Expression of 11β-hydroxysteroid dehydrogenase in early pregnancy: Implications in human trophoblast-endometrial interactions

Seminars in Reproductive Endocrinology

Volumn 17, Issue 1, 1999, Pages 53-61

  Arcuri, Felice ^a   Sestini, Silvia ^a   Cintorino, Marcella ^a  

^a UNIVERSITY OF SIENA   (Italy)

Author keywords

Decidua; Glucocorticoid metabolism; Placenta; Trophoblasts

Indexed keywords

11BETA HYDROXYSTEROID DEHYDROGENASE; CORTICOSTERONE; CORTISONE; DEHYDROCORTICOSTERONE; GLUCOCORTICOID; HYDROCORTISONE; ISOENZYME;

CONFERENCE PAPER; CONTROLLED STUDY; CORTICOSTEROID METABOLISM; DECIDUALIZATION; ENDOMETRIUM; ENZYME ACTIVITY; FEMALE; FETOPLACENTAL UNIT; FIRST TRIMESTER PREGNANCY; HUMAN; HUMAN CELL; NIDATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; STROMA CELL; SYNCYTIOTROPHOBLAST; TROPHOBLAST;

EID: 0033050197     PISSN: 07348630     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-2007-1016212     Document Type: Conference Paper

References (63)

1. Amelung D, Huebener HJ, Roka L, Meyerheim G. Conversion of cortisone to compound F. J Clin Endocrinol Metab 1953;13:1125
2. Lakshmi V, Monder C. Purification and characterization of the corticosteroid 11 beta-dehydrogenase component of the rat liver 11 beta-hydroxysteroid dehydrogenase complex. Endocrinology 1988;123:2390-2398
3. Agarwal AK, Monder C, Eckstein B, White PC. Cloning and expression of rat cDNA encoding corticosteroid 11 beta- dehydrogenase. J Biol Chem 1989;264:18939-18943
4. Tannin GM, Agarwal AK, Monder C, New MI, White PC. The human gene for 11 beta-hydroxysteroid dehydrogenase: Structure, tissue distribution, and chromosomal localization. J Biol Chem 1991;266:16653-16658
5. Yang K, Smith CL, Dales D, Hammond GL, Challis JR. Cloning of an ovine 11 beta-hydroxysteroid dehydrogenase complementary deoxyribonucleic acid: Tissue and temporal distribution of its messenger ribonucleic acid during fetal and neonatal development. Endocrinology 1992;131:2120-2126
6. Rajan V, Chapman KE, Lyons V, Jamieson P, Mullins JJ, Edwards CR, Seckl JR. Cloning, sequencing and tissue-distribution of mouse 11 beta- hydroxysteroid dehydrogenase-1 cDNA. J Steroid Biochem Mol Biol 1995;52:141-147
7. Brown RW, Chapman KE, Edwards CR, Seckl JR. Human placental 11 beta-hydroxysteroid dehydrogenase: Evidence for and partial purification of a distinct NAD-dependent isoform. Endocrinology 1993;132:2614-2621
8. Rusvai E, Naray-Fejes-Toth A. A new isoform of 11 beta-hydroxysteroid dehydrogenase in aldosterone target cells. J Biol Chem 1993;268:10717-10720
9. Albiston AL, Obeyesekere VR, Smith RE, Krozowski ZS. Cloning and tissue distribution of the human 11 beta-hydroxysteroid dehydrogenase type 2 enzyme. Mol Cell Endocrinol 1994;105:R11-R17
10. Agarwal AK, Mune T, Monder C, White PC. NAD(+)-dependent isoform of 11 beta-hydroxysteroid dehydrogenase. Cloning and characterization of cDNA from sheep kidney. J Biol Chem 1994;269:25959-25962
11. Monder C, Lakshmi V. Corticosteroid 11 beta-dehydrogenase of rat tissues: Immunological studies. Endocrinology 1990;126:2435-2443
12. Ricketts ML, Verhaeg JM, Bujalska I, Howie AJ, Rainey WE, Stewart PM. Immunohistochemical localization of type 1 11beta-hydroxysteroid dehydrogenase in human tissues. J Clin Endocrinol Metab 1998;83:1325-1335
13. Li KX, Obeyesekere VR, Krozowski ZS, Ferrari P. Oxoreductase and dehydrogenase activities of the human and rat 11beta- hydroxysteroid dehydrogenase type 2 enzyme. Endocrinology 1997;138:2948-2952
14. Monder C, White PC. 11 beta-hydroxysteroid dehydrogenase. Vitam Horm 1993;47:187-271
15. Stewart PM, Whorwood CB, Mason JI. Type 2 11 beta-hydroxysteroid dehydrogenase in foetal and adult life. J Steroid Biochem Mol Biol 1995;55:465-171
16. Mune T, Rogerson FM, Nikkila H, Agarwal AK, White PC. Human hypertension caused by mutations in the kidney isozyme of 11 beta- hydroxysteroid dehydrogenase. Nat Genet 1995;10:394-399
17. Wilson RC, Harbison MD, Krozowski ZS, Funder JW, Shackleton CH, Hanauske-Abel HM, Wei JQ, Hertecant J, Moran A, Neiberger RE, et al. Several homozygous mutations in the gene for 11 beta-hydroxysteroid dehydrogenase type 2 in patients with apparent mineralocorticoid excess. J Clin Endocrinol Metab 1995;80:3145-3150
18. Roland BL, Funder JW. Localization of 11beta-hydroxysteroid dehydrogenase type 2 in rat tissues: In situ studies. Endocrinology 1996;137:1123-1128
19. Smith RE, Salamonsen LA, Komesaroff PA, Li KX, Myles KM, Lawrence M, Krozowski Z. 11 beta-Hydroxysteroid dehydrogenase type II in the human endometrium: Localization and activity during the menstrual cycle. J Clin Endocrinol Metab 1997;82:4252-4257
20. Osinski PA. Steroid 11 beta-dehydrogenase in human placenta. Nature 1960;187:777
21. Murphy BE, Clark SJ, Donald IR, Pinsky M, Vedady D. Conversion of maternal cortisol to cortisone during placental transfer to the human fetus. Am J Obstet Gynecol 1974;118:538-541
22. Levitz M, Jansen V, Dancis J. The transfer and metabolism of corticosteroids in the perfused human placenta. Am J Obstet Gynecol 1978;132:363-366
23. Baird CW, Bush IE. Cortisol and cortisone content of amniotic fluid from diabetic and non diabetic women. Acta Endocrinol 1960;34:97-104
24. Bro-Rasmussen F, Buus O, Trolle D. Ratio of cortisone/cortisol in mother and infant at birth. Acta Endocrinol 1962;40:579-583
25. Reinisch JM, Simon NG, Karow WG, Gandelman R. Prenatal exposure to prednisone in humans and animals retards intrauterine growth. Science 1978;202:436-438
26. Graf R, Gossrau R, Frank HG. Placental toxicity in rats after administration of synthetic glucocorticoids: A morphological, histochemical and immunohistochemical investigation. Anat Embryol 1989;180:121-130
27. Barker DJ, Osmond C, Golding J, Kuh D, Wadsworth ME. Growth in utero, blood pressure in childhood and adult life, and mortality from cardiovascular disease. BMJ 1989;298:564-567
28. Benediktsson R, Lindsay RS, Noble J, Seckl JR, Edwards CR. Glucocorticoid exposure in utero: New model for adult hypertension. Lancet 1993;341:339-341
29. Langley-Evans SC, Phillips GJ, Benediktsson R, Gardner DS, Edwards CR, Jackson AA, Seckl JR. Protein intake in pregnancy, placental glucocorticoid metabolism and the programming of hypertension in the rat. Placenta 1996;17:169-172
30. Lakshmi V, Nath N, Muneyyirci-Delale O. Characterization of 11 beta-hydroxysteroid dehydrogenase of human placenta: Evidence for the existence of two species of 11 beta-hydroxysteroid dehydrogenase. J Steroid Biochem Mol Biol 1993;45:391-397
31. Krozowski Z, MaGuire JA, Stein-Oakley AN, Dowling J, Smith RE, Andrews RK. Immunohistochemical localization of the 11 beta-hydroxysteroid dehydrogenase type II enzyme in human kidney and placenta. J Clin Endocrinol Metab 1995;80:2203-2209
32. Stewart PM, Rogerson FM, Mason JI. Type 2 11 beta-hydroxysteroid dehydrogenase messenger ribonucleic acid and activity in human placenta and fetal membranes: Its relationship to birth weight and putative role in fetal adrenal steroidogenesis. J Clin Endocrinol Metab 1995;80:885-890
33. Sun K, Yang K, Challis JR. Differential expression of 11 beta-hydroxysteroid dehydrogenase types 1 and 2 in human placenta and fetal membranes. J Clin Endocrinol Metab 1997;82:300-305
34. Lockwood CJ, Nemerson Y, Guller S, Krikun G, Alvarez M, Hausknecht V, Gurpide E, Schatz F. Progestational regulation of human endometrial stromal cell tissue factor expression during decidualization. J Clin Endocrinol Metab 1993;76:231-236
35. Huang JR, Tseng L, Bischof P, Janne OA. Regulation of prolactin production by progestin, estrogen, and relaxin in human endometrial stromal cells. Endocrinology 1987;121:2011-2017
36. Irwin JC, Kirk D, King RJ, Quigley MM, Gwatkin RB. Hormonal regulation of human endometrial stromal cells in culture: An in vitro model for decidualization. Fertil Steril 1989;52:761-768
37. Zhu HH, Huang JR, Mazela J, Elias J, Tseng L. Progestin stimulates the biosynthesis of fibronectin and accumulation of fibronectin mRNA in human endometrial stromal cells. Hum Reprod 1992;7:141-146
38. Lockwood CJ, Nemerson Y, Krikun G, Hausknecht V, Markiewicz L, Alvarez M, Guller S, Schatz F. Steroid-modulated stromal cell tissue factor expression: A model for the regulation of endometrial hemostasis and menstruation. J Clin Endocrinol Metab 1993,77:1014-1019
39. Schatz F, Papp C, Toth-Pal E, Lockwood CJ. Ovarian steroid-modulated stromelysin-1 expression in human endometrial stromal and decidual cells. J Clin Endocrinol Metab 1994;78:1467-1472
40. Schatz F, Aigner S, Papp C, Toth-Pal E, Hausknecht V, Lockwood CJ. Plasminogen activator activity during decidualization of human endometrial stromal cells is regulated by plasminogen activator inhibitor 1. J Clin Endocrinol Metab 1995;80:2504-2510
41. Arcuri F, Monder C, Lockwood CJ, Schatz F. Expression of 11 beta-hydroxysteroid dehydrogenase during decidualization of human endometrial stromal cells. Endocrinology 1996;137:595-600
42. Arcuri F, Sestini S, Paulesu L, Bracci L, Carducci A, Manzoni F, Cardone C, Cintorino M. 11 Beta-hydroxysteroid dehydrogenase expression in first trimester human trophoblasts. Mol Cell Endocrinol 1998;141:13-20
43. Bernal AL, Flint AP, Anderson AB, Turnbull AC. 11 beta-Hydroxyteroid dehydrogenase activity (E.G. 1.1.1.146) in human placenta and decidua. J Steroid Biochem 1980;13:1081-1087
44. Giannopoulos G, Jackson K, Tulchinsky D. Glucocorticoid metabolism in human placenta, decidua, myometrium and fetal membranes. J Steroid Biochem 1982;17:371-374
45. Eckert RL, Katzenellenbogen BS. Human endometrial cells in primary tissue culture: Modulation of the progesterone receptor level by natural and synthetic estrogens in vitro. J Clin Endocrinol Metab 1981;52:699-708
46. Funkhouser JD, Peevy KJ, Mockridge PB, Hughes ER. Distribution of dexamethasone between mother and fetus after maternal administration. Pediatr Res 1978;12:1053-1056
47. Brown RW, Chapman KE, Kotelevtsev Y, Yau JL, Lindsay RS, Brett L, Leckie C, Murad P, Lyons V, Mullins JJ, Edwards CR, Seckl JR. Cloning and production of antisera to human placental 11 beta- hydroxysteroid dehydrogenase type 2. Biochem J 1996;313:1007-1017
48. Monder C, Miroff Y, Marandici A, Hardy MP. 11 beta-Hydroxysteroid dehydrogenase alleviates glucocorticoid-mediated inhibition of steroidogenesis in rat Leydig cells. Endocrinology 1994;134:1199-1204
49. Benediktsson R, Calder AA, Edwards CR, Seckl JR. Placental 11 beta-hydroxysteroid dehydrogenase: A key regulator of fetal glucocorticoid exposure. Clin Endocrinol (Oxf) 1997;46:161-166
50. Hundertmark S, Buhler H, Rudolf M, Weitzel HK, Ragosch V. Inhibition of 11 beta-hydroxysteroid dehydrogenase activity enhances the antiproliferative effect of glucocorticosteroids on MCF-7 and ZR-75-1 breast cancer cells. J Endocrinol 1997;155:171-180
51. Johnson DC, Dey SK. Role of histamine in implantation: Dexamethasone inhibits estradiol-induced implantation in the rat. Biol Reprod 1980;22:1136-1141
52. Hicks JJ, Duran-Reyes G, Diaz-Flores M. Effect of dexamethasone as an inhibitor of implantation and embryo development in rat; lysosomal role. Contraception 1994;50:581-589
53. Jacobs AL, Hwang D, Julian J, Carson DD. Regulated expression of prostaglandin endoperoxide synthase-2 by uterine stroma. Endocrinology 1994;135:1807-1815
54. Tchernitchin A, Rooryck J, Tchernitchin X, Vandenhende J, Galand P. Effects of cortisol on uterine eosinophilia and other oestrogenic responses. Mol Cell Endocrinol 1975;2:331-337
55. Chard T. Cytokines in implantation. Hum Reprod Update 1995;1:385-396
56. Tang B, Guller S, Gurpide E. Mechanism of human endometrial stromal cells decidualization. Ann NY Acad Sci 1994,734:19-25
57. Bennett WA, Lagoo-Deenadayalan S, Brackin MN, Hale E, Cowan BD. Cytokine expression by models of human trophoblast as assessed by a semiquantitative reverse transcription-polymerase chain reaction technique. Am J Reprod Immunol 1996;36:285-294
58. Munck A, Naray-Fejes-Toth A. Glucocorticoids and stress: Permissive and suppressive actions. Ann N Y Acad Sci 1994;746:115-130
59. Cato AC, Wade E. Molecular mechanisms of anti-inflammatory action of glucocorticoids. Bioessays 1996;18:371-378
60. Librach CL, Feigenbaum SL, Bass KE, Cui TY, Verastas N, Sadovsky Y, Quigley JP, French DL, Fisher SJ. Interleukin-1 beta regulates human cytotrophoblast metalloproteinase activity and invasion in vitro. J Biol Chem 1994;269:17125-17131
61. Rosen T, Krikun G, Ma Y, Wang EY, Lockwood CJ, Guller S. Chronic antagonism of nuclear factor-kappaB activity in cytotrophoblasts by dexamethasone: A potential mechanism for antiinflammatory action of glucocorticoids in human placenta. J Clin Endocrinol Metab 1998;83:3647-3652
62. Mignatti P, Rifkin DB. Biology and biochemistry of proteinases in tumor invasion. Physiol Rev 1993;73:161-195
63. Guller S, Wozniak R, Krikun G, Burnham JM, Kaplan P, Lockwood CJ. Glucocorticoid suppression of human placental fibronectin expression: Implications in uterine-placental adherence. Endocrinology 1993;133:1139-1146