Regulation of cytokinesis

Cellular and Molecular Life Sciences

Volumn 55, Issue 1, 1999, Pages 108-120

  Wolf, W A ^a   Chew, T L ^a   Chisholm, R L ^a  

^a NORTHWESTERN UNIVERSITY   (United States)

Author keywords

Contractile ring; Cytokinesis; Microtubules; Myosin; Rho

Indexed keywords

ACTIN; GUANINE NUCLEOTIDE BINDING PROTEIN; MYOSIN;

CYTOKINESIS; CYTOPLASM; HUMAN; MICROTUBULE; MITOSIS; NONHUMAN; PHOSPHORYLATION; REVIEW;

ACTINS; ANIMALS; CELL DIVISION; DICTYOSTELIUM; GTP-BINDING PROTEINS; MYOSINS; PHOSPHORYLATION;

EID: 0032986685     PISSN: 1420682X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s000180050274     Document Type: Review

References (87)

1. 1 Muhua L., Adames N. R., Murphy M. D., Shields C. R. and Cooper J. A. (1998) A cytokinesis checkpoint requiring the yeast homologue of an APC-binding protein. Nature 393: 487-491
2. 2 Yeh E., Skibbens R. V., Cheng J. W., Salmon E. D. and Bloom K. (1995) Spindle dynamics and cell cycle regulation of dynein in the budding yeast Saccharomyces cererisiae. J. Cell Biol. 130: 687-700
3. 3 Glotzer M. (1997) The mechanism and control of cytokinesis. Curr. Opin. Cell Biol. 9: 815-823
4. 4 Fishkind D. J. and Wang Y.-L. (1995) New horizons for cytokinesis. Curr. Opin. Cell Biol. 7: 23-31
5. 5 Satterwhite L. L. and Pollard T. D. (1992) Cytokinesis. Curr. Opin. Cell Biol. 4: 43-52
6. 6 Oegema K. and Mitchison T. J. (1997) Rappaport rules: cleavage furrow induction in animal cells. Proc. Natl. Acad. Sci. USA 94: 4817-4820
7. 7 Hall A. (1998) Rho GTPases and the actin cytoskeleton. Science 279: 509-514
8. 8 Amano M., Ito M., Kimura K., Fukata Y., Chihara K., Nakano T. et al. (1996) Phosphorylation and activation of myosin by Rho-associated kinase (Rho-kinase). J. Biol. Chem. 271: 20246-20249
9. 9 Chrzanowska-Wodnicka M. and Burridge K. (1996) Rho-stimulated contractility drives the formation of stress fibers and focal adhesions. J. Cell Biol. 133: 1403-1415
10. 10 Amano M., Chihara K., Kimura K., Fukata Y., Nakamura N., Matsuura Y. et al. (1997) Formation of actin stress fibers and focal adhesions enhanced by Rhokinase. Science 275: 1308-1311
11. 11 Kimura K., Ito M., Amano M., Chihara K., Fukata Y., Nakafuku M. et al. (1996) Regulation of myosin phosphatase by Rho and Rho-associated kinase (Rho-kinase). Science 273: 245-248
12. 12 Chrzanowska-Wodnicka M. and Burridge K. (1992) Rho, rac and the actin cytoskeleton. Bioessays 14: 777-778
13. 13 Lamarche N. and Hall A. (1994) GAPs for rho-related GTPases. Trends Genet. 10: 436-440
14. 14 Narumiya S. (1996) The small GTPase Rho: cellular functions and signal transduction. J. Biochem. (Tokyo) 120: 215-228
15. 15 Kishi K., Sasaki T., Kuroda S., Itoh T. and Takai Y. (1993) Regulation of cytoplasmic division of Xenopus embryo by rho p21 and its inhibitory GDP/GTP exchange protein (rho GDI). J. Cell Biol. 120: 1187-1195
16. 16 Rubin E. J., Gill D. M., Boquet P. and Popoff M. R. (1988) Functional modification of a 21-kilodalton G protein when ADPribosylated by exoenzyme C3 of Clostridium botulinum. Mol. Cell. Biol. 8: 418-426
17. 17 Mabuchi I., Hamaguchi Y., Fujimoto H., Morii N., Mishima M. and Narumiya S. (1993) A rho-like protein is involved in the organisation of the contractile ring in dividing sand dollar eggs. Zygote 1: 325-331
18. 18 Tukaishi K., Sasaki T., Kameyama T., Tsukita S. and Takai Y. (1995) Translocation of activated Rho from the cytoplasm to membrane ruffling area, cell-cell adhesion sites and cleavage furrows. Oncogene 11: 39-48
19. 19 Yamochi W., Tanaka K., Nonaka H., Maeda A., Musha T. and Takai Y. (1994) Growth site localization of Rho1 small GTP-binding protein and its involvement in bud formation in Saccharomyces cerevisiae. J. Cell Biol. 125: 1077-1093
20. 20 Drechsel D. N., Hyman A. A., Hall A. and Glotzer M. (1997) A requirement for Rho and Cdc42 during cytokinesis in Xenopus embryos. Curr. Biol. 7: 12-23
21. 21 Bluemink J. G. (1971) Cytokinesis and cytochalasin-induccd furrow regression in the first-cleavage zygote of Xenopus laevis. Z. Zellforsch. Mikrosk. Anat. 121: 102-126
22. 22 Luchtel D., Bluemink J. G. and de Laat S. W. (1976) The effect of injected cytochalasin B on filament organization in the cleaving egg of Xenopus laevis. J. Ultrastruct. Res. 54: 406-419
23. 23 Lippincott J. and Li R. (1998) Sequential assembly of myosin II, an IQGAP-like protein, and filamentous actin to a ring structure involved in budding yeast cytokinesis. J. Cell Biol. 140: 355-366
24. 24 Madaule P., Eda M., Watanabe N., Fujisawa K., Matsuoka T., Bito H. et al. (1998) Role of citron kinase as a target of the small GTPase Rho in cytokinesis. Nature 394: 491-494
25. 25 Daniels R. H., Hall P.S. and Bokoch G. M. (1998) Membrane-targeting of p21-activated kinase 1 (PAK1) induces neurite outgrowth from PC12 cells. EMBO J. 17: 754-764
26. 26 Dharmawardhane S., Sanders L. C., Martin S. S., Daniels R. H. and Bokoch G. M. (1997) Localization of p21-activated kinase 1 (PAKI) to pinocytic vesicles and cortical actin structures in stimulated cells. J. Cell Biol. 138: 1265-1278
27. 27 Zhao Z., Mauser E., Chen X., Chong C., Leung T. and Lim L. (1998) A conserved negative regulatory region in α-PAK: inhibition of PAK kinases reveals their morphological roles downstream of Cde42 and Rac1. Mol. Cell. Biol. 18: 2153-2163
28. 28 Sells M. A., Knaus U. G., Bagrodia S., Ambrose D. M., Bokoch G. M. and Chernoff J. (1997) Human p21-activated kinase (Pak1) regulates actin organization in mammalian cells. Curr. Biol. 7: 202-210
29. 29 Manser E., Huang H. Y., Loo T. H., Chen X. Q., Dong J. M., Leung T. et al. (1997) Expression of constitutively active alpha-PAK reveals effects of the kinase on actin and local complexes. Mol. Cell. Biol. 17: 1129-1143
30. 30 Chew T., Masaracchia R. and Wysolmerski R. (1998) Phosphorylation of myosin II regulatory light chain by a member of the p21-activated kinase (PAK) family, γ-PAK. J. Muscle Res. Cell Motil., in press
31. 31 Tuazon P. T., Skill J. T. and Traugh J. A. (1982) Phosphorylation of myosin light chain by protease activated kinase I. Biochem. Biophys. Res. Commun. 108: 910-917
32. 32 Tuazon P. T., Skill J. T. and Traugh J. A. (1982) Phosphorylation of myosin light chain by a protease-activated kinase from rabbit skeletal muscle. Eur. J. Biochem. 129: 205-209
33. 33 Tuazon P. T., Spanos W. C., Gump E. L., Monnig C. A. and Traugh J. A. (1997) Determinants for substrate phosphorylation by p21-activated protein kinase (gamma-PAK). Biochemistry 36: 16059-16064
34. 34 Ramos E., Wysolmerski R. B. and Masaracchia R. A. (1997) Myosin phosphorylation by human cdc42-dependent S6/H4 kinase/gammaPAK from placenta and lymphoid cells. Recept. Signal Transduct. 7: 99-110
35. 35 Brzeska H., Knaus U. G., Wang Z. Y., Bokoch G. M. and Korn E. D. (1997) p21-activated kinase has substrate specificity similar to Acanthamoeba myosin I heavy chain kinase and activates Acanthamoeba myosin I. Proc. Natl. Acad. Sci. USA 94: 1092-1095
36. 36 Rooney R. D., Tuazon P. T., Meek W. E., Carroll E. J., Hagen J. J., Gump E. L. et al. (1996) Cleavage arrest of early frog embryos by the G protein-activated protein kinase PAK I. J. Biol. Chem. 271: 21498-21504
37. 37 Larochelle D. A., Vithalani K. K. and De Lozanne A. (1997) Role of Dictyostelium racE in cytokinesis: mutational analysis and localization studies by use of green fluorescent protein. Mol. Biol. Cell 8: 935-944
38. 38 Tuxworth R. I., Cheetham J. L., Machesky L. M., Spiegelmann G. B., Weeks G. and Insall R. H. (1997) Dictyostelium RasG is required for normal motility and cytokinesis, but not growth. J. Cell Biol. 138: 605-614
39. 39 Chisholm R. L. (1997) Cytokinesis: a regulatory role for Ras-related proteins? Curr. Biol. 7: R648-650
40. 40 Gerald N., Dai J., Ting-Beall H. P. and De Lozanne A. (1998) A role for Dictyostelium racE in cortical tension and cleavage furrow progression. J. Cell Biol. 141: 483-492
41. 41 Frazier J. A. and Field C. M. (1997) Actin cytoskeleton: are FH proteins local organizers? Curr. Biol. 7: R414-417
42. 42 Swan K. A., Severson A. F., Carter J. C., Martin P. R., Schnabel H., Schnabel R. et al. (1998) cyk-1: a C. elegans FH gene required for a late step in embryonic cytokinesis. J. Cell Sci. 111: 2017-2027
43. 43 Epp J. A. and Chant J. (1997) An IQGAP-related protein controls actin-ring formation and cytokinesis in yeast. Curr. Biol. 7: 921-929
44. 44 Bashour A. M., Fullerton A. T., Hart M. J. and Bloom G. S. (1997) IQGAP1, a Rac-and Cdc42-binding protein, directly binds and cross-links microfilaments. J. Cell Biol. 137: 1555-1566
45. 45 Osman M. A. and Cerione R. A. (1998) Iqg1p, a yeast homologue of the mammalian IQGAPs, mediates cdc42p effects on the actin cytoskeleton. J. Cell Biol. 142: 443-455
46. 46 Fishkind D. J. and Wang Y. L. (1993) Orientation and three-dimensional organization of actin filaments in dividing cultured cells. J. Cell Biol. 123: 837-848
47. 47 Neujahr R., Heizer C., Albrecht R., Ecke M., Schwartz J. M., Weber I, et al. (1997) Three-dimensional patterns and redistribution of myosin II and actin in mitotic Dictyostelium cells. J. Cell Biol. 139: 1793-1804
48. 48 Moores S. L., Sabry J. H. and Spudich J. A. (1996) Myosin dynamics in live Dictyostelium cells. Proc. Natl. Acad. Sci. USA 93: 443-446
49. 49 Zang J. H., Cavet G., Sabry J. H., Wagner P., Moores S. L. and Spudich J. A. (1997) On the role of myosin-11 in cytokine-sis: division of Dictyostelium cells under adhesive and nonadhesive conditions. Mol. Biol. Cell 8: 2617-2629
50. 50 Sabry J. H., Moores S. L., Ryan S., Zang J. H. and Spudich J. A. (1997) Myosin heavy chain phosphorylation sites regulate myosin localization during cytokinesis in live cells. Mol. Biol. Cell 8: 2605-2615
51. 51 Yumura S. and Fukui Y. (1998) Spatiotemporal dynamics of actin concentration during cytokinesis and locomotion in Dictyostelium. J. Cell Sci. 111: 2097-2108
52. 52 Ostrow B. D., Chen P. and Chisholm R. L. (1994) Expression of a myosin regulatory light chain phosphorylation site mutant complements the cytokinesis and developmental defects of Dictyostelium RMLC null cells. J. Cell Biol. 127: 1945-1955
53. 53 Jordan P. and Karess R. (1997) Myosin light chain-activating phosphorylation sites are required for oogenesis in Drosoplila. J. Cell Biol. 139: 1805-1819
54. 54 Egelhoff T. T., Lee R. J. and Spudich J. A. (1993) Dictyostelium myosin heavy chain phosphorylation sites regulate myosin filament assembly and localization in vivo. Cell 75: 363-371
55. 55 Egelhoff T. T., Naismith T. V. and Brozovich F. V. (1996) Myosin-based cortical tension in Dictyostelium resolved into heavy and light chain-regulated components. J. Muscle Res. Cell Motil. 17: 269-274
56. cdc2: a mechanism for the timing of cytokinesis. J. Cell Biol. 118: 595-605
57. 57 DeBiasio R. L., LaRocca G. M., Post P. L. and Taylor D. L. (1996) Myosin II transport organization and phosphorylation: evidence for cortical flow/solation-contraction coupling during cytokinesis and cell locomotion. Mol. Biol. Cell 7: 1259-1282
58. 58 Matsumura F., Ono S., Yamakita Y., Totsukawa G. and Yamashiro S. (1998) Specific localization of serine 19 phosphorylated myosin II during cell locomotion and mitosis of cultured cells. J. Cell Biol. 140: 119-129
59. 59 Nishikawa M., Sellers J. R., Adelstein R. S. and Hidaka H. (1984) Protein kinase C modulates in vitro phosphorylation of the smooth muscle heavy meromyosin by myosin light chain kinase. J. Biol. Chem. 259: 8808-8814
60. 60 Bengur A. R., Robinson E. A., Appella E. and Sellers J. R. (1987) Sequence of the sites phosphorylated by protein kinase C in the smooth muscle myosin light chain. J. Biol. Chem. 262: 7613-7617
61. 61 Ikebe M. and Reardon S. (1990) Phosphorylation of bovine platelet myosin by protein kinase C. Biochemistry 29: 2713-2720
62. 62 Yamakita Y., Yamashiro S. and Matsumura F. (1994) In vivo phosphorylation of regulatory light chain of myosin II during mitosis of cultured cells. J. Cell Biol. 124: 129-137
63. 63 Mishima M. and Mabuchi I. (1996) Cell cycle-dependent phosphorylation of smooth muscle myosin light chain in sea urchin extracts. J. Biochem. 119: 906-913
64. 64 Totsukawa G., Himi-Nakamura E., Komatsu S., Iwata K., Tezuka A., Sakai H. et al. (1996) Mitosis-specific phosphorylalion of smooth muscle regulatory light chain of myosin II at Ser-1 and/or -2 and Thr-9 in sea urchin egg extract. Cell Struct. Fund. 21: 475-482
65. 65 De Lozanne A. and Spudich J. A. (1987) Disruption of the Dictyostelium myosin heavy chain gene by homologous recombination. Science 236: 1086-1091
66. 66 Knecht D. A. and Loomis W. F. (1987) Antisense RNA inactivation of myosin heavy chain gene expression in Dictyostelium discoideum. Science 236: 1081-1086
67. 67 Pollenz R. S., Chen T.-L. L., Trivinos-Lagos L. and Chisholm R. L. (1992) The Dictyostelium essential light chain is required for myosin function. Cell 69: 951-962
68. 68 Chen T. L., Kowalcyzk P. A., Ho G. and Chisholm R. L. (1995) Targeted disruption of the Dictyostelium myosin essential light chain gene produces cells defective in cytokinesis and morphogenesis. J. Cell Sci. 108: 3207-3218
69. 69 Chen P., Ostrow B. D., Tafuri S. R. and Chisholm R. L. (1994) Targeted disruption of the Dictyostelium RMLC gene produces cells defective in cytokinesis and development. J. Cell Biol. 127: 1933-1944
70. 70 Fukui Y., De Lozanne A. and Spudich J. A. (1990) Structure and function of the cytoskeleton of a Dictyostelium myosin-defective mutant. J. Cell Biol. 110: 367-378
71. 71 Neujahr R., Heizer C. and Gerisch G. (1997) Myosin II-independent processes in mitotic cells of Dictyostelium discoideum: redistribution of the nuclei, re-arrangement of the actin system and formation of the cleavage furrow. J. Cell Sci. 110: 123-137
72. 72 Faix J., Steinmetz M., Boves H., Kammerer R. A., Lottspeich F., Mintert U. et al. (1996) Cortexillins, major determinants of cell shape and size, are actin-bundling proteins with a parallel coiled-coil tail. Cell 86: 631-642
73. 73 Neujahr R., Albrecht R., Kohler J., Matzner M., Schwartz J. M., Westphal M. et al. (1998) Microtubule-mediated centrosome motility and the positioning of cleavage furrows in multinucleate myosin II-null cells. J. Cell Sci. 111: 1227-1240
74. 74 Burton K. and Taylor D. L. (1997) Traction forces of cytokinesis measured with optically modified elastic substrata. Nature 385: 450-454
75. 75 Mabuchi I. (1986) Biochemical aspects of cytokinesis. Int. Rev. Cytol. 101: 175-213
76. 76 Rappaport R. (1986) Establishment of the mechanism of cytokinesis in animal cells. Int. Rev. Cytol. 105: 245-281
77. 77 Bray D. and White J. G. (1988) Cortical flow in animal cells. Science 239: 883-888
78. 78 Wheatley S. P. and Wang Y. (1996) Midzone microtubule bundles are continuously required for cytokinesis in cultured epithelial cells. J. Cell Biol. 135: 981-989
79. 79 Harris A. K. and Gewalt S. L. (1989) Simulation testing of mechanisms for inducing the formation of the contractile ring in cytokinesis. J. Cell Biol. 109: 2215-2223
80. 80 Sawai T. (1998) Evidences For direct involvement of microtubules in cleavage furrow formation in newt eggs. Zoolog. Sci. 15: 51-56
81. 81 Raich W. B., Moran A. N., Rothman J. H. and Hardin J. (1998) Cytokinesis and midzone microtubule organization in Caenorhabditis elegans require the kinesin-like protein ZEN-4. Mol. Biol. Cell 9: 2037-2049
82. 82 Fishkind D. J., Silverman J. D. and Wang Y. L. (1996) Function of spindle microtubules in directing cortical movement and actin filament organization in dividing cultured cells. J. Cell Sci. 109: 2041-2051
83. 83 Canman J. C. and Bement W. M. (1997) Microtubules suppress actomyosin-based cortical flow in Xenopus oocytes. J. Cell Sci. 110: 1907-1917
84. 84 Bornens M., Paintrand M. and Celati C. (1989) The cortical microfilament system of lymphoblasts displays a periodic oscillatory activity in the absence of microtubules: implications for cell polarity. J. Cell Biol. 109: 1071-1083
85. 85 von Dassow G. and Schubiger G. (1994) How an actin network might cause fountain streaming and nuclear migration in the syncytial Drosophila embryo. J. Cell Biol. 127: 1637-1653
86. 86 Wheatley S. P., O'Connell C. B. and Wang Y. (1998) Inhibition of chromosomal separation provides insights into cleavage furrow stimulation in cultured epithelial cells. Mol. Biol. Cell 9: 2173-2184
87. 87 Giansanti M. G., Bonaccorsi S., Williams B., Williams E. V., Santolamazza C., Goldberg M. L. et al. (1998) Cooperative interactions between the central spindle and the contractile ring during Drosophila cytokinesis. Genes Dev. 12: 396-410