The bis(naphthalimide) DMP-840 causes cytotoxicity by its action against eukaryotic topoisomerase II

Biochemistry

Volumn 37, Issue 9, 1998, Pages 3078-3085

  Nitiss, John L ^a,b   Zhou, Junfang ^a   Rose, Angela ^a   Hsiung, Yuchu ^b,f   Gale, Kevin C ^c,e   Osheroff, Neil ^d  

^a ST JUDE CHILDREN S RESEARCH HOSPITAL   (United States)

^b UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^c DUPONT COMPANY   (United States)

^d VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^e Amersham Biosciences   (United States)

^f SCRIPPS RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMSACRINE; BISNAFIDE MESYLATE; DNA TOPOISOMERASE; DNA TOPOISOMERASE (ATP HYDROLYSING); ETOPOSIDE;

ANIMAL CELL; ANTINEOPLASTIC ACTIVITY; ARTICLE; CYTOTOXICITY; DRUG TARGETING; ENZYME DEGRADATION; ENZYME PURIFICATION; NONHUMAN; PRIORITY JOURNAL; TEMPERATURE SENSITIVE MUTANT; YEAST CELL;

ALLELES; ANTINEOPLASTIC AGENTS; DNA TOPOISOMERASES, TYPE II; DRUG RESISTANCE, MICROBIAL; HUMANS; IMIDES; ISOQUINOLINES; MESYLATES; NAPHTHALIMIDES; SACCHAROMYCES CEREVISIAE;

EID: 0032478137     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi9723257     Document Type: Article

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