메뉴 건너뛰기




Volumn 8, Issue 8, 1997, Pages 943-954

Intracranial administration of adenovirus expressing HSV-TK in combination with ganciclovir produces a dose-dependent, self-limiting inflammatory response

Author keywords

[No Author keywords available]

Indexed keywords

ANTIVIRUS AGENT; GANCICLOVIR; THYMIDINE KINASE; VIRUS ENZYME;

EID: 0031010215     PISSN: 10430342     EISSN: None     Source Type: Journal    
DOI: 10.1089/hum.1997.8.8-943     Document Type: Article
Times cited : (51)

References (37)
  • 1
    • 0027477148 scopus 로고
    • Direct in vivo gene transfer to ependymal cells in the central nervous system using recombinant adenovirus vectors
    • BAJOCCHI, G., FELDMAN, S.H., and CRYSTAL, R.G. (1993). Direct in vivo gene transfer to ependymal cells in the central nervous system using recombinant adenovirus vectors. Nature Genet. 3, 229-234.
    • (1993) Nature Genet. , vol.3 , pp. 229-234
    • Bajocchi, G.1    Feldman, S.H.2    Crystal, R.G.3
  • 2
    • 0029035825 scopus 로고
    • Attenuation of stroke size in rats using an adenoviral vector to induce overexpression of interleukin-1 receptor antagonist in brain
    • BETZ, A.L., YANG, G.Y., and DAVIDSON, B.L. (1995). Attenuation of stroke size in rats using an adenoviral vector to induce overexpression of interleukin-1 receptor antagonist in brain. J. Cerebral Blood Flow Metab. 15, 547-551.
    • (1995) J. Cerebral Blood Flow Metab. , vol.15 , pp. 547-551
    • Betz, A.L.1    Yang, G.Y.2    Davidson, B.L.3
  • 4
    • 0022575463 scopus 로고
    • Photoradiation therapy: Current status and applications in the treatment of brain tumors
    • CHENG, M.K., MCKEAN, J., BOISVERT, D., and TULIP, J. (1986). Photoradiation therapy: current status and applications in the treatment of brain tumors. Surg. Neurol. 25, 423-435.
    • (1986) Surg. Neurol. , vol.25 , pp. 423-435
    • Cheng, M.K.1    Mckean, J.2    Boisvert, D.3    Tulip, J.4
  • 5
    • 0026772206 scopus 로고
    • In vivo gene transfer with retroviral vector-producer cells for treatment of experimental brain tumors
    • CULVER, K.W., RAM, Z., WALLBRIDGE, S., ISHII, H., OLDFIELD, E.H., and BLAESE, R.M. (1992). In vivo gene transfer with retroviral vector-producer cells for treatment of experimental brain tumors. Science 256, 1550-1552.
    • (1992) Science , vol.256 , pp. 1550-1552
    • Culver, K.W.1    Ram, Z.2    Wallbridge, S.3    Ishii, H.4    Oldfield, E.H.5    Blaese, R.M.6
  • 6
    • 0027522920 scopus 로고
    • A model system for in vivo gene transfer into the central nervous system using an adenoviral vector
    • DAVIDSON, B.L., ALLEN, E.D., KOZARSKY, K.F., WILSON, J.M., and ROESSLER, B.L. (1993). A model system for in vivo gene transfer into the central nervous system using an adenoviral vector. Nature Genet. 3, 219-223.
    • (1993) Nature Genet. , vol.3 , pp. 219-223
    • Davidson, B.L.1    Allen, E.D.2    Kozarsky, K.F.3    Wilson, J.M.4    Roessler, B.L.5
  • 8
    • 0002676117 scopus 로고    scopus 로고
    • Gene-based therapy
    • J.G. Hardman, L.E. Limbird, P.B. Molinoff, and R.W. Ruddon, eds. (McGraw-Hill, New York)
    • ECK, S.L., and WILSON, J.M. (1996). Gene-based therapy. In The Pharmacological Basis of Therapeutics. J.G. Hardman, L.E. Limbird, P.B. Molinoff, and R.W. Ruddon, eds. (McGraw-Hill, New York), pp. 94-96.
    • (1996) The Pharmacological Basis of Therapeutics , pp. 94-96
    • Eck, S.L.1    Wilson, J.M.2
  • 10
    • 0028246338 scopus 로고
    • Ablation of E2A in recombinant adenoviruses improves transgene persistence and decreases inflammatory response in mouse liver
    • ENGELHARDT, J.F., YE, X., DORANZ, B., and WILSON, J.M. (1994). Ablation of E2A in recombinant adenoviruses improves transgene persistence and decreases inflammatory response in mouse liver. Proc. Natl. Acad. Sci. USA 91, 6196-6200.
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 6196-6200
    • Engelhardt, J.F.1    Ye, X.2    Doranz, B.3    Wilson, J.M.4
  • 15
    • 0023835077 scopus 로고
    • Chemotherapy for malignant gliomas
    • KORNBLITH, P.L., and WALKER, M. (1988). Chemotherapy for malignant gliomas. J. Neurosurg. 68, 1-17.
    • (1988) J. Neurosurg. , vol.68 , pp. 1-17
    • Kornblith, P.L.1    Walker, M.2
  • 17
    • 0028266108 scopus 로고
    • Contemporary approaches to the treatment of malignant gliomas with radiation therapy
    • LEIBEL, S.A., SCOTT, C.B., and LOEFFLER, J.S. (1994). Contemporary approaches to the treatment of malignant gliomas with radiation therapy. Semin. Oncol. 21, 198-219.
    • (1994) Semin. Oncol. , vol.21 , pp. 198-219
    • Leibel, S.A.1    Scott, C.B.2    Loeffler, J.S.3
  • 18
    • 0027407198 scopus 로고
    • In vivo gene transfer and expression in normal uninjured blood vessels using replication-deficient recombinant adenovirus vectors
    • LEMARCHAND, P., JONES, M., YAMADA, I., and CRYSTAL, R.G. (1993). In vivo gene transfer and expression in normal uninjured blood vessels using replication-deficient recombinant adenovirus vectors. Circulation Res. 72, 1132-1138.
    • (1993) Circulation Res. , vol.72 , pp. 1132-1138
    • Lemarchand, P.1    Jones, M.2    Yamada, I.3    Crystal, R.G.4
  • 19
    • 0022485359 scopus 로고
    • Tumor chemosensitivity conferred by inserted herpes thymidine kinase genes: Paradigm for a prospective cancer control strategy
    • MOOLTEN, F.L. (1986). Tumor chemosensitivity conferred by inserted herpes thymidine kinase genes: Paradigm for a prospective cancer control strategy. Cancer Res. 46, 5276-5581.
    • (1986) Cancer Res. , vol.46 , pp. 5276-5581
    • Moolten, F.L.1
  • 20
    • 0025444099 scopus 로고
    • Lymphoma regression induced by ganciclovir in mice bearing a herpes thymidine kinase transgene
    • MOOLTEN, F.L., WELLS, J.M., HEYMAN, R.A., and EVANS, R.M. (1990). Lymphoma regression induced by ganciclovir in mice bearing a herpes thymidine kinase transgene. Hum. Gene Ther. 1, 125-134.
    • (1990) Hum. Gene Ther. , vol.1 , pp. 125-134
    • Moolten, F.L.1    Wells, J.M.2    Heyman, R.A.3    Evans, R.M.4
  • 22
    • 0021281914 scopus 로고
    • A new animal model for human respiratory tract disease due to adenovirus
    • PACINI, D.L., DUBOVI, E.J., and WALLACE, A.C., JR. (1984). A new animal model for human respiratory tract disease due to adenovirus. J. Infect. Dis. 150, 92-97.
    • (1984) J. Infect. Dis. , vol.150 , pp. 92-97
    • Pacini, D.L.1    Dubovi, E.J.2    Wallace Jr., A.C.3
  • 24
    • 0027317796 scopus 로고
    • Toxicity studies of retroviral-mediated gene transfer for the treatment of brain tumors
    • RAM, Z., CULVER, K.W., WALBRIDGE, S., FRANK, J.A., BLAESE, R.M., and OLDFIELD, E.H. (1993). Toxicity studies of retroviral-mediated gene transfer for the treatment of brain tumors. J. Neurosurg. 79, 400-407.
    • (1993) J. Neurosurg. , vol.79 , pp. 400-407
    • Ram, Z.1    Culver, K.W.2    Walbridge, S.3    Frank, J.A.4    Blaese, R.M.5    Oldfield, E.H.6
  • 27
    • 0021049622 scopus 로고
    • Interstitial microwave hyperthermia for brain tumors. Results of a phase-1 clinical trial
    • SALCMAN, M., and SAMARAS, G.M. (1983). Interstitial microwave hyperthermia for brain tumors. Results of a phase-1 clinical trial. J. Neurooncol. 1, 225-236.
    • (1983) J. Neurooncol. , vol.1 , pp. 225-236
    • Salcman, M.1    Samaras, G.M.2
  • 28
  • 30
    • 0028348372 scopus 로고
    • Use of recombinant adenovirus to transfer the herpes simplex virus thymidine kinase (HSVtk) gene to thoracic neoplasms: An effective in vitro drug sensitization system
    • SMYTHE, W.R., HWANG, H.C., AMIN, K.M., ECK, S.L., DAVIDSON, B.L., WILSON, J.M., KAISER, L.R., and ALBELDA, S.M. (1994). Use of recombinant adenovirus to transfer the herpes simplex virus thymidine kinase (HSVtk) gene to thoracic neoplasms: an effective in vitro drug sensitization system. Cancer Res. 54, 2055-2059.
    • (1994) Cancer Res. , vol.54 , pp. 2055-2059
    • Smythe, W.R.1    Hwang, H.C.2    Amin, K.M.3    Eck, S.L.4    Davidson, B.L.5    Wilson, J.M.6    Kaiser, L.R.7    Albelda, S.M.8
  • 34
    • 0031034030 scopus 로고    scopus 로고
    • Innate immune mechanisms dominate elimination of adenoviral vectors following in vivo administration
    • WORGALL, S., WOLFF, G., FALCK-PEDERSEN, E., and CRYSTAL, R.G. (1997). Innate immune mechanisms dominate elimination of adenoviral vectors following in vivo administration. Hum. Gene Ther. 8, 37-44.
    • (1997) Hum. Gene Ther. , vol.8 , pp. 37-44
    • Worgall, S.1    Wolff, G.2    Falck-Pedersen, E.3    Crystal, R.G.4
  • 35
    • 0028937785 scopus 로고
    • Cellular and humoral immune responses to viral antigens create barriers to lung-directed gene therapy with recombinant adenoviruses
    • YANG, Y., LI, Q., ERTL, H.C., and WILSON, J.M. (1995). Cellular and humoral immune responses to viral antigens create barriers to lung-directed gene therapy with recombinant adenoviruses. J. Virol. 69, 2004-2015.
    • (1995) J. Virol. , vol.69 , pp. 2004-2015
    • Yang, Y.1    Li, Q.2    Ertl, H.C.3    Wilson, J.M.4
  • 36
    • 0027984919 scopus 로고
    • In vivo evaluation of the safety of adenovirus-mediated transfer of the human cystic fibrosis trans-membrane conductance regulator cDNA to the lung
    • YEI, S., MITTEREDER, N., WERT, S., WHITSETT, J.A., WILMOTT, R.W., and TRAPNELL, B.C. (1994). In vivo evaluation of the safety of adenovirus-mediated transfer of the human cystic fibrosis trans-membrane conductance regulator cDNA to the lung. Hum. Gene Ther. 5, 731-744.
    • (1994) Hum. Gene Ther. , vol.5 , pp. 731-744
    • Yei, S.1    Mittereder, N.2    Wert, S.3    Whitsett, J.A.4    Wilmott, R.W.5    Trapnell, B.C.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.