Induction of specific transplantation tolerance across xenogeneic barriers in the T-independent immune compartment

Nature Medicine

Volumn 4, Issue 2, 1998, Pages 173-180

  Lin, Yuan ^a   Goebels, Jozef ^a   Xia, Guliang ^a   Ji, Ping ^a   Vandeputte, Michel ^b   Waer, Mark ^a  

^a UNIVERSITY OF LEUVEN   (Belgium)

^b REGA INSTITUTE FOR MEDICAL RESEARCH   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

LEFLUNOMIDE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; B LYMPHOCYTE; CONTROLLED STUDY; GRAFT SURVIVAL; HEART GRAFT; IMMUNOHISTOCHEMISTRY; IMMUNOLOGICAL TOLERANCE; MALE; MOUSE; NATURAL KILLER CELL; NONHUMAN; NUDE MOUSE; PRIORITY JOURNAL; SPECIES DIFFERENCE; SYRIAN HAMSTER; T LYMPHOCYTE ACTIVATION; XENOGRAFT;

ANIMALS; ANTIBODY FORMATION; ANTIGENS; COMPLEMENT ACTIVATION; CRICETINAE; CYTOKINES; GRAFT REJECTION; GRAFT SURVIVAL; HEART; HEART TRANSPLANTATION; IMMUNOGLOBULIN M; IMMUNOHISTOCHEMISTRY; IMMUNOSUPPRESSIVE AGENTS; ISOXAZOLES; KILLER CELLS, NATURAL; MACROPHAGES; MALE; MICE; MICE, INBRED C57BL; RATS; RATS, NUDE; T-LYMPHOCYTES; TRANSPLANTATION, HETEROLOGOUS;

EID: 0031906108     PISSN: 10788956     EISSN: None     Source Type: Journal    
DOI: 10.1038/nm0298-173     Document Type: Article

References (48)

1. Perper, R.J. & Najarian, J.S. Experimental renal heterotransplantation. I. In widely divergent species. Transplantation 4, 377-388 (1966).
2. Giles, G.R. et al. Mechanism and modification of rejection of heterografts between divergent species. Transplant. Proc. 2, 522-538 (1970).
3. Kakita, A., Blanchard, J. & Fortner, J.G. Hamster-to-rat cardiac xenografts: A useful model for transplantation studies. J. Surg. Res. 19, 99-106 (1975).
4. Homan, W.P., Williams, K.A., Fabre, J.W., Millad, P.R. & Morris, P.J. Prolongation of cardiac xenograft survival in rats receiving cyclosporine A. Transplantation 31, 164-166 (1981).
5. Platt, J.L. et al. The role of natural antibodies in the activation of xenogeneic endothelial cells. Transplantation 52, 1037-1043 (1991).
6. Bach, F.H. et al. Endothelial cell activation and thromboregulation during xenograft rejection. Immunol. Rev, 141, 5-30 (1994).
7. Leventhal, J.R. et al. Prolongation of cardiac xenograft survival by depletion of complement. Transplantation 55, 857-865 (1993).
8. Hancock, W.W., Blakely, M.L., van der Werf, W.J. & Bach, F.H. Rejection of guinea pig cardiac xenografts post-cobra venom factor therapy is associated with infiltration by mononuclear cells secreting IFN-γ and diffuse endothelial activation. Transplant. Proc. 25, 2932-(1993).
9. Auchincloss, H., Jr. Xenogeneic transplantation. Transplantation 46, 1-20 (1988).
10. Sachs, D.H. & Bach, F.H. Immunology of xenograft rejection. Hum. Immunol. 28, 245-251 (1990).
11. Sykes, M., Lee, LA. & Sachs, DH. Xenograft tolerance. Immunol. Rev. 141, 245-276 (1994).
12. Faustman, D. & Coe, C. Prevention of xenograft rejection by masking donor HLA class I antigens. Science 252, 1700-1702 (1991).
13. + T cells. J. Exp. Med. 170, 991-996 (1989).
14. Platt, J.L. et al. Transplantation of discordant xenografts: A review of progress. Immunol. Today 11, 450-456 (1990).
15. Bach, F.H. et al. Accommodation of vascularized xenografts: Expression of protective genes' by donor endothelial cells in a host Th2 cytokine environment. Nature Med. 3, 196-204 (1997).
16. Zhao, Y., et al. Skin graft tolerance across a discordant xenogeneic barrier. Nature Med. 2, 1211-1216 (1996).
17. Goodman, D.J., von Albertini, M., Willson, A., Millan, M.T. & Bach, F.H. Direct activation of porcine endothelial cells by human killer cells. Transplantation 61, 763-771 (1996).
18. Candinas, D. et al. T-cell independence of macrophage and NK cell infiltration, cytokine production, and endothelial activation during delayed xenograft rejection. Transplantation 62, 1920-1927 (1996).
19. Lin, Y., Vandeputte, M. & Waer, M. NK cell- and macrophage-mediated rejection of concordant xenografts in the absence of T- and B-cell responses. J. Immunol. 158, 5658-5667 (1997).
20. Roder, J.C. & Ahrlund-Richer, L. Target-effector interaction in the human and murine natural killer system: Specific and xenogeneic reactivity of the solubilized natural killer-target structure complex and its loss in a somatic cell hybrid. J. Exp. Med. 150, 471-481 (1979).
21. Roozemond, R.C., Das, P.K. & Halperin, M. Effect of mycobacterial lipids on membrane fluidity and natural killer cell-mediated cytotoxicity. Ann. Immunol. (Paris) 1350, 247-255 (1984).
22. Zinkernagel, R.M. T and B cell tolerance and responses to viral antigens in transgenic mice: Implications for the pathogenesis of autoimmune versus immunopathological disease. Immunol. Rev. 122, 133-171 (1991).
23. Sundstrom, J.B. & Cherniak, R. T-cell-dependent and T-cell-independent mechanism of tolerance to glucuronoxylomannan of Cryprococcus neoformans serotype A. Infect. Immun. 61, 1340-1345 (1993).
24. Goodnow, C.C. Transgeneic mice and analysis of B cell tolerance. Annu. Rev. Immunol. 10, 489-518 (1992).
25. Sharabi, Y., Aksentijevich, I., Sundt, T.M., III, Sachs, D.H. & Sykes, M. Specific induction of across a xenogeneic barrier: Production of mixed rat/mouse lymphohematopoietic chimeras using a nonlethal preparative regimen. J. Exp. Med. 172, 195-202 (1990).
26. Chan, E.Y. & MacLennan, I.C. Only a small proportion of splenic B cells in adults are short-lived virgin cells. Eur. J. Immunol. 23, 357-363 (1993).
27. Collins, B.H., Parker, W.R. & Platt, J.L. Characterization of porcine endothelial cell determinants recognized by human natural antibodies. Xenotransplantation 1, 36 (1994).
28. Platt, J.L., Lindman, B.J., Chen, H., Spitalnik, S.L. & Bach, F.H. Endothelial cell antigens recognized by xenoreactive human natural antibodies. Transplantation 50, 817-822 (1990).
29. Cramer, D.V., Wu, G.D., Chapman, F.A. & Makowka, L. Humoral responses to xenografts: Do concordant and discordant reactions share common immune responses? Transplant. Proc. 29, 945 (1997).
30. Gustavsson, M.L. et al. Anti-carbohydrate antibodies associated with hyperacute rejection in a vascularized mouse heart-to-rat xenotransplantation model. Transplantation 61, 957-963 (1996).
31. Schaapherder, A.F., Daha, MR., Bulte, M.T., Van der Woude, F.J. & Gooszen, H.G. Antibody-dependent cell-mediated cytotoxicity against porcine endothelium induced by a majority of human sera. Transplantation 57, 1376-1382 (1994).
32. Bach, H.F. et al. Barriers to xenotransplantation. Nature Med. 1, 869-873 (1995).
33. Roder, J.C. & Pross, H.F. The biology of human natural killer cell. J. Clin. Immunol. 2, 249-263 (1982).
34. Kiyohara, T., Dennis, J.W. & Roder, J.C. Double restriction in NK cell recognition is linked to transmethylation and can be triggered by asparagine-linked oligosaccharides on tumor cells. Cell. Immunol. 106, 223-233 (1987).
35. Rooney, C.M. & Munro, A.J. NK cells can recognize asialylated autologous lymphocytes and ABO-mismatched lymphocytes. Immunology 51, 193-199 (1984).
36. Ljunggren, H.G. & Karre, K. In search of the 'missing self': MHC molecules and NK cell recognition. Immunol. Today 11, 237-244 (1991).
37. Galili, U. Interaction of the natural anti-Gal antibody with α-galactosyl epitopes: A major obstacle for xenotransplantation in humans. Immunol Today 14, 480-482 (1993).
38. Moller, J.R. et al. Natural killer cell recognition of target cells expressing different antigens of vesicular stomatitis virus. Proc. Natl. Acad. Sci. USA 82, 2456-2459 (1985).
39. Malnati, M.S. et al. Recognition of virus-infected cells by natural killer cell clones is controlled by polymorphic target cell elements. J. Exp. Med. 178, 961-969 (1993).
40. Wu, M.F. & Raulet, D.H. Class-I-deficient hemopoietic cells and non hemopoietic cells dominantly induce unresponsiveness of natural killer cells to class-I deficient bone marrow cell grafts. J. Immunol. 158, 1628-1633 (1997).
41. Umesue, M. et al. Donor-specific prolongation of rat skin graft survival induced by rat-donor cells and cyclophosphamide under co-administration of monoclonal antibodies against T cell receptor alpha beta and natural killer cells in mice. Transplantation 61, 116-124 (1996).
42. Sykes, M. et al. Hematopoietic cells and radioresistant host elements influence natural killer cell differentiation. J. Exp. Med. 178, 223-229 (1993).
43. Silva, HT., Jr. & Morris, R.E. Leflunomide and malononitriloamide. Med. Sci. 313, 289-301 (1997).
44. Reynolds, C.W., Timonen, T. & Herberman, R.B. Natural killer cell activity in the rat. I. Isolation and characterization of the effector cells. J. Immunol. 127, 282-287 (1981).
45. Salam, A. & Waer, M. Craft-versus-host reactivity and graft-versus-leukemia effect in murine allogeneic bone marrow chimeras conditioned with total body irradiation or total lymphoid irradiation. Transplantation 61, 826-830 (1996).
46. Kabat, E.A. & Mayer, M.M. Measurement of total haemolytic complement activity. in Experimental Immunochemistry, 2nd edn., p. 149 (Charles C Thomas, Springfield, IL, 1961).
47. Coligan, J.E., Kruisbeek, A.M., Marguilies, D.H., Shevach, E.M. & Strober, W. Double antibody-sandwich ELISA to detect specific antibodies. in Current Protocols in Immunology, (eds. Coligan, J.E. et al.) 2.1, p.11 (Wiley & Sons, New York, 1994).
48. Baker, P.J. Depletion of C6 prevents development of proteinuria in experimental membranous nephropathy in rats. Am. J. Pathol. 135, 185-194 (1989).