Inactivation of inosine 5′-monophosphate dehydrogenase by the antiviral agent 5-ethynyl-1-β-D-ribofuranosylimidazole-4-carboxamide 5′-monophosphate

Biochemistry

Volumn 35, Issue 1, 1996, Pages 95-101

  Wang, Wen ^a   Papov, Vladimir V ^b   Minakawa, Noriaki ^c   Matsuda, Akira ^c   Biemann, Klaus ^b   Hedstrom, Lizbeth ^a  

^a BRANDEIS UNIVERSITY   (United States)

^b MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^c HOKKAIDO UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

5 ETHYNYL 4 IMIDAZOLECARBOXAMIDE 1 RIBOSIDE; INOSINATE DEHYDROGENASE;

ARTICLE; CHEMICAL REACTION; COVALENT BOND; DNA SEQUENCE; ENZYME ACTIVITY; ENZYME DENATURATION; ENZYME INACTIVATION; ESCHERICHIA COLI; HYDROLYSIS; NONHUMAN; NUCLEOTIDE METABOLISM; PRIORITY JOURNAL; RNA TRANSLATION;

AMINO ACID SEQUENCE; ANTIVIRAL AGENTS; BINDING SITES; ENZYME INHIBITORS; ESCHERICHIA COLI; HUMANS; IMP DEHYDROGENASE; ISOENZYMES; KINETICS; MATHEMATICS; MOLECULAR SEQUENCE DATA; PEPTIDE FRAGMENTS; PROTEIN BINDING; PROTEIN DENATURATION; RIBONUCLEOTIDES; SPECTROPHOTOMETRY, ULTRAVIOLET;

BACTERIA (MICROORGANISMS); ESCHERICHIA COLI;

EID: 0030047103     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi951499q     Document Type: Article

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