., et al. Prevalence of total coronary occlusion during the early hours of transmural myocardial infarction. NEJM. 303:1980;897-902.
120. Rabbani L.E., Loscalzo J. Recent observations on the role of hemostatic determinants in the development of the atherothrombotic plaque. Atherosclerosis. 105:1994;1-7.
121. Bini A., Fenoglio J.J. Jr, Mesa-Tejada R., Kudryk B., Kaplan K.L. Identification and distribution of fibrinogen, fibrin, and fibrin(ogen) degradation products in atherosclerosis. Use of monoclonal antibodies. Arteriosclerosis. 9:1989;109-121.
122. Smith E.B., Keen G.A., Grant A., Stirk C. Fate of fibrinogen in human arterial intima. Arteriosclerosis. 10:1990;263-275.
123. Meade T.W., Mellows S., Brozovic M., et al. Haemostatic function and ischaemic heart disease principal results of the Northwick Park Heart Study . Lancet. 2:1986;533-537.
124. Kannel W.B., Wolf P.A., Castelli W.P., D'Agostino R.B. Fibrinogen and risk of cardiovascular disease. The Framingham Study. JAMA. 258:1987;1183-1186.
125. Hamsten A., Wiman B., de Faire U., Blomback M. Increased plasma levels of a rapid inhibitor of tissue plasminogen activator in young survivors of myocardial infarction. NEJM. 313:1985;1557-1563.
126. Ridker P.M., Vaughan D.E., Stampfer M.J., Manson J.E., Hennekens C.H. Endogenous tissue-type plasminogen activator and risk of myocardial infarction. Lancet. 341:1993;1165-1168.
127. Stampfer M.J., Malinow M.R., Willett W.C., et al. A prospective study of plasma homocyst(e)ine and risk of myocardial infarction in US physicians. JAMA. 268:1992;877-881.
128. Malinow M.R., Nieto F.J., Szklo M., Chambless L.E., Bond G. Carotid artery intimal-medial wall thickening and plasma homocyst(e)ine in asymptomatic adults. The Atherosclerosis Risk in Communities Study. Circulation. 87:1993;1107-1113.
129. Kruth H.S. Platelet-mediated cholesterol accumulation in cultured aortic smooth muscle cells. Science. 227:1985;1243-1245.
130. Mendelsohn M.E., Loscalzo J. Role of platelets in cholesteryl ester formation by U-937 cells. J Clin Invest. 81:1988;62-68.
131. Jang Y., Lincoff A.M., Plow E.F., Topol E.J. Cell adhesion molecules in coronary artery disease. J Am Coll Cardiol. 24:1994;1591-1601.
132. Friedman R.J., Stemerman M.B., Wenz B., et al. The effect of thrombocytopenia on experimental arteriosclerotic lesion formation in rabbits. Smooth muscle cell proliferation and re-endothelialization. J Clin Invest. 60:1977;1191-1201.
133. Jones A., Geczy C.L. Thrombin and factor Xa enhance the production of interleukin-1. Immunology. 71:1990;236-241.
134. Dustin M.L., Rothlein R., Bhan A.K., Dinarello C.A., Springer T.A. Induction by IL 1 and interferon-gamma tissue distribution, biochemistry, and function of a natural adherence molecule (ICAM-1) . J Immunol. 137:1986;245-254.
135. Libby P., Warner S.J., Friedman G.B. Interleukin 1 a mitogen for human vascular smooth muscle cells that induces the release of growth-inhibitory prostanoids . J Clin Invest. 81:1988;487-498.
136. Gold H.K., Gimple L.W., Yasuda T., et al. Pharmacodynamic study of F(ab′)2 fragments of murine monoclonal antibody 7E3 directed against human platelet glycoprotein IIb/IIIa in patients with unstable angina pectoris. J Clin Invest. 86:1990;651-659.
137. Use of a monoclonal antibody directed against the platelet glycoprotein IIb/IIIa receptor in high-risk coronary angioplasty. The EPIC Investigation. N Engl J Med 1994;330:956-961.
138. Coller B.S. A new murine monoclonal antibody reports an activation-dependent change in the conformation and/or microenvironment of the platelet glycoprotein IIb/IIIa complex. J Clin Invest. 76:1985;101-108.
139. Le Breton H., Plow E.F., Topol E.J. Role of platelets in restenosis after percutaneous coronary revascularization. J Am Coll Cardiol. 28:1996;1643-1651.
140. Lee R.T., Berditchevski F., Cheng G.C., Hemler M.E. Integrin-mediated collagen matrix reorganization by cultured human vascular smooth muscle cells. Circ Res. 76:1995;209-214.
141. Lin T.H., Yurochko A., Kornberg L., et al. The role of protein tyrosine phosphorylation in integrin-mediated gene induction in monocytes. J Cell Biol. 126:1994;1585-1593.
142. Haskill S., Johnson C., Eierman D., Becker S., Warren K. Adherence induces selective mRNA expression of monocyte mediators and proto-oncogenes. J Immunol. 140:1988;1690-1694.
143. Fan S.T., Mackman N., Cui M.Z., Edgington T.S. Integrin regulation of an inflammatory effector gene. Direct induction of the tissue factor promoter by engagement of beta 1 or alpha 4 integrin chains. J Immunol. 154:1995;3266-3274.
144. Moroi M., Jung S.M. Platelet receptors for collagen. Thromb Haemost. 78:1997;439-444.
145. Haimovich B., Lipfert L., Brugge J.S., Shattil S.J. Tyrosine phosphorylation and cytoskeletal reorganization in platelets are triggered by interaction of integrin receptors with their immobilized ligands. J Biol Chem. 268:1993;15868-15877.
146. Gawaz M., Neumann F.J., Dickfeld T., et al. Vitronectin receptor (alpha(v)beta3) mediates platelet adhesion to the luminal aspect of endothelial cells implications for reperfusion in acute myocardial infarction . Circulation. 96:1997;1809-1818.
147. Dufourcq P., Louis H., Moreau C., et al. Vitronectin expression and interaction with receptors in smooth muscle cells from human atheromatous plaque. Arterioscler Thromb Vasc Biol. 18:1998;168-176.
148. van Aken B.E., Seiffert D., Thinnes T., Loskutoff D.J. Localization of vitronectin in the normal and atherosclerotic human vessel wall. Histochem Cell Biol. 107:1997;313-320.
149. Bobbink I.W., de Boer H.C., Tekelenburg W.L., Banga J.D., de Groot P.G. Effect of extracellular matrix glycation on endothelial cell adhesion and spreading involvement of vitronectin . Diabetes. 46:1997;87-93.
150. Bevilacqua M.P., Nelson R.M., Mannori G., Cecconi O. Endothelial-leukocyte adhesion molecules in human disease. Annu Rev Med. 45:1994;361-378.
151. Peter K., Nawroth P., Conradt C., et al. Circulating vascular cell adhesion molecule-1 correlates with the extent of human atherosclerosis in contrast to circulating intercellular adhesion molecule-1, E-selectin, P-selectin, and thrombomodulin. Arterioscler Thromb Vasc Biol. 17:1997;505-512.
152. Blann A.D., McCollum C.N. Circulating endothelial cell/leukocyte adhesion molecules in atherosclerosis. Thromb Haemost. 72:1994;151-154.
153. Hackman A., Abe Y., Insull W. Jr, et al. Levels of soluble cell adhesion molecules in patients with dyslipidemia. Circulation. 93:1996;1334-1338.
154. Ridker P.M., Hennekens C.H., Roitman-Johnson B., Stampfer M.J., Allen J. Plasma concentration of soluble intercellular adhesion molecule-1 and risks of future myocardial infarction in apparently healthy men. Lancet. 351:1998;88-92.
155. Blann A.D., Steele C., McCollum C.N. The influence of smoking on soluble adhesion molecules and endothelial cell markers. Thromb Res. 85:1997;433-438.
156. Ridker P.M., Cushman M., Stampfer M.J., Tracy R.P., Hennekens C.H. Inflammation, aspirin, and the risk of cardiovascular disease in apparently healthy men. NEJM. 336:1997;973-979.