-
1
-
-
0023888769
-
2EDTA, and aprotinin on rectal, nasal, and buccal insulin delivery
-
2EDTA, and aprotinin on rectal, nasal, and buccal insulin delivery. Pharm. Res., 5, 305-308.
-
(1988)
Pharm. Res.
, vol.5
, pp. 305-308
-
-
Aungst, B.J.1
Rogers, N.J.2
-
2
-
-
0030765867
-
Strategien zur peroralen Applikation von Peptid- Und Proteinwirkstoffen
-
Bernkop-Schnürch, A. (1997) Strategien zur peroralen Applikation von Peptid- und Proteinwirkstoffen. Sci. Pharm., 65, 61-81.
-
(1997)
Sci. Pharm.
, vol.65
, pp. 61-81
-
-
Bernkop-Schnürch, A.1
-
3
-
-
0032473473
-
The use of inhibitory agents to overcome the enzymatic barrier to perorally administered therapeutic peptides and proteins
-
in press
-
Bernkop-Schnürch, A. (1998) The use of inhibitory agents to overcome the enzymatic barrier to perorally administered therapeutic peptides and proteins. J. Control. Release, in press.
-
(1998)
J. Control. Release
-
-
Bernkop-Schnürch, A.1
-
4
-
-
0031056746
-
Synthesis and evaluation of a modified mucoadhesive polymer protecting from α-chymotrypsinic degradation
-
Bernkop-Schnürch, A. and Apprich, I. (1997) Synthesis and evaluation of a modified mucoadhesive polymer protecting from α-chymotrypsinic degradation. Int. J. Pharm., 146, 247-254.
-
(1997)
Int. J. Pharm.
, vol.146
, pp. 247-254
-
-
Bernkop-Schnürch, A.1
Apprich, I.2
-
5
-
-
0030581134
-
Novel bioadhesive drug delivery system protecting (poly)peptides from gastric enzymatic degradation
-
Bernkop-Schnürch, A. and Dundalek, K. (1996) Novel bioadhesive drug delivery system protecting (poly)peptides from gastric enzymatic degradation. Int. J. Pharm., 138, 75-83.
-
(1996)
Int. J. Pharm.
, vol.138
, pp. 75-83
-
-
Bernkop-Schnürch, A.1
Dundalek, K.2
-
6
-
-
1842415952
-
Development and analysis of a polymer protecting from luminal enzymatic degradation caused by α-chymotrypsin
-
Bernkop-Schnürch, A. and Göckel, N.C. (1997) Development and analysis of a polymer protecting from luminal enzymatic degradation caused by α-chymotrypsin. Drug Dev. Ind. Pharm., 23, 733-740.
-
(1997)
Drug Dev. Ind. Pharm.
, vol.23
, pp. 733-740
-
-
Bernkop-Schnürch, A.1
Göckel, N.C.2
-
7
-
-
0032472305
-
Mucoadhesive polymers as platforms for peroral peptide delivery and absorption: Synthesis and evaluation of different chitosan-EDTA conjugates
-
Bernkop-Schnürch, A. and Krajicek, M.E. (1998) Mucoadhesive polymers as platforms for peroral peptide delivery and absorption: synthesis and evaluation of different chitosan-EDTA conjugates. J. Control. Release, 50, 215-223.
-
(1998)
J. Control. Release
, vol.50
, pp. 215-223
-
-
Bernkop-Schnürch, A.1
Krajicek, M.E.2
-
8
-
-
0030900713
-
Development and in vitro evaluation of systems to protect peptide drugs from aminopeptidase N
-
Bernkop-Schnürch, A. and Marschütz, M. (1997) Development and in vitro evaluation of systems to protect peptide drugs from aminopeptidase N. Pharm. Res., 14, 181-185.
-
(1997)
Pharm. Res.
, vol.14
, pp. 181-185
-
-
Bernkop-Schnürch, A.1
Marschütz, M.2
-
9
-
-
0031901490
-
Intestinal peptide and protein delivery: Novel bioadhesive drug carrier-matrix shielding from enzymatic attack
-
in press
-
Bernkop-Schnürch, A. and Pasta, M. (1998) Intestinal peptide and protein delivery: novel bioadhesive drug carrier-matrix shielding from enzymatic attack. J. Pharm. Sci., in press.
-
(1998)
J. Pharm. Sci.
-
-
Bernkop-Schnürch, A.1
Pasta, M.2
-
10
-
-
0031915514
-
Synthesis and in vitro evaluation of chitosan-EDTA-protease-inhibitor conjugates which might be useful in oral delivery of peptides and proteins
-
Bernkop-Schnürch, A. and Scerbe-Saiko, A. (1998) Synthesis and in vitro evaluation of chitosan-EDTA-protease-inhibitor conjugates which might be useful in oral delivery of peptides and proteins. Pharm. Res., 15, 267-273.
-
(1998)
Pharm. Res.
, vol.15
, pp. 267-273
-
-
Bernkop-Schnürch, A.1
Scerbe-Saiko, A.2
-
11
-
-
0030813427
-
Development and in vitro evaluation of a drug delivery system protecting from trypsinic degradation
-
Bernkop-Schnürch, A., Bratengeyer, I. and Valenta, C. (1997a) Development and in vitro evaluation of a drug delivery system protecting from trypsinic degradation. Int. J. Pharm., 157, 17-25.
-
(1997)
Int. J. Pharm.
, vol.157
, pp. 17-25
-
-
Bernkop-Schnürch, A.1
Bratengeyer, I.2
Valenta, C.3
-
12
-
-
0030943636
-
Modified mucoadhesive polymers for the peroral administration of mainly elastase degradable therapeutic (poly)peptides
-
Bernkop-Schnürch, A., Schwarz, G.H. and Kratzel, M. (1997b) Modified mucoadhesive polymers for the peroral administration of mainly elastase degradable therapeutic (poly)peptides. J. Control. Release, 47, 113-121.
-
(1997)
J. Control. Release
, vol.47
, pp. 113-121
-
-
Bernkop-Schnürch, A.1
Schwarz, G.H.2
Kratzel, M.3
-
13
-
-
0030740816
-
Novel bioadhesive chitosan-EDTA conjugate protects leucine enkephalin from degradation by aminopeptidase N
-
Bernkop-Schnürch, A., Paikl, Ch. and Valenta, C. (1997c) Novel bioadhesive chitosan-EDTA conjugate protects leucine enkephalin from degradation by aminopeptidase N. Pharm. Res., 14, 917-922.
-
(1997)
Pharm. Res.
, vol.14
, pp. 917-922
-
-
Bernkop-Schnürch, A.1
Paikl, Ch.2
Valenta, C.3
-
14
-
-
0032516229
-
Basic studies on bioadhesive delivery systems for peptide and protein drugs
-
in press
-
Bernkop-Schnürch, A., Humenberger, C. and Valenta, C. (1998) Basic studies on bioadhesive delivery systems for peptide and protein drugs. Int. J. Pharm., in press.
-
(1998)
Int. J. Pharm.
-
-
Bernkop-Schnürch, A.1
Humenberger, C.2
Valenta, C.3
-
15
-
-
0022017412
-
The Bowman-Birk inhibitor
-
Birk, Y. (1985) The Bowman-Birk inhibitor. Int. J. Peptide Protein Res., 25, 113-131.
-
(1985)
Int. J. Peptide Protein Res.
, vol.25
, pp. 113-131
-
-
Birk, Y.1
-
16
-
-
0016175428
-
Human liver aminopeptidase. Role of metal ions in mechanism of action
-
Garner, Ch.W. and Behal, F.J. (1974) Human liver aminopeptidase. Role of metal ions in mechanism of action. Biochemistry, 13, 3227-3233.
-
(1974)
Biochemistry
, vol.13
, pp. 3227-3233
-
-
Garner, Ch.W.1
Behal, F.J.2
-
17
-
-
0030839517
-
N-trimethyl chitosan chloride as a potential absorption enhancer across mucosal surfaces - In vitro evaluation in intestinal epithelial cells (CACO-2)
-
Kotzé, A.F., Lueßen, H.L., Deleeuw, B.J., de Boer, B.G., Verhoef, J.C. and Junginger, E.H. (1997) N-trimethyl chitosan chloride as a potential absorption enhancer across mucosal surfaces - in vitro evaluation in intestinal epithelial cells (CACO-2). Pharm. Res., 14, 1197-1202.
-
(1997)
Pharm. Res.
, vol.14
, pp. 1197-1202
-
-
Kotzé, A.F.1
Lueßen, H.L.2
Deleeuw, B.J.3
De Boer, B.G.4
Verhoef, J.C.5
Junginger, E.H.6
-
18
-
-
0028609750
-
Bioadhesion technologies for the delivery of peptide and protein drugs to the gastrointestinal tract
-
Lehr, C.-M. (1994) Bioadhesion technologies for the delivery of peptide and protein drugs to the gastrointestinal tract. Crit. Rev. Ther. Drug. Car. Syst., 11, 119-160.
-
(1994)
Crit. Rev. Ther. Drug. Car. Syst.
, vol.11
, pp. 119-160
-
-
Lehr, C.-M.1
-
19
-
-
0028788346
-
Mucoadhesive polymers in the peroral peptide drug delivery: II. Carbomer and polycarbophil are potent inhibitors of the intestinal proteolytic enzyme trypsin
-
Lueßen, H.L., Verhoef, J.C., Borchard, G., Lehr, C.-M., de Boer, A.G. and Junginger, H.E. (1995) Mucoadhesive polymers in the peroral peptide drug delivery: II. Carbomer and polycarbophil are potent inhibitors of the intestinal proteolytic enzyme trypsin. Pharm. Res., 12, 1293-1298.
-
(1995)
Pharm. Res.
, vol.12
, pp. 1293-1298
-
-
Lueßen, H.L.1
Verhoef, J.C.2
Borchard, G.3
Lehr, C.-M.4
De Boer, A.G.5
Junginger, H.E.6
-
20
-
-
17344382638
-
Mucoadhesive polymers in peroral peptide drug delivery. I. Influence of mucoadhesive excipients on the proteolytic activity of intestinal enzymes
-
Lueßen, H.L., de Leeuw, B.J., Pérard, D., Lehr, C.-M., de Boer, A.G., Verhoef, J.C. and Junginger, E.H. (1996) Mucoadhesive polymers in peroral peptide drug delivery. I. Influence of mucoadhesive excipients on the proteolytic activity of intestinal enzymes. Eur. J. Pharm. Sci., 4, 117-128.
-
(1996)
Eur. J. Pharm. Sci.
, vol.4
, pp. 117-128
-
-
Lueßen, H.L.1
De Leeuw, B.J.2
Pérard, D.3
Lehr, C.-M.4
De Boer, A.G.5
Verhoef, J.C.6
Junginger, E.H.7
-
21
-
-
0031018133
-
Mucoadhesive polymers in peroral peptide drug delivery. IV. Polycarbophil and chitosan are potent enhancers of peptide transport across intestinal mucosae in vitro
-
Lueßen, H.L., Rentel, C-O., Kotzé, A.F., Lehr, C.-M., de Boer, A.G., Verhoef, J.C. and Junginger, H.E. (1997) Mucoadhesive polymers in peroral peptide drug delivery. IV. Polycarbophil and chitosan are potent enhancers of peptide transport across intestinal mucosae in vitro. J. Control. Release, 45, 15-23.
-
(1997)
J. Control. Release
, vol.45
, pp. 15-23
-
-
Lueßen, H.L.1
Rentel, C.-O.2
Kotzé, A.F.3
Lehr, C.-M.4
De Boer, A.G.5
Verhoef, J.C.6
Junginger, H.E.7
-
22
-
-
0029968525
-
Proteinase inhibitors induce selective stimulation of human trypsin and chymotrypsin secretion
-
Reseland, J.E., Holm, H., Jacobsen, M.B., Jenssen, T.G. and Hanssen, L.E. (1996) Proteinase inhibitors induce selective stimulation of human trypsin and chymotrypsin secretion. Hum. Clin. Nutr., 126, 634-642.
-
(1996)
Hum. Clin. Nutr.
, vol.126
, pp. 634-642
-
-
Reseland, J.E.1
Holm, H.2
Jacobsen, M.B.3
Jenssen, T.G.4
Hanssen, L.E.5
-
23
-
-
0015501044
-
Isolation and properties of complexes of the Bowman-Birk soybean inhibitor with trypsin and chymotrypsin
-
Seidl, D.S. and Liener, I.E. (1972) Isolation and properties of complexes of the Bowman-Birk soybean inhibitor with trypsin and chymotrypsin. J. Biol. Chem., 247, 3533-3538.
-
(1972)
J. Biol. Chem.
, vol.247
, pp. 3533-3538
-
-
Seidl, D.S.1
Liener, I.E.2
-
24
-
-
0031745232
-
Chitosan-EDTA conjugate: A novel polymer for topical used gels
-
Valenta, C., Christen, B. and Bernkop-Schnürch, A. (1998) Chitosan-EDTA conjugate: A novel polymer for topical used gels. J. Pharm. Pharmacol., 50, 445-452.
-
(1998)
J. Pharm. Pharmacol.
, vol.50
, pp. 445-452
-
-
Valenta, C.1
Christen, B.2
Bernkop-Schnürch, A.3
-
25
-
-
0028657017
-
Enzymatic barriers for GI peptide and protein delivery
-
Woodley, J.F. (1994) Enzymatic barriers for GI peptide and protein delivery. Crit. Rev. Ther. Drug Car. Syst., 11, 61-95.
-
(1994)
Crit. Rev. Ther. Drug Car. Syst.
, vol.11
, pp. 61-95
-
-
Woodley, J.F.1
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