The repertoire of T-lymphocytes recovered by bronchoalveolar lavage from healthy nonsmokers

European Respiratory Journal

Volumn 9, Issue 2, 1996, Pages 319-327

  Burastero, S E ^a   Borgonovo, B ^a   Gaffi, D ^a   Frittoli, E ^a   Wack, A ^a   Rossi, G A ^c   Crimi, E ^b  

^a SAN RAFFAELE HOSPITAL   (Italy)

^b UNIVERSITY OF GENOA   (Italy)

^c G GASLINI INSTITUTE   (Italy)

Author keywords

Bronchoalveolar lavage; Immune repertoire; T cell receptor; T lymphocytes

Indexed keywords

T LYMPHOCYTE RECEPTOR;

ADULT; ARTICLE; CONTROLLED STUDY; ENVIRONMENTAL EXPOSURE; FEMALE; HUMAN; HUMAN CELL; HUMAN EXPERIMENT; LUNG LAVAGE; LYMPHOCYTE CLONE; MALE; NORMAL HUMAN; PRIORITY JOURNAL; RESPIRATORY SYSTEM; T LYMPHOCYTE;

ADULT; BASE SEQUENCE; BRONCHOALVEOLAR LAVAGE; BRONCHOALVEOLAR LAVAGE FLUID; DNA; FEMALE; HUMANS; MALE; MIDDLE AGED; MOLECULAR SEQUENCE DATA; NUCLEIC ACID HETERODUPLEXES; OLIGONUCLEOTIDE PROBES; POLYMERASE CHAIN REACTION; RECEPTORS, ANTIGEN, T-CELL, ALPHA-BETA; REPETITIVE SEQUENCES, NUCLEIC ACID; T-LYMPHOCYTES;

EID: 0030066360     PISSN: 09031936     EISSN: None     Source Type: Journal    
DOI: 10.1183/09031936.96.09020319     Document Type: Article

References (25)

1. Saltini C, Member ME, Crystal RG. T-lymphocytes compartmentalized on the epithelial surface of the lower respiratory tract express the very late activation antigen complex, VLA-1. Clin Immunol Immunopathol 1988; 46: 221-233.
2. Muller-Quernheim J, Saltini C, Sondermeyer P, Crystal RG. Compartmentalized activation of IL-2 gene by lung T-lymphocytes in active pulmonary sarcoidosis. J Immunol 1986; 137: 3475-3483.
3. Saltini C, Kirbi M, Trapnell BC, Tamura N. Biased accumulation of T-lymphocytes with memory type CD45 leukocyte common antigen gene expression on the epithelial surface of the human lung. J Exp Med 1990; 171: 1123-1140.
4. Holt PG. Downregulation of the immune response in the lower respiratory tract: the role of alveolar macrophages. Clin Exp Immunol 1986; 62: 261-270.
5. Orme IM, Collinf FM Aerogenic vaccination of mice with Mycobacterium bovis BCG. Tubercle 1986; 67: 133-140.
6. Harmsen AG, Muggenbury BA, Sniper MB, Bice DE. The role of macrophages in particle translocation from lung to lymph nodes. Science 1985; 230: 1277.
7. Schon-Hegrad MA, Oliver J, McMenamin PG, Holt PG. Studies on the density, distribution and surface phenotype of intraepithelial class II MHC complex (Ia) antigen-bearing dendritic cells in the conducting airways. J Exp Med 1991; 173: 1345-1356.
8. Balbi N, Valle MT, Oddera S, et al. T-lymphocytes γδ+ with Vδ2+ antigen receptors are present in increased numbers in a fraction of patients with tuberculosis or sarcoidosis. Am Rev Respir Dis 1993; 148: 1685-1690.
9. Gerblich AA, Salik H, Schuyler MR. Dynamic T-cell changes in peripheral blood and bronchoalvelar lavage after antigenic provocation in asthmatics. Am Rev Respir Dis 1990; 143: 533-537.
10. Burastero SE, Fenoglio D, Crimi E, Brusasco V, Rossi GA. Frequency of allergen specific T-cells in blood and bronchial response to allergen challenge in asthma. J Allergy Clin Immunol 1993; 91: 1075-1081.
11. Binns RM, Licence ST, Pabst R. Homing of blood, splenic and lung emigrant lymphoblasts: comparison with the behaviour of lymphocytes from these sources. Intern Immunol 1992; 4: 1011-1019.
12. Jogersen JL, Reay PA, Enrich EW, Davis M. Molecular components of T-cell recognition. Ann Rev Immunol 1992; 10: 835-873.
13. Quanjer PH. Standardized lung function testing. Report of working party on standardization of lung function testing. European Coal and Steel Community (ECSC). Bull Eur Physiopathol Respir 1983; 19 (Suppl. 5): 1-94.
14. Rossi GA, Crimi E, Oddera S, Gianiorio P, Brusasco V. Late-phase asthmatic reaction to inhaled allergen is associated with early recruitment of eosinophils in the airways. Am Rev Respir Dis 1991; 144: 379-383.
15. Chomoczynski P, Sacchi N. Single step method of RNA isolation by acid guanidium thiocyanate-phenol-chloroform extraction. Anal Biochem 1987; 126: 156-161.
16. Genevee C, Diu A, Nierat J, et al. An experimentally validated panel of subfamily-specific oligonucleotide primers (Vα1-w29/Vβ1-w24) for the study of human T-cell receptor variable gene segment usage by polymerase chain reaction. Eur J Immunol 1992; 22: 1261-1269.
17. Choi Y, Kotzin B, Herron L, Callahan J, Marrack P, Kappler J. Interactions of Staphylococcus aureus toxin superantigens with human T- cells. Proc Natl Acad Sci USA 1989; 243: 217-227.
18. Dellabona P, Padovan E, Casorati G, Brockhause M, Lanzavecchia A. An invariant Vα24/JαQ/Vβ11 T-cell receptor is expressed in all individuals by clonally expanded CD4-8- T-cells. J Exp Med 1994; 180: 1171-1176.
19. Giachino C, Rocci MP, De Libero G, Oderda G, Ansaldi N, Migone N. An alternative approach to the assessment of γδ T-cell clonality in coeliac disease intestinal lesions through cDNA heteroduplex analysis of T-cell receptor V-J junctions. Hum Immunol 1994; 40: 303-311.
20. Frieke Kuper C, Koornstra PJ, Hameleers DMH, et al. The role of nasopharyngeal lymphoid tissue. Immunol Today 1992; 13: 119-122.
21. Pabst R. Is BALT a major component of the human lung immune system? Immunol Today 1992; 13: 119-122.
22. Gant V, Cluzel M, Shakoor Z, Jon Rees P, Lee TH, Hamblin AS. Alveolar macrophage accessory cell function in bronchial asthma. Am Rev Respir Dis 1992; 146: 900-904.
23. Burastero SE, Crimi E, Balbo A, et al. Oligoclonality of lung T-lymphocytes following allergen inhalation in asthma. J Immunol 1995; 155: (in the press).
24. Del Prete G, DeCarli M, D'Elios M, et al. Allergen exposure induces the activation of allergen specific T-cells in the airway mucosa of patients with allergic diseases. Eur J Immunol 1993; 23: 1445-1449.
25. Dohi M, Yamamoto K, Masuko K, et al. Accumulation of multiple T-cell clonotypes in lungs of healthy individuals and patients with pulmonary sarcoidosis. J Immunol 1994; 152: 1983-1988.