-
1
-
-
0028114740
-
Use of in vitro human metabolism studies in drug development, an industrial perspective
-
A. D. Rodrigues: Use of in vitro human metabolism studies in drug development, an industrial perspective. Biochem. Pharmacol. 48, 2147-2156 (1994).
-
(1994)
Biochem. Pharmacol.
, vol.48
, pp. 2147-2156
-
-
Rodrigues, A.D.1
-
2
-
-
0002888510
-
Human cytochrome P450 enzymes
-
(P. R. Ortiz de Montellano, ed.). Plenum Press, New York
-
F. P. Guengerich: Human cytochrome P450 enzymes. In "Cytochrome P450: Structure, Mechanism and Biochemistry" (P. R. Ortiz de Montellano, ed.). pp. 473-535. Plenum Press, New York, 1995.
-
(1995)
Cytochrome P450: Structure, Mechanism and Biochemistry
, pp. 473-535
-
-
Guengerich, F.P.1
-
3
-
-
0027328087
-
In vitro approaches can predict human drug metabolism
-
D. J. Birkett, P. I. Mackenzie, M. E. Veronese, and J. O. Miners: In vitro approaches can predict human drug metabolism. Trends Pharmacol. Sci. 14, 292-294 (1993).
-
(1993)
Trends Pharmacol. Sci.
, vol.14
, pp. 292-294
-
-
Birkett, D.J.1
Mackenzie, P.I.2
Veronese, M.E.3
Miners, J.O.4
-
4
-
-
0027756106
-
In vitro methods for assessing human hepatic drug metabolism: Their use in drug development
-
S. A. Wrighton, M. Vandenbranden, J. C. Stevens, L. A. Shipley, B. J. Ring, A. E. Rettie, and J. R. Cashman: In vitro methods for assessing human hepatic drug metabolism: their use in drug development. Drug Metab. Rev. 25, 453-484 (1993).
-
(1993)
Drug Metab. Rev.
, vol.25
, pp. 453-484
-
-
Wrighton, S.A.1
Vandenbranden, M.2
Stevens, J.C.3
Shipley, L.A.4
Ring, B.J.5
Rettie, A.E.6
Cashman, J.R.7
-
5
-
-
0027242397
-
Commentary: Validation and use of cloned, expressed human drug-metabolizing enzymes in heterologous cells for analysis of drug metabolism and drug-drug interactions
-
R. P. Remmel and B. Burchell: Commentary: validation and use of cloned, expressed human drug-metabolizing enzymes in heterologous cells for analysis of drug metabolism and drug-drug interactions. Biochem. Pharmacol. 46, 559-566 (1993).
-
(1993)
Biochem. Pharmacol.
, vol.46
, pp. 559-566
-
-
Remmel, R.P.1
Burchell, B.2
-
6
-
-
0027759647
-
Cytochrome P450 and monoclonal antibodies
-
H. V. Gelboin: Cytochrome P450 and monoclonal antibodies. Pharmacol. Rev. 45, 413-453 (1993).
-
(1993)
Pharmacol. Rev.
, vol.45
, pp. 413-453
-
-
Gelboin, H.V.1
-
7
-
-
0022541526
-
Antibodies as probes of cytochrome P450 isozymes
-
(J. J. Kocsis, D. J. Jollow, C. M. Witmer, J. O. Nelson, and R. Snyder, eds.). Plenum Press, New York
-
P. E. Thomas, L. M. Reik, S. L. Maines, S. Bandiera, D. E. Ryan, and W. Levin: Antibodies as probes of cytochrome P450 isozymes. In "Biological Reactive Intermediates III, Mechanisms of Action in Animal Models and Human Diseases" (J. J. Kocsis, D. J. Jollow, C. M. Witmer, J. O. Nelson, and R. Snyder, eds.), pp. 95-106. Plenum Press, New York, 1986.
-
(1986)
Biological Reactive Intermediates III, Mechanisms of Action in Animal Models and Human Diseases
, pp. 95-106
-
-
Thomas, P.E.1
Reik, L.M.2
Maines, S.L.3
Bandiera, S.4
Ryan, D.E.5
Levin, W.6
-
8
-
-
0026548096
-
Identification of the epitope of a monoclonal antibody which binds to several cytochromes P450 in the CYP1a subfamily
-
R. J. Edwards, D. Sesardic, B. P. Murray, A. M. Singleton, D. S. Davies, and A. R. Boobis: Identification of the epitope of a monoclonal antibody which binds to several cytochromes P450 in the CYP1A subfamily. Biochem. Pharmacol. 43, 1737-1746 (1992).
-
(1992)
Biochem. Pharmacol.
, vol.43
, pp. 1737-1746
-
-
Edwards, R.J.1
Sesardic, D.2
Murray, B.P.3
Singleton, A.M.4
Davies, D.S.5
Boobis, A.R.6
-
9
-
-
0027220308
-
Identification of the epitope of an anti-peptide antibody which binds to CYP1A2 in many species including man
-
R. J. Edwards, B. P. Murray, A. M. Singleton, S. Murray, D. S. Davies, and A. R. Boobis: Identification of the epitope of an anti-peptide antibody which binds to CYP1A2 in many species including man. Biochem. Pharmacol. 46, 213-220 (1993).
-
(1993)
Biochem. Pharmacol.
, vol.46
, pp. 213-220
-
-
Edwards, R.J.1
Murray, B.P.2
Singleton, A.M.3
Murray, S.4
Davies, D.S.5
Boobis, A.R.6
-
10
-
-
0029620446
-
Inhibitory and noninhibitory monoclonal antibodies to human cytochrome P450 3A3/4
-
H. V. Gelboin, K. W. Krausz, I. Goldfarb, J. T. M. Buters, S. K. Yang, F. J. Gonzalez, K. Korzekwa, and M. Shou: Inhibitory and noninhibitory monoclonal antibodies to human cytochrome P450 3A3/4. Biochem. Pharmacol. 50, 1841-1850 (1995).
-
(1995)
Biochem. Pharmacol.
, vol.50
, pp. 1841-1850
-
-
Gelboin, H.V.1
Krausz, K.W.2
Goldfarb, I.3
Buters, J.T.M.4
Yang, S.K.5
Gonzalez, F.J.6
Korzekwa, K.7
Shou, M.8
-
11
-
-
0026334526
-
Production and purification of antibodies against rat liver P450 enzymes
-
(M. R. Waterman and E. F. Johnson, eds.). Academic Press, San Diego
-
A. Parkinson, and B. Gemzik: Production and purification of antibodies against rat liver P450 enzymes. In "Methods in Enzymology" (M. R. Waterman and E. F. Johnson, eds.). Vol. 206. pp. 233-245. Academic Press, San Diego, 1991.
-
(1991)
Methods in Enzymology
, vol.206
, pp. 233-245
-
-
Parkinson, A.1
Gemzik, B.2
-
12
-
-
0029671175
-
Human cytochrome P450 expressed in Escherichia coli, production of specific antibodies
-
C. Belloc, S. Baird, J. Cosme, S. Lecoeur, J-C. Gautier, D. Challine, I. de Waziers, J.-P. Flinois, and P. H. Beaune: Human cytochrome P450 expressed in Escherichia coli, production of specific antibodies. Toxicology 106, 207-219 (1996).
-
(1996)
Toxicology
, vol.106
, pp. 207-219
-
-
Belloc, C.1
Baird, S.2
Cosme, J.3
Lecoeur, S.4
Gautier, J.-C.5
Challine, D.6
De Waziers, I.7
Flinois, J.-P.8
Beaune, P.H.9
-
13
-
-
0028865663
-
Identification of a common cytochrome P450 epitope near the conserved hemebinding peptide with antibodies raised against recombinant cytochrome P450 family 2 proteins
-
P. Soucek, M. V. Martin, Y. F. Ueng, and F. P. Guengerich: Identification of a common cytochrome P450 epitope near the conserved hemebinding peptide with antibodies raised against recombinant cytochrome P450 family 2 proteins. Biochem. 34, 16013-16021 (1995).
-
(1995)
Biochem.
, vol.34
, pp. 16013-16021
-
-
Soucek, P.1
Martin, M.V.2
Ueng, Y.F.3
Guengerich, F.P.4
-
14
-
-
0025311357
-
Synthetic peptide antigens elicit monoclonal and polyclonal antibodies to cytochrome P450 1A2
-
M. J. Myers, G. Liu, H. Miller, H. V. Gelboin, R. C. Robinson, and F. K. Friedman: Synthetic peptide antigens elicit monoclonal and polyclonal antibodies to cytochrome P450 1A2. Biochem. Biophys. Res. Commun. 169, 171-176 (1990).
-
(1990)
Biochem. Biophys. Res. Commun.
, vol.169
, pp. 171-176
-
-
Myers, M.J.1
Liu, G.2
Miller, H.3
Gelboin, H.V.4
Robinson, R.C.5
Friedman, F.K.6
-
15
-
-
0028851873
-
Anti-peptide antibodies to the P450 2D sub-family in rat, dog, and man
-
A. Nakamura, Y. Yamamoto, T. Tasaki, C. Sugimoto, M. Masuda, A. Kazusaka, and S. Fujita: Anti-peptide antibodies to the P450 2D sub-family in rat, dog, and man. Xenobiotica 25, 1103-1109 (1995).
-
(1995)
Xenobiotica
, vol.25
, pp. 1103-1109
-
-
Nakamura, A.1
Yamamoto, Y.2
Tasaki, T.3
Sugimoto, C.4
Masuda, M.5
Kazusaka, A.6
Fujita, S.7
-
16
-
-
0028840741
-
Purification and characterization of a dog cytochrome P450 isozyme belonging to the CYP2D subfamily and development of its anti-peptide antibody
-
A. Nakamura, Y. Yamamoto, T. Tasaki, C. Sugimoto, M. Masuda, A. Kazusaka, and S. Fujita: Purification and characterization of a dog cytochrome P450 isozyme belonging to the CYP2D subfamily and development of its anti-peptide antibody. Drug Metab. Dispos. 23, 1268-1273 (1995).
-
(1995)
Drug Metab. Dispos.
, vol.23
, pp. 1268-1273
-
-
Nakamura, A.1
Yamamoto, Y.2
Tasaki, T.3
Sugimoto, C.4
Masuda, M.5
Kazusaka, A.6
Fujita, S.7
-
17
-
-
0028796689
-
Anti-peptide antibodies targeted against specific regions of rat CYP2D1 and human CYP2D6
-
F. M. Laurenzana, S. L. Sorrels, and S. M. Owens: Anti-peptide antibodies targeted against specific regions of rat CYP2D1 and human CYP2D6. Drug Metab. Dispos. 23, 271-278 (1995).
-
(1995)
Drug Metab. Dispos.
, vol.23
, pp. 271-278
-
-
Laurenzana, F.M.1
Sorrels, S.L.2
Owens, S.M.3
-
18
-
-
0026349867
-
Isolation of P450 enzymes from human liver
-
(M. R. Waterman and E. F. Johnson, eds.). Academic Press, San Diego
-
J. L. Raucy and J. M. Lasker: Isolation of P450 enzymes from human liver. In "Methods in Enzymology" (M. R. Waterman and E. F. Johnson, eds.), vol. 206, pp. 557-587. Academic Press, San Diego, 1991.
-
(1991)
Methods in Enzymology
, vol.206
, pp. 557-587
-
-
Raucy, J.L.1
Lasker, J.M.2
-
19
-
-
0022186670
-
Measurement of protein using bicinchoninic acid
-
P. K. Smith, R. I. Krohn, G. T. Hermanson, A. K. Mallia, F. H. Gartnder, M. D. Provenzano, E. K. Fujimoto, N. M. Goeke, B. J. Olson, and D. C. Klenk: Measurement of protein using bicinchoninic acid. Anal. Biochem. 150, 76-85 (1985).
-
(1985)
Anal. Biochem.
, vol.150
, pp. 76-85
-
-
Smith, P.K.1
Krohn, R.I.2
Hermanson, G.T.3
Mallia, A.K.4
Gartnder, F.H.5
Provenzano, M.D.6
Fujimoto, E.K.7
Goeke, N.M.8
Olson, B.J.9
Klenk, D.C.10
-
20
-
-
78651165715
-
The carbon monoxide-binding pigment of liver microsomes. I. Evidence for its hemoprotein nature
-
T. Omura and R. Sato: The carbon monoxide-binding pigment of liver microsomes. I. Evidence for its hemoprotein nature. J. Biol. Chem. 239, 2370-2378 (1964).
-
(1964)
J. Biol. Chem.
, vol.239
, pp. 2370-2378
-
-
Omura, T.1
Sato, R.2
-
21
-
-
0022542951
-
Preparation of peptide-protein immunogens using N-succinimidyl bromoacetate as a heterobifunctional crosslinking reagent
-
M.S. Bernatowicz and G. R. Matsuedon: Preparation of peptide-protein immunogens using N-succinimidyl bromoacetate as a heterobifunctional crosslinking reagent. Anal. Biochem. 155, 95-102 (1986).
-
(1986)
Anal. Biochem.
, vol.155
, pp. 95-102
-
-
Bernatowicz, M.S.1
Matsuedon, G.R.2
-
22
-
-
0015173334
-
A method for producing specific antisera with small doses of immunogen
-
J. Vaitukaitis, J. B. Robbins, E. Nieschlag, and G. T. Ross: A method for producing specific antisera with small doses of immunogen. J. Clin. Endocrinol. 33, 988-991 (1971).
-
(1971)
J. Clin. Endocrinol.
, vol.33
, pp. 988-991
-
-
Vaitukaitis, J.1
Robbins, J.B.2
Nieschlag, E.3
Ross, G.T.4
-
23
-
-
0023147728
-
A simple, nonchromatographic procedure to purify immunoglobulins from serum and ascites fluid
-
M. M. McKinney and A. Parkinson: A simple, nonchromatographic procedure to purify immunoglobulins from serum and ascites fluid. J. Immunological Methods 96, 271-278 (1987).
-
(1987)
J. Immunological Methods
, vol.96
, pp. 271-278
-
-
McKinney, M.M.1
Parkinson, A.2
-
24
-
-
0003085947
-
Immunoassays
-
Cold Spring Harbor Laboratory. Cold Spring Harbor, NY
-
E. Harlow, and D. Lane: Immunoassays. In "Antibodies, a Laboratory Manual," Cold Spring Harbor Laboratory. Cold Spring Harbor, NY, pp. 555-612, 1988.
-
(1988)
Antibodies, a Laboratory Manual
, pp. 555-612
-
-
Harlow, E.1
Lane, D.2
-
25
-
-
0014949207
-
Cleavage of structural proteins during the assembly of the head of bacteriophage T4
-
U. K. Laemmli. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature (Lond.) 227, 680-685 (1970).
-
(1970)
Nature (Lond.)
, vol.227
, pp. 680-685
-
-
Laemmli, U.K.1
-
26
-
-
0009482260
-
Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: Procedure and some applications
-
H. Towbin, S. Theophil, and J. Gordon: Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications. Proc. Natl. Acad. Sci. USA 76, 4350-4354 (1979).
-
(1979)
Proc. Natl. Acad. Sci. USA
, vol.76
, pp. 4350-4354
-
-
Towbin, H.1
Theophil, S.2
Gordon, J.3
-
27
-
-
0028858960
-
Cytochrome P450 inhibitors, evaluation of specificities in the in vitro metabolism of therapeutic agents by human liver microsomes
-
D. J. Newton, R. W. Wang, and A. Y. H. Lu: Cytochrome P450 inhibitors, evaluation of specificities in the in vitro metabolism of therapeutic agents by human liver microsomes. Drug Metab. Dispos. 23, 154-158 (1995).
-
(1995)
Drug Metab. Dispos.
, vol.23
, pp. 154-158
-
-
Newton, D.J.1
Wang, R.W.2
Lu, A.Y.H.3
-
28
-
-
0027364928
-
Specificity of substrate and inhibitor probes for human cytochromes P450 1A1 and 1A2
-
W. Tassaneeyakul, D. J. Birkett, M. E. Veronese, M. E. Mcmanus, R. H. Tukey, L. C. Quattrochi, H. V. Gelboin, and J. O. Miners: Specificity of substrate and inhibitor probes for human cytochromes P450 1A1 and 1A2. J. Pharmacol. Exp. Ther. 265, 401-407 (1993).
-
(1993)
J. Pharmacol. Exp. Ther.
, vol.265
, pp. 401-407
-
-
Tassaneeyakul, W.1
Birkett, D.J.2
Veronese, M.E.3
Mcmanus, M.E.4
Tukey, R.H.5
Quattrochi, L.C.6
Gelboin, H.V.7
Miners, J.O.8
-
29
-
-
0023355128
-
Hepatic metabolism of tolbutamide: Characterization of the form of cytochrome P450 involved in methyl hydroxylation and relationship to in vivo disposition
-
R. G. Knodell, S. D. Hall, G. R. Wilkinson, and F. P. Guengerich: Hepatic metabolism of tolbutamide: characterization of the form of cytochrome P450 involved in methyl hydroxylation and relationship to in vivo disposition. J. Pharmacol. Exp. Ther. 241, 1112-1119 (1987).
-
(1987)
J. Pharmacol. Exp. Ther.
, vol.241
, pp. 1112-1119
-
-
Knodell, R.G.1
Hall, S.D.2
Wilkinson, G.R.3
Guengerich, F.P.4
-
30
-
-
0026324040
-
Bufuralol, dextromethorphan and debrisoquine as prototype Substrates for human P450IID6
-
(M. R. Waterman and E. F. Johnson, eds), Academic Press, San Diego
-
T. Kronbach: Bufuralol, dextromethorphan and debrisoquine as prototype Substrates for human P450IID6. In "Methods in Enzymology" (M. R. Waterman and E. F. Johnson, eds), vol. 206, pp. 509-517, Academic Press, San Diego, 1991.
-
(1991)
Methods in Enzymology
, vol.206
, pp. 509-517
-
-
Kronbach, T.1
-
31
-
-
0025223625
-
Hydroxylation of chlorzoxazone as a specific probe for human liver cytochrome P450IIE1
-
R. Peter, R. Bocker, P. H. Beaune, M. Iwasaki, F. P. Guengerich, and C. S. Yang: Hydroxylation of chlorzoxazone as a specific probe for human liver cytochrome P450IIE1. Chem. Res. Toxicol. 3, 566-573 (1990).
-
(1990)
Chem. Res. Toxicol.
, vol.3
, pp. 566-573
-
-
Peter, R.1
Bocker, R.2
Beaune, P.H.3
Iwasaki, M.4
Guengerich, F.P.5
Yang, C.S.6
-
33
-
-
0000448982
-
Prediction of protein antigenic determinants from amino acid sequences
-
T. P. Hopp, and K. R. Woods: Prediction of protein antigenic determinants from amino acid sequences. Proc. Natl. Acad. Sci. USA 78, 3824-3828 (1981).
-
(1981)
Proc. Natl. Acad. Sci. USA
, vol.78
, pp. 3824-3828
-
-
Hopp, T.P.1
Woods, K.R.2
-
34
-
-
0022249654
-
Induction of hepatitis a virus-neutralizing antibody by a virus-specific synthetic peptide
-
E. A. Emini, J. V. Hughes, D. S. Perlow, and J. Boger: Induction of hepatitis A virus-neutralizing antibody by a virus-specific synthetic peptide. J. Virol. 55, 836-839 (1985).
-
(1985)
J. Virol.
, vol.55
, pp. 836-839
-
-
Emini, E.A.1
Hughes, J.V.2
Perlow, D.S.3
Boger, J.4
-
35
-
-
0029073965
-
Anti-peptide antibodies against over-lapping sequences differentially inhibit human CYP2D6
-
A. Cribb, C. Nuss, and R. Wang: Anti-peptide antibodies against over-lapping sequences differentially inhibit human CYP2D6. Drug Metab. Dispos. 23, 671-675 (1995).
-
(1995)
Drug Metab. Dispos.
, vol.23
, pp. 671-675
-
-
Cribb, A.1
Nuss, C.2
Wang, R.3
-
36
-
-
0024498616
-
Identification and location of α-helices in mammalian cytochromes P450
-
R. J. Edwards, B. P. Murray, A. R. Boobis, and D. S. Davies: Identification and location of α-helices in mammalian cytochromes P450. Biochem. 28, 3762-3770(1989).
-
(1989)
Biochem.
, vol.28
, pp. 3762-3770
-
-
Edwards, R.J.1
Murray, B.P.2
Boobis, A.R.3
Davies, D.S.4
-
37
-
-
0026542989
-
Substrate recognition sites in cytochrome P450 family 2 (CYP2) protein inferred from comparative analyses of amino acid and coding nucleotide sequences
-
O. Gotoh: Substrate recognition sites in cytochrome P450 family 2 (CYP2) protein inferred from comparative analyses of amino acid and coding nucleotide sequences. J. Biol. Chem. 267, 83-90 (1992).
-
(1992)
J. Biol. Chem.
, vol.267
, pp. 83-90
-
-
Gotoh, O.1
-
38
-
-
0023765220
-
Antibodies to a synthetic peptide that react specifically with a common surface region on two hydrocarbon-inducible isoenzymes of cytochrome P450 in the rat
-
R. J. Edwards, A. M. Singleton, D. Sesardic, A. R. Boobis, and D. S. Davies: Antibodies to a synthetic peptide that react specifically with a common surface region on two hydrocarbon-inducible isoenzymes of cytochrome P450 in the rat. Biochem. Pharmacol. 37, 3735-3741 (1988).
-
(1988)
Biochem. Pharmacol.
, vol.37
, pp. 3735-3741
-
-
Edwards, R.J.1
Singleton, A.M.2
Sesardic, D.3
Boobis, A.R.4
Davies, D.S.5
-
39
-
-
0025304025
-
An anti-peptide antibody targeted to a specific region of rat cytochrome P450IA2 inhibits enzyme activity
-
R. J. Edwards, A. M. Singleton, B. P. Murray, D. Sesardic, K. J. Rich, D. S. Davies, and A. R. Boobis: An anti-peptide antibody targeted to a specific region of rat cytochrome P450IA2 inhibits enzyme activity. Biochm. J. 266, 497-504 (1990).
-
(1990)
Biochm. J.
, vol.266
, pp. 497-504
-
-
Edwards, R.J.1
Singleton, A.M.2
Murray, B.P.3
Sesardic, D.4
Rich, K.J.5
Davies, D.S.6
Boobis, A.R.7
-
40
-
-
0027463893
-
An inhibitory monoclonal anti-protein antibody and an anti-peptide antibody share an epitope on rat cytochrome P450 enzymes CYP1A1 and CYP1A2
-
R. J. Edwards, B. P. Murray, S. Murray, A. M. Singleton, D. S. Davies, and A. R. Boobis: An inhibitory monoclonal anti-protein antibody and an anti-peptide antibody share an epitope on rat cytochrome P450 enzymes CYP1A1 and CYP1A2. Biochim. Biophys. Acta 1161, 38-46 (1993).
-
(1993)
Biochim. Biophys. Acta
, vol.1161
, pp. 38-46
-
-
Edwards, R.J.1
Murray, B.P.2
Murray, S.3
Singleton, A.M.4
Davies, D.S.5
Boobis, A.R.6
-
41
-
-
0025787855
-
Immunocytochemical distribution of aromatase cytochrome P450 in the rat brain using peptide-generated polyclonal antibodies
-
M. K. Sanghera, E. R. Simpson, M. J. McPhaul, G. Kozlowski, A. J. Conley, and E. D. Lephart: Immunocytochemical distribution of aromatase cytochrome P450 in the rat brain using peptide-generated polyclonal antibodies. Endocrinology 129, 2834-2844 (1991).
-
(1991)
Endocrinology
, vol.129
, pp. 2834-2844
-
-
Sanghera, M.K.1
Simpson, E.R.2
McPhaul, M.J.3
Kozlowski, G.4
Conley, A.J.5
Lephart, E.D.6
-
42
-
-
0030063547
-
Epitope mapping studies with human anti-cytochrome P450 3A antibodies
-
J. S. Leeder, A. Gaedigk, X. Lu, and V. A. Cook: Epitope mapping studies with human anti-cytochrome P450 3A antibodies. Mol. Pharmacol. 49, 234-243 (1996).
-
(1996)
Mol. Pharmacol.
, vol.49
, pp. 234-243
-
-
Leeder, J.S.1
Gaedigk, A.2
Lu, X.3
Cook, V.A.4
-
43
-
-
0025303638
-
Patients with type II autoimmune hepatitis express functionally intact cytochrome P450 db1 that is inhibited by LKM-1 autoantibodies in vitro but not in vivo
-
M. Manns, U. Zanger, G. Gerken, K. F. Sullivan, K. H. M. Z. Buschenfelde, U. A. Meyer, and M. Eichelbaum: Patients with type II autoimmune hepatitis express functionally intact cytochrome P450 db1 that is inhibited by LKM-1 autoantibodies in vitro but not in vivo. Hepatology 12, 127-132 (1990).
-
(1990)
Hepatology
, vol.12
, pp. 127-132
-
-
Manns, M.1
Zanger, U.2
Gerken, G.3
Sullivan, K.F.4
Buschenfelde, K.H.M.Z.5
Meyer, U.A.6
Eichelbaum, M.7
-
44
-
-
0025992973
-
LKM-1 autoantibodies recognize a short linear sequence in P450IID6, a cytochrome P450 monooxygenase
-
M. P. Manns, K. J. Griffin, K. F. Sullivan, and E. F. Johnson: LKM-1 autoantibodies recognize a short linear sequence in P450IID6, a cytochrome P450 monooxygenase. J. Clin. Invest. 88, 1370-1378 (1991).
-
(1991)
J. Clin. Invest.
, vol.88
, pp. 1370-1378
-
-
Manns, M.P.1
Griffin, K.J.2
Sullivan, K.F.3
Johnson, E.F.4
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