-
1
-
-
0000356472
-
Doxorubicin
-
New York: Academic Press
-
Arcamone, F. Doxorubicin. In: Anticancer Antibiotics. New York: Academic Press, 1981.
-
(1981)
Anticancer Antibiotics
-
-
Arcamone, F.1
-
2
-
-
0030807646
-
A doxorubicin disaccharide analog: Apoptosis-related improvement of efficacy in vivo
-
Arcamone, F., Animati, F., Berettoni, M., Bigioni, M., Capranico, G., Casazza, A. M., Caserini, C., Cipollone, A., De Cesare, M., Franciotti, M., Lombardi, P., Madami, A., Manzini, S., Monteagudo, E., Polizzi, D., Pratesi, G., Righetti, S. C., Salvatore, C., Supino, R., and Zunino, F. A doxorubicin disaccharide analog: apoptosis-related improvement of efficacy in vivo. J. Natl. Cancer Inst., 89: 1217-1223, 1997.
-
(1997)
J. Natl. Cancer Inst.
, vol.89
, pp. 1217-1223
-
-
Arcamone, F.1
Animati, F.2
Berettoni, M.3
Bigioni, M.4
Capranico, G.5
Casazza, A.M.6
Caserini, C.7
Cipollone, A.8
De Cesare, M.9
Franciotti, M.10
Lombardi, P.11
Madami, A.12
Manzini, S.13
Monteagudo, E.14
Polizzi, D.15
Pratesi, G.16
Righetti, S.C.17
Salvatore, C.18
Supino, R.19
Zunino, F.20
more..
-
3
-
-
0031277586
-
New developments in antitumor anthracyclines
-
Arcamone, F., Animati, F., Capranico, G., Lombardi, P., Pratesi, G., Supino, R., and Zunino, F. New developments in antitumor anthracyclines. Pharmacol. Ther., 76: 117-124, 1997.
-
(1997)
Pharmacol. Ther.
, vol.76
, pp. 117-124
-
-
Arcamone, F.1
Animati, F.2
Capranico, G.3
Lombardi, P.4
Pratesi, G.5
Supino, R.6
Zunino, F.7
-
4
-
-
0030826233
-
A protein-mediated mechanism for the DNA sequence-specific action of topoisomerase II poisons
-
Capranico, G., Binaschi, M., Borgnetto, M. E., Zunino, F., and Palumbo, M. A protein-mediated mechanism for the DNA sequence-specific action of topoisomerase II poisons. Trends Pharmacol. Sci., 18: 303-346, 1997.
-
(1997)
Trends Pharmacol. Sci.
, vol.18
, pp. 303-346
-
-
Capranico, G.1
Binaschi, M.2
Borgnetto, M.E.3
Zunino, F.4
Palumbo, M.5
-
5
-
-
0025603165
-
DNA topoisomerase II as the primary target of anti-tumor anthracyclines
-
Zunino, F., and Capranico, G. DNA topoisomerase II as the primary target of anti-tumor anthracyclines. Anti-Cancer Drug Des., 5: 307-317, 1990.
-
(1990)
Anti-Cancer Drug Des.
, vol.5
, pp. 307-317
-
-
Zunino, F.1
Capranico, G.2
-
6
-
-
0000420523
-
DNA topoisomerase II inhibitors
-
B. A. Teicher (ed.), Totowa, NJ: Humana Press
-
Pommier, Y. DNA topoisomerase II inhibitors. In: B. A. Teicher (ed.), Cancer Therapeutics: Experimental and Clinical Agents, pp. 153-174. Totowa, NJ: Humana Press, 1997.
-
(1997)
Cancer Therapeutics: Experimental and Clinical Agents
, pp. 153-174
-
-
Pommier, Y.1
-
7
-
-
0024316466
-
DNA topoisomerase poisons as antitumor drugs
-
Liu, L. F. DNA topoisomerase poisons as antitumor drugs. Annu. Rev. Biochem., 58: 351-375, 1989.
-
(1989)
Annu. Rev. Biochem.
, vol.58
, pp. 351-375
-
-
Liu, L.F.1
-
8
-
-
0025037693
-
Sequence-selective topoisomerase II inhibition by anthracycline derivatives in SV40 DNA: Relationship with DNA binding affinity and cytotoxicity
-
Capranico, G., Zunino, F., Kohn, K. W., and Pommier, Y. Sequence-selective topoisomerase II inhibition by anthracycline derivatives in SV40 DNA: relationship with DNA binding affinity and cytotoxicity. Biochemistry, 29: 562-569, 1990.
-
(1990)
Biochemistry
, vol.29
, pp. 562-569
-
-
Capranico, G.1
Zunino, F.2
Kohn, K.W.3
Pommier, Y.4
-
9
-
-
0029060959
-
Eukaryotic DNA topoisomerase I
-
Gupta, M., Fujimori, A., and Pommier, Y. Eukaryotic DNA topoisomerase I. Biochim. Biophys. Acta, 1262: 1-14, 1995.
-
(1995)
Biochim. Biophys. Acta
, vol.1262
, pp. 1-14
-
-
Gupta, M.1
Fujimori, A.2
Pommier, Y.3
-
10
-
-
0029144134
-
Topoisomerase poisons: Harnessing the dark side of enzyme mechanism
-
Froelich Ammon, S. J., and Osheroff, N. Topoisomerase poisons: harnessing the dark side of enzyme mechanism. J. Biol. Chem., 270: 21429-21432, 1995.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 21429-21432
-
-
Froelich Ammon, S.J.1
Osheroff, N.2
-
11
-
-
0030014783
-
DNA topoisomerases
-
Wang, J. C. DNA topoisomerases. Annu. Rev. Biochem., 65: 635-692, 1996.
-
(1996)
Annu. Rev. Biochem.
, vol.65
, pp. 635-692
-
-
Wang, J.C.1
-
12
-
-
0024388737
-
Differential requirement of DNA replication for the cytotoxicity of DNA topoisomerase I and II inhibitors in Chinese hamster DC3F cells
-
Holm, C., Covey, J. M., Kerrigan, D., and Pommier, Y. Differential requirement of DNA replication for the cytotoxicity of DNA topoisomerase I and II inhibitors in Chinese hamster DC3F cells. Cancer Res., 49: 6365-6368, 1989.
-
(1989)
Cancer Res.
, vol.49
, pp. 6365-6368
-
-
Holm, C.1
Covey, J.M.2
Kerrigan, D.3
Pommier, Y.4
-
13
-
-
0024420685
-
Arrest of replication forks by drug-stabilized topoisomerase I-DNa cleavable complexes as a mechanism of cell killing by camptothecin
-
Hsiang, Y. H., Lihou, M. G., and Liu, L. F. Arrest of replication forks by drug-stabilized topoisomerase I-DNA cleavable complexes as a mechanism of cell killing by camptothecin. Cancer Res., 49: 5077-5082, 1989.
-
(1989)
Cancer Res.
, vol.49
, pp. 5077-5082
-
-
Hsiang, Y.H.1
Lihou, M.G.2
Liu, L.F.3
-
14
-
-
0027945431
-
Disruption of a topoisomerase-DNa cleavage complex by a DNA helicase
-
Howard, M. T., Neece, S. H., Matson, S. W., and Kreuzer, K. N. Disruption of a topoisomerase-DNA cleavage complex by a DNA helicase. Proc. Natl. Acad. Sci. USA, 91: 12031-12035, 1994.
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.91
, pp. 12031-12035
-
-
Howard, M.T.1
Neece, S.H.2
Matson, S.W.3
Kreuzer, K.N.4
-
15
-
-
0011173714
-
DNA topoisomerase II mutant of Saccharomyces cerevisiae: Topoisomerase II is required for segregation of daughter molecules at the termination of DNA replication
-
DiNardo, S., Voelkel, K., and Sternglanz, R. DNA topoisomerase II mutant of Saccharomyces cerevisiae: topoisomerase II is required for segregation of daughter molecules at the termination of DNA replication. Proc. Natl. Acad. Sci. USA, 81: 2616-2620, 1984.
-
(1984)
Proc. Natl. Acad. Sci. USA
, vol.81
, pp. 2616-2620
-
-
DiNardo, S.1
Voelkel, K.2
Sternglanz, R.3
-
16
-
-
0021185946
-
Yeast DNA topoisomerase II is encoded by a single-copy, essential gene
-
Goto, T., and Wang, J. C. Yeast DNA topoisomerase II is encoded by a single-copy, essential gene. Cell, 36: 1073-1080, 1984.
-
(1984)
Cell
, vol.36
, pp. 1073-1080
-
-
Goto, T.1
Wang, J.C.2
-
17
-
-
0023651332
-
DNA topoisomerase II is required for condensation and separation of mitotic chromosomes in S. pombe
-
Uemura, T., Ohkura, H., Adachi, Y., Morino, K., Shiozaki, K., and Yanagida, M. DNA topoisomerase II is required for condensation and separation of mitotic chromosomes in S. pombe. Cell, 50: 917-925, 1987.
-
(1987)
Cell
, vol.50
, pp. 917-925
-
-
Uemura, T.1
Ohkura, H.2
Adachi, Y.3
Morino, K.4
Shiozaki, K.5
Yanagida, M.6
-
18
-
-
0027402476
-
A temperature sensitive topoisomerase II allele confers temperature dependent drug resistance on amsacrine and etoposide: A genetic system for determining the targets of topoisomerase II inhibitors
-
Nitiss, J. L., Liu, Y. X., and Hsiung, Y. A temperature sensitive topoisomerase II allele confers temperature dependent drug resistance on amsacrine and etoposide: a genetic system for determining the targets of topoisomerase II inhibitors. Cancer Res., 53: 89-93, 1993.
-
(1993)
Cancer Res.
, vol.53
, pp. 89-93
-
-
Nitiss, J.L.1
Liu, Y.X.2
Hsiung, Y.3
-
19
-
-
0027163315
-
The top2-5 mutant of yeast topoisomerase II encodes an enzyme resistant to etoposide and amsacrine
-
Jannatipour, M., Liu, Y-X., and Nitiss, J. L. The top2-5 mutant of yeast topoisomerase II encodes an enzyme resistant to etoposide and amsacrine. J. Biol. Chem., 268: 18586-18592, 1993.
-
(1993)
J. Biol. Chem.
, vol.268
, pp. 18586-18592
-
-
Jannatipour, M.1
Liu, Y.-X.2
Nitiss, J.L.3
-
20
-
-
0026794617
-
Amsacrine and etoposide hypersensitivity of yeast cells overexpressing DNA topoisomerase II
-
Nitiss, J. L., Liu, Y. X., Harbury, P., Jannatipour, M., Wasserman, R., and Wang, J. C. Amsacrine and etoposide hypersensitivity of yeast cells overexpressing DNA topoisomerase II. Cancer Res., 52: 4467-4472, 1992.
-
(1992)
Cancer Res.
, vol.52
, pp. 4467-4472
-
-
Nitiss, J.L.1
Liu, Y.X.2
Harbury, P.3
Jannatipour, M.4
Wasserman, R.5
Wang, J.C.6
-
21
-
-
0024229066
-
Evidence that DNA topoisomerase I is necessary for the cytotoxic effects of camptothecin
-
Eng, W. K., Faucette, L., Johnson, R. K., and Sternglanz, R. Evidence that DNA topoisomerase I is necessary for the cytotoxic effects of camptothecin. Mol. Pharmacol., 34: 755-760, 1988.
-
(1988)
Mol. Pharmacol.
, vol.34
, pp. 755-760
-
-
Eng, W.K.1
Faucette, L.2
Johnson, R.K.3
Sternglanz, R.4
-
22
-
-
0026628327
-
Cytotoxicity of quinulones toward eukaryotic cells: Identification of topoisomerase II as the primary cellular target for the quinolone CP-115,953 in yeast
-
Elsea, S. H., Osheroff, N., and Nitiss, J. L. Cytotoxicity of quinulones toward eukaryotic cells: identification of topoisomerase II as the primary cellular target for the quinolone CP-115,953 in yeast. J. Biol. Chem., 267: 13150-13153, 1992.
-
(1992)
J. Biol. Chem.
, vol.267
, pp. 13150-13153
-
-
Elsea, S.H.1
Osheroff, N.2
Nitiss, J.L.3
-
23
-
-
0030973427
-
Camptothecin sensitivity is mediated by the pleiotropic drug resistance network in yeast
-
Reid, R. J., Kauh, E. A., and Bjornsti, M. A. Camptothecin sensitivity is mediated by the pleiotropic drug resistance network in yeast. J. Biol. Chem., 272: 12091-12099, 1997.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 12091-12099
-
-
Reid, R.J.1
Kauh, E.A.2
Bjornsti, M.A.3
-
24
-
-
0027248881
-
Ixr1, a yeast protein that binds to platinated DNa and confers sensitivity to cisplatin
-
Washington DC
-
Brown, S. J., Kellett, P. J., and Lippard, S. J. Ixr1, a yeast protein that binds to platinated DNA and confers sensitivity to cisplatin. Science (Washington DC), 261: 603-605, 1993.
-
(1993)
Science
, vol.261
, pp. 603-605
-
-
Brown, S.J.1
Kellett, P.J.2
Lippard, S.J.3
-
25
-
-
0029740449
-
A Saccharomyces cerevisiae mutant defines a new locus essential for resistance to the antitumour drug bleomycin
-
Ramotar, D., and Masson, J. Y. A Saccharomyces cerevisiae mutant defines a new locus essential for resistance to the antitumour drug bleomycin. Can. J. Microbiol., 42: 835-843, 1996.
-
(1996)
Can. J. Microbiol.
, vol.42
, pp. 835-843
-
-
Ramotar, D.1
Masson, J.Y.2
-
26
-
-
0029758489
-
Active heterodimers are formed from human DNA topoisomerase II α and II β isoforms
-
Biersack, H., Jensen, S., Gromova, I., Nielsen, I. S., Westergaard, O., and Andersen, A. H. Active heterodimers are formed from human DNA topoisomerase II α and II β isoforms. Proc. Natl. Acad. Sci. USA, 93: 8288-8293, 1996.
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 8288-8293
-
-
Biersack, H.1
Jensen, S.2
Gromova, I.3
Nielsen, I.S.4
Westergaard, O.5
Andersen, A.H.6
-
27
-
-
0030747269
-
Cellular distribution of mammalian DNA topoisomerase II is determined by its catalytically dispensable C-terminal domain
-
Adachi, N., Miyaike, M., Kato, S., Kanamaru, R., Koyama, H., and Kikuchi, A. Cellular distribution of mammalian DNA topoisomerase II is determined by its catalytically dispensable C-terminal domain. Nucleic Acids Res., 25: 3135-3142, 1997.
-
(1997)
Nucleic Acids Res.
, vol.25
, pp. 3135-3142
-
-
Adachi, N.1
Miyaike, M.2
Kato, S.3
Kanamaru, R.4
Koyama, H.5
Kikuchi, A.6
-
28
-
-
0027445231
-
Development of improved cell-based assays and screens in Saccharomyces through the combination of molecular and classical genetics
-
Kirsch, D. R. Development of improved cell-based assays and screens in Saccharomyces through the combination of molecular and classical genetics. Curr. Opin. Biotechnol., 4: 543-552, 1993.
-
(1993)
Curr. Opin. Biotechnol.
, vol.4
, pp. 543-552
-
-
Kirsch, D.R.1
-
29
-
-
0000536643
-
DNA topoisomerase-targeting antitumor drugs can be studied in yeast
-
Nitiss, J., and Wang, J. C. DNA topoisomerase-targeting antitumor drugs can be studied in yeast. Proc. Natl. Acad. Sci. USA, 85: 7501-7505, 1988.
-
(1988)
Proc. Natl. Acad. Sci. USA
, vol.85
, pp. 7501-7505
-
-
Nitiss, J.1
Wang, J.C.2
-
30
-
-
0027275284
-
Use of yeast in the study of anticancer drugs targeling DNa topoisomerases: Expression of a functional recombinant human DNa topoisomerase IIα in yeast
-
Wasserman, R. A., Austin, C. A., Fisher, L. M., and Wang, J. C. Use of yeast in the study of anticancer drugs targeling DNA topoisomerases: expression of a functional recombinant human DNA topoisomerase IIα in yeast. Cancer Res., 53: 3591-3596, 1993.
-
(1993)
Cancer Res.
, vol.53
, pp. 3591-3596
-
-
Wasserman, R.A.1
Austin, C.A.2
Fisher, L.M.3
Wang, J.C.4
-
31
-
-
0024519424
-
Inducible overexpression, purification, and active site mapping of DNA topoisomerase II from the yeast Saccharomyces cerevisiae
-
Worland, S. T., and Wang, J. C. Inducible overexpression, purification, and active site mapping of DNA topoisomerase II from the yeast Saccharomyces cerevisiae. J. Biol. Chem., 264: 4412-4416, 1989.
-
(1989)
J. Biol. Chem.
, vol.264
, pp. 4412-4416
-
-
Worland, S.T.1
Wang, J.C.2
-
32
-
-
0025027323
-
Local sequence requirements for DNA cleavage by mammalian topoisomerase II in the presence of doxorubicin
-
Capranico, G., Kohn, K. W., and Pommier, Y. Local sequence requirements for DNA cleavage by mammalian topoisomerase II in the presence of doxorubicin. Nucleic Acids Res., 18: 6611-6619, 1990.
-
(1990)
Nucleic Acids Res.
, vol.18
, pp. 6611-6619
-
-
Capranico, G.1
Kohn, K.W.2
Pommier, Y.3
-
33
-
-
0022979405
-
Single-strand DNA breaks induced by chromophore-modified anthracyclines in P388 leukemia cells
-
Capranico, G., Soranzo, C., and Zunino, F. Single-strand DNA breaks induced by chromophore-modified anthracyclines in P388 leukemia cells. Cancer Res., 46: 5499-5503, 1986.
-
(1986)
Cancer Res.
, vol.46
, pp. 5499-5503
-
-
Capranico, G.1
Soranzo, C.2
Zunino, F.3
-
34
-
-
0029905883
-
Human DNA topoisomerases IIα and IIβ can functionally substitute for yeast TOP2 in chromosome segregation and recombination
-
Jensen, S., Redwood, C. S., Jenkins, J. R., Andersen, A. H., and Hickson, I. D. Human DNA topoisomerases IIα and IIβ can functionally substitute for yeast TOP2 in chromosome segregation and recombination. Mol. Gen. Genet., 252: 79-86, 1996.
-
(1996)
Mol. Gen. Genet.
, vol.252
, pp. 79-86
-
-
Jensen, S.1
Redwood, C.S.2
Jenkins, J.R.3
Andersen, A.H.4
Hickson, I.D.5
-
35
-
-
0031014248
-
Complementation of temperature-sensitive topoisomerase II mutations in Saccharomyces cerevisiae by a human TOP2 β construct allows the study of topoisomerase IIβ inhibitors in yeast
-
Meczes, E. L., Marsh, K. L., Fisher, L. M., Rogers, M. P., and Austin, C. A. Complementation of temperature-sensitive topoisomerase II mutations in Saccharomyces cerevisiae by a human TOP2 β construct allows the study of topoisomerase IIβ inhibitors in yeast. Cancer Chemother. Pharmacol., 39: 367-375, 1997.
-
(1997)
Cancer Chemother. Pharmacol.
, vol.39
, pp. 367-375
-
-
Meczes, E.L.1
Marsh, K.L.2
Fisher, L.M.3
Rogers, M.P.4
Austin, C.A.5
-
36
-
-
0030962254
-
Relationship between lethal effects and topoisomerase II-mediated double-stranded DNA breaks produced by anthracyclines with different sequence specificity
-
Binaschi, M., Capranico, G., Dal Bo, L., and Zunino, F. Relationship between lethal effects and topoisomerase II-mediated double-stranded DNA breaks produced by anthracyclines with different sequence specificity. Mol. Pharmacol., 51: 1053-1059, 1997.
-
(1997)
Mol. Pharmacol.
, vol.51
, pp. 1053-1059
-
-
Binaschi, M.1
Capranico, G.2
Dal Bo, L.3
Zunino, F.4
-
37
-
-
0028304459
-
Influence of structural modifications at the 3′ and 4′ positions of doxorubicin on the drug ability to trap topoisomerase II and to overcome multidrug resistance
-
Capranico, G., Supino, R., Binaschi, M., Capolongo, L., Grandi, M., Suarato, A., and Zunino, F. Influence of structural modifications at the 3′ and 4′ positions of doxorubicin on the drug ability to trap topoisomerase II and to overcome multidrug resistance. Mol. Pharmacol., 45: 908-915, 1994.
-
(1994)
Mol. Pharmacol.
, vol.45
, pp. 908-915
-
-
Capranico, G.1
Supino, R.2
Binaschi, M.3
Capolongo, L.4
Grandi, M.5
Suarato, A.6
Zunino, F.7
-
38
-
-
0028814479
-
Change of the sequence specificity of daunorubicin-stimulated topoisomerase II DNA cleavage by epimerization of the amino group of the sugar moiety
-
Capranico, G., Butelli, E., and Zunino, F. Change of the sequence specificity of daunorubicin-stimulated topoisomerase II DNA cleavage by epimerization of the amino group of the sugar moiety. Cancer Res., 55: 312-317, 1995.
-
(1995)
Cancer Res.
, vol.55
, pp. 312-317
-
-
Capranico, G.1
Butelli, E.2
Zunino, F.3
-
39
-
-
0026642518
-
Differential effects of amsacrine and epipodophyllotoxins on topoisomerase II cleavage in the human c-myc protooncogene
-
Pommier, Y., Orr, A., Kohn, K. W., and Riou, J. F. Differential effects of amsacrine and epipodophyllotoxins on topoisomerase II cleavage in the human c-myc protooncogene. Cancer Res., 52: 3125-3130, 1992.
-
(1992)
Cancer Res.
, vol.52
, pp. 3125-3130
-
-
Pommier, Y.1
Orr, A.2
Kohn, K.W.3
Riou, J.F.4
-
40
-
-
0029922061
-
Drug-specific sites of topoisomerase II DNA cleavage in Drosophila chromatin: Heterogeneous localization and reversibility
-
Borgnetto, M. E., Zunino, F., Tinelli, S., Kas, E., and Capranico, G. Drug-specific sites of topoisomerase II DNA cleavage in Drosophila chromatin: heterogeneous localization and reversibility. Cancer Res., 56: 1855-1862, 1996.
-
(1996)
Cancer Res.
, vol.56
, pp. 1855-1862
-
-
Borgnetto, M.E.1
Zunino, F.2
Tinelli, S.3
Kas, E.4
Capranico, G.5
-
41
-
-
0024305936
-
Expression of human DNA topoisomerase I in yeast cells lacking yeast DNA topoisomerase I: Restoration of sensitivity of the cells to the antitumor drug camptothecin
-
Bjornsti, M. A., Benedetti, P., Viglianti, G. A., and Wang, J. C. Expression of human DNA topoisomerase I in yeast cells lacking yeast DNA topoisomerase I: restoration of sensitivity of the cells to the antitumor drug camptothecin. Cancer Res., 49: 6318-6323, 1989.
-
(1989)
Cancer Res.
, vol.49
, pp. 6318-6323
-
-
Bjornsti, M.A.1
Benedetti, P.2
Viglianti, G.A.3
Wang, J.C.4
-
42
-
-
0029046736
-
DNA topoisomerase II is the molecular target of bisdioxopiperazine derivatives ICRF-159 and ICRF-193 in Saccharomyces cerevisiae
-
Ishida, R., Hamatake, M., Wasserman, R. A., Nitiss, J., Wang, J. C., and Andoh, T. DNA topoisomerase II is the molecular target of bisdioxopiperazine derivatives ICRF-159 and ICRF-193 in Saccharomyces cerevisiae. Cancer Res., 55: 2299-2303, 1995.
-
(1995)
Cancer Res.
, vol.55
, pp. 2299-2303
-
-
Ishida, R.1
Hamatake, M.2
Wasserman, R.A.3
Nitiss, J.4
Wang, J.C.5
Andoh, T.6
-
43
-
-
0029847080
-
Mechanisms of cell killing by drugs that trap covalent complexes between DNA topoisomerases and DNA
-
Nitiss, J. L., and Wang, J. C. Mechanisms of cell killing by drugs that trap covalent complexes between DNA topoisomerases and DNA. Mol. Pharmacol., 50: 1095-1102, 1996.
-
(1996)
Mol. Pharmacol.
, vol.50
, pp. 1095-1102
-
-
Nitiss, J.L.1
Wang, J.C.2
-
44
-
-
0025133118
-
Involvement of nucleic acid synthesis in cell killing mechanisms of topoisomerase poisons
-
D'Arpa, P., Beardmore, C., and Liu, L. F. Involvement of nucleic acid synthesis in cell killing mechanisms of topoisomerase poisons. Cancer Res., 50: 6919-6924, 1990.
-
(1990)
Cancer Res.
, vol.50
, pp. 6919-6924
-
-
D'Arpa, P.1
Beardmore, C.2
Liu, L.F.3
-
45
-
-
0028567826
-
Doxorubicin, daunorubicin, and mitoxantrone cytotoxicity in yeast
-
published erratum appears in Mol. Pharmacol., 47: 882, 1995
-
Kule, C., Ondrejickova, O., and Verner, K. Doxorubicin, daunorubicin, and mitoxantrone cytotoxicity in yeast (published erratum appears in Mol. Pharmacol., 47: 882, 1995). Mol. Pharmacol., 46: 1234-1240, 1994.
-
(1994)
Mol. Pharmacol.
, vol.46
, pp. 1234-1240
-
-
Kule, C.1
Ondrejickova, O.2
Verner, K.3
-
46
-
-
0023221847
-
Markedly reduced levels of anthracycline-induced DNA strand breaks in resistant P388 leukemia cells and isolated nuclei
-
Capranico, G., Riva, A., Tinelli, S., Dasdia, T., and Zunino, F. Markedly reduced levels of anthracycline-induced DNA strand breaks in resistant P388 leukemia cells and isolated nuclei. Cancer Res., 47: 3752-3756, 1987.
-
(1987)
Cancer Res.
, vol.47
, pp. 3752-3756
-
-
Capranico, G.1
Riva, A.2
Tinelli, S.3
Dasdia, T.4
Zunino, F.5
-
47
-
-
0028070579
-
Using yeast to study resistance to topoisomerase II-targeting drugs
-
Nitiss, J. L. Using yeast to study resistance to topoisomerase II-targeting drugs. Cancer Chemother. Pharmacol., 34 (Suppl.): S6-S13, 1994.
-
(1994)
Cancer Chemother. Pharmacol.
, vol.34
, Issue.SUPPL.
-
-
Nitiss, J.L.1
-
48
-
-
0025334763
-
Differences between normal and ras-transformed NIH-3T3 cells in expression of the 170kD and 180kD forms of topoisomerase II
-
Woessner, R. D., Chung, T. D., Hofmann, G. A., Mattern, M. R., Mirabelli, C. K., Drake, F. H., and Johnson, R. K. Differences between normal and ras-transformed NIH-3T3 cells in expression of the 170kD and 180kD forms of topoisomerase II. Cancer Res., 50: 2901-2908, 1990.
-
(1990)
Cancer Res.
, vol.50
, pp. 2901-2908
-
-
Woessner, R.D.1
Chung, T.D.2
Hofmann, G.A.3
Mattern, M.R.4
Mirabelli, C.K.5
Drake, F.H.6
Johnson, R.K.7
-
49
-
-
0029612305
-
Differential expression of DNA topoisomerases in non-small cell lung cancer and normal lung. Biochim
-
Giaccone, G., van Ark-Otte, J., Scagliotti, G., Capranico, G., van der Valk, P., Rubio, G., Dalesio, O., Lopez, R., Zunino, F., Walboomers, J., and Pinedo, H. Differential expression of DNA topoisomerases in non-small cell lung cancer and normal lung. Biochim. Biophys. Acta, 1264: 337-346, 1995.
-
(1995)
Biophys. Acta
, vol.1264
, pp. 337-346
-
-
Giaccone, G.1
Van Ark-Otte, J.2
Scagliotti, G.3
Capranico, G.4
Van Der Valk, P.5
Rubio, G.6
Dalesio, O.7
Lopez, R.8
Zunino, F.9
Walboomers, J.10
Pinedo, H.11
-
50
-
-
0025124473
-
Comparison of DNA cleavage induced by etoposide and doxorubicin in two human small-cell lung cancer lines with different sensitivities to topoisomerase II inhibitors
-
Binaschi, M., Capranico, G., De Isabella, P., Mariani, M., Supino, R., Tinelli, S., and Zunino, F. Comparison of DNA cleavage induced by etoposide and doxorubicin in two human small-cell lung cancer lines with different sensitivities to topoisomerase II inhibitors. Int. J. Cancer, 45: 347-352, 1990.
-
(1990)
Int. J. Cancer
, vol.45
, pp. 347-352
-
-
Binaschi, M.1
Capranico, G.2
De Isabella, P.3
Mariani, M.4
Supino, R.5
Tinelli, S.6
Zunino, F.7
-
51
-
-
0029052276
-
MRP gene overexpression in a human doxorubicin-resistant SCLC cell line: Alterations in cellular pharmacokinetics and in pattern of cross-resistance
-
Binaschi, M., Supino, R., Gambetta, R. A., Giaccone, G., Prosperi, E., Capranico, G., Cataldo, I., and Zunino, F. MRP gene overexpression in a human doxorubicin-resistant SCLC cell line: alterations in cellular pharmacokinetics and in pattern of cross-resistance. Int. J. Cancer, 62: 84-89, 1995.
-
(1995)
Int. J. Cancer
, vol.62
, pp. 84-89
-
-
Binaschi, M.1
Supino, R.2
Gambetta, R.A.3
Giaccone, G.4
Prosperi, E.5
Capranico, G.6
Cataldo, I.7
Zunino, F.8
-
52
-
-
0022593183
-
Characterization of a doxorubicin-resistant murine melanoma line: Studies on cross-resistance and
-
Supino, R., Prosperi, E., Formelli, F., Mariani, M., and Parmiani, G. Characterization of a doxorubicin-resistant murine melanoma line: studies on cross-resistance and its circumvention. Br. J. Cancer, 54: 33-42, 1986.
-
(1986)
Br. J. Cancer
, vol.54
, pp. 33-42
-
-
Supino, R.1
Prosperi, E.2
Formelli, F.3
Mariani, M.4
Parmiani, G.5
Circumvention, I.6
|