Negative transcriptional regulation of the VCAM-1 gene by fluid shear stress in murine endothelial cells

American Journal of Physiology - Cell Physiology

Volumn 273, Issue 5 42-5, 1997, Pages

  Korenaga, Eisa ^a   Ando, Joji ^a   Kosaki, Keisuke ^a   Isshiki, Masashi ^a   Takada, Yoshio ^b   Kamiya, Akira ^a  

^a UNIVERSITY OF TOKYO   (Japan)

^b ASAHI CHEMICAL INDUSTRY CO   (Japan)

Author keywords

c jun; Nuclear factor activator protein 1; Vascular cell adhesion molecule 1; Vascular endothelial cells

Indexed keywords

VASCULAR CELL ADHESION MOLECULE 1;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; ENDOTHELIUM CELL; GENE DELETION; GENE EXPRESSION REGULATION; GENE MUTATION; GENETIC TRANSFECTION; MOUSE; NONHUMAN; PRIORITY JOURNAL; RNA ANALYSIS; SHEAR STRESS; TRANSCRIPTION INITIATION; TRANSCRIPTION REGULATION;

ANIMALIA; MURINAE;

EID: 20644431594     PISSN: 03636143     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpcell.1997.273.5.c1506     Document Type: Article

References (16)

1. Ando, J., and A. Kamiya. Blood flow and vascular endothelial cell function. Front. Med. Biol. Eng. 5: 245-264, 1993.
2. Ando, J., H. Tsuboi, R. Korenaga, Y. Takada, N. Toyama-Sorimachi, M. Miyasaka, and A. Kamiya. Shear stress inhibits adhesion of cultured mouse endothelial cells to lymphocytes by downregulating VCAM-1 expression. Am. J. Physiol. 267 (Cell Physiol. 36): C679-C687, 1994.
3. Cooper, G. M. (Editor). Oncogenes. In: The Jones and Bartlett Series in Biology. Boston, MA: Jones & Bartlett, 1990.
4. Cybulsky, M. I., M. Allan-Motamed, and T. Collins. Structure of the murine VCAM 1 gene. Genomics 18: 387-391, 1993.
5. Diamond, S. L., J. B. Sharefkin, C. Dieffenbach, K. Frasier-Scott, L. V. McIntire, and S. G. Eskin. Tissue plasminogen activator messenger RNA levels increase in cultured human endothelial cells exposed to laminar shear stress. J. Cell. Physiol. 143: 364-371, 1990.
6. Hsieh, H. J., N. Q. Li, and J. A. Frangos. Shear stress increases endothelial platelet-derived growth factor mRNA levels. Am. J. Physiol. 260 (Heart Circ. Physiol. 29): H642-H646, 1991.
7. Hsieh, H. J., N. Q. Li, and J. A. Frangos. Pulsatile and steady flow induces c-fos expression in human endothelial cells. J. Cell. Physiol. 154: 143-151, 1993.
8. Inoue, N., S. Ramasamy, T. Fukai, R. M. Nerem, and D. G. Harrison. Shear stress modulates expression of Cu/Zn superoxide dismutase in human aortic endothelial cells. Circ. Res. 79: 32-37, 1996.
9. Khachigian, L. M., N. Resnick, M. A. Gimbrone, Jr., and T. Collins. Nuclear factor-κB interacts functionally with the platelet-derived growth factor B-chain shear-stress response element in vascular endothelial cells exposed to fluid shear stress. J. Clin. Invest. 96: 1169-1175, 1995.
10. Lan, Q., K. O. Mercurius, and P. F. Davies. Stimulation of transcription factors NFκB and AP-1 in endothelial cells subjected to shear stress. Biochem. Biophys. Res. Commun. 201: 950-956, 1994.
11. Malek, A. M., G. H. Gibbons, V. J. Dzau, and S. Izumo. Fluid shear stress differentially modulates expression of genes encoding basic fibroblast growth factor and platelet-derived growth factor B chain in vascular endothelium. J. Clin. Invest. 92: 2013-2021, 1993.
12. Malek, A. M., A. L. Greene, and S. Izumo. Regulation of endothelin 1 gene by fluid shear stress is transcriptionally mediated and independent of protein kinase C and cAMP. Proc. Natl. Acad. Sci. USA 90: 5999-6003, 1993.
13. Malek, A. M., R. Jackman, R. D. Rosenberg, and S. Izumo. Endothelial expression of thrombomodulin is reversibly regulated by fluid shear stress. Circ. Res. 74: 852-860, 1994.
14. Mitsumata, M., R. S. Fishel, R. M. Nerem, R. W. Alexander, and B. C. Berk. Fluid shear stress stimulates platelet-derived growth factor expression in endothelial cells. Am. J. Physiol. 265 (Heart Circ. Physiol. 34): H3-H8, 1993.
15. Nagel, T., N. Resnick, W. J. Atkinson, C. F. Dewey, Jr., and M. A. Gimbrone, Jr. Shear stress selectively upregulates intercellular adhesion molecule-1 expression in cultured human vascular endothelial cells. J. Clin. Invest. 94: 885-891, 1994.
16. Nishida, K., D. G. Harrison, J. P. Navas, A. A. Fisher, S. P. Dockery, M. Uematsu, R. M. Nerem, R. W. Alexander, and T. J. Murphy. Molecular cloning and characterization of the constitutive bovine aortic endothelial cell nitric oxide synthase. J. Clin. Invest. 90: 2092-2096, 1992.