-
1
-
-
0028878938
-
Problems of delivery of monoclonal antibodies. Pharmaceutical and pharmacokinetic solutions
-
Reilly, R. M., Sandhu, J., Alvarez-Diez, T. M., Gallinger, S., Kirsh, J., and Stern, H. Problems of delivery of monoclonal antibodies. Pharmaceutical and pharmacokinetic solutions. Clin. Pharmacokinet., 28: 126-142, 1995.
-
(1995)
Clin. Pharmacokinet.
, vol.28
, pp. 126-142
-
-
Reilly, R.M.1
Sandhu, J.2
Alvarez-Diez, T.M.3
Gallinger, S.4
Kirsh, J.5
Stern, H.6
-
2
-
-
0005866570
-
Treatment of B-cell malignancies in patients using fractionated dose (FD) or maximum tolerated dose (MTD) of I-131 Lym-1 without and with immunophoresis
-
DeNardo, G. L., DeNardo, S. J., Lewis, J. P., Mills, S. L., O'Grady, L. F., Levy, N. B., and Maddock, S. W. Treatment of B-cell malignancies in patients using fractionated dose (FD) or maximum tolerated dose (MTD) of I-131 Lym-1 without and with immunophoresis. J. Nucl. Med., 32: 921-922, 1991.
-
(1991)
J. Nucl. Med.
, vol.32
, pp. 921-922
-
-
DeNardo, G.L.1
DeNardo, S.J.2
Lewis, J.P.3
Mills, S.L.4
O'Grady, L.F.5
Levy, N.B.6
Maddock, S.W.7
-
3
-
-
0028040317
-
The biologic window for chimeric L6 radioimmunotherapy
-
Phila.
-
DeNardo, S. J., Mirick, G. R., Kroger, L. A., O'Grady, L. F., Erickson, K. L., Yuan, A., Lamborn, K. R., Hellstrom, I., Hellstrom, K. E., and DeNardo, G. L. The biologic window for chimeric L6 radioimmunotherapy. Cancer (Phila.), 73 (Suppl.): 1023-1032, 1994.
-
(1994)
Cancer
, vol.73
, Issue.SUPPL.
, pp. 1023-1032
-
-
DeNardo, S.J.1
Mirick, G.R.2
Kroger, L.A.3
O'Grady, L.F.4
Erickson, K.L.5
Yuan, A.6
Lamborn, K.R.7
Hellstrom, I.8
Hellstrom, K.E.9
DeNardo, G.L.10
-
4
-
-
0007704601
-
Advances in antibody technology for targeted cancer therapy
-
Chester, K. A., and Hawkins, R. E. Advances in antibody technology for targeted cancer therapy. Tumor Marker Update, 6: 187-195, 1994.
-
(1994)
Tumor Marker Update
, vol.6
, pp. 187-195
-
-
Chester, K.A.1
Hawkins, R.E.2
-
5
-
-
9344223986
-
Human antibodies with sub-nanomolar affinities isolated from a large non-immunized phage display library
-
Vaughan, T. J., William, A. J., Pritchard, K., Osbourn, J. K., Pope, A. R., Earnshaw, J. C., McCafferty, J., Hodits, R. A., Wilton, J., and Johnson, K. S. Human antibodies with sub-nanomolar affinities isolated from a large non-immunized phage display library. Nat. Biotechnol., 14: 309-314, 1996.
-
(1996)
Nat. Biotechnol.
, vol.14
, pp. 309-314
-
-
Vaughan, T.J.1
William, A.J.2
Pritchard, K.3
Osbourn, J.K.4
Pope, A.R.5
Earnshaw, J.C.6
McCafferty, J.7
Hodits, R.A.8
Wilton, J.9
Johnson, K.S.10
-
6
-
-
0028078866
-
Phage libraries for generation of clinically useful antibodies
-
Chester, K. A., Begent, R. H., Robson, L., Keep, P., Pedley, R. B., Boden, J. A., Boxer, G., Green, A., Winter, G., and Cochet, O. Phage libraries for generation of clinically useful antibodies. Lancet, 343: 455-456, 1994.
-
(1994)
Lancet
, vol.343
, pp. 455-456
-
-
Chester, K.A.1
Begent, R.H.2
Robson, L.3
Keep, P.4
Pedley, R.B.5
Boden, J.A.6
Boxer, G.7
Green, A.8
Winter, G.9
Cochet, O.10
-
7
-
-
0032697611
-
Development of a hyperimmune anti-MUC-1 scFv antibody phage display library for targeting breast cancer
-
Winthrop, M. D., DeNardo, S. J., and DeNardo, G. L. Development of a hyperimmune anti-MUC-1 scFv antibody phage display library for targeting breast cancer. Clin. Cancer Res., 5 (Suppl.): 3088s-3094s, 1999.
-
(1999)
Clin. Cancer Res.
, vol.5
, Issue.SUPPL.
-
-
Winthrop, M.D.1
DeNardo, S.J.2
DeNardo, G.L.3
-
8
-
-
0033030385
-
Phage library-derived human anti-TETA and anti-DOTA ScFv for pretargeting RIT
-
DeNardo, S. J., DeNardo, G. L., Brush, J., and Carter, P. Phage library-derived human anti-TETA and anti-DOTA ScFv for pretargeting RIT. Hybridoma, 18: 13-21, 1999.
-
(1999)
Hybridoma
, vol.18
, pp. 13-21
-
-
DeNardo, S.J.1
DeNardo, G.L.2
Brush, J.3
Carter, P.4
-
9
-
-
0031833527
-
New anti-Cu-TETA and anti-Y-DOTA monoclonal antibodies for potential use in the pre-targeted delivery of radiopharmaceuticals to tumor
-
Feng, X., Pak, R. H., Kroger, L. A., Moran, J. K., DeNardo, D. G., Meares, C. F., DeNardo, G. L., and DeNardo, S. J. New anti-Cu-TETA and anti-Y-DOTA monoclonal antibodies for potential use in the pre-targeted delivery of radiopharmaceuticals to tumor. Hybridoma, 17: 125-132, 1998.
-
(1998)
Hybridoma
, vol.17
, pp. 125-132
-
-
Feng, X.1
Pak, R.H.2
Kroger, L.A.3
Moran, J.K.4
DeNardo, D.G.5
Meares, C.F.6
DeNardo, G.L.7
DeNardo, S.J.8
-
10
-
-
0030039532
-
High level secretion of a humanized bispecific diabody from Escherichia coli
-
Zhu, Z., Zapata, G., Shalaby, R., Snedecor, B., Chen, H., and Carter, P. High level secretion of a humanized bispecific diabody from Escherichia coli. Biotechnology, 14: 192-196, 1996.
-
(1996)
Biotechnology
, vol.14
, pp. 192-196
-
-
Zhu, Z.1
Zapata, G.2
Shalaby, R.3
Snedecor, B.4
Chen, H.5
Carter, P.6
-
11
-
-
0028786757
-
Toward the production of bispecific antibody fragments for clinical applications
-
Carter, P., Ridgway, J., and Zhu, Z. Toward the production of bispecific antibody fragments for clinical applications. J. Hematother., 4: 463-470, 1995.
-
(1995)
J. Hematother.
, vol.4
, pp. 463-470
-
-
Carter, P.1
Ridgway, J.2
Zhu, Z.3
-
12
-
-
0027303686
-
Highly specific in vivo tumor targeting by monovalent and divalent forms of 741F8 anti-c-erbB-2 single-chain Fv
-
Adams, G. P., McCartney, J. E., Tai, M. S., Oppermann, H., Huston, J. S., Stafford, W. F., Bookman, M. A., Fand, I., Houston, L. L., and Weiner, L. M. Highly specific in vivo tumor targeting by monovalent and divalent forms of 741F8 anti-c-erbB-2 single-chain Fv. Cancer Res., 53: 4026-4034, 1993.
-
(1993)
Cancer Res.
, vol.53
, pp. 4026-4034
-
-
Adams, G.P.1
McCartney, J.E.2
Tai, M.S.3
Oppermann, H.4
Huston, J.S.5
Stafford, W.F.6
Bookman, M.A.7
Fand, I.8
Houston, L.L.9
Weiner, L.M.10
-
13
-
-
0031942906
-
Prolonged in vivo tumor retention of a human diabody targeting the extracellular domain of human HER2/neu
-
Adams, G. P., Schier, R., McCall, A. M., Crawford, S. M., Wolff, E. J., Weiner, M., and Marks, J. D. Prolonged in vivo tumor retention of a human diabody targeting the extracellular domain of human HER2/neu. Br. J. Cancer, 77: 1405-1412, 1998.
-
(1998)
Br. J. Cancer
, vol.77
, pp. 1405-1412
-
-
Adams, G.P.1
Schier, R.2
McCall, A.M.3
Crawford, S.M.4
Wolff, E.J.5
Weiner, M.6
Marks, J.D.7
-
14
-
-
0027197493
-
"Diabodies": Small bivalent and bispecific antibody fragments
-
Holliger, P., Prospero, T., and Winter, G. "Diabodies": small bivalent and bispecific antibody fragments. Proc. Natl. Acad. Sci. USA, 90: 6444-6448, 1993.
-
(1993)
Proc. Natl. Acad. Sci. USA
, vol.90
, pp. 6444-6448
-
-
Holliger, P.1
Prospero, T.2
Winter, G.3
-
15
-
-
0028136310
-
Multimerization behavior of single chain Fv variants for the tumor-binding antibody B72.3
-
Desplancq, D., King, D. J., Lawson, A. D. G., and Mountain, A. Multimerization behavior of single chain Fv variants for the tumor-binding antibody B72.3. Protein Eng., 7: 1027-1033, 1994.
-
(1994)
Protein Eng.
, vol.7
, pp. 1027-1033
-
-
Desplancq, D.1
King, D.J.2
Lawson, A.D.G.3
Mountain, A.4
-
16
-
-
0028074723
-
Multivalent Fvs: Characterization of single-chain Fv oligomers and preparation of a bispecific Fv
-
Whitlow, M., Filpula, D., Rollence, M. L., Feng, S. L., and Wood, J. F. Multivalent Fvs: characterization of single-chain Fv oligomers and preparation of a bispecific Fv. Protein Eng., 7: 1017-1026, 1994.
-
(1994)
Protein Eng.
, vol.7
, pp. 1017-1026
-
-
Whitlow, M.1
Filpula, D.2
Rollence, M.L.3
Feng, S.L.4
Wood, J.F.5
-
17
-
-
0023137637
-
Two new monoclonal antibodies, Lym-1 and Lym-2, reactive with human-B-lymphocytes and derived tumors, with immunodiagnostic and immunotherapeutic potential
-
Epstein, A. L., Marder, R. J., Winter, J. N., Stathopoulos, E., Chen, F. M., Parker, J. W., and Taylor, C. R. Two new monoclonal antibodies, Lym-1 and Lym-2, reactive with human-B-lymphocytes and derived tumors, with immunodiagnostic and immunotherapeutic potential. Cancer Res., 47: 830-840, 1987.
-
(1987)
Cancer Res.
, vol.47
, pp. 830-840
-
-
Epstein, A.L.1
Marder, R.J.2
Winter, J.N.3
Stathopoulos, E.4
Chen, F.M.5
Parker, J.W.6
Taylor, C.R.7
-
18
-
-
0001002121
-
The peptide way to macrocyclic bifunctional chelating agents: Synthesis of 2-(p-nitrobenzyl)-1,4,7,10-tetraazacyclododecane-N,-N′,N″, N‴-tetraacetic acid and study of its yttrium (III) complex
-
Moi, M. K., Meares, C. F., and DeNardo, S. J. The peptide way to macrocyclic bifunctional chelating agents: synthesis of 2-(p-nitrobenzyl)-1,4,7,10-tetraazacyclododecane-N,-N′,N″, N‴-tetraacetic acid and study of its yttrium (III) complex. J. Am. Chem. Soc., 110: 6266-6267, 1988.
-
(1988)
J. Am. Chem. Soc.
, vol.110
, pp. 6266-6267
-
-
Moi, M.K.1
Meares, C.F.2
DeNardo, S.J.3
-
19
-
-
0021868224
-
Copper chelates as probes of biological systems: Stable copper complexes with a macrocyclic bifunctional chelating agent
-
Moi, M. K., Meares, C. F., McCall, M. J., Cole, W. C., and DeNardo, S. J. Copper chelates as probes of biological systems: stable copper complexes with a macrocyclic bifunctional chelating agent. Anal. Biochem., 148: 249-253, 1985.
-
(1985)
Anal. Biochem.
, vol.148
, pp. 249-253
-
-
Moi, M.K.1
Meares, C.F.2
McCall, M.J.3
Cole, W.C.4
DeNardo, S.J.5
-
20
-
-
0025431034
-
Simplified method for conjugating macrocyclic bifunctional chelating agents to antibodies via 2-iminothiolane
-
McCall, M. J., Diril, H., and Meares, C. F. Simplified method for conjugating macrocyclic bifunctional chelating agents to antibodies via 2-iminothiolane. Bioconjugate Chem., 1: 222-226, 1990.
-
(1990)
Bioconjugate Chem.
, vol.1
, pp. 222-226
-
-
McCall, M.J.1
Diril, H.2
Meares, C.F.3
-
21
-
-
0028814493
-
Effect of the extent of chelate substitution on the immunoreactivity and biodistribution of 2IT-BAT-Lym-1 immunoconjugates
-
Kukis, D. L., DeNardo, G. L., DeNardo, S. J., Mirick, G. R., Miers, L. A., Greiner, D. P., and Meares, C. F. Effect of the extent of chelate substitution on the immunoreactivity and biodistribution of 2IT-BAT-Lym-1 immunoconjugates. Cancer Res., 55: 878-884, 1995.
-
(1995)
Cancer Res.
, vol.55
, pp. 878-884
-
-
Kukis, D.L.1
DeNardo, G.L.2
DeNardo, S.J.3
Mirick, G.R.4
Miers, L.A.5
Greiner, D.P.6
Meares, C.F.7
-
22
-
-
0026327378
-
Construction, binding properties, metabolism, and targeting of a single-chain Fv derived from the pancarcinoma monoclonal antibody CC49
-
Milenic, D. E., Yokota, T., Filpula, D. R., Finkelman, M. A. J., Dodd, S. W., Wood, J. F., Whitlow, M., Snoy, P., and Schlom, J. Construction, binding properties, metabolism, and targeting of a single-chain Fv derived from the pancarcinoma monoclonal antibody CC49. Cancer Res., 51: 6363-6371, 1991.
-
(1991)
Cancer Res.
, vol.51
, pp. 6363-6371
-
-
Milenic, D.E.1
Yokota, T.2
Filpula, D.R.3
Finkelman, M.A.J.4
Dodd, S.W.5
Wood, J.F.6
Whitlow, M.7
Snoy, P.8
Schlom, J.9
-
23
-
-
0025162270
-
A comparison of strategies to stabilize immunoglobulin Fv-fragments
-
Glockshuber, R., Malia, M., Pfitzinger, I., and Pluckthun, A. A comparison of strategies to stabilize immunoglobulin Fv-fragments. Biochemistry, 29: 1362-1367, 1990.
-
(1990)
Biochemistry
, vol.29
, pp. 1362-1367
-
-
Glockshuber, R.1
Malia, M.2
Pfitzinger, I.3
Pluckthun, A.4
-
24
-
-
0025046142
-
Anti-Tac (Fv)-PE40, a single chain antibody Pseudomonas fusion protein directed at interleukin 2 receptor bearing cells
-
Batra, J. K., FitzGerald, D., Gately, M., Chaudhary, V. K., and Pastan, I. Anti-Tac (Fv)-PE40, a single chain antibody Pseudomonas fusion protein directed at interleukin 2 receptor bearing cells. J. Biol. Chem., 265: 15198-15202, 1990.
-
(1990)
J. Biol. Chem.
, vol.265
, pp. 15198-15202
-
-
Batra, J.K.1
FitzGerald, D.2
Gately, M.3
Chaudhary, V.K.4
Pastan, I.5
-
25
-
-
0027529014
-
Characterization of the linker peptide of the single-chain Fv fragment of an antibody by NMR spectroscopy
-
Freund, C., Ross, A., Guth, B., Pluckthun, A., and Holak, T. Characterization of the linker peptide of the single-chain Fv fragment of an antibody by NMR spectroscopy. FEBS Lett., 320: 97-100, 1993.
-
(1993)
FEBS Lett.
, vol.320
, pp. 97-100
-
-
Freund, C.1
Ross, A.2
Guth, B.3
Pluckthun, A.4
Holak, T.5
-
26
-
-
0029851465
-
Antibody binding sites
-
Huston, J. S., Margolies, M. N., and Haber, E. Antibody binding sites. Adv. Protein Chem., 49: 329-450, 1996.
-
(1996)
Adv. Protein Chem.
, vol.49
, pp. 329-450
-
-
Huston, J.S.1
Margolies, M.N.2
Haber, E.3
-
28
-
-
0023724726
-
Electroporation in biology: Methods, applications, and instrumentation
-
Potter, H. Electroporation in biology: methods, applications, and instrumentation. Anal. Biochem., 174: 361-373, 1988.
-
(1988)
Anal. Biochem.
, vol.174
, pp. 361-373
-
-
Potter, H.1
-
29
-
-
0023634094
-
Production of single-stranded plasmid DNA
-
Vieira, J., and Messing, J. Production of single-stranded plasmid DNA. Methods Enzymol., 153: 3-11, 1987.
-
(1987)
Methods Enzymol.
, vol.153
, pp. 3-11
-
-
Vieira, J.1
Messing, J.2
-
30
-
-
0025740577
-
Multi-subunit proteins on the surface of filamentous phage: Methodologies for displaying antibody (Fab) heavy and light chains
-
Hoogenboom, H. R., Griffiths, A. D., Johnson, K. S., Chiswell, D. J., Hudson, P., and Winter, G. Multi-subunit proteins on the surface of filamentous phage: methodologies for displaying antibody (Fab) heavy and light chains. Nucleic Acids Res., 19: 4133-4137, 1991.
-
(1991)
Nucleic Acids Res.
, vol.19
, pp. 4133-4137
-
-
Hoogenboom, H.R.1
Griffiths, A.D.2
Johnson, K.S.3
Chiswell, D.J.4
Hudson, P.5
Winter, G.6
-
31
-
-
0025835310
-
Making antibody fragments using phage display libraries
-
Clackson, T., Hoogenboom, H. R., Griffiths, A. D., and Winter, G. Making antibody fragments using phage display libraries. Nature (Lond.), 352: 624-628, 1991.
-
(1991)
Nature (Lond.)
, vol.352
, pp. 624-628
-
-
Clackson, T.1
Hoogenboom, H.R.2
Griffiths, A.D.3
Winter, G.4
-
32
-
-
0027420237
-
Medical applications of single-chain antibodies
-
Huston, J. S., McCartney, J., Tai, M. S., Mottola-Hartshorn, C., Jin, D., Warren, F., Keck, P., and Oppermann, H. Medical applications of single-chain antibodies. Int. Rev. Immunol., 10: 195-217, 1993.
-
(1993)
Int. Rev. Immunol.
, vol.10
, pp. 195-217
-
-
Huston, J.S.1
McCartney, J.2
Tai, M.S.3
Mottola-Hartshorn, C.4
Jin, D.5
Warren, F.6
Keck, P.7
Oppermann, H.8
-
33
-
-
0028291823
-
Isolation of high affinity human antibodies directly from large synthetic repertoires
-
Griffiths, A. D., Williams, S. C., Hartley, O., Tomlinson, I. M., Waterhouse, P., Crosby, W. L., Kontermann, R. E., Jones, P. T., Low, N. M., and Allison, T. J. Isolation of high affinity human antibodies directly from large synthetic repertoires. EMBO J., 13: 3245-3260, 1994.
-
(1994)
EMBO J.
, vol.13
, pp. 3245-3260
-
-
Griffiths, A.D.1
Williams, S.C.2
Hartley, O.3
Tomlinson, I.M.4
Waterhouse, P.5
Crosby, W.L.6
Kontermann, R.E.7
Jones, P.T.8
Low, N.M.9
Allison, T.J.10
-
34
-
-
0026317443
-
By-passing immunization. Human antibodies from V-gene libraries displayed on phage
-
Marks, J. D., Hoogenboom, H. R., Bonnert, T. P., McCafferty, J., Griffiths, A. D., and Winter, G. By-passing immunization. Human antibodies from V-gene libraries displayed on phage. J. Mol. Biol., 222: 581-597, 1991.
-
(1991)
J. Mol. Biol.
, vol.222
, pp. 581-597
-
-
Marks, J.D.1
Hoogenboom, H.R.2
Bonnert, T.P.3
McCafferty, J.4
Griffiths, A.D.5
Winter, G.6
-
35
-
-
0029891214
-
Screening of phage antibody libraries
-
Harrison, J. L., Williams, S. C., Winter, G., and Nissim, A. Screening of phage antibody libraries. Methods Enzymol., 267: 83-109, 1996.
-
(1996)
Methods Enzymol.
, vol.267
, pp. 83-109
-
-
Harrison, J.L.1
Williams, S.C.2
Winter, G.3
Nissim, A.4
-
36
-
-
0026699293
-
Selection of phage antibodies by binding affinity. Mimicking affinity maturation
-
Hawkins, R. E., Russell, S. J., and Winter, G. Selection of phage antibodies by binding affinity. Mimicking affinity maturation. J. Mol. Biol., 226: 889-896, 1992.
-
(1992)
J. Mol. Biol.
, vol.226
, pp. 889-896
-
-
Hawkins, R.E.1
Russell, S.J.2
Winter, G.3
-
37
-
-
0031081318
-
Designing and optimizing library selection strategies for generating high-affinity antibodies
-
Hoogenboom, H. R. Designing and optimizing library selection strategies for generating high-affinity antibodies. Trends Biotechnol., 15: 62-70, 1997.
-
(1997)
Trends Biotechnol.
, vol.15
, pp. 62-70
-
-
Hoogenboom, H.R.1
-
38
-
-
0342437532
-
Production of human antibody repertoires in transgenic mice
-
Bruggemann, M., and Taussig, M. J. Production of human antibody repertoires in transgenic mice. Curr. Opin. Biotechnol., 8: 455-458, 1997.
-
(1997)
Curr. Opin. Biotechnol.
, vol.8
, pp. 455-458
-
-
Bruggemann, M.1
Taussig, M.J.2
-
39
-
-
0027962758
-
Making antibodies by phage display technology
-
Winter, G., Griffiths, A. D., Hawkins, R. E., and Hoogenboom, H. R. Making antibodies by phage display technology. Annu. Rev. Immunol., 12: 433-455, 1994.
-
(1994)
Annu. Rev. Immunol.
, vol.12
, pp. 433-455
-
-
Winter, G.1
Griffiths, A.D.2
Hawkins, R.E.3
Hoogenboom, H.R.4
-
40
-
-
0025226085
-
Phage antibodies: Filamentous phage displaying antibody variable domains
-
McCafferty, J., Griffiths, A. D., Winter, G., and Chiswell, D. J. Phage antibodies: filamentous phage displaying antibody variable domains. Nature (Lond.), 348: 552-554, 1990.
-
(1990)
Nature (Lond.)
, vol.348
, pp. 552-554
-
-
McCafferty, J.1
Griffiths, A.D.2
Winter, G.3
Chiswell, D.J.4
-
42
-
-
0345193910
-
Affinity maturation of antibodies using phage display
-
H. R. McCafferty, H. R. Hoogenboom, and D. J. Chiswell (eds.). Oxford, United Kingdom: IRL Press
-
Johnson, K. S., and Hawkins, R. J. Affinity maturation of antibodies using phage display. In: H. R. McCafferty, H. R. Hoogenboom, and D. J. Chiswell (eds.), Antibody Engineering: A Practical Approach, pp. 41-58. Oxford, United Kingdom: IRL Press, 1996.
-
(1996)
Antibody Engineering: A Practical Approach
, pp. 41-58
-
-
Johnson, K.S.1
Hawkins, R.J.2
-
43
-
-
9544250404
-
Clinical evidence of efficient tumor targeting based on single-chain Fv antibody selected from a combinatorial library
-
Begent, R. H., Verhaar, M. J., Chester, K. A., Casey, J. L., Green, A. J., Napier, M. P., Hope-Stone, L. D., Cushen, N., Keep, P. A., Johnson, C. J., Hawkins, R. E., Hilson, A. J., and Robson, L. Clinical evidence of efficient tumor targeting based on single-chain Fv antibody selected from a combinatorial library. Nat. Med., 2: 979-984, 1996.
-
(1996)
Nat. Med.
, vol.2
, pp. 979-984
-
-
Begent, R.H.1
Verhaar, M.J.2
Chester, K.A.3
Casey, J.L.4
Green, A.J.5
Napier, M.P.6
Hope-Stone, L.D.7
Cushen, N.8
Keep, P.A.9
Johnson, C.J.10
Hawkins, R.E.11
Hilson, A.J.12
Robson, L.13
-
44
-
-
0032006660
-
Increased affinity leads to improved selective tumor delivery of single-chain Fv antibodies
-
Adams, G. P., Schier, R., Marshall, K., Wolf, E. J., McCall, A. M., Marks, J. D., and Weiner, L. M. Increased affinity leads to improved selective tumor delivery of single-chain Fv antibodies. Cancer Res., 58: 485-490, 1998.
-
(1998)
Cancer Res.
, vol.58
, pp. 485-490
-
-
Adams, G.P.1
Schier, R.2
Marshall, K.3
Wolf, E.J.4
McCall, A.M.5
Marks, J.D.6
Weiner, L.M.7
-
45
-
-
0029844521
-
Phage libraries: A new route to clinically useful antibodies
-
Marks, C., and Marks, J. D. Phage libraries: a new route to clinically useful antibodies. N. Engl. J. Med., 335: 730-733, 1996.
-
(1996)
N. Engl. J. Med.
, vol.335
, pp. 730-733
-
-
Marks, C.1
Marks, J.D.2
-
46
-
-
0030575802
-
Isolation of picomolar affinity anti-c-erbB-2 single-chain Fv by molecular evolution of the complementarity determining regions in the center of the antibody binding site
-
Schier, R., McCall, A., Adams, G. P., Marshall, K. W., Merritt, H., Yim, M., Crawford, R. S., Weiner, L. M., Marks, C., and Marks, J. D. Isolation of picomolar affinity anti-c-erbB-2 single-chain Fv by molecular evolution of the complementarity determining regions in the center of the antibody binding site. J. Mol. Biol., 263: 551-567, 1996.
-
(1996)
J. Mol. Biol.
, vol.263
, pp. 551-567
-
-
Schier, R.1
McCall, A.2
Adams, G.P.3
Marshall, K.W.4
Merritt, H.5
Yim, M.6
Crawford, R.S.7
Weiner, L.M.8
Marks, C.9
Marks, J.D.10
-
47
-
-
0030952417
-
Yttrium-90/Indium-111-DOTA-peptide-chimeric L6: Pharmacokinetics, dosimetry and initial results in patients with incurable breast cancer
-
DeNardo, S. J., Richman, C. M., Goldstein, D. S., Shen, S., Salako, Q. A., Kukis, D. L., Meares, C. F., Yuan, A., Welborn, J. L., and DeNardo, G. L. Yttrium-90/Indium-111-DOTA-peptide-chimeric L6: pharmacokinetics, dosimetry and initial results in patients with incurable breast cancer. Anticancer Res., 17: 1735-1744, 1997.
-
(1997)
Anticancer Res.
, vol.17
, pp. 1735-1744
-
-
DeNardo, S.J.1
Richman, C.M.2
Goldstein, D.S.3
Shen, S.4
Salako, Q.A.5
Kukis, D.L.6
Meares, C.F.7
Yuan, A.8
Welborn, J.L.9
DeNardo, G.L.10
-
48
-
-
14444270630
-
67Cu-2IT-BAT-Lym-1 for fractionated radioimmunotherapy of non-Hodgkin's lymphoma: A pilot study
-
67Cu-2IT-BAT-Lym-1 for fractionated radioimmunotherapy of non-Hodgkin's lymphoma: a pilot study. Anticancer Res., 18: 2779-2788, 1998.
-
(1998)
Anticancer Res.
, vol.18
, pp. 2779-2788
-
-
DeNardo, G.L.1
DeNardo, S.J.2
Kukis, D.L.3
O'Donnell, R.T.4
Shen, S.5
Goldstein, D.S.6
Kroger, L.A.7
Salako, Q.8
DeNardo, D.A.9
Mirick, G.R.10
Mausner, L.F.11
Srivastava, S.C.12
Meares, C.F.13
-
49
-
-
0027217164
-
Rapid PCR construction of a gene containing Lym-1 antibody variable regions
-
Shi, X. B., Gumerlock, P. H., Wellman, A. A., Meares, C. F., DeNardo, G. L., Meyers, F. J., and DeNardo, S. J. Rapid PCR construction of a gene containing Lym-1 antibody variable regions. PCR Methods Applications, 3: 46-53, 1993.
-
(1993)
PCR Methods Applications
, vol.3
, pp. 46-53
-
-
Shi, X.B.1
Gumerlock, P.H.2
Wellman, A.A.3
Meares, C.F.4
DeNardo, G.L.5
Meyers, F.J.6
DeNardo, S.J.7
-
50
-
-
0031759837
-
131I-Lym-1 antibody for fractionated radioimmunotherapy of non-Hodgkin's lymphoma
-
131I-Lym-1 antibody for fractionated radioimmunotherapy of non-Hodgkin's lymphoma. J. Clin. Oncol., 16: 3246-3256, 1998.
-
(1998)
J. Clin. Oncol.
, vol.16
, pp. 3246-3256
-
-
DeNardo, G.L.1
DeNardo, S.J.2
Goldstein, D.S.3
Kroger, L.A.4
Lamborn, K.R.5
Levy, N.B.6
McGahan, J.P.7
Salako, Q.A.8
Shen, S.9
Lewis, J.P.10
-
51
-
-
7844233336
-
131I-Lym-1 antibody
-
131I-Lym-1 antibody. Cancer Biother. Radiopharm., 13: 239-254, 1998.
-
(1998)
Cancer Biother. Radiopharm.
, vol.13
, pp. 239-254
-
-
DeNardo, G.L.1
DeNardo, S.J.2
Lamborn, K.R.3
Goldstein, D.S.4
Levy, N.B.5
Lewis, J.P.6
O'Grady, L.F.7
Raventos, A.8
Kroger, L.A.9
Macey, D.J.10
McGahan, J.P.11
Mills, S.L.12
Shen, S.13
-
52
-
-
0032586390
-
Efficient recombination of Lym-1 scFv gene using multiple doubly-restricted DNA fragments
-
Shi, X. B., Gumerlock, P. H., Kroger, L. A., DeNardo, G. L., and DeNardo, S. J. Efficient recombination of Lym-1 scFv gene using multiple doubly-restricted DNA fragments. Cancer Biother. Radiopharm., 14: 139-143, 1999.
-
(1999)
Cancer Biother. Radiopharm.
, vol.14
, pp. 139-143
-
-
Shi, X.B.1
Gumerlock, P.H.2
Kroger, L.A.3
DeNardo, G.L.4
DeNardo, S.J.5
-
53
-
-
0016756272
-
Continuous culture of fused cells secreting antibody of predefined specificity
-
Kohler, G., and Milstein, C. Continuous culture of fused cells secreting antibody of predefined specificity. Nature (Lond.), 256: 495-497, 1975.
-
(1975)
Nature (Lond.)
, vol.256
, pp. 495-497
-
-
Kohler, G.1
Milstein, C.2
-
54
-
-
0025733874
-
Haemodynamic and transport barriers to the treatment of solid tumours
-
Jain, R. K. Haemodynamic and transport barriers to the treatment of solid tumours. Int. J. Radiat. Biol., 60: 85-100, 1991.
-
(1991)
Int. J. Radiat. Biol.
, vol.60
, pp. 85-100
-
-
Jain, R.K.1
-
55
-
-
0026528230
-
Miniantibodies: Use of amphipathic helices to produce functional, flexibly linked dimeric Fv fragments with high avidity in Escherichia coli
-
Pack, P., and Pluckthun, A. Miniantibodies: use of amphipathic helices to produce functional, flexibly linked dimeric Fv fragments with high avidity in Escherichia coli. Biochemistry, 31: 1579-1584, 1992.
-
(1992)
Biochemistry
, vol.31
, pp. 1579-1584
-
-
Pack, P.1
Pluckthun, A.2
-
56
-
-
0027442660
-
Improved bivalent miniantibodies, with identical avidity as whole antibodies, produced by high cell density fermentation of Escherichia coli
-
Pack, P., Schroechk, V., Knupfer, U., Wenderoth, R., Riesenberg, D., and Pluckthun, A. Improved bivalent miniantibodies, with identical avidity as whole antibodies, produced by high cell density fermentation of Escherichia coli. Biotechnology, 11: 1271-1277, 1993.
-
(1993)
Biotechnology
, vol.11
, pp. 1271-1277
-
-
Pack, P.1
Schroechk, V.2
Knupfer, U.3
Wenderoth, R.4
Riesenberg, D.5
Pluckthun, A.6
-
57
-
-
0029890636
-
Minibody: A novel engineered anti-carcinoembryonic antigen antibody fragment (single-chain-Fv-Ch3) which exhibits rapid, high-level targeting of xenografts
-
Hu, S. Z., Raubitschek, A., Sherman, A., Williams, L. E., Wong, J. Y., Shively, J. E., and Wu, A. M. Minibody: a novel engineered anti-carcinoembryonic antigen antibody fragment (single-chain-Fv-Ch3) which exhibits rapid, high-level targeting of xenografts. Cancer Res., 56: 3055-3061, 1996.
-
(1996)
Cancer Res.
, vol.56
, pp. 3055-3061
-
-
Hu, S.Z.1
Raubitschek, A.2
Sherman, A.3
Williams, L.E.4
Wong, J.Y.5
Shively, J.E.6
Wu, A.M.7
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