Synthesis and 11C-labelling of two selective high affinity nicotinic cholinergic agonists for evaluation as radioligands for PET studies

Journal of Labelled Compounds and Radiopharmaceuticals

Volumn 38, Issue 12, 1996, Pages 1099-1112

  Dolle, Frédéric ^a   Dolci, Lilian ^a   Valette, Héric ^a   Bottlaender, Michel ^a   Fournier, Denis ^a   Fuseau, Chantai ^a   Vaufrey, Françoise ^a   Crouzel, Christian ^a  

^a SERVICE HOSPITALIER FRÉDÉRIC JOLIOT   (France)

Author keywords

ABT 418; Brain nicotinic receptors; Carbon 11; N methylcytisine; Positron emission tomography

Indexed keywords

ALKYLATION; BRAIN; BRAIN MAPPING; CARBON; METHYLATION; POSITRONS;

ABT-418; BRAIN NICOTINIC RECEPTOR; CARBON-11; CHOLINERGIC AGONISTS; CYTISINES; HIGH AFFINITY; IN-VIVO; LABELINGS; N-METHYLCYTISINE; NICOTINIC RECEPTOR;

POSITRON EMISSION TOMOGRAPHY;

3 METHYL 5 (1 METHYL 2 PYRROLIDINYL)ISOXAZOLE; CARBON 11; CHOLINERGIC RECEPTOR STIMULATING AGENT; NICOTINE; NICOTINIC RECEPTOR;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BABOON; BRAIN CORTEX; CHIRALITY; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG DISTRIBUTION; DRUG RECEPTOR BINDING; DRUG SYNTHESIS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; INTRAVENOUS DRUG ADMINISTRATION; ISOTOPE LABELING; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; POSITRON EMISSION TOMOGRAPHY; RADIOCHEMISTRY;

ANIMALIA; PAPIO HAMADRYAS;

EID: 0029851012     PISSN: 03624803     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1099-1344(199612)38:12<1099::AID-JLCR934>3.0.CO;2-G     Document Type: Article

References (27)

1. Giacobini E. - J. Neurosci. Res. 27: 548 (1990)
2. Whitehouse P.J., Martino A.M., Antuono P.G., Lowenstein P.R., Coyle P.R., Price J.T. and Kellar K.J. - Brain Res. 371: 146 (1986)
3. Rinne J.O., Myllykyä T., Lönnberg P. and Majaräki P. - Brain Res. 547: 167 (1991)
4. Mazière M., Berger G., Masse R., Plummer R. and Comar D. - The "in vivo" distribution of carbon-11 labelled (-)-nicotine in animals, a method suitable for use in man. Electrophysiological effects of nicotine, Remond A. and Izard C. Eds, Elsevier, North Holland Biomedical Press, Amsterdam, pp31-47, 1979
5. Nordberg A., Hartvig P., Lundquist H., Antoni G., Ulin J. and Langström B. - J. Neural. Transm., P-D Sect 1: 195(1989)
6. Halldin C., Nagren K., Swahn C., Langström B. and Nyback H. - Nucl. Med. Biol. 19: 871 (1992)
7. Nordberg A., Hartvig P., Lilja A., Vittanen M., Amberla K., Ulin J., Winblad B. and Langström B. - J. Neural. Transm., P-D Sect 2: 215 (1990)
8. Nybäck H., Halldin C., Ahlin A., Curvall M. and Eriksson L. - Psychopharmacol. 115: 31 (1994)
9. Broussolle E.P., Wong D.F., Fanelli R.J. and London E.D. - Life Sci. 44: 1123 (1989)
10. Arneric S.P., Anderson D.J., Bannen A.W., Briggs C.A., Buccafusco J.J., Brioni J.D., Decker M.W., Donnelly-Roberts D., Gopalakrishnan M., Holladay M.W., Kyncl J., Marsh K.C., Pauly J., Radek R.J., Rodrigues A.D. and Sullivan J.P. - CNS Drug reviews, in press
11. Garvey D.S, Wasinak J.T., Decker M.W., Brioni J.D., Buckley M.J., Sullivan J.P., Carrera G.M., Holladay M.W., Arneric S.P. and Williams M. - J. Med. Chem. 37: 1055 (1994)
12. Anderson D.J., Williams M., Pauly J.R., Raskiewicz J.L., Campbell J.E., Rotert G., Surber B., Thomas S.B., Wasicak J., Arneric S.P. and Sullivan J.P. - J. Pharmacol. Exp. Ther. 273: 1434(1995)
13. Decker M.W., Brioni J.D., Bannon A.W. and Arneric S.P. - Life Sci. 56: 545 (1995)
14. Schmeller T., Sauerwein M., Sporer F., Wink M. and Müller W. - J. Nat. Prod. 57: 1316 (1994)
15. Barlow R.B. and McLeod L.J. - Br. J. Pharmac. 35: 161 (1969)
16. Parikh J.R. and von E. Doering W. - J. Am. Chem. Soc. 89: 5505 (1967)
17. Hamada Y. and Shioiri T. - Chem. Pharm. Bull. 30(5): 1921 (1982)
18. Corey E.J. and Fuchs P.L. - Tetrahedron Lett. 36: 3769 (1972)
19. Chung J.Y.L. and Wasicak J.T. - Tetrahedron Lett. 31(28): 3957 (1990)
20. Grundmann C. and Grünanger P. - The nitrile oxydes, Springer-Verlag, 1971
21. MukaiyamaT. and Hoshino T. - J. Am. Chem. Soc. 82: 5339 (1960)
22. Eschweiler W. - Chem. Ber. 38: 880 (1905)
23. Clarke H.T. - J. Am. Chem. Soc. 55: 4571 (1933)
24. Crouzel C., Langstrom B., Pike V.W. and Coenen H.H. - Appl. Radiat. Isot. 38: 601 (1987)
25. Flesher J.E., Scheffel U., London E.D. and Frost J.J. - Life Sci. 54: 1883 (1994)
26. Pettit G.R., Singh S.B., Herald S.L., Lloyd-Williams P., Kantoci D., Burkett D.D., Barkoczy J., Hogan F. and Wardlaw T.R. - J; Org. Chem. 59: 6287 (1994)
27. Wittenberger S.J. - J; Org. Chem. 61: 356 (1996)