β-carboline-benzoquinolizidine alkaloid deoxytubulosine inhibits thymidylate synthase activity in leukemic leukocytes from patients with chronic myeloblastic leukemia and acute lymphoblastic leukemia

Anti-Cancer Drugs

Volumn 9, Issue 8, 1998, Pages 727-732

  Narasimha Rao, K ^a   Bhattacharya, R K ^a   Venkatachalam, S R ^a  

^a BHABHA ATOMIC RESEARCH CENTRE   (India)

Author keywords

Acute lymphoblastic leukemia; Antitumor compound; Chronic myeloblastic leukemia; Deoxytubulosine; Inhibition; Thymidylate synthase

Indexed keywords

ALKALOID; BETA CARBOLINE DERIVATIVE; DEOXYTUBULOSINE; PLANT EXTRACT; THYMIDYLATE SYNTHASE; UNCLASSIFIED DRUG;

ACUTE LYMPHOBLASTIC LEUKEMIA; ANTINEOPLASTIC ACTIVITY; ARTICLE; CHEMICAL STRUCTURE; CHRONIC MYELOID LEUKEMIA; CONTROLLED STUDY; DNA SYNTHESIS; ENZYME INHIBITION; HUMAN; HUMAN CELL; LEUKEMIA CELL; MEDICINAL PLANT; PRECURSOR; PRIORITY JOURNAL;

ADOLESCENT; ADULT; ANTINEOPLASTIC AGENTS; CHILD; CHILD, PRESCHOOL; FEMALE; HUMANS; LEUKEMIA, LYMPHOCYTIC, ACUTE; LEUKEMIA, MYELOID, CHRONIC; LEUKOCYTE COUNT; LEUKOCYTES; MALE; MIDDLE AGED; QUINOLIZINES; THYMIDYLATE SYNTHASE; TUBERCIDIN;

EID: 0039731920     PISSN: 09594973     EISSN: None     Source Type: Journal    
DOI: 10.1097/00001813-199809000-00008     Document Type: Article

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