Association of CTLA-4 gene A-G polymorphism (IDDM12 locus) with acute- onset and insulin-depleted IDDM as well as autoimmune thyroid disease (Graves' disease and Hashimoto's thyroiditis) in the Japanese population

Diabetes

Volumn 47, Issue 1, 1998, Pages 128-129

  Awata, Takuya ^a   Kurihara, Susumu ^a   Iitaka, Makoto ^a   Takei, Shin Ichiro ^a   Inoue, Ikuo ^a   Ishii, Chikara ^a   Negishi, Kiyohiko ^a   Izumida, Taro ^a   Yoshida, Yoko ^b   Hagura, Ryoko ^b   Kuzuya, Nobuaki ^c   Kanazawa, Yasunori ^c   Katayama, Shigehiro ^a  

^a SAITAMA MEDICAL UNIVERSITY   (Japan)

^b INSTITUTE FOR ADULT DISEASES   (Japan)

^c JICHI MEDICAL UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ADOLESCENT; ADULT; AGED; ARTICLE; AUTOIMMUNITY; CHILD; GENE FREQUENCY; GENE LOCUS; GENETIC ASSOCIATION; GENETIC POLYMORPHISM; GENOTYPE; GRAVES DISEASE; HASHIMOTO DISEASE; HUMAN; HUMAN CELL; HUMAN TISSUE; INFANT; INSULIN DEPENDENT DIABETES MELLITUS; INSULIN METABOLISM; JAPAN; MAJOR CLINICAL STUDY; PRIORITY JOURNAL;

EID: 0031975367     PISSN: 00121797     EISSN: None     Source Type: Journal    
DOI: 10.2337/diab.47.1.128     Document Type: Article

References (10)

1. Todd JA: Genetic analysis of type 1 diabetes using whole genome approaches. Proc Natl Acad Sci USA 92:8560-8565, 1995
2. Tomer Y, Barbesino G, Keddache M, Greenberg DA, Davies TF: Mapping of a major susceptibility locus for Graves' disease (GD-1) to chromosome 14q31. J Clin Endocrinol Metab 82:1645-1648, 1997
3. Yanagawa T, Hidaka Y, Guimaraes V, Soliman M, DeGroot LJ: CTLA-4 gene polymorphism associated with Graves' disease in a Caucasian population. J Clin Endocrinol Metab 80:41-45, 1995
4. Nistico L, Buzzetti R, Pritchard LE, Van der Auwera B, Giovannini C, Bosi E, Larrad MTM, Rios MS, Chow CC, Cockram CS, Jacobs K, Mijovic C, Bain SC, Barnett AH, Vandewalle CL, Schuit F, Gorus FK, Tosi R, Pozzilli P, Todd JA: The CTLA-4 gene region of chromosome 2q33 is linked to, and associated with, type 1 diabetes. Hum Mol Genet 5:1075-1080, 1996
5. Donner H, Rau H, Walfish PG, Braun J, Siegmund T, Finke R, Herwig J, Usadel KH, Badenhoop K: CTLA4 alanine-17 confers genetic susceptibility to Graves' disease and to type 1 diabetes mellitus. J Clin Endocrinol Metab 82:143-146, 1997
6. Waterhouse P, Marengere LEM, Mittrucker H-L, Mak TW: CTLA-4, a negative regulator of T-lymphocyte activation. Immunol Rev 153:183-207, 1996
7. Awata T, Kuzuya T, Matsuda A, Iwamoto Y, Kanazawa Y: Genetic analysis of HLA class II alleles and susceptibility to type 1 (insulin-dependent) diabetes mellitus in Japanese subjects. Diabetologia 35:419-424, 1992
8. Awata T, Kurihara S, Kikuchi C, Takei S, Inoue I, Ishii C, Takahashi K, Negishi K, Yoshida Y, Hagura R, Kanazawa Y, Katayama S: Evidence for association between the class 1 subset of insulin gene minisatellite (IDDM2 locus) and IDDM in the Japanese population. Diabetes 46:1637-1642, 1997
9. Kobayashi T, Tamemoto K, Nakanishi K, Kato N, Okubo M, Kajio H, Sugimoto T, Murase T, Kosaka K: Immunogenetic and clinical characterization of slowly progressive IDDM. Diabetes Care 16:780-788, 1993
10. Nakanishi K, Kobayashi T, Murase T, Nakatsuji T, Inoko H, Tsuji K, Kosaka K Association of HLA-A24 with complete β-cell destruction in IDDM. Diabetes 42:1086-1093, 1993