Inhibition of T cell costimulation abrogates airway hyperresponsiveness in a murine model

Journal of Clinical Investigation

Volumn 98, Issue 12, 1996, Pages 2693-2699

  Krinzman, Stephen J ^a   De Sanctis, George T ^b   Cernadas, Manuela ^b   Mark, David ^b   Wang, Yungsheng ^b   Listman, James ^b   Kobzik, Lester ^b,c   Donovan, Carolyn ^b   Nassr, Kussay ^b   Katona, Ildy ^d   Christian, David C ^a   Perkins, David L ^b   Finn, Patricia W ^b,e  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b BRIGHAM AND WOMEN S HOSPITAL   (United States)

^c HARVARD MEDICAL SCHOOL   (United States)

^d Uniformed Services University of the Health Sciences   (United States)

^e BETH ISRAEL DEACONESS MEDICAL CENTER   (United States)

Author keywords

airway hyperresponsiveness; asthma; costimulation; murine; T cells

Indexed keywords

B7 ANTIGEN; CD28 ANTIGEN; CYTOTOXIC T LYMPHOCYTE ANTIGEN 4; IMMUNOGLOBULIN G ANTIBODY; METHACHOLINE; MONOCLONAL ANTIBODY;

ANIMAL CELL; ANIMAL MODEL; ANIMAL TISSUE; ANTIGEN EXPRESSION; ANTIGEN PRESENTING CELL; ARTICLE; ASTHMA; BRONCHUS HYPERREACTIVITY; CONTROLLED STUDY; INHALATIONAL DRUG ADMINISTRATION; INHIBITION KINETICS; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; RECEPTOR BINDING; RECEPTOR BLOCKING; T LYMPHOCYTE ACTIVATION;

EID: 12644303215     PISSN: 00219738     EISSN: None     Source Type: Journal    
DOI: 10.1172/JCI119093     Document Type: Article

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