메뉴 건너뛰기




Volumn 49, Issue 1, 1997, Pages 17-25

Towards defining a minimal functional domain for NTPase and RNA helicase activities of the hepatitis C virus NS3 protein

Author keywords

HCV; NS3; NTPasc; RNA helicase

Indexed keywords

HYBRID PROTEIN; NUCLEOSIDE TRIPHOSPHATASE; PROTEINASE; RNA HELICASE; VIRUS PROTEIN;

EID: 0342872087     PISSN: 01681702     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0168-1702(97)01452-4     Document Type: Article
Times cited : (32)

References (19)
  • 1
    • 0024509701 scopus 로고
    • Isolation of a cDNA clone derived from a blood borne Non-A, non-B viral hepatitis genome
    • Choo, Q.-L., Kuo, G., Weiner, A.J., Overby, L.R., Bradley, D.W. and Houghton, M. (1989) Isolation of a cDNA clone derived from a blood borne Non-A, non-B viral hepatitis genome. Science 244, 359-362.
    • (1989) Science , vol.244 , pp. 359-362
    • Choo, Q.-L.1    Kuo, G.2    Weiner, A.J.3    Overby, L.R.4    Bradley, D.W.5    Houghton, M.6
  • 3
    • 0028290579 scopus 로고
    • Both NS3 and NS4A are required for proteolytic processing of hepatitis C virus nonstructural proteins
    • Faila, C., Tomei, L. and de Francesco, R. (1994) Both NS3 and NS4A are required for proteolytic processing of hepatitis C virus nonstructural proteins. J. Virol. 68, 3753-3760.
    • (1994) J. Virol. , vol.68 , pp. 3753-3760
    • Faila, C.1    Tomei, L.2    De Francesco, R.3
  • 4
    • 0024344173 scopus 로고
    • Two related superfamilies of putative helicases involved in replication, recombination, repair and expression of DNA and RNA genomes
    • Gorbalenya, A.E., Koonin, E.V., Donchenko, A.P. and Blinov, V.M. (1989) Two related superfamilies of putative helicases involved in replication, recombination, repair and expression of DNA and RNA genomes. Nucleic Acids Res. 17, 4713-4729.
    • (1989) Nucleic Acids Res. , vol.17 , pp. 4713-4729
    • Gorbalenya, A.E.1    Koonin, E.V.2    Donchenko, A.P.3    Blinov, V.M.4
  • 5
    • 0029079703 scopus 로고
    • Mutational analysis of vaccinia virus nucleoside triphosphate phosphohydrolase II, a DExH box RNA helicase
    • Gross, C.H. and Shuman, S. (1995) Mutational analysis of vaccinia virus nucleoside triphosphate phosphohydrolase II, a DExH box RNA helicase. J. Virol. 69, 4727-4736.
    • (1995) J. Virol. , vol.69 , pp. 4727-4736
    • Gross, C.H.1    Shuman, S.2
  • 6
    • 0030583249 scopus 로고    scopus 로고
    • Characterization of RNA binding activity and RNA helicase activity of the hepatitis C virus NS3 protein
    • Gwack, Y., Kim, D.W., Han, J.H. and Choe, J. (1996) Characterization of RNA binding activity and RNA helicase activity of the hepatitis C virus NS3 protein. Biochem. Biophy. Res. Commun. 225, 654-659.
    • (1996) Biochem. Biophy. Res. Commun. , vol.225 , pp. 654-659
    • Gwack, Y.1    Kim, D.W.2    Han, J.H.3    Choe, J.4
  • 7
    • 0026071871 scopus 로고
    • Characterization of terminal regions of hepatitis C viral RNA: Identification of conserved sequences in the 5′-untranslated region and poly(A) tails at the 3′-end
    • Han, J.H., Shyamala, K., Richman, K.H., Grauer, M.J., Irvine, B., Urdea, M.S., Tekamp-Olson, D., Kuo, G., Choo, Q.-L. and Houghton, M. (1991) Characterization of terminal regions of hepatitis C viral RNA: identification of conserved sequences in the 5′-untranslated region and poly(A) tails at the 3′-end. Proc. Natl. Acad. Sci. USA 88, 1711-1715.
    • (1991) Proc. Natl. Acad. Sci. USA , vol.88 , pp. 1711-1715
    • Han, J.H.1    Shyamala, K.2    Richman, K.H.3    Grauer, M.J.4    Irvine, B.5    Urdea, M.S.6    Tekamp-Olson, D.7    Kuo, G.8    Choo, Q.-L.9    Houghton, M.10
  • 8
    • 0026652903 scopus 로고
    • Group specific sequences and conserved secondary structures at the 3′-end of HCV genome and its implication for viral replication
    • Han, J.H. and Houghton, M. (1992) Group specific sequences and conserved secondary structures at the 3′-end of HCV genome and its implication for viral replication. Nucleic Acids Res. 20, 3520.
    • (1992) Nucleic Acids Res. , vol.20 , pp. 3520
    • Han, J.H.1    Houghton, M.2
  • 9
    • 0028800155 scopus 로고
    • Poly(U) binding activity of hepatitis C virus NS3 protein, a putative RNA helicase
    • Kanai, A., Tanabe, K. and Kohara, M. (1995) Poly(U) binding activity of hepatitis C virus NS3 protein, a putative RNA helicase. FEBS Lett. 376, 221-224.
    • (1995) FEBS Lett. , vol.376 , pp. 221-224
    • Kanai, A.1    Tanabe, K.2    Kohara, M.3
  • 10
    • 0028817781 scopus 로고
    • C′-terminal domain of the hepatitis C virus NS3 protein contains an RNA helicase activity
    • Kim, D.W., Gwack, Y., Han, J.H. and Choe, J. (1995) C′-terminal domain of the hepatitis C virus NS3 protein contains an RNA helicase activity. Biochem. Biophys. Res. Commun. 215, 160-166.
    • (1995) Biochem. Biophys. Res. Commun. , vol.215 , pp. 160-166
    • Kim, D.W.1    Gwack, Y.2    Han, J.H.3    Choe, J.4
  • 11
    • 0026726096 scopus 로고
    • A new RNA helicase isolated from HeLa cells that catalytically translocates in the 3′ to 5′ direction
    • Lee, C.-G. and Hurwitz, J. (1992) A new RNA helicase isolated from HeLa cells that catalytically translocates in the 3′ to 5′ direction. J. Biol. Chem. 267, 4398-4407.
    • (1992) J. Biol. Chem. , vol.267 , pp. 4398-4407
    • Lee, C.-G.1    Hurwitz, J.2
  • 12
    • 0026680746 scopus 로고
    • Mutational analysis of a DEAD box RNA helicase: The mammalian translation initiation factor eIF-4A
    • Pause, A. and Sonenberg, N. (1992) Mutational analysis of a DEAD box RNA helicase: the mammalian translation initiation factor eIF-4A. EMBO J. 11, 2643-2654.
    • (1992) EMBO J. , vol.11 , pp. 2643-2654
    • Pause, A.1    Sonenberg, N.2
  • 13
    • 0029076837 scopus 로고
    • The N′-terminal region of hepatitis C virus nonstructural protein 3 (NS3) is essential for stable complex formation with NS4A
    • Satoh, S., Tanji, Y., Hijikata, M., Kimura, K. and Shimotohno, K. (1995) The N′-terminal region of hepatitis C virus nonstructural protein 3 (NS3) is essential for stable complex formation with NS4A. J. Virol. 69, 4255-4260.
    • (1995) J. Virol. , vol.69 , pp. 4255-4260
    • Satoh, S.1    Tanji, Y.2    Hijikata, M.3    Kimura, K.4    Shimotohno, K.5
  • 14
    • 0027199917 scopus 로고
    • Hepatitis C virus NS3 protein polynucleotide-stimulated nucleoside triphosphatase and comparison with the related pestivirus and Flavivirus enzymes
    • M.
    • Suzich, J.A., Tamura, J.K., Palmer-Hill, F., Warrener, P., Grakoui, A., Rice, C.M., Feinstone, S.,M. and Collett, M.S. (1993) Hepatitis C virus NS3 protein polynucleotide-stimulated nucleoside triphosphatase and comparison with the related pestivirus and Flavivirus enzymes. J. Virol. 67, 6152-6158.
    • (1993) J. Virol. , vol.67 , pp. 6152-6158
    • Suzich, J.A.1    Tamura, J.K.2    Palmer-Hill, F.3    Warrener, P.4    Grakoui, A.5    Rice, C.M.6    Feinstone, S.7    Collett, M.S.8
  • 15
    • 0027254336 scopus 로고
    • RNA-stimulated NTPase activity associated with te p80 protein of the pestivirus bovine viral diarrhea virus
    • Tamura, J.K., Warrener, P. and Collett, M.S. (1993) RNA-stimulated NTPase activity associated with te p80 protein of the pestivirus bovine viral diarrhea virus. Virology 193, 1-10.
    • (1993) Virology , vol.193 , pp. 1-10
    • Tamura, J.K.1    Warrener, P.2    Collett, M.S.3
  • 16
    • 0027176287 scopus 로고
    • NS3 is a serine protease required for processing of hepatitis C virus polyprotein
    • Tomei, L., Failla, C., Santolini, E., de Francesco, R. and La Monica, N. (1993) NS3 is a serine protease required for processing of hepatitis C virus polyprotein. J. Virol. 67, 4017-4026.
    • (1993) J. Virol. , vol.67 , pp. 4017-4026
    • Tomei, L.1    Failla, C.2    Santolini, E.3    De Francesco, R.4    La Monica, N.5
  • 17
    • 0028872259 scopus 로고
    • Pestivirus NS3 (p80) protein possesses RNA helicase activity
    • Warrener, P. and Collett M.S. (1995) Pestivirus NS3 (p80) protein possesses RNA helicase activity. J. Virol. 69, 1720-1726.
    • (1995) J. Virol. , vol.69 , pp. 1720-1726
    • Warrener, P.1    Collett, M.S.2
  • 18
    • 0025945616 scopus 로고
    • The carboxy-terminal part of the NS3 protein of the West Nile Flavivirus can be isolated as a soluble protein after proteolytic cleavage and represents an RNA-stimulated NTPase
    • Wengler, G. and Wengler, G. (1991) The carboxy-terminal part of the NS3 protein of the West Nile Flavivirus can be isolated as a soluble protein after proteolytic cleavage and represents an RNA-stimulated NTPase. Virology 184, 707-715.
    • (1991) Virology , vol.184 , pp. 707-715
    • Wengler, G.1    Wengler, G.2
  • 19
    • 0028961384 scopus 로고
    • Transfection of a differentiated human hepatoma cell line (Huh7) with in vitro-transcribed hepatitis C virus (HCV) RNA and establishment of a long-term culture persistently infected with HCV
    • Yoo, B.J., Selby, M.J., Choe, J., Suh, B.S., Choi, S.H., Joh, J.S., Nuovo, G.J., Lee, H., Houghton, M. and Han, J.H. (1995) Transfection of a differentiated human hepatoma cell line (Huh7) with in vitro-transcribed hepatitis C virus (HCV) RNA and establishment of a long-term culture persistently infected with HCV. J. Virol. 69, 32-38.
    • (1995) J. Virol. , vol.69 , pp. 32-38
    • Yoo, B.J.1    Selby, M.J.2    Choe, J.3    Suh, B.S.4    Choi, S.H.5    Joh, J.S.6    Nuovo, G.J.7    Lee, H.8    Houghton, M.9    Han, J.H.10


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.