Adult and neonatal anti-Gal response in knock-out mice for α1,3galactosyltransferase

Xenotransplantation

Volumn 5, Issue 3, 1998, Pages 191-196

  LaTemple, Denise C ^a   Galili, Uri ^a  

^a DREXEL UNIVERSITY COLLEGE OF MEDICINE   (United States)

Author keywords

Anti Gal; Knock out mouse; Tolerance; gal epitopes

Indexed keywords

GALACTOSYLTRANSFERASE;

ANIMAL EXPERIMENT; ANTIBODY PRODUCTION; ANTIGEN EXPRESSION; ANTIGEN RECOGNITION; ARTICLE; CONTROLLED STUDY; IMMUNIZATION; IMMUNOLOGICAL TOLERANCE; KNOCKOUT MOUSE; MOUSE; NONHUMAN; PRIORITY JOURNAL;

EID: 0031688001     PISSN: 0908665X     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1399-3089.1998.tb00027.x     Document Type: Article

References (31)

1. GALILI U. Interaction of the natural anti-Gal antibody with α-galactosyl epitopes: A major obstacle for xenotransplantation in humans. Immunol Today 1993:14:480.
2. GOOD H, COOPER DKC, MALCOLM AJK, IPPOLITO RM, KOREN E, NEETHLING FA, YE Y, ZUHDI N, LAMONTAGNE LR. Identification of carbohydrate structures which bind human anti-porcine antibodies: Implications for discordant grafting in man. Transplant Proc 1992:24:559.
3. SANDRIN M, VAUGHAN HA, DABKOWSKI PL, MCKENZIE IFC. Anti-pig IgM antibodies in human serum react predominantly with Galα1-3Gal epitopes. Proc Natl Acad. Sci USA 1993:90:11391.
4. COLLINS BH, COTTERELL AH, MCCURRY KR, ALVARADO CG, MAGEE JC, PARKER W, PLATT JL. Cardiac xenografts between primate species provide evidence of the α-galactosyl determinant in hyperacute rejection. J Immunol 1994:154:5500.
5. SCHAPHERDER AFM, DAHA MR, TEBULTE MTJW, VANDERWOUDE FJ, GOOZEN HG. Antibody-dependent cell-mediated cytotoxicity against porcine endothelium induced by a majority of human sera. Transplantation 1994:57:1376.
6. WATIER H, GUILLAUMIN J-M, VALLEE I, THIBAULT G, GRUEL Y, LEBRANCHU Y, BARDOS P. Human NK cell-mediated direct and IgG dependent cytotoxicity against xenogeneic porcine endothelial cells. Transplant Immunol 1996:4:293.
7. 3 are not required for fertilization in the mouse. J Biol Chem 1995:270:21437.
8. TEARLE RG, TANGE MJ, ZANNETTINO ZL, KATERELOS M, SHINKEL TA, VANDENDEREN BJ, LONIE AJ, LYONS I, NOTTLE MB, COX T, BECKER C, PEURA AM, WIGLEY PL, CRAWFORD RJ, ROBINS AJ, PEARSE MJ, D'APICE AJ. The α1,3-galactosyltransferase knockout mouse: Implications for xenotransplantation. Transplantation 1996:61:13.
9. THALL AD, MURPHY HS, LOWE JB. α1,3-galactosyltransferase-deficient mice produce naturaly occurring cytotoxic anti-Gal antibodies. Transplant Proc 1996:28:556.
10. LAW LW, HENRIKSEN O. Induction of neonatal tolerance to the male-specific (H-Y) antigens by membrane and solubilized preparations of spleen cells. Transplantation 1978:26:359.
11. RIDGE JP, FUCHS FJ, MATZINGER P. Neonatal tolerance revisited: Turning on newborn T cells with dendritic cells. Science 1996:271:1723.
12. THALL A, GALILI U. The differential expression of Galα1-3Galβ1-4GlcNAc-R residues on mammalian secreted N-glycosylated glycoproteins. Biochemistry 1990:29:3959.
13. GALILI U, LATEMPLE DC, WALGENBACH AW, STONE KR. Porcine and bovine cartilage transplants in cynomolgus monkey. II. Changes in anti-Gal response during chronic rejection. Transplantation 1997:63:646.
14. GALILI U, SHOHET SB, KOBRIN E, STULTS CLM, MACHER BA. Man, apes, and Old World monkeys differ from other mammals in the expression of α-galactosyl epitopes on nucleated cells. J Biol Chem 1988:263:17755.
15. ARUMUGHAM RG, HSIEH TCY, TANZER ML, LAINE LA. Structure of the aspargine-linked sugar chains of laminin. Biochem. Biophys. Acta 1986:883:112.
16. SHIBATA S, PETERS BP, ROBERTS DD, GOLDSTEIN TJ, LIOTTA LA. Isolation of laminin by affinity chromatography on immobilized Griffonia simplicifolia I lectin. FEBS Lett 1982:142:194.
17. GALILI U. Evolution and pathophysiology of the human natural anti-Gal antibody. Springer Sem Immunopathol 1993:15:155.
18. SPIRO RG, BHOYROO VD. Occurence of α-D-galactosyl residues in the thyroglobulins of several species: Localization in the saccharide chain of the complex carbohydrate unit. J Biol Chem 1984:259:9858.
19. GALILI U, RACHMILEWITZ EA, PELEG A, FLECHNER I. A unique natural human IgG antibody with anti-α-galactosyl specificity. J Exp Med 1984:160:1519.
20. ETO T, IICHIKAWA Y, NISHIMURA K, ANDO S, YAMAKAWA T. Chemistry of lipids of the posthemolytic residue or stroma of erythrocytes. XVI. Occurrence of ceramide pentasaccharide in the membrane of erythrocytes and reticulocytes in rabbit. J Biochem 1968:64:205.
21. STELLNER K, SAITO H, HAKOMORI SI. Determination of aminosugar linkage in glycolipids by methylation. Aminosugar linkage of ceramide pentasaccharides of rabbit erythrocytes and of Forssman antigen. Arch Biochem Biophys 1973:155:464.
22. EGGE H, KORDOWICZ M, PETER-KATALINIC J, HANFLAND P. Immunochemistry of I/i-active oligo- and polyglycosylceramides from rabbit erythrocyte membranes. J Biol Chem 1985:260:4927.
23. GALILI U, CLARK MR, SHOHET SB, BUEHLER J, MACHER BA. Evolutionary relationship between the anti-Gal antibody and the Galα1,3Gal epitope in primates. Proc Natl Acad Sci USA 1987:84:1369.
24. BILLINGHAM RE, BRENT L, MEDAWAR PB. Actively acquired tolerance of foreign cells. Nature 1953:172:603.
25. ZORZOTTI M, ROBBINS DS, HOFFMAN PM. Induction of protective CTL responses in newborn mice by a murine retrovirus. Science 1996:271:1726.
26. PIROFSKY B, CORDOVA M, ACNAYO A, SEN TIES LM. Production of immune tolerance in humans. Nature 1968: 218:284.
27. OWEN RD. Immunogenetic consequences of vascular anastomoses between bovine twins. Science 1945:102:400.
28. NEMAZEE DA, BURKI K. Clonal deletion of B lymphocytes in a transgenic mouse bearing anti-MHC class I antibody genes. Nature 1989:337:562.
29. HARTLEY SB, CROSBIE J, BRINK R, KANTOR AB, BASTEN A, GOODNOW CC. Elimination from peripheral lymphoid tissues of self-reactive B lymphocytes recognizing membrane bound antigens. Nature 1991:353:765.
30. 2 immunity in neonatal mice. Science 1996:271:17.
31. FIELD EH, GAO Q, CHEN N, ROUSE TM. Balancing the immune system for tolerance. Transplantation 1997:64:1.