Induction of apoptosis and apoptotic mediators in Balb/C splenic lymphocytes by dietary n-3 and n-6 fatty acids

Lipids

Volumn 34, Issue 9, 1999, Pages 921-927

  Avula, C P Reddy ^a   Zaman, A K ^a   Lawrence, R ^a   Fernandes, G ^a,b  

^a UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT SAN ANTONIO   (United States)

^b UNIVERSITY OF TEXAS AT SAN ANTONIO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA TOCOPHEROL; CD3 ANTIGEN; CORN OIL; FAS ANTIGEN; FAS LIGAND; FISH OIL; LIPID PEROXIDE; LIPOCORTIN 5; MONOCLONAL ANTIBODY; OMEGA 3 FATTY ACID; OMEGA 6 FATTY ACID; POLYUNSATURATED FATTY ACID; PROPIDIUM IODIDE; PROTEIN BCL 2;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CONTROLLED STUDY; FAT INTAKE; FEMALE; LIPID COMPOSITION; LYMPHOCYTE PROLIFERATION; MEDIATOR; MOUSE; NONHUMAN; SPLEEN LYMPHOCYTE;

ANIMALS; ANTIGENS, CD95; APOPTOSIS; CELL DIVISION; CORN OIL; DIETARY FATS, UNSATURATED; FAS LIGAND PROTEIN; FATTY ACIDS, OMEGA-3; FATTY ACIDS, OMEGA-6; FATTY ACIDS, UNSATURATED; FEMALE; FISH OILS; LIPID PEROXIDES; LYMPHOCYTES; MEMBRANE GLYCOPROTEINS; MICE; MICE, INBRED BALB C; PROTO-ONCOGENE PROTEINS C-BCL-2; SPLEEN; WEANING;

ANIMALIA; ZEA MAYS;

EID: 0032740864     PISSN: 00244201     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11745-999-0441-1     Document Type: Article

References (66)

1. Fernandas, G., and Venkatraman, J.T. (1993) Role of Omega-3 Fatty Acids in Health and Disease, Nutr. Res. 13, S19-S45.
2. Calder, P.C. (1997) n-3 Polyunsaturated Fatty Acids and Cytokine Production in Health and Disease, Ann. Nutr. Metab. 41, 203-234.
3. Reddy, B.S. (1994) Chemoprevention of Colon Cancer by Dietary Fatty Acids, Cancer Metastasis Rev. 13, 285-302.
4. Narisawa, T., Fukaura, Y., Yazawa, K., Ishikawa C., and Nishizava, Y. (1994) Colon Cancer Prevention with a Small Amount of Dietary Perilla Oil High in Alpha-Linolenic Acid in an Animal Model, Cancer 73, 2069-2075.
5. Fernandes, G. (1989) Effects of Dietary Fish Oil Supplement on Autoimmune Disease: Changes in Lymphoid Cell Subsets, Oncogene mRNA Expression and Neuroendocrine Hormones, in Health Effects of Fish and Fish Oils (Chandra, R., ed.), Vol. 66, pp. 488-503, ARTS Biomed Press, St. Johns, Newfoundland.
6. Venkatraman, J.T., Chandrasekar, B., Kim, J.D., and Fernandes, G. (1994) Effects of n-3 Fatty Acids on Activities and Expression of Hepatic Antioxidant Enzymes in Autoimmune-Prone NZB/NZWf1 Mice, Lipids 29, 561-568.
7. Fernandes, G. (1994) Dietary Lipids and Risk of Autoimmune Disease, J. Clin. Immunol. Immunopathol. 72, 193-197.
8. Fernandes, G., Chandrasekar, B., Venkatraman, J., Tomar, V., and Zhao, W. (1994) Increased TGF b and Decreased Oncogene Expression by ω-3 Lipids in the Spleen Delays Autoimmune Disease in B/W Mice, J. Immunol. 152, 5979-5987.
9. Chandrasekar, B., Troyer, D. A., Venkatraman, J.T., and Fernandes, G. (1995) Dietary Omega-3 Lipids Delay the Onset and Progression of Autoimmune Lupus Nephritis by Inhibiting Transforming Growth Factor-beta mRNA and Protein Expression, J. Autoimmun. 8, 381-393.
10. Rose, D.P., Connolly, J.M., Rayburn, J., and Coleman, M. (1995) Influence of Diets Containing Eicosapentaenoic or Docosahexaenoic Acid on Growth and Metastasis of Breast Cancer Cells in Nude Mice, J. Natl. Cancer Inst. 87, 587-592.
11. Fernandes, G., and Venkatraman, J.T. (1991) Modulation of Breast Cancer Growth in Nude Mice by Omega-3 Lipids, in Health Effects of ω3 Polyunsaturated Fatty Acids in Seafoods, (Simopoulos, A.P., Kifer, R.R., Martin, R.E., and Barlow, S.M., eds.) World Rev. Nutr. Diet, Vol. 66, pp. 488-503, Karger, Basel.
12. Calder, P.C., Davis, J., Yaqoob, P., Pala, H., Thies, F., and Newsholme, E.A. (1998) Dietary Fish Oil Suppresses Human Colon Tumor Growth in Athymic Mice, Clin. Sci. 94, 303-311.
13. Tang, D.G., Guan, K.L., Li, L., Honn, K.V., Chen, Y.Q., Rice, R.L., Taylor, J.D., and Porter, A.T. (1997) Suppression of W256 Carcinosarcoma Cell Apoptosis by Arachidonic Acid and Other Polyunsaturated Fatty Acids, Int. J. Cancer 72, 1078-1087.
14. Southgate, J., Pitt, E., and Trejdosiewicz, L.K. (1996) The Effects of Dietary Fatty Acids on the Proliferation of Normal Human Urothelial Cells in vitro, Br. J. Cancer 74, 728-734.
15. Garrido, A., Garrido, F., Guerra, R., and Valenzuela, A. (1989) Ingestion of High Doses of Fish Oil Increases the Susceptibility of Cellular Membranes to the Induction of Oxidative Stress, Lipids 24, 833-835.
16. Reddy, P., and Lokesh, B. (1994) Dietary Unsaturated Fatty Acids, Vitamin E, Curcumin and Eugenol Alter Serum and Liver Lipid Peroxidation in Rats, Nutr. Res. 14, 1423-1437.
17. L'Abbe, M. R., Trick K. D., and Beare-Rogers, J.L. (1991) Dietary (n-3) Fatty Acids Effect on Rat Heart, Liver, and Aorta Protective Enzyme Activities and Lipid Peroxidation, J. Nutr. 121, 1331-1340.
18. Hawkins, R.A., Sangster, K., and Arends, M.J. (1998) Apoptotic Death of Pancreatic Cancer Cells Induced by Polyunsaturated Fatty Acids Varies with Double Bond Number and Involves an Oxidative Mechanism, J. Pathol. 185, 61-70.
19. Forrest, V.J., Kang, Y.H., McClain, D.E., Robinson, D.H., and Ramakrishnan, N. (1994) Oxidative Stress-Induced Apoptosis Prevented by Trolox, Free Radical Biol. Med. 16, 675-684.
20. Favier, A., Sappey, C., LeClerc, P., Faure, P., and Micoud, M. (1994) Antioxidant Status and Lipid Peroxidation in Patients Infected with HIV, Chem. Biol. Interact. 91, 165-180.
21. Buttke, T.M., and Sandstrom, P.A. (1994) Oxidative Stress as a Mediator of Apoptosis, Immunol. Today 15, 7-10.
22. Cohen, J. J. (1996) Apoptosis and Its Regulation, Adv. Exp. Med. Biol. 406, 11-20.
23. Wyllie, A.H., Kerr, J.F., and Currie, A.R. (1980) Cell Death: The Significance of Apoptosis, Int. Rev. Cytol. 68, 251-306.
24. Osborne, B.A. (1996) Apoptosis and the Maintenance of Homeostasis in the Immune System, Curr. Opin. Immunol. 8, 245-254.
25. Williams, G., and Smith, C. (1993) Molecular Regulation of Apoptosis: Genetic Controls on Cell Death, Cell 74, 777-779.
26. Linette, G.P., and Korsmeyer, S. (1994) Differentiation and Cell Death: Lessons from the Immune System, Cur. Opin. Cell Biol 6, 809-815.
27. Mountz, J.D., Zhou, T., Wu, J., Wang, W., Su, X., and Cheng, J. (1995) Regulation of Apoptosis in Immune Cells, J. Clin. Immunol. 15, 1-16.
28. Oehm, A., Behrmann, I., Falk, W., Pawlita, M., Maier, G., Klas, C., Li-Weber, M., Richards, S., Dheim, J., Trauth, B.C., Ponsting, H., and Krammer, P.H. (1992) Purification and Molecular Cloning of the Apo-1 Cell Surface Antigen, a Member of the Tumor Necrosis Factor/Nerve Growth Factor Receptor Superfamily, J. Biol. Chem. 267, 10709-10715.
29. Matiba, B., Mariani, S.M., and Krammer, P.H. (1997) The CD95 System and the Death of a Lymphocyte, Semin. Immunol. 9, 59-68.
30. Suda, T., Takahashi, T., Golstein, P., and Nagata, S. (1993) Molecular Cloning and Expression of the Fas Ligand, a Novel Member of the Tumor Necrosis Factor Family, Cell 75, 1169-1178.
31. Suda, T., Okazaki, T., Naito, Y., Yokota, T., Arai, N., Ozaki, S., Nakao, K., and Nagata, S. (1995) Expression of the Fas Ligand in Cells of T Cell Lineage, J. Immunol. 154, 3806-3813.
32. Schneider, P., Thome, M., Burns, K., Bodmer, J.L., Hofmann, K., Kataoka, T., Holler, N., and Tschopp, J. (1997) TRAIL Receptors 1 (DR4) and 2 (DR5) Signal FADD-Dependent Apoptosis and Activate NF-kappaB, Immunity 7, 831-836.
33. Brunner, T., Mogil, R.J., LaFace, D., Yoo, N.J., Mahboubi, A., Echeverri, F., Martin, S.J., Force, W.R., Lynch, D.H., Ware, C.F., et al. (1995) Cell-Autonomous Fas (CD95)/Fas-Ligand Interaction Mediates Activation-Induced Apoptosis in T-Cell Hybridomas, Nature 373, 441-444.
34. Ju, S.T., Panka, D.J., Cui, H., Ettinger, R., el-Khatib, M., Sherr, D.H., Stanger, B.Z., and Marshak-Rothstein, A. (1995) Fas(CD95)/FasL Interactions Required for Programmed Cell Death After T-Cell Activation, Nature 373, 444-448.
35. Boise, L.H., Gonzalez-Garcia, M., Postema, C.E., Ding, L., Lindsten, T., Turka, L., Mao, X., Nunez, G., and Thompson, C.B. (1993) Bcl-x, a Bcl-2 Related Gene That Functions as a Dominant Regulator of Apoptotic Cell Death, Cell 74, 597-608.
36. Avula, C.P., and Fernandes, G. (1999) Modulation of Antioxidant Enzymes and Apoptosis in Mice by Dietary Lipids and Treadmill Exercise [In Process Citation], J. Clin. Immunol. 19, 35-44.
37. American Institute of Nutrition (1977) Report of the American Institute of Nutrition Ad Hoc Committee on Standards for Nutritional Studies, J. Nutr. 107, 1340-1348.
38. Rushing, G.L., Cooper, W.M., and Thompson, H.C.J. (1991) Simultaneous Analysis of Vitamin A and E in Rodent Feed by High-Pressure Liquid Chromatography, J. Agric. Food Chem. 39, 296-299.
39. Hockenbery, D.M., Oltvai, Z.N., Yin, X.M., Milliman, C.L., and Korsmeyer, S.J. (1993) Bcl-2 Functions in an Antioxidant Pathway to Prevent Apoptosis, Cell 75, 241-251.
40. Darzynkiewicz, Z., Bruno, S., Del Bino, G., Gorzyca, W., Holz, M.A., Lassota, P., and Traganos, F. (1992) Features of Apoptotic Cells Measured by Flow Cytometry, Cytometry 13, 795-808.
41. Bass, D.A., Parce, J.W., Dechatelet, L.R., Szejda, P., Seeds, M.C., and Thomas, M. (1983) Flow Cytometric Studies of Oxidative Product Formation by Neutrophils: A Graded Response to Membrane Stimulation, J. Immunol. 130, 1910-1917.
42. Homburg, C.H., de Haas, M., von dem Borne, A.E., Verhoeven, A.J., Reutelingsperger, C.P., and Roos, D. (1995) Human Neutrophils Lose Their Surface Fc Gamma RIII and Acquire Annexin V Binding Sites During Apoptosis in vitro, Blood 85, 532-540.
43. Koopman, B., Reutelingsperger, C.P., Kuijiten, G.A., Kechnen, R.M., Pals, S.T., and van Oers, M.H. (1994) Annexin V for Flow Cytometric Detection of Phosphatidylserine Expression on B Cells Undergoing Apoptosis, Blood 84, 1415-1420.
44. Meydani, S.N., Endres, S., Woods, M.M., Goldin, B.R., Soo, C., Morrill-Labrode, A., Dinarello, C.A., and Gorbach, S.L. (1991) Oral (n-3) Fatty Acid Supplementation Suppresses Cytokine Production and Lymphocyte Proliferation: Comparison Between Young and Older Women, J. Nutr. 121, 547-555.
45. Allard, J.P., Kurian R., Aghdass, E., Muggli, R., and Royall, D. (1997) Lipid Peroxidation During n-3 Fatty Acid and Vitamin E Supplementation in Humans, Lipids 32, 535-541.
46. Fernandes, G., Chandrasekar, B., Luan, X., and Troyer, D. (1996) Modulation of Antioxidant Enzymes and Programmed Cell Death by n-3 Fatty Acids, Lipids 31, S91-S96.
47. Calviello, G., Palozza, P., Piccioni, E., Maggiano, N., Frattucci, A., Franceschelli, P., and Bartoli, G.M. (1998) Dietary Supplementation with Eicosapentaenoic Acid and Docosahexaenoic Acid Inhibits Growth of Marris Hepatocarcinoma 3924 A in Rats. Effects on Proliferation and Apoptosis, Int. J. Cancer 75, 699-705.
48. Gonzalez, M., Schemmel, R., Dugan, L., Gray, J., and Welsch, C. (1993) Dietary Fish Oil Inhibits Human Breast Carcinoma Growth: A Function of Increased Lipid Peroxidation, Lipids 28, 827-832.
49. Chajes, V., Sattler, W., Stranzl, A., and Kostner, G.M. (1995) Influence of n-3 Fatty Acids on the Growth of Human Breast Cancer Cells in vitro: Relationship to Peroxides and Vitamin E, Breast Cancer Res. Treat. 34, 199-212.
50. Gonzalez, M.J., Schemmel, R.A., Gray, J.I., Dugan, L., Sheffield, G., and Welsch, C.W. (1991) Effect of Dietary Fat on Growth of MCF-7 and MDA 231 Human Breast Carcinomas in Athymic Nude Mice: Relationship Between Carcinoma Growth and Lipid Peroxidation Product Levels, Carcinogenesis 12, 1231-1235.
51. Nagata, S., and Golstein, P. (1995) The Fas Death Factor, Science 267, 1449-1456.
52. Kabelitz, D., Pohl, T., and Pechhold, K. (1993) Activation-Induced Cell Death (apoptosis) of Mature Peripheral T Lymphocytes, Immunol. Today 14, 338-339.
53. Green, D.R., and Scott, D.W. (1994) Activation-Induced Apoptosis in Lymphocytes, Curr. Opin. Immunol. 6, 476-487.
54. Mountz, J.D., Zhou, T., Su, X., Wu, J., and Cheng, J. (1996) The Role of Programmed Cell Death as an Emerging New Concept for the Pathogenesis of Autoimmune Diseases, Clin. Immunol. Immunopathol. 80, S2-S14.
55. Kovacs, B., Vassilopoulos, D., Vogelgesang, S.A., and Tsokos, G.C. (1996) Defective CD3-Mediated Cell Death in Activated T Cells from Patients with Systemic Lupus Erythematosus: Role of Decreased Intracellular TNF-Alpha, Clin. Immunol. Immunopathol. 81, 293-302.
56. Strand, S., Hofmann, W.J., Hug, H., Muller, M., Otto, G., Strand, D., Mariani, S.M., Stremmel, W., Krammer, P.H., and Galle, P.R. (1996) Lymphocyte Apoptosis Induced by CD95 (APO-1/Fas) Ligand-Expressing Tumor Cells - a Mechanism of Immune Evasion? Nat. Med. 2, 1361-1366.
57. Hueber, A.O., Zornig, M., Lyon, D., Suda, T., Nagata, S., and Evan, G.I. (1997) Requirement for the CD95 Receptor-Ligand Pathway in c-Myc-Induced Apoptosis, Science 278, 1305-1309.
58. Klas, C., Debatin, K.M., Jonker, R.R., and Krammer, P.H. (1993) Activation Interferes with the APO-1 Pathway in Mature Human T Cells, Int. Immunol. 5, 625-630.
59. Reed, J.C. (1997) Double Identity for Proteins of the Bcl-2 Family, Nature 387, 773-776.
60. Kane, D.J., Sarafian, T.A., Anton, R., Hahn, H., Gralla, E.B., Balentine, J.S., Ord, T., and Bredesen, D.E. (1993) Bcl-2 Inhibition of Neural Death: Decreased Generation of Reactive Oxygen Species, Science 262, 1274-1277.
61. Hotchkiss, R.S., Swanson, P.E., Knudson, C.M., Chang, K.C., Cobb, J.P., Osborne, D.F., Zollner, K.M., Buchman, T.G., Korsmeyer, S.J., and Karl, I.E. (1999) Over Expression of Bcl-2 in Transgenic Mice Decreases Apoptosis and Improves Survival in Sepsis, J. Immunol. 162, 4148-4156.
62. White, C.A., McCombe, P.A., and Pender, M.P. (1998) The Roles of Fas, Fas Ligand and Bcl-2 in T cell Apoptosis in the Central Nervous System in Experimental Autoimmune Encephalomyelitis, J. Neuroimmunol. 82, 47-55.
63. Cohen, S.M. (1998) Cell Proliferation and Carcinogenesis, Drug Metab. 30, 339-357.
64. Jolly, C.A., Jiang, Y.H., Chapkin, R.S., and Mcmurry, D.N. (1997) Dietary (n-3) Polyunsaturated Fatty Acids Suppress Murine Lymphoproliferation, Interleukin-2 Secretion, and the Formation of Diacylglycerol and Ceramide, J Nutr. 127, 37-43.
65. Endres, S., Meydani, S.N., Ghorbani, R., Schindler, R., and Dinarello, C.A. (1993) Dietary Supplementation with n-3 Fatty Acids Suppresses Interleukin-2 Production and Mononuclear Cell Proliferation, J. Leukocyte Biol. 54, 599-603.
66. Kelley, D.S., Taylor, P.C., Nelson, G.J., Schmidt, P.C., Ferretti, A., Erickson, K.L., Yu, R., Chandra, R.K., and Mackey, B.E. (1999) Docosahexaenoic Acid Ingestion Inhibits Natural Killer Cell Activity and Production of Inflammatory Mediators in Young Healthy Men, Lipids 34, 317-324.