Presence of CpG DNA and the local cytokine milieu determine the efficacy of suppressive DNA vaccination in experimental autoimmune encephalomyelitis

Journal of Immunology

Volumn 163, Issue 9, 1999, Pages 4754-4762

  Lobell, Anna ^a   Weissert, Robert ^b   Eltayeb, Sana ^b   Svanholm, Cecilia ^a   Olsson, Tomas ^b   Wigzell, Hans ^a  

^a KAROLINSKA INSTITUTE   (Sweden)

^b KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEMENTARY DNA; CYTOKINE; DNA VACCINE; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR RECEPTOR; IMMUNOGLOBULIN G; INTERLEUKIN 10; INTERLEUKIN 4; MYELIN BASIC PROTEIN; TUMOR NECROSIS FACTOR ALPHA;

ALLERGIC ENCEPHALOMYELITIS; ANIMAL MODEL; ARTICLE; CLINICAL FEATURE; CONTROLLED STUDY; CPG ISLAND; CYTOKINE PRODUCTION; DNA SEQUENCE; DRUG EFFICACY; IMMUNOSTIMULATION; LYMPHOCYTE PROLIFERATION; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; T LYMPHOCYTE ACTIVATION; TREATMENT OUTCOME; VACCINATION;

ADJUVANTS, IMMUNOLOGIC; AMINO ACID SEQUENCE; ANIMALS; CPG ISLANDS; CRICETINAE; CYTOKINES; ENCEPHALOMYELITIS, AUTOIMMUNE, EXPERIMENTAL; HUMANS; IMMUNIZATION, SECONDARY; IMMUNOSUPPRESSIVE AGENTS; INJECTIONS, INTRAMUSCULAR; MALE; MOLECULAR SEQUENCE DATA; MYELIN BASIC PROTEINS; PEPTIDE FRAGMENTS; PLASMIDS; RATS; RATS, INBRED LEW; VACCINES, DNA;

EID: 0032735735     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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