Action of curcumin on the cytochrome P450-system catalyzing the activation of aflatoxin B1

Chemico-Biological Interactions

Volumn 100, Issue 1, 1996, Pages 41-51

  Firozi, P F ^a   Aboobaker, V S ^a   Bhattacharya, R K ^a  

^a BHABHA ATOMIC RESEARCH CENTRE   (India)

Author keywords

Aflatoxin B1; Curcumin; Cytochrome P450; DNA adduct; Monooxygenase

Indexed keywords

AFLATOXIN B1; CURCUMIN; CYTOCHROME P450; CYTOCHROME P450 REDUCTASE; PROTECTIVE AGENT; UNSPECIFIC MONOOXYGENASE;

ANIMAL TISSUE; ARTICLE; CARCINOGENESIS; CHEMICAL INTERACTION; CONTROLLED STUDY; COVALENT BOND; DETOXIFICATION; DNA ADDUCT; MALE; METABOLIC ACTIVATION; NONHUMAN; RAT;

ANIMALIA;

EID: 0029946020     PISSN: 00092797     EISSN: None     Source Type: Journal    
DOI: 10.1016/0009-2797(95)03684-9     Document Type: Article

References (63)

1. G.N. Wogan, Aflatoxin carcinogenesis, in: H. Busch (Ed.), Methods in Cancer Research, Vol VII, Academic Press, New York, 1973, pp. 309-344.
2. R.C. Shank, Epidemiology of aflatoxin carcinogenesis, in: H.F. Kraybill and M.A. Mehlman (Eds.), Advances in Toxicology, Vol 3, Environmental Cancer, John Wiley and Sons, London, 1977, pp. 291-318.
3. 1 metabolite by hamster liver microsomes, FEBS Lett., 36 (1973) 261-264.
4. 1 2,3-oxide: evidence for its formation in rat liver in vivo and by human liver microsomes in vitro, Biochem. Biophys. Res. Commun., 60 (1974) 1036-1043.
5. 1: patterns of DNA adduct formation, removal and excretion in relation to carcinogenesis, Drug Metab. Rev., 13 (1982) 581-602.
6. R.C. Garner and C.N. Martin, Fungal toxins, aflatoxins and nucleic acids, in: P.L. Grover (Ed.), Chemical Carcinogens and DNA, CRC Press, Boca Raton, 1979, pp. 187-225.
7. 1 in vitro, Carcinogenesis, 5 (1984) 1359-1362.
8. 1 as detected in vitro in a simple fluorimetric assay, Chem.-Biol. Interact., 58 (1986) 173-186.
9. R.K. Bhattacharya, Interactions of dietary factors with chemical carcinogens, Proc. Nutr. Soc. India, 32 (1986) 55-67.
10. 1 in a microsome catalyzed reaction. Cancer Lett., 34 (1987) 213-220.
11. 1 by retinoyl-β-glucuronide, in S.B. Bhattacharjee (Ed.), Environment and Genome, Environmental Mutagen Society of India and Saha Institute of Nuclear Physics, Calcutta, 1991, pp. 345-353.
12. 1 carcinogenesis, Proc. Nutr. Soc. India, 37 (1991) 309-326.
13. 1 in vitro, Cancer Lett., 47 (1989) 127-132.
14. R.K. Bhattacharya, Mechanism of chemopreventive action of carotenoids at molecular level, in: S.V. Bhide and G.B. Maru (Eds.), Chemoprevention of Cancer, Omega Scientific Publishers, New Delhi, 1991, pp. 141-151.
15. 1 leading to activation and DNA adduct formation, Cancer Lett., 39 (1988) 85-91.
16. R.K. Bhattacharya, Flavonoids as modulators of carcinogenesis, in: N.P. Das (Ed.), Flavonoids in Biology and Medicine III, Current Issues in Flavonoid Research, National University of Singapore, Singapore, 1990, pp. 339-347.
17. R.K. Bhattachaya and P.F. Firozi, Interaction of polyphenols with microsomal monooxygenase during carcinogen activation, in: Groupe Polyphenol, Vol 15. Proc. XVth Int. Conf., Université Louis Pasteur, Strasbourg, 1990, pp. 179-184.
18. 1 activation in a reconstituted microsomal system, J. Biochem Toxicol., 10 (1995) 25-31.
19. P.R. Kuttan, P. Bhanumathi, K. Nirmala and M.C. George, Potential anticancer activity of turmeric (Curcuma longa), Cancer Lett., 29 (1985) 197-202.
20. M.-T. Huang, R.C. Smart, C.Q. Wong and A.H. Conney, Inhibitory effect of curcumin, chlorogenic acid, caffeic acid, and ferulic acid on tumor promotion in mouse skin by 12-O-tetradecanoylphorbol-13-acetate, Cancer Res., 48 (1988) 5941-5946.
21. M.A. Azuine, J.J. Kayal and S.V. Bhide, Protective role of aqueous turmeric extract against mutagenicity of direct-acting carcinogens as well as benzo[a]pyrene-induced genotoxicity and carcinogenicity, J. Cancer Res. Clin. Oncol., 118 (1992) 447-452.
22. M.A. Azuine and S.V. Bhide, Chemopreventive effect of turmeric against stomach and skin tumors induced by chemical carcinogens in Swiss mice, Nutr. Cancer, 17 (1992) 77-83.
23. M. Nagabhusan and S.V. Bhide, Curcumin as an inhibitor of cancer, J. Am. Coll. Nutr., 11 (1992) 192-198.
24. M.-T. Huang, E.E. Deschner, H.L. Newmark, Z.Y. Wang, T.A. Ferraro and A.H. Conney, Effect of dietary curcumin and ascorbyl palmitate on azoxymethanol-induced colonie epithelial cell proliferation and focal areas of dysplasia, Cancer Lett., 64 (1992) 117-121.
25. M.-T. Huang, Z.Y. Wang, C.A. Georgiadis, J.D. Laskin and A.H. Conney, Inhibitory effects of curcumin on tumor initiation by benzo[a]pyrene and 7,12-dimethylbenz[a]anthracene, Carcinogenesis, 13 (1992) 2183-2186.
26. C.W. Boone, V.E. Steele and G.J. Kelloff, Screening of chemopreventive (anticarcinogenic) compounds in rodents, Mutat. Res., 267 (1992) 251-255.
27. T. Tanaka, H. Makita, M. Ohnishi, Y. Hirose, A. Wang, H. Mori, K. Satoh, A. Hara and H. Ogawa, Chemoprevrention of 4-nitroquinoline-1-oxide-induced oral carcinogenesis by dietary curcumin and hesperidin: comparison with the protective effect of beta-carotene, Cancer Res., 54 (1994) 4653-4659.
28. M.-T. Huang, Y.R. Lou, W. Ma, H.L. Newmark, K.R. Reuhl and A.H. Conney, Inhibitory effects of dietary curcumin on forestomach, duodenal, and colon carcinogenesis in mice, Cancer Res., 54 (1994) 5841-5847.
29. K.B. Soni, A. Rajan and R. Kuttan, Reversal of aflatoxin induced liver damage by turmeric and curcumin, Cancer Lett., 66 (1992) 115-121.
30. L. Srinivas and V.K. Shalini, DNA damage by smoke: protection by turmeric and other inhibitors of ROS, Free Radical Biol. Med., 11 (1991) 277-283.
31. M.A. Mukundan, M.C. Chacko, V.V. Annapurna and K. Krishnaswamy, Effect of turmeric and curcumin on BP-DNA adducts, Carcinogeneis, 14 (1993) 493-496.
32. C.A. Shih and J.K. Lin, Inhibition of 8-hydroxydeoxyguanosine formation by curcumin in mouse fibroblast cells, Carcinogenesis, 14 (1993) 709-712.
33. 3[H]benzo[a]pyrene-DNA interaction in vitro in the presence of rat and mouse liver postmitochondial fraction, Cancer Lett., 73 (1993) 35-39.
34. S.D. Ghaisas and S.V. Bhide, In vitro studies on chemopreventive effect of Purnark against benzo[a]pyrene-induced chromosomal damage in human lymphocytes, Cell Biol. Int., 18 (1994) 21-27.
35. A.Y.H. Lu and W. Levin, Partial purification of cytochromes P450 and P448 from rat liver microsomes, Biochem. Biophys. Res. Commun., 46 (1972) 1334-1339.
36. C.M. Ardies, J.M. Lasker, B.P. Bloswick and C.S. Lieber, Purification of NADPH:cytochrome C (cytochrome P450) reductase from hamster liver microsomes by detergent extraction affinity chromatography, Anal. Biochem., 162 (1987) 39-46.
37. S.B. West, M.-T. Huang, G.T. Miwa and A.Y.H. Lu, A simple and rapid procedure for the purification of phenobarbital-inducible cytochrome P450 from rat liver microsomes, Arch. Biochem. Biophys., 193 (1979) 42-50.
38. D.R. Dutton, S.K. McMillan and A. Parkinson, Purification of rat liver microsomal cytochrome P450b without the use of non-ionic detergent, J. Biochem. Toxicol., 3 (1988) 131-145.
39. T. Omura and R. Sato, The carbon monoxide-binding pigment of liver microsomes, J. Biol. Chem., 239 (1964) 2370-2378.
40. A.H. Phillips and R.G. Langdon, Hepatic triphosphopyridine nucleotide-cytochrome C reductase: isolation, characterization and kinetic studies, J. Biol. Chem. 237 (1962) 2652-2660.
41. O.H. Lowry, N.J. Rosebrough, A.L. Farr and R.J. Randall, Protein measurement with the Folin phenol reagent, J. Biol. Chem., 193 (1951) 265-275.
42. 1 by reconstituted cytochrome P450 system in rat liver, Cancer Res., 42 (1980) 11120-1124.
43. V.S. Govindarajan, Turmeric chemistry, technology and quality, CRC Rev. Food. Sci. Nutr., 12 (1980) 199-301.
44. H.P. Ammon and M.A. Wahl, Pharmacology of Curcuma longa, Planta Med., 57 (1991) 1-7.
45. O.P. Sharma, Antioxidant activity of curcumin and related compounds, Biochem. Pharmacol., 25 (1976) 1811-1812.
46. V.K. Shalini and L. Srinivas, Lipid peroxide-induced DNA damage: protection by turmeric (Curcuma longa), Mol. Cell. Biochem., 77 (1987) 3-10.
47. B. Joe and B.R. Lokesh, Role of capsaicin, curcumin and dietary n-3 fatty acids in lowering the generation of reactive oxygen species in rat peritoneal macrophages, Biochim. Biophys. Acta, 1224 (1994) 255-263.
48. M. Subramanian, Sreejayan, M.N. Rao, T.P. Devasagayam and B.B. Singh, Diminution of singlet oxygen-induced DNA damage by curcumin and related antioxidants, Mutat. Res., 311 (1994) 249-255.
49. I.A. Donatus, S. Sardjoko and N.P. Vermeulen, Cytotoxic and cytoprotective activities of curcumin. Effects on paracetemol-induced cytotoxicity, lipid peroxidation and glutathione depletion in rat hepatocytes, Biochem. Pharmacol., 39 (1990) 1869-1875.
50. V.K. Shalini and L. Srinivas, Fuel smoke condensate induced DNA damage in human lymphocytes and protection by turmeric (Curcuma longa), Mol. Cell. Biochem., 95 (1990) 21-30.
51. S.K. Abraham, L. Sarma and P.C. Kesavan, Protective effects of chlorogenic acid, curcumin and beta-carotene against gamma-radiation-induced in vivo chromosomal damage, Mutat. Res., 303 (1993) 109-112.
52. M. Nagabhusan and S.V. Bhide, Nonmutagenicity of curcumin and its antimutagenic action versus chili and capsacin, Nutr. Cancer, 8 (1986) 201-210.
53. M. Nagabhusan, A.J. Amonkar and S.V. Bhide, In vitro antimutagenicity of curcumin against environmental mutagens, Food Chem. Toxicol., 25 (1987) 545-547.
54. K. Polasa, T.C. Raghuram, T.P. Krishna and K. Krishnaswamy, Effect of turmeric on urinary mutagens in smokers, Mutagenesis, 7 (1992) 107-109.
55. S. De Flora, H.S. Rosenkranz and G. Klopman, Structural basis of antimutagenicity of chemicals towards 4-nitroquinoline 1-oxide in Salmonella typhimurium, Mutagenesis, 9 (1994) 39-45.
56. A.C. Reddy and B.R. Lokesh, Studies on spice principles as antioxidants in the inhibition of lipid peroxidation of rat liver microsomes, Mol. Cell. Biochem., 111 (1992) 117-124.
57. K.K. Soudamini, M.C. Unnikrishnan, K.B. Soni and R. Kuttan, Inhibition of lipid peroxidation and cholesterol levels in mice by curcumin, Ind. J. Physiol. Pharmacol., 36 (1992) 239-243.
58. R.G. Mehta and R.C. Moon, Characterization of effective chemopreventive agents in mammary gland in vitro using an initiation-promotion protocol, Anticancer Res., 11 (1991) 593-596.
59. A.H. Conney, T. Lysz, T. Ferraro, T.F. Abidi, P.S. Manchand, J.D. Laskin and M.-T. Huang, Inhibitory effect of curcumin and some related dietary compounds on tumor promotion and arichidonic acid metabolism in mouse skin, Adv. Enzym. Regul., 31 (1991) 385-396.
60. C.V. Rao, B. Simi and B.S. Reddy, Inhibition by dietary curcumin of azoxymethane-induced ornithine decarboxylase, tyrosine protein kinase, arachidonic acid metabolism and aberrant crypt formation in the rat colon, Carcinogenesis, 14 (1993) 2219-2225.
61. J.Y. Liu and J.K. Lin, Inhibitory effects of curcumin on protein kinase C activity induced by 12-O-tetradecanoylphorbol-13-acetate in NIH 3T3 cells, Carcinogenesis, 14 (1993) 857-861.
62. Y.P. Lu, R.L. Chang, M.-T. Huang and A.H. Conney, Inhibitory effect of curcumin on 12-O-tetradecanoylphorbol-13-acetate-induced increase in ornithine decarboxylase mRNA in mouse epidermis, Carcinogenesis, 14 (1993) 293-297.
63. S.S. Kakar and D. Roy, Curcumin inhibits TPA induced expression of c-fos, c-jun and c-myc protooncogenes messenger RNAs in mouse skin, Cancer Lett., 87 (1994) 85-89.