메뉴 건너뛰기




Volumn 4, Issue 3, 1997, Pages 147-156

Complement interactions with amyloid-β1-42: A nidus for inflammation in AD brains

Author keywords

Alzheimer's disease; Anaphylatoxin; C3 convertase; Inflammation; Microglia; Opsonization; Phagocytosis

Indexed keywords


EID: 0000911605     PISSN: 13506129     EISSN: None     Source Type: Journal    
DOI: 10.3109/13506129709014379     Document Type: Article
Times cited : (36)

References (54)
  • 1
    • 0343268699 scopus 로고
    • Immunology and Medicine Series, ed. K. Whaley. Dordrecht: Kluwer Academic Publishers
    • McPhaden AR and Whaley K, The Complement System and Inflammation. Immunology and Medicine Series, ed. K. Whaley. Vol. 18. 1992, Dordrecht: Kluwer Academic Publishers. 17-36
    • (1992) The Complement System and Inflammation , vol.18 , pp. 17-36
    • McPhaden, A.R.1    Whaley, K.2
  • 2
    • 0019782188 scopus 로고
    • Binding reaction between the third human complement protein and small molecules
    • Law SK, Minich TM and Levine RP (1981). Binding reaction between the third human complement protein and small molecules. Biochemistry 20, 7457-7463
    • (1981) Biochemistry , vol.20 , pp. 7457-7463
    • Law, S.K.1    Minich, T.M.2    Levine, R.P.3
  • 3
    • 0018288596 scopus 로고
    • Evidence for an ester linkage between the labile binding site of C3b and receptive surfaces
    • Law SK, Lichtenberg NA and Levine RP (1979). Evidence for an ester linkage between the labile binding site of C3b and receptive surfaces. J Immunol 123, 1388-1394
    • (1979) J Immunol , vol.123 , pp. 1388-1394
    • Law, S.K.1    Lichtenberg, N.A.2    Levine, R.P.3
  • 4
    • 0024425302 scopus 로고
    • Complement membrane attack on nucleated cells: Resistance, recovery and non-lethal effects
    • Morgan BP (1989). Complement membrane attack on nucleated cells: resistance, recovery and non-lethal effects. Biochem J 264, 1-14
    • (1989) Biochem J , vol.264 , pp. 1-14
    • Morgan, B.P.1
  • 5
    • 0025992992 scopus 로고
    • Reactions of the immune system in chronic degenerative neurological diseases
    • McGeer PL, McGeer EG, Kawamata T, Yamada T and Akiyama H (1991). Reactions of the immune system in chronic degenerative neurological diseases. Can J Neurol Sci 18, 376-379
    • (1991) Can J Neurol Sci , vol.18 , pp. 376-379
    • McGeer, P.L.1    McGeer, E.G.2    Kawamata, T.3    Yamada, T.4    Akiyama, H.5
  • 7
    • 0030250852 scopus 로고    scopus 로고
    • The role of complement and activated microglia in the pathogenesis of Alzheimer's Disease
    • Eikelenboom P and Veerhuis R (1996). The role of complement and activated microglia in the pathogenesis of Alzheimer's Disease. Neurobiol Aging 17, 673-680
    • (1996) Neurobiol Aging , vol.17 , pp. 673-680
    • Eikelenboom, P.1    Veerhuis, R.2
  • 9
    • 0025002021 scopus 로고
    • Acute phase proteins are present in amorphous plaques in the cerebral but not in the cerebellar cortex of patients with Alzheimer's disease
    • Rozemuller JM, Stam FC and Eikelenboom P (1990). Acute phase proteins are present in amorphous plaques in the cerebral but not in the cerebellar cortex of patients with Alzheimer's disease. Neurosci Lett 119, 75-78
    • (1990) Neurosci Lett , vol.119 , pp. 75-78
    • Rozemuller, J.M.1    Stam, F.C.2    Eikelenboom, P.3
  • 11
    • 0027158642 scopus 로고
    • Association cortex, cerebellum, and serum concentrations of C1q and factor B in Alzheimer's disease
    • Brachova L, Lue LF, Schultz J, el Rashidy T and Rogers J (1993). Association cortex, cerebellum, and serum concentrations of C1q and factor B in Alzheimer's disease. Brain Res Mol Brain Res 18, 329-334
    • (1993) Brain Res Mol Brain Res , vol.18 , pp. 329-334
    • Brachova, L.1    Lue, L.F.2    Schultz, J.3    El Rashidy, T.4    Rogers, J.5
  • 14
    • 0028178458 scopus 로고
    • Beta-amyloid activates complement by binding to a specific region of the collagen-like domain of the C1qA chain
    • Jiang H, Burdick D, Glabe CG, Cotman CW and Tenner AJ (1994). Beta-amyloid activates complement by binding to a specific region of the collagen-like domain of the C1qA chain. J Immunol 152, 5050-5059
    • (1994) J Immunol , vol.152 , pp. 5050-5059
    • Jiang, H.1    Burdick, D.2    Glabe, C.G.3    Cotman, C.W.4    Tenner, A.J.5
  • 15
    • 0029795517 scopus 로고    scopus 로고
    • Inflammation, Aβ deposition, and neurofibrillary tangle formation as correlates of Alzheimer's Disease neurodegeneration
    • Lue L-E, Brachova L, Civin H and Rogers J (1996). Inflammation, Aβ deposition, and neurofibrillary tangle formation as correlates of Alzheimer's Disease neurodegeneration. J Neuropath Exp Neurol 55, 1083-1088
    • (1996) J Neuropath Exp Neurol , vol.55 , pp. 1083-1088
    • Lue, L.-E.1    Brachova, L.2    Civin, H.3    Rogers, J.4
  • 16
    • 0027332081 scopus 로고
    • β-Amyloid-(1-42) is a major component of cerebrovascular amyloid deposits: Implications for the pathology of Alzheimer disease
    • Roher AE, Lowenson JD, Clarke S, Woods AS, Cotter RJ, Cowing E and Ball MJ (1993). β-Amyloid-(1-42) is a major component of cerebrovascular amyloid deposits: implications for the pathology of Alzheimer disease. Proc Natl Acad Sci 90, 10836-10840
    • (1993) Proc Natl Acad Sci , vol.90 , pp. 10836-10840
    • Roher, A.E.1    Lowenson, J.D.2    Clarke, S.3    Woods, A.S.4    Cotter, R.J.5    Cowing, E.6    Ball, M.J.7
  • 17
    • 0029923520 scopus 로고    scopus 로고
    • Association of Aβ40-positive senile plaques with microglial cells in the brains of patients with Alzheimer's disease and in non-demented aged individuals
    • Fukumoto H, Asami Odaka A, Suzuki N and Iwatsubo T (1996). Association of Aβ40-positive senile plaques with microglial cells in the brains of patients with Alzheimer's disease and in non-demented aged individuals. Neurodegeneration 5, 13-17
    • (1996) Neurodegeneration , vol.5 , pp. 13-17
    • Fukumoto, H.1    Asami Odaka, A.2    Suzuki, N.3    Iwatsubo, T.4
  • 18
    • 0028863201 scopus 로고
    • Microglial cells and amyloid beta protein (Aβ) deposition; association with Aβ 40-containing plaques
    • Mann DM, Iwatsubo T, Fukumoto H, Ihara Y, Odaka A and Suzuki N (1995). Microglial cells and amyloid beta protein (Aβ) deposition; association with Aβ 40-containing plaques. Acta Neuropathol Berl 90, 472-477
    • (1995) Acta Neuropathol Berl , vol.90 , pp. 472-477
    • Mann, D.M.1    Iwatsubo, T.2    Fukumoto, H.3    Ihara, Y.4    Odaka, A.5    Suzuki, N.6
  • 19
    • 0028923898 scopus 로고
    • Complement and cytokine gene expression in cultured microglial derived from postmortem human brains
    • Walker DG, Kim SU and McGeer PL (1995). Complement and cytokine gene expression in cultured microglial derived from postmortem human brains. J Neurosci Res 40, 478-93
    • (1995) J Neurosci Res , vol.40 , pp. 478-493
    • Walker, D.G.1    Kim, S.U.2    McGeer, P.L.3
  • 20
    • 0029053689 scopus 로고
    • Complement expression in human brain. Biosynthesis of terminal pathway components and regulators in human glial cells and cell lines
    • Gasque P, Fontaine M and Morgan BP (1995). Complement expression in human brain. Biosynthesis of terminal pathway components and regulators in human glial cells and cell lines. J Immunol 154, 4726-33
    • (1995) J Immunol , vol.154 , pp. 4726-4733
    • Gasque, P.1    Fontaine, M.2    Morgan, B.P.3
  • 21
    • 0029079605 scopus 로고
    • Complement biosynthesis in the central nervous system
    • Barnum SR (1995). Complement biosynthesis in the central nervous system. Crit Rev Oral Biol Med 6, 132-146
    • (1995) Crit Rev Oral Biol Med , vol.6 , pp. 132-146
    • Barnum, S.R.1
  • 24
    • 0004552774 scopus 로고
    • Intravenous FUT-175 inhibits complement activation in the cerebrospinal fluid and vasospasm-related delayed ischemic neurological deficit following subarachnoid hemorrhage
    • ed. J.M. Findley. Amsterdam: Elsevier
    • Yanamoto H, Kikuchi H, Ishikawa J, Shimizu Y, Sato M, Tokuriki Y, Okamoto S, Matsumoto M, Matsumoto K and Nakamura M (1993). Intravenous FUT-175 inhibits complement activation in the cerebrospinal fluid and vasospasm-related delayed ischemic neurological deficit following subarachnoid hemorrhage. Cerebral Vasospams, ed. J.M. Findley. Amsterdam: Elsevier. 431-434
    • (1993) Cerebral Vasospams , pp. 431-434
    • Yanamoto, H.1    Kikuchi, H.2    Ishikawa, J.3    Shimizu, Y.4    Sato, M.5    Tokuriki, Y.6    Okamoto, S.7    Matsumoto, M.8    Matsumoto, K.9    Nakamura, M.10
  • 26
    • 0001733723 scopus 로고
    • Thioflavine T interaction with amyloid β-sheet structures
    • LeVine H (1995). Thioflavine T interaction with amyloid β-sheet structures. Amyloid 2, 1-6
    • (1995) Amyloid , vol.2 , pp. 1-6
    • LeVine, H.1
  • 27
    • 0344535425 scopus 로고    scopus 로고
    • Complement labeling of aggregated Aβ1-42 by normal human serum involves the classical and alternative pathways
    • eds. K Iqbal; B Winblad, T Nishmura, M Takeda, and H Wisniewski. John Wiley & Sons Ltd.
    • Watson MD, Roher AE, Kim KS, Spiegel K and Emmerling MR. Complement labeling of aggregated Aβ1-42 by normal human serum involves the classical and alternative pathways. Alzheimer's Disease: Biology, Diagnosis and Therapeutics, eds. K Iqbal; B Winblad, T Nishmura, M Takeda, and H Wisniewski. 1997. John Wiley & Sons Ltd. 365-373
    • (1997) Alzheimer's Disease: Biology, Diagnosis and Therapeutics , pp. 365-373
    • Watson, M.D.1    Roher, A.E.2    Kim, K.S.3    Spiegel, K.4    Emmerling, M.R.5
  • 28
    • 0022657826 scopus 로고
    • A reexamination of the role of magnesium in the human alternative pathway of complement
    • Pryzdial EL and Isenman DE (1986). A reexamination of the role of magnesium in the human alternative pathway of complement. Mol Immunol 23, 87-96
    • (1986) Mol Immunol , vol.23 , pp. 87-96
    • Pryzdial, E.L.1    Isenman, D.E.2
  • 29
    • 2642600862 scopus 로고
    • Covalent binding and hemolytic activity of complement proteins
    • Law SK, Lichtenberg NA and Levine RP (1980). Covalent binding and hemolytic activity of complement proteins. Proc Natl Acad Sci 77, 7194-7198
    • (1980) Proc Natl Acad Sci , vol.77 , pp. 7194-7198
    • Law, S.K.1    Lichtenberg, N.A.2    Levine, R.P.3
  • 30
    • 0345176684 scopus 로고
    • Evidence for presence of an internal thiolester bond in third component of human complement
    • Tack BF, Harrison RA, Janatova J, Thomas ML and Prahl JW (1980). Evidence for presence of an internal thiolester bond in third component of human complement. Proc Natl Acad Sci 77, 5764-5768
    • (1980) Proc Natl Acad Sci , vol.77 , pp. 5764-5768
    • Tack, B.F.1    Harrison, R.A.2    Janatova, J.3    Thomas, M.L.4    Prahl, J.W.5
  • 31
    • 0021265581 scopus 로고
    • Pharmacological studies of FUT-175, nafamstat mesilate. I. Inhibition of protease activity in in vitro and in vivo experiments
    • Aoyama T, Ino Y, Ozeki M, Oda M, Sato T, Koshiyama Y, Suzuki S and Fujita M (1984). Pharmacological studies of FUT-175, nafamstat mesilate. I. Inhibition of protease activity in in vitro and in vivo experiments. Jpn J Pharmacol 35, 203-227
    • (1984) Jpn J Pharmacol , vol.35 , pp. 203-227
    • Aoyama, T.1    Ino, Y.2    Ozeki, M.3    Oda, M.4    Sato, T.5    Koshiyama, Y.6    Suzuki, S.7    Fujita, M.8
  • 32
    • 0031444893 scopus 로고    scopus 로고
    • Inhibiting the formation of classical C3-convertase on the Alzheimer β-amyloid peptide
    • in press
    • Emmerling MR, Spiegel K and Watson MD (1997). Inhibiting the formation of classical C3-convertase on the Alzheimer β-amyloid peptide. Immunopharm in press
    • (1997) Immunopharm
    • Emmerling, M.R.1    Spiegel, K.2    Watson, M.D.3
  • 33
    • 0344103963 scopus 로고    scopus 로고
    • The Alzheimer's Disease Aβ peptide generates C5a and sC5b-9 via direct activation of both complement pathways
    • Bradt BM, Bixby TS and Cooper NR (1996). The Alzheimer's Disease Aβ peptide generates C5a and sC5b-9 via direct activation of both complement pathways. Mol Immunol 33, 27
    • (1996) Mol Immunol , vol.33 , pp. 27
    • Bradt, B.M.1    Bixby, T.S.2    Cooper, N.R.3
  • 34
    • 0019854795 scopus 로고
    • Nucleophilic modification of human complement protein C3: Correlation of conformational changes with acquisition of C3bi-like functional properties
    • Iseman DE, Kells DIC, Cooper NR, Muller-Eberhard HJ and Pangburn MK. (1981). Nucleophilic modification of human complement protein C3: Correlation of conformational changes with acquisition of C3bi-like functional properties. Biochemistry 20, 4458-4467
    • (1981) Biochemistry , vol.20 , pp. 4458-4467
    • Iseman, D.E.1    Kells, D.I.C.2    Cooper, N.R.3    Muller-Eberhard, H.J.4    Pangburn, M.K.5
  • 36
    • 0028179341 scopus 로고
    • Chemical characterization of A beta 17-42 peptide, a component of diffuse amyloid deposits of Alzheimer disease
    • Gowing E, Roher AE, Woods AS, Cotter RJ, Chaney M, Little SP and Ball MJ (1994). Chemical characterization of A beta 17-42 peptide, a component of diffuse amyloid deposits of Alzheimer disease. J Biol Chem 269, 10987-10990
    • (1994) J Biol Chem , vol.269 , pp. 10987-10990
    • Gowing, E.1    Roher, A.E.2    Woods, A.S.3    Cotter, R.J.4    Chaney, M.5    Little, S.P.6    Ball, M.J.7
  • 37
    • 0030276575 scopus 로고    scopus 로고
    • Aβ40 is a major form of ß-amyloid in non-human primates
    • Gearing M, Tigges J, Mori H and Mirra SS (1996). Aβ40 is a major form of ß-amyloid in non-human primates. Neurobiol Aging 17, 903-908
    • (1996) Neurobiol Aging , vol.17 , pp. 903-908
    • Gearing, M.1    Tigges, J.2    Mori, H.3    Mirra, S.S.4
  • 38
    • 0026176190 scopus 로고
    • Homology of the amyloid beta protein precursor in monkey and human supports a primate model for beta amyloidosis in Alzheimer's disease
    • Podlisny MB, Tolan DR and Selkoe DJ (1991). Homology of the amyloid beta protein precursor in monkey and human supports a primate model for beta amyloidosis in Alzheimer's disease. Am J Pathol 138, 1423-1435
    • (1991) Am J Pathol , vol.138 , pp. 1423-1435
    • Podlisny, M.B.1    Tolan, D.R.2    Selkoe, D.J.3
  • 39
    • 1542444221 scopus 로고    scopus 로고
    • Activation of the classical complement cascade by the amyloid β-peptide (Aβ) is a function of the aggregation state of Aβ
    • Webster S, Rogers J, Bradt B, Bixby T and Cooper NR (1996). Activation of the classical complement cascade by the amyloid β-peptide (Aβ) is a function of the aggregation state of Aβ Mol Immunol 33, 113
    • (1996) Mol Immunol , vol.33 , pp. 113
    • Webster, S.1    Rogers, J.2    Bradt, B.3    Bixby, T.4    Cooper, N.R.5
  • 40
    • 0031031747 scopus 로고    scopus 로고
    • Aspartate residue 7 in amyloid β-protein is critical for classical complement pathway activation: Implications for Alzheimer's Disease pathogenesis
    • Velazquez P, Cribbs DH, Poulos TL, and Tenner AJ (1996). Aspartate residue 7 in amyloid β-protein is critical for classical complement pathway activation: Implications for Alzheimer's Disease pathogenesis. Nat Med 3, 77-79
    • (1996) Nat Med , vol.3 , pp. 77-79
    • Velazquez, P.1    Cribbs, D.H.2    Poulos, T.L.3    Tenner, A.J.4
  • 41
    • 0027988116 scopus 로고
    • Surfactant properties of Alzheimer's A beta peptides and the mechanism of amyloid aggregation
    • Soreghan B, Kosmoski J and Glabe C (1994). Surfactant properties of Alzheimer's A beta peptides and the mechanism of amyloid aggregation. J Biol Chem 269, 28551-28554
    • (1994) J Biol Chem , vol.269 , pp. 28551-28554
    • Soreghan, B.1    Kosmoski, J.2    Glabe, C.3
  • 42
    • 0028491538 scopus 로고
    • Microvascular pathology and vascular basement membrane components in Alzheimer's disease
    • Perlmutter LS (1994). Microvascular pathology and vascular basement membrane components in Alzheimer's disease. Mol Neurobiol 9, 33-40
    • (1994) Mol Neurobiol , vol.9 , pp. 33-40
    • Perlmutter, L.S.1
  • 47
    • 0026070054 scopus 로고
    • Effects of injected Alzheimer beta-amyloid cores in rat brain
    • Frautschy SA, Baird A and Cole GM (1991). Effects of injected Alzheimer beta-amyloid cores in rat brain. Proc Natl Acad Sci 88, 8362-8366
    • (1991) Proc Natl Acad Sci , vol.88 , pp. 8362-8366
    • Frautschy, S.A.1    Baird, A.2    Cole, G.M.3
  • 48
    • 0026635173 scopus 로고
    • Phagocytosis and deposition of vascular beta-amyloid in rat brains injected with Alzheimer beta-amyloid
    • Frautschy SA, Cole GM and Baird A (1992). Phagocytosis and deposition of vascular beta-amyloid in rat brains injected with Alzheimer beta-amyloid. Am J Pathol 140, 1389-1399
    • (1992) Am J Pathol , vol.140 , pp. 1389-1399
    • Frautschy, S.A.1    Cole, G.M.2    Baird, A.3
  • 51
    • 0028863749 scopus 로고
    • Identification and characterization of the complement C5a anaphylatoxin receptor on human astrocytes
    • Gasque P, Chan P, Fontaine M, Ischenko A, Lamacz M, Gotze O and Morgan BP (1995). Identification and characterization of the complement C5a anaphylatoxin receptor on human astrocytes. J Immunol 155, 4882-4889
    • (1995) J Immunol , vol.155 , pp. 4882-4889
    • Gasque, P.1    Chan, P.2    Fontaine, M.3    Ischenko, A.4    Lamacz, M.5    Gotze, O.6    Morgan, B.P.7
  • 52
    • 0029119287 scopus 로고
    • Expression of the receptors for the C5a anaphylatoxin, interleukin-8 and FMLP by human astrocytes and microglia
    • Lacy M, Jones J, Whittemore SR, Haviland DL, Wetsel RA and Barnum SR (1995). Expression of the receptors for the C5a anaphylatoxin, interleukin-8 and FMLP by human astrocytes and microglia. J Neuroimmunol 61, 71-78
    • (1995) J Neuroimmunol , vol.61 , pp. 71-78
    • Lacy, M.1    Jones, J.2    Whittemore, S.R.3    Haviland, D.L.4    Wetsel, R.A.5    Barnum, S.R.6
  • 53
    • 0025733411 scopus 로고
    • Aggregation-related toxicity of synthetic beta-amyloid protein in hippocampal cultures
    • Pike CJ, Walencewicz AJ, Glabe CG and Cotman CW (1991). Aggregation-related toxicity of synthetic beta-amyloid protein in hippocampal cultures. Eur J Pharmacol 207, 367-368
    • (1991) Eur J Pharmacol , vol.207 , pp. 367-368
    • Pike, C.J.1    Walencewicz, A.J.2    Glabe, C.G.3    Cotman, C.W.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.