Dihydrofolate reductase and cell growth activity inhibition by the β-carboline-benzoquinolizidine plant alkaloid deoxytubulosine from Alangium lamarckii: Its potential as an antimicrobial and anticancer agent

Bioorganic and Medicinal Chemistry

Volumn 7, Issue 6, 1999, Pages 1105-1110

  Rao, Kothapalli Narasimha ^a   Venkatachalam, Sekharipuram Raman ^a  

^a BHABHA ATOMIC RESEARCH CENTRE   (India)

Author keywords

Alangium lamarckii; Cytotoxicity; Deoxytubulosine; Dihydrofolate reductase; Inhibition; Lactobacillus leichmannii

Indexed keywords

ALKALOID; ANTINEOPLASTIC AGENT; BETA CARBOLINE DERIVATIVE; DEOXYTUBULOSINE; DIHYDROFOLATE REDUCTASE; UNCLASSIFIED DRUG;

ANTIMICROBIAL ACTIVITY; ANTINEOPLASTIC ACTIVITY; ARTICLE; CELL GROWTH; CHEMICAL REACTION KINETICS; CONTROLLED STUDY; ENZYME INHIBITION; GROWTH INHIBITION; LACTOBACILLUS; MEDICINAL PLANT; NONHUMAN;

ALKALOIDS; ANGIOSPERMS; ANTI-BACTERIAL AGENTS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; BINDING, COMPETITIVE; FOLIC ACID ANTAGONISTS; GROWTH INHIBITORS; INDIA; LACTOBACILLUS; PLANTS, MEDICINAL; QUINOLIZINES; TETRAHYDROFOLATE DEHYDROGENASE; TUBERCIDIN;

ALANGIUM; ALANGIUM LAMARCKII; LACTOBACILLUS LEICHMANNII;

EID: 0033008251     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0968-0896(98)00262-4     Document Type: Article

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