IMP dehydrogenase: Structural aspects of inhibitor binding

Current Medicinal Chemistry

Volumn 6, Issue 7, 1999, Pages 519-536

  Goldstein, Barry M ^a   Colby, Thomas D ^a  

^a UNIVERSITY OF ROCHESTER MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

5 ETHYNYL 4 IMIDAZOLECARBOXAMIDE 1 RIBOSIDE; ENZYME INHIBITOR; INOSINATE DEHYDROGENASE; INOSINATE DEHYDROGENASE INHIBITOR; INOSINE PHOSPHATE; ISOENZYME; MIZORIBINE; MYCOPHENOLIC ACID; MYCOPHENOLIC ACID 2 MORPHOLINOETHYL ESTER; NICOTINAMIDE ADENINE DINUCLEOTIDE; RIBAVIRIN; TIAZOFURIN; UNCLASSIFIED DRUG;

ARTICLE; CANCER CHEMOTHERAPY; COMPLEX FORMATION; DRUG BINDING; DRUG BINDING SITE; DRUG DESIGN; DRUG INDUCED DISEASE; DRUG SPECIFICITY; DRUG STRUCTURE; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME BINDING; ENZYME CONFORMATION; ENZYME INHIBITION; HUMAN; IMMUNOSUPPRESSIVE TREATMENT; MOLECULAR MODEL; NONHUMAN; SPECIES DIFFERENCE; STRUCTURE ANALYSIS;

AMINO ACIDS; ANIMALS; BINDING SITES; BORRELIA BURGDORFERI GROUP; CRICETINAE; CRYSTALLOGRAPHY, X-RAY; DRUG DESIGN; HUMANS; IMP DEHYDROGENASE; MODELS, BIOLOGICAL; MODELS, MOLECULAR; PROTEIN BINDING; PROTEIN CONFORMATION; STREPTOCOCCUS PYOGENES; TRITRICHOMONAS FOETUS;

EID: 0032806574     PISSN: 09298673     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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