Polymer/inhibitor conjugates a promising strategy to overcome the enzymatic barrier to perorally administered (poly)peptide drugs?

S.T.P. Pharma Sciences

Volumn 9, Issue 1, 1999, Pages 83-92

  Bernkop Schnurch A ^a  

^a UNIVERSITY OF VIENNA   (Austria)

Author keywords

Competitive inhibitor conjugates; Complexing agent conjugates Polymer; Drug delivery systems; Inhibitor conjugates Polymer; Peroral(poly)peptide application; Polymer; Polymer inhibitor conjugates of the mixed type

Indexed keywords

ANTIPAIN; BOWMAN BIRK INHIBITOR; CHITOSAN; CHYMOSTATIN; EDETIC ACID; ENZYME INHIBITOR; POLYACRYLIC ACID; POLYMER; POLYPEPTIDE; PROTEINASE;

ADHESION; CHEMICAL STRUCTURE; CONJUGATION; CONTROLLED DRUG RELEASE; COVALENT BOND; DRUG DELIVERY SYSTEM; ENZYME INHIBITOR COMPLEX; INTESTINE EPITHELIUM; ORAL DRUG ADMINISTRATION; REVIEW;

EID: 0032883740     PISSN: 11571489     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

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