메뉴 건너뛰기




Volumn 54, Issue 6, 1999, Pages 554-557

Immunomodulation by interference with co-stimulatory molecules: Therapeutic perspectives in asthma

Author keywords

[No Author keywords available]

Indexed keywords

B7 ANTIGEN; CD86 ANTIGEN; GAMMA INTERFERON; INTERCELLULAR ADHESION MOLECULE 1; INTERLEUKIN 4; INTERLEUKIN 5; LYMPHOCYTE FUNCTION ASSOCIATED ANTIGEN 3; RECOMBINANT PROTEIN; T LYMPHOCYTE RECEPTOR;

EID: 0033013829     PISSN: 00406376     EISSN: None     Source Type: Journal    
DOI: 10.1136/thx.54.6.554     Document Type: Short Survey
Times cited : (10)

References (49)
  • 1
    • 0001091115 scopus 로고    scopus 로고
    • Accessory cell-lymphocyte interactions
    • Crystal RG, Weibel ER, Barnes PJ, eds. Philadelphia: Lippincott-Raven
    • 1 Hance AJ. Accessory cell-lymphocyte interactions. In: Crystal RG, Weibel ER, Barnes PJ, eds. The Lung: Scientific Foundations. 2nd ed. Philadelphia: Lippincott-Raven, 1997: 821-39.
    • (1997) The Lung: Scientific Foundations. 2nd Ed. , pp. 821-839
    • Hance, A.J.1
  • 2
    • 0025937503 scopus 로고
    • Immunologic system in the respiratory tract
    • 2 Reynolds HY. Immunologic system in the respiratory tract. Physiol Rev 1991;71:1117-33.
    • (1991) Physiol Rev , vol.71 , pp. 1117-1133
    • Reynolds, H.Y.1
  • 3
    • 0028901076 scopus 로고
    • Human alveolar macrophages present antigen ineffectively due to defective expression of B7 costimulatory cell surface molecules
    • 3 Chelen CJ, Fang Y, Freeman GJ, et al. Human alveolar macrophages present antigen ineffectively due to defective expression of B7 costimulatory cell surface molecules. J Clin Invest. 1995;95:1415-21.
    • (1995) J Clin Invest. , vol.95 , pp. 1415-1421
    • Chelen, C.J.1    Fang, Y.2    Freeman, G.J.3
  • 4
    • 0031181270 scopus 로고    scopus 로고
    • Alveolar macrophages in sarcoidosis coexpress high levels of CD86 (B7.2), CD40, and CD30L
    • 4 Nicod LP, Isler P. Alveolar macrophages in sarcoidosis coexpress high levels of CD86 (B7.2), CD40, and CD30L. Am J Respir Cell Mol Biol 1997;17:91-6.
    • (1997) Am J Respir Cell Mol Biol , vol.17 , pp. 91-96
    • Nicod, L.P.1    Isler, P.2
  • 5
    • 0025762391 scopus 로고
    • Studies on the density, distribution, and surface phenotype of intraepithelial class II major histocompatibility complex antigen (Ia)-bearing dendritic cells (DC) in the conducting airways
    • 5 Schon-Hegrad MA, Oliver J, McMenamin PG, et al. Studies on the density, distribution, and surface phenotype of intraepithelial class II major histocompatibility complex antigen (Ia)-bearing dendritic cells (DC) in the conducting airways. J Exp Med 1991;173:1345-56.
    • (1991) J Exp Med , vol.173 , pp. 1345-1356
    • Schon-Hegrad, M.A.1    Oliver, J.2    McMenamin, P.G.3
  • 6
    • 0028953093 scopus 로고
    • The antigen-presenting activities of Ia+ dendritic cells shift dynamically from lung to lymph node after an airway challenge with soluble antigen
    • 6 Xia W, Pinto CE, Kradin RL. The antigen-presenting activities of Ia+ dendritic cells shift dynamically from lung to lymph node after an airway challenge with soluble antigen. J Exp Med 1995;181:1275-83.
    • (1995) J Exp Med , vol.181 , pp. 1275-1283
    • Xia, W.1    Pinto, C.E.2    Kradin, R.L.3
  • 7
    • 0031792075 scopus 로고    scopus 로고
    • Selective differences in the expression of homing receptors of helper lymphocyte subsets
    • 7 Burastero SE, Rossi GA, Crimi E. Selective differences in the expression of homing receptors of helper lymphocyte subsets. Clin Immunol Immunopathol 1998;89:110-6.
    • (1998) Clin Immunol Immunopathol , vol.89 , pp. 110-116
    • Burastero, S.E.1    Rossi, G.A.2    Crimi, E.3
  • 9
    • 0029032046 scopus 로고
    • Molecular mechanisms underlying functional T-cell unresponsiveness
    • 9 Mueller DL, Jenkins MK. Molecular mechanisms underlying functional T-cell unresponsiveness. Curr Opin Immunol 1995;7:375-81.
    • (1995) Curr Opin Immunol , vol.7 , pp. 375-381
    • Mueller, D.L.1    Jenkins, M.K.2
  • 10
    • 0026537347 scopus 로고
    • CD28-mediated signalling co-stimulates murine T cells and prevents induction of anergy in T-cell clones
    • 10 Harding FA, McArthur JG, Gross JA, et al. CD28-mediated signalling co-stimulates murine T cells and prevents induction of anergy in T-cell clones. Nature 1992;356:607-9.
    • (1992) Nature , vol.356 , pp. 607-609
    • Harding, F.A.1    McArthur, J.G.2    Gross, J.A.3
  • 11
    • 0024506159 scopus 로고
    • Regulation of lymphokine messenger RNA stability by a surface-mediated T cell activation pathway
    • 11 Lindstein T, June CH, Ledbetter JA, et al. Regulation of lymphokine messenger RNA stability by a surface-mediated T cell activation pathway. Science 1989;244:339-43.
    • (1989) Science , vol.244 , pp. 339-343
    • Lindstein, T.1    June, C.H.2    Ledbetter, J.A.3
  • 12
    • 0027282960 scopus 로고
    • Characterization of CTLA-4 structure and expression on human T cells
    • 12 Lindsten T, Lee KP, Harris ES, et al. Characterization of CTLA-4 structure and expression on human T cells. J Immunol 1993;151:3489-99.
    • (1993) J Immunol , vol.151 , pp. 3489-3499
    • Lindsten, T.1    Lee, K.P.2    Harris, E.S.3
  • 13
    • 0028867420 scopus 로고
    • Loss of CTLA-4 leads to massive lymphoproliferation and fatal multiorgan tissue destruction, revealing a critical negative regulatory role of CTLA-4
    • 13 Tivol EA, Borriello F, Schweitzer AN, et al. Loss of CTLA-4 leads to massive lymphoproliferation and fatal multiorgan tissue destruction, revealing a critical negative regulatory role of CTLA-4. Immunity 1995;3:541-7.
    • (1995) Immunity , vol.3 , pp. 541-547
    • Tivol, E.A.1    Borriello, F.2    Schweitzer, A.N.3
  • 14
    • 0030002225 scopus 로고    scopus 로고
    • IFN-gamma-induced MHC class II gene expression is suppressed in endothelial cells by dextran sulfate
    • 14 Lian RH, Kotwal GJ, Wellhausen SR, et al. IFN-gamma-induced MHC class II gene expression is suppressed in endothelial cells by dextran sulfate. J Immunol 1996;157: 864-73.
    • (1996) J Immunol , vol.157 , pp. 864-873
    • Lian, R.H.1    Kotwal, G.J.2    Wellhausen, S.R.3
  • 15
    • 0028981056 scopus 로고
    • Interferon-gamma upregulates interleukin-3 (IL-3) receptor expression in human endothelial cells and synergizes with IL-3 in stimulating major histocompatibility complex class II expression and cytokine production
    • 15 Korpelainen EI, Gamble JR, Smith WB, et al. Interferon-gamma upregulates interleukin-3 (IL-3) receptor expression in human endothelial cells and synergizes with IL-3 in stimulating major histocompatibility complex class II expression and cytokine production. Blood 1995;86:176-82.
    • (1995) Blood , vol.86 , pp. 176-182
    • Korpelainen, E.I.1    Gamble, J.R.2    Smith, W.B.3
  • 16
    • 0028279251 scopus 로고
    • Characterization of a cis-acting regulatory clement which silences expression of the class II-A beta gene in epithelium
    • 16 Albert SE, Strutz, F, Shelton K, et al. Characterization of a cis-acting regulatory clement which silences expression of the class II-A beta gene in epithelium. J Exp Med 1994;180:233-40.
    • (1994) J Exp Med , vol.180 , pp. 233-240
    • Albert, S.E.1    Strutz, F.2    Shelton, K.3
  • 17
    • 0027318690 scopus 로고
    • Differential control of major histocompatibility complex class II I-Ek alpha protein expression in the epithelium and in subsets of lamina propria antigen-presenting cells of the gut
    • 17 Bland PW, Whiting CV. Differential control of major histocompatibility complex class II I-Ek alpha protein expression in the epithelium and in subsets of lamina propria antigen-presenting cells of the gut. Immunology 1993;79: 107-11.
    • (1993) Immunology , vol.79 , pp. 107-111
    • Bland, P.W.1    Whiting, C.V.2
  • 18
    • 0028902423 scopus 로고
    • Human vascular endothelial cells process and present autoantigen to human T cell lines
    • 18 Savage CO, Brooks CJ, Harcourt GC, et al. Human vascular endothelial cells process and present autoantigen to human T cell lines. Int Immunol 1995;7:471-9.
    • (1995) Int Immunol , vol.7 , pp. 471-479
    • Savage, C.O.1    Brooks, C.J.2    Harcourt, G.C.3
  • 19
    • 0029103046 scopus 로고
    • CD86 (B70/B7-2) on endothelial cells co-stimulates allogeneic CD4+ T cells
    • 19 Seino K, Azuma M, Bashuda H, et al. CD86 (B70/B7-2) on endothelial cells co-stimulates allogeneic CD4+ T cells. Int Immunol 1995;7:1331-7.
    • (1995) Int Immunol , vol.7 , pp. 1331-1337
    • Seino, K.1    Azuma, M.2    Bashuda, H.3
  • 20
    • 0031204681 scopus 로고    scopus 로고
    • Differential regulation of human, antigen-specific Th1 and Th2 responses by the B-7 homologues, CD80s and CD86
    • 20 Bashian GG, Braun CM, Huang SK, et al. Differential regulation of human, antigen-specific Th1 and Th2 responses by the B-7 homologues, CD80s and CD86. Am J Respir Cell Mol Biol 1997;17:235-42.
    • (1997) Am J Respir Cell Mol Biol , vol.17 , pp. 235-242
    • Bashian, G.G.1    Braun, C.M.2    Huang, S.K.3
  • 21
    • 0030051239 scopus 로고    scopus 로고
    • Differential requirements for co-stimulatory signals from B7 family members by resting versus recently activated memory T cells towards soluble recall antigens
    • 21 Yi-qun Z, Joost van Neerven RJ, Kasran A, et al. Differential requirements for co-stimulatory signals from B7 family members by resting versus recently activated memory T cells towards soluble recall antigens. Int Immunol 1996;8: 37-44.
    • (1996) Int Immunol , vol.8 , pp. 37-44
    • Yi-qun, Z.1    Joost Van Neerven, R.J.2    Kasran, A.3
  • 22
    • 0027930707 scopus 로고
    • The role of CD40 in the regulation of humoral and cell-mediated immunity
    • 22 Durie FH, Foy TM, Masters SR, et al. The role of CD40 in the regulation of humoral and cell-mediated immunity, Immunol Today 1994;15:406-11.
    • (1994) Immunol Today , vol.15 , pp. 406-411
    • Durie, F.H.1    Foy, T.M.2    Masters, S.R.3
  • 23
    • 0031463831 scopus 로고    scopus 로고
    • CD40 and CD40 ligand (CD154) are coexpressed on microvessels in vivo in human cardiac allograft rejection
    • 23 Reul RM, Fang JC, Denton MD, et al. CD40 and CD40 ligand (CD154) are coexpressed on microvessels in vivo in human cardiac allograft rejection. Transplantation 1997;64: 1765-74.
    • (1997) Transplantation , vol.64 , pp. 1765-1774
    • Reul, R.M.1    Fang, J.C.2    Denton, M.D.3
  • 24
    • 0030474264 scopus 로고    scopus 로고
    • Costimulatory function and expression of CD40 ligand, CD80, and CD86 in vascularized murine cardiac allograft rejection
    • 24 Hancock WW, Sayegh MH, Zheng XG, et al. Costimulatory function and expression of CD40 ligand, CD80, and CD86 in vascularized murine cardiac allograft rejection. Proc Natl Acad Sci USA 1996;93:13967-72.
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 13967-13972
    • Hancock, W.W.1    Sayegh, M.H.2    Zheng, X.G.3
  • 25
    • 0027499535 scopus 로고
    • Activated T cells induce expression of B7/KB1 on normal or leukemic B cells through a CD40-dependent signal
    • 25 Ranheim EA, Kipps TJ. Activated T cells induce expression of B7/KB1 on normal or leukemic B cells through a CD40-dependent signal. J Exp Med 1993;177:925-35.
    • (1993) J Exp Med , vol.177 , pp. 925-935
    • Ranheim, E.A.1    Kipps, T.J.2
  • 26
    • 0029787322 scopus 로고    scopus 로고
    • Identification of a costimulatory molecule rapidly induced by CD40L as CD44H
    • 26 Guo Y, Wu Y, Shinde S, et al. Identification of a costimulatory molecule rapidly induced by CD40L as CD44H. J Exp Med 1996;184:955-61.
    • (1996) J Exp Med , vol.184 , pp. 955-961
    • Guo, Y.1    Wu, Y.2    Shinde, S.3
  • 27
    • 0030936275 scopus 로고    scopus 로고
    • B7-1 and B7 2 have overlapping, critical roles in immunoglobulin class switching and germinal center formation
    • 27 Borriello F, Sethna MP, Boyd SD, et al. B7-1 and B7 2 have overlapping, critical roles in immunoglobulin class switching and germinal center formation. Immunity 1997;6:303-13.
    • (1997) Immunity , vol.6 , pp. 303-313
    • Borriello, F.1    Sethna, M.P.2    Boyd, S.D.3
  • 28
    • 0031569258 scopus 로고    scopus 로고
    • Role of costimulators in T cell differentiation: Studies using antigen-presenting cells lacking expression of CD80 or CD86
    • 28 Schweitzer AN, Borriello F, Wong RC, et al. Role of costimulators in T cell differentiation: studies using antigen-presenting cells lacking expression of CD80 or CD86. J Immunol 1997;158:2713-22.
    • (1997) J Immunol , vol.158 , pp. 2713-2722
    • Schweitzer, A.N.1    Borriello, F.2    Wong, R.C.3
  • 29
    • 0032530746 scopus 로고    scopus 로고
    • Studies using antigen-presenting cells lacking expression of both B7-1 (CD80) and B7-2 (CD86) show distinct requirements for B7 molecules during priming versus restimulation of Th2 but not Th1 cytokine production
    • 29 Schweitzer AN, Sharpe AH. Studies using antigen-presenting cells lacking expression of both B7-1 (CD80) and B7-2 (CD86) show distinct requirements for B7 molecules during priming versus restimulation of Th2 but not Th1 cytokine production. J Immunol 1998;161:2762-71.
    • (1998) J Immunol , vol.161 , pp. 2762-2771
    • Schweitzer, A.N.1    Sharpe, A.H.2
  • 30
    • 85038159801 scopus 로고    scopus 로고
    • CD80 expression on alveolar macrophages and presence of airway eosinophils in asthma and in rhinitis before and after allergen challenge
    • 30 Burastero SE, Magnani Z, Confetti C, et al. CD80 expression on alveolar macrophages and presence of airway eosinophils in asthma and in rhinitis before and after allergen challenge. Eur Respir J 1998;12(Suppl 28):112s.
    • (1998) Eur Respir J , vol.12 , Issue.SUPPL. 28
    • Burastero, S.E.1    Magnani, Z.2    Confetti, C.3
  • 31
    • 85038162139 scopus 로고    scopus 로고
    • CD80 molecule expression by alveolar macrophages (AM) is enhanced in allergic asthma and it is involved in allergen presentation to allergen-specific T-cells
    • 31 Burastero SE, Magnani Z, Confetti C, et al. CD80 molecule expression by alveolar macrophages (AM) is enhanced in allergic asthma and it is involved in allergen presentation to allergen-specific T-cells. Eur Rapir J 1998;12(Suppl 28):159s.
    • (1998) Eur Rapir J , vol.12 , Issue.SUPPL. 28
    • Burastero, S.E.1    Magnani, Z.2    Confetti, C.3
  • 32
    • 0028875547 scopus 로고
    • Oligoclonality of lung T lymphocytes following exposure to allergen in asthma
    • 32 Burastero SE, Crimi E, Balbo A, et al. Oligoclonality of lung T lymphocytes following exposure to allergen in asthma. J Immunol 1995;155:5836-46.
    • (1995) J Immunol , vol.155 , pp. 5836-5846
    • Burastero, S.E.1    Crimi, E.2    Balbo, A.3
  • 33
    • 0030066360 scopus 로고    scopus 로고
    • The repertoire of T-lymphocytes recovered by bronchoalveolar lavage from healthy nonsmokers
    • 33 Burastero SE, Borgonovo B, Gaffi D, et al. The repertoire of T-lymphocytes recovered by bronchoalveolar lavage from healthy nonsmokers. Eur Respir J 1996;9:319-27.
    • (1996) Eur Respir J , vol.9 , pp. 319-327
    • Burastero, S.E.1    Borgonovo, B.2    Gaffi, D.3
  • 34
    • 0032403458 scopus 로고    scopus 로고
    • Costimulation through CD86 is involved in airway antigen-presenting cell and T cell responses to allergen in atopic asthmatics
    • 34 Larché M, Till SJ, Haselden BM, et al. Costimulation through CD86 is involved in airway antigen-presenting cell and T cell responses to allergen in atopic asthmatics. J Immunol 1998;161:6375-82.
    • (1998) J Immunol , vol.161 , pp. 6375-6382
    • Larché, M.1    Till, S.J.2    Haselden, B.M.3
  • 35
    • 0027200001 scopus 로고
    • Frequency of allergen-specific T lymphocytes in blood and bronchial response to allergen in asthma
    • 35 Burastero SE, Fenoglio D, Crimi E, et al. Frequency of allergen-specific T lymphocytes in blood and bronchial response to allergen in asthma. J Allergy Clin Immunol 1993;91:1075-81.
    • (1993) J Allergy Clin Immunol , vol.91 , pp. 1075-1081
    • Burastero, S.E.1    Fenoglio, D.2    Crimi, E.3
  • 36
    • 0030724665 scopus 로고    scopus 로고
    • Recruitment of circulating allergen-specific T lymphocytes to the lung on allergen challenge in asthma
    • 36 Borgonovo B, Casorati G, Frittoli E, et al. Recruitment of circulating allergen-specific T lymphocytes to the lung on allergen challenge in asthma. J Allergy Clin Immunol 1997; 100:669-78.
    • (1997) J Allergy Clin Immunol , vol.100 , pp. 669-678
    • Borgonovo, B.1    Casorati, G.2    Frittoli, E.3
  • 37
    • 0025830902 scopus 로고
    • CTLA-4 is a second receptor for the B cell activation antigen B7
    • 37 Linsley PS, Brady W, Urnes M, et al. CTLA-4 is a second receptor for the B cell activation antigen B7. J Exp Med 1991;174:561-9.
    • (1991) J Exp Med , vol.174 , pp. 561-569
    • Linsley, P.S.1    Brady, W.2    Urnes, M.3
  • 38
    • 0031228810 scopus 로고    scopus 로고
    • Murine CTLA4-IgG treatment inhibits airway cosinophilia and hyperresponsiveness and attenuates IgE upregulation in a murine model of allergic asthma
    • 38 Van Oosterhout AJ, Hofstra CL, Shields R, et al. Murine CTLA4-IgG treatment inhibits airway cosinophilia and hyperresponsiveness and attenuates IgE upregulation in a murine model of allergic asthma. Am J Rispir Cell Mol Biol 1997;17:386-92.
    • (1997) Am J Rispir Cell Mol Biol , vol.17 , pp. 386-392
    • Van Oosterhout, A.J.1    Hofstra, C.L.2    Shields, R.3
  • 39
    • 12644303215 scopus 로고    scopus 로고
    • Inhibition of T cell costimulation abrogates airway hyperresponsiveness in a murine model
    • 39 Krinzman SJ, De Sanctis GT, Cernadas M, et al. Inhibition of T cell costimulation abrogates airway hyperresponsiveness in a murine model. J Clin Invest 1996;98:2693-9.
    • (1996) J Clin Invest , vol.98 , pp. 2693-2699
    • Krinzman, S.J.1    De Sanctis, G.T.2    Cernadas, M.3
  • 41
    • 15844404353 scopus 로고    scopus 로고
    • Long-term acceptance of skin and cardiac allografts after blocking CD40 and CD28 pathways
    • 41 Larsen CP, Elwood ET, Alexander DZ, et al. Long-term acceptance of skin and cardiac allografts after blocking CD40 and CD28 pathways. Nature 1996;381:434-8.
    • (1996) Nature , vol.381 , pp. 434-438
    • Larsen, C.P.1    Elwood, E.T.2    Alexander, D.Z.3
  • 42
    • 12644262358 scopus 로고    scopus 로고
    • CTLA4-Ig and anti-CD40 ligand prevent renal allograft rejection in primates
    • 42 Kirk AD, Harlan DM, Armstrong NN, et al. CTLA4-Ig and anti-CD40 ligand prevent renal allograft rejection in primates. Proc Natl Acad Sci USA 1997;94:8789-94.
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 8789-8794
    • Kirk, A.D.1    Harlan, D.M.2    Armstrong, N.N.3
  • 43
    • 0029073090 scopus 로고
    • Distinct roles for the costimulatory ligands B7-1 and B7-2 in T helper cell differentiation?
    • 43 Thompson CB. Distinct roles for the costimulatory ligands B7-1 and B7-2 in T helper cell differentiation? Cell 1995;81:979-82.
    • (1995) Cell , vol.81 , pp. 979-982
    • Thompson, C.B.1
  • 44
    • 0028949152 scopus 로고
    • B7-1 and B7-2 costimulatory molecules activate differentially the Th1/h2 developmental pathways: Application to autoimmune disease therapy
    • 44 Kuchroo VK, Das MP, Brown JA, et al. B7-1 and B7-2 costimulatory molecules activate differentially the Th1/h2 developmental pathways: application to autoimmune disease therapy. Cell 1995;80:707-18.
    • (1995) Cell , vol.80 , pp. 707-718
    • Kuchroo, V.K.1    Das, M.P.2    Brown, J.A.3
  • 45
    • 0028900297 scopus 로고
    • Differential effects of anti-B7-1 and anti-B7-2 monoclonal antibody treatment on the development of diabetes in the nonobese diabetic mouse
    • 45 Lenschow DJ, Ho SC, Sattar H, et al. Differential effects of anti-B7-1 and anti-B7-2 monoclonal antibody treatment on the development of diabetes in the nonobese diabetic mouse. J Exp Med 1995;181:1145-55.
    • (1995) J Exp Med , vol.181 , pp. 1145-1155
    • Lenschow, D.J.1    Ho, S.C.2    Sattar, H.3
  • 46
    • 0031092655 scopus 로고    scopus 로고
    • B7-CD28/ CTLA-4 costimulatory pathways are required for the development of T helper cell 2-mediated allergic airway-responses to inhaled antigens
    • 46 Keane-Myers A, Gause WC, Linsley PS, et al. B7-CD28/ CTLA-4 costimulatory pathways are required for the development of T helper cell 2-mediated allergic airway-responses to inhaled antigens. J Immunol 1997;158:2042-9.
    • (1997) J Immunol , vol.158 , pp. 2042-2049
    • Keane-Myers, A.1    Gause, W.C.2    Linsley, P.S.3
  • 47
    • 0031036085 scopus 로고    scopus 로고
    • CD80 costimulation is essential for the induction of airway eosinophilia
    • 47 Harris N, Peach R, Naemura J, et al. CD80 costimulation is essential for the induction of airway eosinophilia. J Exp Med 1997;185:177-82.
    • (1997) J Exp Med , vol.185 , pp. 177-182
    • Harris, N.1    Peach, R.2    Naemura, J.3
  • 48
    • 0030922681 scopus 로고    scopus 로고
    • Costimulation through B7-2 (CD86) is required for the induction of a lung mucosal T helper cell 2 (TH2) immune response and altered airway responsiveness
    • 48 Tsuyuki S, Tsuyuki J, Einsle K, et al. Costimulation through B7-2 (CD86) is required for the induction of a lung mucosal T helper cell 2 (TH2) immune response and altered airway responsiveness. J Exp Med 1997;185:1671-9.
    • (1997) J Exp Med , vol.185 , pp. 1671-1679
    • Tsuyuki, S.1    Tsuyuki, J.2    Einsle, K.3
  • 49
    • 0030030181 scopus 로고    scopus 로고
    • Differential effects of CTLA-4 substitutions on the binding of human CD80 (B7-1) and CD86 (B7-2)
    • 49 Morton PA, Fu XT, Stewart JA, et al. Differential effects of CTLA-4 substitutions on the binding of human CD80 (B7-1) and CD86 (B7-2). J Immunol 1996;156:1047-54.
    • (1996) J Immunol , vol.156 , pp. 1047-1054
    • Morton, P.A.1    Fu, X.T.2    Stewart, J.A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.