Protein intake in pregnancy, placental glucocorticoid metabolism and the programming of hypertension in the rat

Placenta

Volumn 17, Issue 2-3, 1996, Pages 169-172

  Langley Evans, S C ^a   Phillips, G J ^a   Benediktsson, R ^a   Gardner, D S ^a   Edwards, C R W ^a   Jackson, A A ^a   Seckl, J R ^a  

^a UNIVERSITY OF SOUTHAMPTON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

11BETA HYDROXYSTEROID DEHYDROGENASE; CASEIN; GLUCOCORTICOID; GLUTAMATE AMMONIA LIGASE; PLACENTA ENZYME;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BIRTH WEIGHT; CALORIC INTAKE; CONTROLLED STUDY; CORTICOSTEROID METABOLISM; ENZYME ACTIVITY; FEMALE; FETUS GROWTH; HYPERTENSION; MALE; MALNUTRITION; MATERNAL NUTRITION; NEWBORN; NONHUMAN; PLACENTA DEVELOPMENT; PLACENTA WEIGHT; PRIORITY JOURNAL; PROTEIN INTAKE; RAT; STEROID METABOLISM; SYSTOLIC BLOOD PRESSURE;

EID: 0029912988     PISSN: 01434004     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0143-4004(96)80010-5     Document Type: Article

References (18)

1. Albiston A.L. Obeyesekere V.R. Smith R.E. Krozowski Z.S. Cloning and tissue distribution of the human 11β-hydroxysteroid dehydrogenase type 2 enzyme Molecular and Cellular Endocrinology 105 1994 R11 R17
2. Arai Y. Gorski R.A. Critical exposure time for androgenization of the developing hypothalamus in the female rat Endocrinology 82 1968 1010 1014
3. Barker D.J.P. Fetal and Infant Origins of Adult Disease 1991 BMJ Books London
4. Barker D.J.P. Gluckman P.D. Godfrey K.M. Harding J.E. Owens J.A. Robinson J.S. Fetal nutrition and cardiovascular disease in adult life Lancet 341 1993 938 941
5. Benediktsson R. Lindsay R.S. Noble J. Seckl J.R. Edwards C.R.W. Glucocorticoid exposure in utero: new model for adult hypertension Lancet 341 1993 339 341
6. Edwards C.R.W. Benediktsson R. Lindsay R. Seckl J.R. Dysfunction of the placental glucocorticoid barrier: a link between the foetal environment and adult hypertension? Lancet 341 1993 355 357
7. Langley S.C. York D.A. Increased type II-glucocorticoid receptor numbers and glucocorticoid-sensitive enzyme activities in the brain of the obese Zucker rat Brain Research 533 1990 268 274
8. Langley S.C. Jackson A.A. Increased systolic blood pressure in adult rats, induced by fetal exposure to maternal low protein diets Clinical Science 86 1994 217 222
9. Langley-Evans S.C. Early life origins of hypertension: a rat model British Nutrition Foundation Bulletin 19 Suppl. 1994 69 77
10. Langley-Evans S.C. Phillips G.J. Jackson A.A. In utero exposure to maternal low protein diets induces hypertension in weaning rats, independently of maternal blood pressure changes Clinical Nutrition 13 1994 319 324
11. Lindsay R.S. Noble J.M. Edwards C.R.W. Seckl J.R. Maternal carbenoxolone treatment reduces birthweight in the rat Journal of Endocrinology 140 suppl 1994 18
12. Meaney M.J. Aitken D.H. Sharma S. Viau V. Basal ACTH, corticosterone and corticosterone binding globulin levels over the diurnal cycle, and hippocampal corticosteroid receptors in young and aged, handled or non-handled rats Neuroendocrinology 55 1992 204 213
13. Nebert D.W. Genetic differences in microsomal electron transport: the Ah locus Methods in Enzymology 52 1979 226 240
14. Nelson M.M. Evans H.M. Relation of dietary protein levels to reproduction in the rat Journal of Nutrition 51 1953 71 84
15. Reinisch J.M. Simon N.G. Karow W.G. Gandleman R. Prenatal exposure to prednisone in humans and animals retards intrauterine growth Science 202 1978 436 438
16. Seckl J.R. Brown R.W. 11β-hydroxysteroid dehydrogenase: on several roads to hypertension Journal of Hypertension 12 1994 105 112
17. Tangalakis K. Lumbers E.R. Moritz K.M. Towstoless M.K. Wintour E.M. Effect of cortisol on blood pressure and vascular reactivity in the ovine fetus Experimental Physiology 77 1992 709 717
18. Zhou M.Y. Gomez Sanchez E.P. Cox D.L. Cosby D. Gomez Sanchez C.E. Cloning, expression and tissue distribution of the rat nicotinamide adenine dinucleotide-dependent 11β-hydroxysteroid dehydrogenase Endocrinology 136 1995 3729 3734