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Volumn 6, Issue 6, 1999, Pages 994-1005

Liposome-mediated NGF gene transfection following neuronal injury: Potential therapeutic applications

Author keywords

ChAT; CNS; Gene therapy; Liposomes; Neuronal injury; NGF

Indexed keywords

CATION; CHOLESTEROL; LIPOSOME; MESSENGER RNA; NERVE GROWTH FACTOR; NEUROTROPHIC FACTOR;

EID: 0033020604     PISSN: 09697128     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.gt.3300936     Document Type: Article
Times cited : (61)

References (64)
  • 1
    • 0022486717 scopus 로고
    • Nerve growth factor promotes survival of septal cholinergic neurons after fimbrial transactions
    • Hefti F. Nerve growth factor promotes survival of septal cholinergic neurons after fimbrial transactions. J Neurosci 1986; 8: 2155-2162.
    • (1986) J Neurosci , vol.8 , pp. 2155-2162
    • Hefti, F.1
  • 2
    • 0023067115 scopus 로고
    • Nerve growth factor treatment after brain injury prevents neuronal death
    • Kromer LF. Nerve growth factor treatment after brain injury prevents neuronal death. Science 1987; 235: 214-216.
    • (1987) Science , vol.235 , pp. 214-216
    • Kromer, L.F.1
  • 3
    • 0001641539 scopus 로고
    • Continuous infusion of nerve growth factor prevents basal forebrain neuronal death after fimbria-fornix transection
    • Williams LR et al. Continuous infusion of nerve growth factor prevents basal forebrain neuronal death after fimbria-fornix transection. Proc Natl Acad Sci USA 1986; 83: 9231-9235.
    • (1986) Proc Natl Acad Sci USA , vol.83 , pp. 9231-9235
    • Williams, L.R.1
  • 4
    • 0024263047 scopus 로고
    • Grafting genetically modified cells to the damaged brain: Restorative effects of NGF expression
    • Rosenberg MB et al. Grafting genetically modified cells to the damaged brain: restorative effects of NGF expression. Science 1988; 242: 1575-1578.
    • (1988) Science , vol.242 , pp. 1575-1578
    • Rosenberg, M.B.1
  • 5
    • 0027404330 scopus 로고
    • Neurotropism of nerve growth factor for adult rat septal cholinergic axons in vivo
    • Hagg T, Varon S. Neurotropism of nerve growth factor for adult rat septal cholinergic axons in vivo. Exp Neurol 1993; 119: 37-45.
    • (1993) Exp Neurol , vol.119 , pp. 37-45
    • Hagg, T.1    Varon, S.2
  • 6
    • 0025938955 scopus 로고
    • NGF improves spatial memory in aged rodents as a function of age
    • Fischer W, Bjorklund A, Chen K, Gage FH. NGF improves spatial memory in aged rodents as a function of age. J Neurosci 1991; 11: 1889-1906.
    • (1991) J Neurosci , vol.11 , pp. 1889-1906
    • Fischer, W.1    Bjorklund, A.2    Chen, K.3    Gage, F.H.4
  • 7
    • 0026050828 scopus 로고
    • Loss of AchE and NGFr-labeling precedes neuronal death of axotomized septodiagonal band neurons: Reversal by intraventricular NGF infusion
    • Fischer W, Bjorklund A. Loss of AchE and NGFr-labeling precedes neuronal death of axotomized septodiagonal band neurons: reversal by intraventricular NGF infusion. Exp Neurol 1991; 113: 93-108.
    • (1991) Exp Neurol , vol.113 , pp. 93-108
    • Fischer, W.1    Bjorklund, A.2
  • 8
    • 0027178807 scopus 로고
    • Acetylcholine synthesis and release following continuous intracerebral administration of NGF in adult and aged Fischer-344 rats
    • Rylett RJ, Goddard S, Schmidt BM, Williams LR. Acetylcholine synthesis and release following continuous intracerebral administration of NGF in adult and aged Fischer-344 rats. J Neurosci 1993; 13: 3956-3963.
    • (1993) J Neurosci , vol.13 , pp. 3956-3963
    • Rylett, R.J.1    Goddard, S.2    Schmidt, B.M.3    Williams, L.R.4
  • 9
    • 0026654156 scopus 로고
    • Effect of delayed treatment with nerve growth factor on choline acetyltransferase activity in the cortex of rats with lesions of the nucleus basalis magnocellularis: Dose requirements
    • Dekker AJ, That L. Effect of delayed treatment with nerve growth factor on choline acetyltransferase activity in the cortex of rats with lesions of the nucleus basalis magnocellularis: dose requirements. Brain Res 1992; 584: 55-63.
    • (1992) Brain Res , vol.584 , pp. 55-63
    • Dekker, A.J.1    That, L.2
  • 10
    • 0028353076 scopus 로고
    • Grafting of nerve growth factor-producing fibroblasts reduces behavioral deficits in rats with lesions of the nucleus basalis magnocellularis
    • Dekker AJ, Ray WJ, Tha LJ, Gage FH. Grafting of nerve growth factor-producing fibroblasts reduces behavioral deficits in rats with lesions of the nucleus basalis magnocellularis. Neuroscience 1994; 60: 299-309.
    • (1994) Neuroscience , vol.60 , pp. 299-309
    • Dekker, A.J.1    Ray, W.J.2    Tha, L.J.3    Gage, F.H.4
  • 11
    • 0031214428 scopus 로고    scopus 로고
    • Nerve growth factor attenuates cholinergic deficits following traumatic brain injury in rats
    • Dixon CE et al. Nerve growth factor attenuates cholinergic deficits following traumatic brain injury in rats. Exp Neurol 1997; 146: 479-490.
    • (1997) Exp Neurol , vol.146 , pp. 479-490
    • Dixon, C.E.1
  • 12
    • 0030974791 scopus 로고    scopus 로고
    • Delayed administration of basic fibroblast growth factor (bFGF) attenuates cognitive dysfunction following parasagittal fluid percussion brain injury in the rat
    • McDermott KL et al. Delayed administration of basic fibroblast growth factor (bFGF) attenuates cognitive dysfunction following parasagittal fluid percussion brain injury in the rat. J Neurotrauma 1997; 14: 191-198.
    • (1997) J Neurotrauma , vol.14 , pp. 191-198
    • McDermott, K.L.1
  • 13
    • 0030025668 scopus 로고    scopus 로고
    • Overexpression of Bcl-2 with herpes simplex virus vectors protects CNS neurons against neurological insults in vitro and in vivo
    • Lawrence MS et al. Overexpression of Bcl-2 with herpes simplex virus vectors protects CNS neurons against neurological insults in vitro and in vivo. J Neurosci 1996; 16: 486-496.
    • (1996) J Neurosci , vol.16 , pp. 486-496
    • Lawrence, M.S.1
  • 14
    • 0030772541 scopus 로고    scopus 로고
    • Herpes simplex viral vectors expressing Bcl-2 are neuroprotective when delivered after a stroke
    • Lawrence MS et al. Herpes simplex viral vectors expressing Bcl-2 are neuroprotective when delivered after a stroke. J Cereb Blood Flow Metab 1997; 17: 740-744.
    • (1997) J Cereb Blood Flow Metab , vol.17 , pp. 740-744
    • Lawrence, M.S.1
  • 15
    • 0006999810 scopus 로고    scopus 로고
    • Adenovirus-mediated gene delivery into neuronal precursors of the adult mouse brain
    • Yoon SO et al. Adenovirus-mediated gene delivery into neuronal precursors of the adult mouse brain. Proc Natl Acad Sci USA 1996; 93: 11974-11979.
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 11974-11979
    • Yoon, S.O.1
  • 16
    • 0029996147 scopus 로고    scopus 로고
    • In vivo gene delivery and stable transduction of nondividing cells by a lentiviral vector
    • Naldini L et al. In vivo gene delivery and stable transduction of nondividing cells by a lentiviral vector. Science 1996; 272: 263-267.
    • (1996) Science , vol.272 , pp. 263-267
    • Naldini, L.1
  • 17
    • 0029993858 scopus 로고    scopus 로고
    • Efficient transfer, integration, and sustained long-term expression of the transgene in adult rat brains injected with a lentiviral vector
    • Naldini L et al. Efficient transfer, integration, and sustained long-term expression of the transgene in adult rat brains injected with a lentiviral vector. Proc Natl Acad Sci USA 1996; 93: 11382-11388.
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 11382-11388
    • Naldini, L.1
  • 19
    • 0029915755 scopus 로고    scopus 로고
    • Direct intracerebral nerve growth factor gene transfer using a recombinant adenovirus: Effect on basal forebrain cholinergic neurons during aging
    • Castel-Barthe MN et al. Direct intracerebral nerve growth factor gene transfer using a recombinant adenovirus: effect on basal forebrain cholinergic neurons during aging. Neurobiol Dis 1996; 3: 76-86.
    • (1996) Neurobiol Dis , vol.3 , pp. 76-86
    • Castel-Barthe, M.N.1
  • 20
    • 0031019795 scopus 로고    scopus 로고
    • Dopaminergic neurons protected from degeneration by GDNF gene therapy
    • Choi-Lundberg DL et al. Dopaminergic neurons protected from degeneration by GDNF gene therapy. Science 1997; 275: 838-841.
    • (1997) Science , vol.275 , pp. 838-841
    • Choi-Lundberg, D.L.1
  • 21
    • 0030763998 scopus 로고    scopus 로고
    • Targeted transduction of CNS neurons with adenoviral vectors carrying neurotrophic factor genes confers neuroprotection that exceeds the transduced population
    • Baumgartner BJ, Shine HD. Targeted transduction of CNS neurons with adenoviral vectors carrying neurotrophic factor genes confers neuroprotection that exceeds the transduced population. J Neurosci 1997; 17: 6504-6511.
    • (1997) J Neurosci , vol.17 , pp. 6504-6511
    • Baumgartner, B.J.1    Shine, H.D.2
  • 22
    • 0030899994 scopus 로고    scopus 로고
    • Overexpression of interleukin-1 receptor antagonist in the mouse brain reduces ischemic brain injury
    • Yang GY, Zhao YJ, Davidson BL, Betz AL. Overexpression of interleukin-1 receptor antagonist in the mouse brain reduces ischemic brain injury. Brain Res 1997; 751: 181-188.
    • (1997) Brain Res , vol.751 , pp. 181-188
    • Yang, G.Y.1    Zhao, Y.J.2    Davidson, B.L.3    Betz, A.L.4
  • 23
    • 0023447252 scopus 로고
    • Lipofection: A highly efficient, lipid-mediated DNA-transfection procedure
    • Feigner PL et al. Lipofection: a highly efficient, lipid-mediated DNA-transfection procedure. Proc Natl Acad Sci USA 1987; 84: 7413-7417.
    • (1987) Proc Natl Acad Sci USA , vol.84 , pp. 7413-7417
    • Feigner, P.L.1
  • 24
    • 0030254351 scopus 로고    scopus 로고
    • Improvements in cationic liposomes for in vivo gene transfer
    • Feigner PL. Improvements in cationic liposomes for in vivo gene transfer. Hum Gene Ther 1996; 7: 1791-1793.
    • (1996) Hum Gene Ther , vol.7 , pp. 1791-1793
    • Feigner, P.L.1
  • 25
    • 0027517321 scopus 로고
    • Direct gene transfer with DNA liposome complexes in melanoma: Expression, biological activity, lack of toxicity in humans
    • Nabel GL. Direct gene transfer with DNA liposome complexes in melanoma: expression, biological activity, lack of toxicity in humans. Proc Natl Acad Sci USA 1993; 90: 11307-11311.
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 11307-11311
    • Nabel, G.L.1
  • 26
    • 0027313072 scopus 로고
    • Systemic gene expression after intravenous DNA delivery into adult mice
    • Zhu N, Liggitt D, Liu Y, Debs R. Systemic gene expression after intravenous DNA delivery into adult mice. Science 1993; 261: 209-211.
    • (1993) Science , vol.261 , pp. 209-211
    • Zhu, N.1    Liggitt, D.2    Liu, Y.3    Debs, R.4
  • 27
    • 0028282058 scopus 로고
    • Direct plasmid mediated transfection of adult murine brain cells in vivo using cationic liposomes
    • Roessler B, Davidson BL. Direct plasmid mediated transfection of adult murine brain cells in vivo using cationic liposomes. Neurosci Lett 1994; 167: 5-10.
    • (1994) Neurosci Lett , vol.167 , pp. 5-10
    • Roessler, B.1    Davidson, B.L.2
  • 28
    • 0029558004 scopus 로고
    • Cationic liposome-mediated gene transfer
    • Gao X, Huang L. Cationic liposome-mediated gene transfer. Gene Therapy 1995; 2: 710-722.
    • (1995) Gene Therapy , vol.2 , pp. 710-722
    • Gao, X.1    Huang, L.2
  • 29
    • 0030866645 scopus 로고    scopus 로고
    • In vivo gene transfer via intravenous administration of cationic lipid-protamine-DNA (LPD) complexes
    • Li S, Huang L. In vivo gene transfer via intravenous administration of cationic lipid-protamine-DNA (LPD) complexes. Gene Therapy 1997; 4: 891-900.
    • (1997) Gene Therapy , vol.4 , pp. 891-900
    • Li, S.1    Huang, L.2
  • 30
    • 0030956111 scopus 로고    scopus 로고
    • Gene therapy for central nervous system injury: The use of cationic liposomes: an invited review
    • Yang K, Clifton GL, Hayes RL. Gene therapy for central nervous system injury: the use of cationic liposomes: an invited review. J Neurotrauma 1997; 14: 281-297.
    • (1997) J Neurotrauma , vol.14 , pp. 281-297
    • Yang, K.1    Clifton, G.L.2    Hayes, R.L.3
  • 31
    • 0031766138 scopus 로고    scopus 로고
    • Novel pharmacological strategies in the treatment of experimental traumatic brain injury: 1998
    • McIntosh TK, Juhler M, Wieloch T. Novel pharmacological strategies in the treatment of experimental traumatic brain injury: 1998. J Neurotrauma 1998; 15: 731-769.
    • (1998) J Neurotrauma , vol.15 , pp. 731-769
    • McIntosh, T.K.1    Juhler, M.2    Wieloch, T.3
  • 32
    • 0029867953 scopus 로고    scopus 로고
    • Liposome-mediated NGF gene transfection increases ChAT activity in rat septo-hippocampal cell cultures
    • Le W et al. Liposome-mediated NGF gene transfection increases ChAT activity in rat septo-hippocampal cell cultures. NeuroReport 1996; 7: 710-712.
    • (1996) NeuroReport , vol.7 , pp. 710-712
    • Le, W.1
  • 33
    • 0030811950 scopus 로고    scopus 로고
    • DC-Chol liposome-mediated gene transfer in rat spinal cord
    • Yang K et al. DC-Chol liposome-mediated gene transfer in rat spinal cord. NeuroReport 1997; 8: 2355-2358.
    • (1997) NeuroReport , vol.8 , pp. 2355-2358
    • Yang, K.1
  • 34
    • 0028035103 scopus 로고
    • Optimizing liposome-mediated gene transfer in primary rat septo-hippocampal cell cultures
    • Yang K et al. Optimizing liposome-mediated gene transfer in primary rat septo-hippocampal cell cultures. Neurosci Lett 1994; 182: 287-290.
    • (1994) Neurosci Lett , vol.182 , pp. 287-290
    • Yang, K.1
  • 35
    • 0029095275 scopus 로고
    • Brief potassium depolarization decreases neurofilament proteins in CNS culture
    • Whitson JS et al. Brief potassium depolarization decreases neurofilament proteins in CNS culture. Brain Res 1995; 694: 213-222.
    • (1995) Brain Res , vol.694 , pp. 213-222
    • Whitson, J.S.1
  • 36
    • 0027525494 scopus 로고
    • Gene therapy for neurologic disease
    • Suhr ST, Gage FH. Gene therapy for neurologic disease. Arch Neurol 1993; 50: 1252-1268.
    • (1993) Arch Neurol , vol.50 , pp. 1252-1268
    • Suhr, S.T.1    Gage, F.H.2
  • 37
    • 0028910695 scopus 로고
    • Gene expression from recombinant viral vectors in the central nervous system after blood-brain barrier disruption
    • Doran SE et al. Gene expression from recombinant viral vectors in the central nervous system after blood-brain barrier disruption. Neurosurgery 1995; 36: 965-970.
    • (1995) Neurosurgery , vol.36 , pp. 965-970
    • Doran, S.E.1
  • 38
    • 0029915345 scopus 로고    scopus 로고
    • Cationic lipid-mediated delivery and expression of prepro-neuropeptide Y cDNA after intraventricular administration in rat: Feasibility and limitations
    • Thorsell A, Lomqvist AG, Heilig M. Cationic lipid-mediated delivery and expression of prepro-neuropeptide Y cDNA after intraventricular administration in rat: feasibility and limitations. Reg Pept 1996; 61: 205-211.
    • (1996) Reg Pept , vol.61 , pp. 205-211
    • Thorsell, A.1    Lomqvist, A.G.2    Heilig, M.3
  • 39
    • 0028913411 scopus 로고
    • Liposome-mediated CFTR gene transfer to the nasal epithelium of patients with cystic fibrosis
    • Caplen NJ et al. Liposome-mediated CFTR gene transfer to the nasal epithelium of patients with cystic fibrosis. Nature Med 1995; 1: 39-46.
    • (1995) Nature Med , vol.1 , pp. 39-46
    • Caplen, N.J.1
  • 40
    • 0030794696 scopus 로고    scopus 로고
    • Effect of co-lipids in enhancing cationic lipid-mediated gene transfer in vitro and in vivo
    • Fasbender A et al. Effect of co-lipids in enhancing cationic lipid-mediated gene transfer in vitro and in vivo. Gene Therapy 1997; 4: 716-725.
    • (1997) Gene Therapy , vol.4 , pp. 716-725
    • Fasbender, A.1
  • 41
    • 0029040008 scopus 로고
    • Rescue of injury-induced loss by BDNF gene transfection in primary septo-hippocampal cell cultures
    • Hayes RL et al. Rescue of injury-induced loss by BDNF gene transfection in primary septo-hippocampal cell cultures. Neurosci Lett 1995; 191: 121-125.
    • (1995) Neurosci Lett , vol.191 , pp. 121-125
    • Hayes, R.L.1
  • 42
    • 0030910003 scopus 로고    scopus 로고
    • The effects of nerve growth factor on spatial recent memory in aged rats persist after discontinuation of treatment
    • Frick KM, Price DL, Koliatsos VE, Markowska AL. The effects of nerve growth factor on spatial recent memory in aged rats persist after discontinuation of treatment. J Neurosci 1997; 17: 2543-2550.
    • (1997) J Neurosci , vol.17 , pp. 2543-2550
    • Frick, K.M.1    Price, D.L.2    Koliatsos, V.E.3    Markowska, A.L.4
  • 43
    • 0029867844 scopus 로고    scopus 로고
    • Ex vivo gene transfer of brain-derived neurotrophic factor to the intact rat forebrain: Neurotrophic effects on cholinergic neurons
    • Martinez-Serrano A, Hantzopoulos PA, Bjorklund A. Ex vivo gene transfer of brain-derived neurotrophic factor to the intact rat forebrain: neurotrophic effects on cholinergic neurons. Eur J Neurosci 1996; 8: 727-735.
    • (1996) Eur J Neurosci , vol.8 , pp. 727-735
    • Martinez-Serrano, A.1    Hantzopoulos, P.A.2    Bjorklund, A.3
  • 44
    • 0028786119 scopus 로고
    • Nerve growth factor administration attenuates cognitive but not neurobehavioral motor dysfunction or hippocampal cell loss following fluid-percussion brain injury in rats
    • Sinson G, Voddi M, McIntosh TK. Nerve growth factor administration attenuates cognitive but not neurobehavioral motor dysfunction or hippocampal cell loss following fluid-percussion brain injury in rats. J Neurochem 1995; 65: 2209-2216.
    • (1995) J Neurochem , vol.65 , pp. 2209-2216
    • Sinson, G.1    Voddi, M.2    McIntosh, T.K.3
  • 45
    • 0029865479 scopus 로고    scopus 로고
    • Combined fetal neural transplantation and nerve growth factor infusion: Effects on neurological outcome following fluid-percussion brain injury in the rat
    • Sinson G, Voddi M, McIntosh TK. Combined fetal neural transplantation and nerve growth factor infusion: effects on neurological outcome following fluid-percussion brain injury in the rat. J Neurosurg 1996; 84: 665-662.
    • (1996) J Neurosurg , vol.84 , pp. 665-1662
    • Sinson, G.1    Voddi, M.2    McIntosh, T.K.3
  • 46
    • 0024332481 scopus 로고
    • Nerve growth factor receptor and choline acetyltransferase colocalization in neurons within the rat forebrain: Response to fimbria-fornix transection
    • Batchelor PE et al. Nerve growth factor receptor and choline acetyltransferase colocalization in neurons within the rat forebrain: response to fimbria-fornix transection. J Comp Neurol 1989; 284: 187-204.
    • (1989) J Comp Neurol , vol.284 , pp. 187-204
    • Batchelor, P.E.1
  • 47
    • 0028343937 scopus 로고
    • Polymer-encapsulated cells genetically modified to secrete human nerve growth factor promote the survival of axotomized septal cholinergic neurons
    • Winn SR et al. Polymer-encapsulated cells genetically modified to secrete human nerve growth factor promote the survival of axotomized septal cholinergic neurons. Proc Natl Acad Sci USA 1994; 91: 2324-2328.
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 2324-2328
    • Winn, S.R.1
  • 48
    • 0025168085 scopus 로고
    • Brain derived neurotrophic factor increases survival and differentiated functions of rat sepral cholinergic neurons
    • Alderson RF, Alterman AL, Barde YA, Lindsay RM. Brain derived neurotrophic factor increases survival and differentiated functions of rat sepral cholinergic neurons. Neuron 1990; 5: 297-306.
    • (1990) Neuron , vol.5 , pp. 297-306
    • Alderson, R.F.1    Alterman, A.L.2    Barde, Y.A.3    Lindsay, R.M.4
  • 49
    • 0028348091 scopus 로고
    • Nerve growth factor increases extracellular acetylcholine levels in the parietal cortex and hippocampus of aged rats and restores object recognition
    • Scali C et al. Nerve growth factor increases extracellular acetylcholine levels in the parietal cortex and hippocampus of aged rats and restores object recognition. Neurosci Lett 1994; 170: 117-120.
    • (1994) Neurosci Lett , vol.170 , pp. 117-120
    • Scali, C.1
  • 50
    • 0029013323 scopus 로고
    • Bridging grafts and transient nerve growth factor infusions promote long-term central nervous system neuronal rescue and partial functional recovery
    • Tuszynski MH, Gage FH. Bridging grafts and transient nerve growth factor infusions promote long-term central nervous system neuronal rescue and partial functional recovery. Proc Natl Acad Sci USA 1995; 92: 4621-4625.
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 4621-4625
    • Tuszynski, M.H.1    Gage, F.H.2
  • 51
    • 0030002982 scopus 로고    scopus 로고
    • Gene therapy in the adult primate brain: Intraparenchymal grafts of cells genetically modified to produce nerve growth factor prevent cholinergic neuronal degeneration
    • Tuszynsk MH, Roberts J, Senut M-C, Gage FH. Gene therapy in the adult primate brain: intraparenchymal grafts of cells genetically modified to produce nerve growth factor prevent cholinergic neuronal degeneration. Gene Therapy 1996; 3: 305-314.
    • (1996) Gene Therapy , vol.3 , pp. 305-314
    • Tuszynsk, M.H.1    Roberts, J.2    Senut, M.-C.3    Gage, F.H.4
  • 52
    • 0029957824 scopus 로고    scopus 로고
    • Effects of intraventricular transplantation of NGF-secreting cells on cholinergic basal forebrain neurons after partial immunolesion
    • Roner S et al. Effects of intraventricular transplantation of NGF-secreting cells on cholinergic basal forebrain neurons after partial immunolesion. J Neurosci Res 1996; 45: 40-56.
    • (1996) J Neurosci Res , vol.45 , pp. 40-56
    • Roner, S.1
  • 53
    • 0032078127 scopus 로고    scopus 로고
    • Significant behavioral recovery in Parkinson's disease model by direct intracerebral gene transfer using continuous injection of a plasmid DNA-liposome complex
    • Imaoka T, Date I, Ohmoto T, Nagatsu T. Significant behavioral recovery in Parkinson's disease model by direct intracerebral gene transfer using continuous injection of a plasmid DNA-liposome complex. Hum Gene Ther 1998; 9: 1093-1102.
    • (1998) Hum Gene Ther , vol.9 , pp. 1093-1102
    • Imaoka, T.1    Date, I.2    Ohmoto, T.3    Nagatsu, T.4
  • 54
    • 0026774150 scopus 로고
    • Suppression of audiogenic epileptic seizures by intracerebral injection of a CCK gene vector
    • Zhang LX, Wu M, Han JS. Suppression of audiogenic epileptic seizures by intracerebral injection of a CCK gene vector. NeuroReport 1992; 3: 700-702.
    • (1992) NeuroReport , vol.3 , pp. 700-702
    • Zhang, L.X.1    Wu, M.2    Han, J.S.3
  • 55
    • 0031035730 scopus 로고    scopus 로고
    • Lipofectin-facilitated transfer of cholecystokinin gene corrects behavioral abnormalities of rats with audiogenic seizures
    • Zhang LX et al. Lipofectin-facilitated transfer of cholecystokinin gene corrects behavioral abnormalities of rats with audiogenic seizures. Neuroscience 1997; 77: 15-22.
    • (1997) Neuroscience , vol.77 , pp. 15-22
    • Zhang, L.X.1
  • 56
    • 0030608484 scopus 로고    scopus 로고
    • Liposome-mediated NGF gene transfection increases phosphorylated neurofilament proteins
    • Yang K et al. Liposome-mediated NGF gene transfection increases phosphorylated neurofilament proteins. Mol Brain Res 1996; 43: 13-20.
    • (1996) Mol Brain Res , vol.43 , pp. 13-20
    • Yang, K.1
  • 57
    • 0032522480 scopus 로고    scopus 로고
    • Activation of phosphatidylinositol 3 kinase by BDNF gene transfection in septo-hippocampal cultures
    • Qiu YH et al. Activation of phosphatidylinositol 3 kinase by BDNF gene transfection in septo-hippocampal cultures. J Neurosci Res 1998; 52: 192-200.
    • (1998) J Neurosci Res , vol.52 , pp. 192-200
    • Qiu, Y.H.1
  • 58
    • 0017350927 scopus 로고
    • Rat hippocampal neurons in dispersed cell culture
    • Banker GA, Cowan WM. Rat hippocampal neurons in dispersed cell culture. Brain Res 1977; 126: 397-425.
    • (1977) Brain Res , vol.126 , pp. 397-425
    • Banker, G.A.1    Cowan, W.M.2
  • 59
    • 0024340539 scopus 로고
    • Survival and growth of hippocampal neurons in defined medium at low density: Advantages of a sandwich culture technique or low oxygen
    • Brewer GJ, Cotman CW. Survival and growth of hippocampal neurons in defined medium at low density: advantages of a sandwich culture technique or low oxygen. Brain Res 1989; 494: 65-74.
    • (1989) Brain Res , vol.494 , pp. 65-74
    • Brewer, G.J.1    Cotman, C.W.2
  • 60
    • 0028046716 scopus 로고
    • Sustained expression of functional nerve growth factor in primary septohippocampal cell cultures by liposome-mediated gene transfer
    • Yang K et al. Sustained expression of functional nerve growth factor in primary septohippocampal cell cultures by liposome-mediated gene transfer. Neurosci Lett 1994; 182: 291-294.
    • (1994) Neurosci Lett , vol.182 , pp. 291-294
    • Yang, K.1
  • 61
    • 1842382333 scopus 로고
    • In vitro studies of liposome-mediated gene transfection
    • Perez-Polo JR (ed). Academic Press: San Diego
    • Yang K et al. In vitro studies of liposome-mediated gene transfection. In: Perez-Polo JR (ed). Paradigms in Neural Injury. Academic Press: San Diego, 1995, pp 290-297.
    • (1995) Paradigms in Neural Injury , pp. 290-297
    • Yang, K.1
  • 62
    • 0026062640 scopus 로고
    • A controlled cortical impact model of traumatic brain injury in the rat
    • Dixon CE et al. A controlled cortical impact model of traumatic brain injury in the rat. J Neurosci Meth 1991; 39: 253-262.
    • (1991) J Neurosci Meth , vol.39 , pp. 253-262
    • Dixon, C.E.1
  • 63
    • 0029916808 scopus 로고    scopus 로고
    • BDNF cDNA following liposome-mediated gene transfer in intact and traumatically injured rat brain
    • Iwamoto Y et al. BDNF cDNA following liposome-mediated gene transfer in intact and traumatically injured rat brain. NeuroReport 1996; 7: 609-612.
    • (1996) NeuroReport , vol.7 , pp. 609-612
    • Iwamoto, Y.1
  • 64
    • 0345704610 scopus 로고
    • Establishment of a noradrenergic clonal line of rat adrenal pheochromocytoma cells which respond to NGF
    • Greene LA, Tischler AS. Establishment of a noradrenergic clonal line of rat adrenal pheochromocytoma cells which respond to NGF. Proc Natl Acad Sci USA 1976; 73: 2424-2428.
    • (1976) Proc Natl Acad Sci USA , vol.73 , pp. 2424-2428
    • Greene, L.A.1    Tischler, A.S.2


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