메뉴 건너뛰기




Volumn 58, Issue 3, 1998, Pages 485-490

Increased affinity leads to improved selective tumor delivery of single- chain Fv antibodies

Author keywords

[No Author keywords available]

Indexed keywords

EPITOPE; IMMUNOGLOBULIN FRAGMENT; IMMUNOGLOBULIN G;

EID: 0032006660     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (214)

References (31)
  • 1
    • 0025190073 scopus 로고
    • Comparison of tumor targeting in nude mice by murine monoclonal antibodies directed against different human colorectal cancer antigens
    • Sharkey, R. M., Gold, D. V., Aninipot, R., Vagg, R., Ballance, C., Newman, E. S., Ostella, F., Hansen, H. J., and Goldenberg, D. M. Comparison of tumor targeting in nude mice by murine monoclonal antibodies directed against different human colorectal cancer antigens. Cancer Res., 50: 828s-834s, 1990.
    • (1990) Cancer Res. , vol.50
    • Sharkey, R.M.1    Gold, D.V.2    Aninipot, R.3    Vagg, R.4    Ballance, C.5    Newman, E.S.6    Ostella, F.7    Hansen, H.J.8    Goldenberg, D.M.9
  • 2
    • 0025300384 scopus 로고
    • Interstitial transport of rabbit and sheep antibodies in normal and neoplastic tissues
    • Clauss, M. A., and Jain, R. K. Interstitial transport of rabbit and sheep antibodies in normal and neoplastic tissues. Cancer Res., 50: 3487-3492, 1990.
    • (1990) Cancer Res. , vol.50 , pp. 3487-3492
    • Clauss, M.A.1    Jain, R.K.2
  • 7
    • 0026327378 scopus 로고
    • Construction, binding properties, metabolism, and targeting of a single-chain Fv derived from the pancarcinoma monoclonal antibody CC49
    • Milenic, D. E., Yokota, T., Filpula, D. R., Finkelman, M. A. J., Dodd, S. W., Wood, J. F., Whitlow, M., Snow, P., and Schlom, J. Construction, binding properties, metabolism, and targeting of a single-chain Fv derived from the pancarcinoma monoclonal antibody CC49. Cancer Res., 51: 6363-6371, 1991.
    • (1991) Cancer Res. , vol.51 , pp. 6363-6371
    • Milenic, D.E.1    Yokota, T.2    Filpula, D.R.3    Finkelman, M.A.J.4    Dodd, S.W.5    Wood, J.F.6    Whitlow, M.7    Snow, P.8    Schlom, J.9
  • 8
    • 0026684815 scopus 로고
    • Rapid tumor penetration of a single-chain Fv and comparison with other immunoglobulin forms
    • Yokota, T., Milenic, D., Whitlow, M., and Schlom, J. Rapid tumor penetration of a single-chain Fv and comparison with other immunoglobulin forms. Cancer Res., 52: 3402-3408, 1992.
    • (1992) Cancer Res. , vol.52 , pp. 3402-3408
    • Yokota, T.1    Milenic, D.2    Whitlow, M.3    Schlom, J.4
  • 9
    • 0027249714 scopus 로고
    • Microautoradiographic analysis of the normal organ distribution of radioiodinated single-chain Fv and other immunoglobulin forms
    • Yokota, T., Milenic, D. E., Whitlow, M., Wood, J. F., Hubert, S. L., and Schlom, J. Microautoradiographic analysis of the normal organ distribution of radioiodinated single-chain Fv and other immunoglobulin forms. Cancer Res., 53: 3776-3783, 1993.
    • (1993) Cancer Res. , vol.53 , pp. 3776-3783
    • Yokota, T.1    Milenic, D.E.2    Whitlow, M.3    Wood, J.F.4    Hubert, S.L.5    Schlom, J.6
  • 10
    • 0026641471 scopus 로고
    • Molecular evolution of proteins on filamentous phage: Mimicking the strategy of the immune system
    • Marks, J. D., Hoogenboom, H. R., Griffiths, A. D., and Winter, G. Molecular evolution of proteins on filamentous phage: mimicking the strategy of the immune system. J. Biol. Chem., 267: 16007-16010, 1992.
    • (1992) J. Biol. Chem. , vol.267 , pp. 16007-16010
    • Marks, J.D.1    Hoogenboom, H.R.2    Griffiths, A.D.3    Winter, G.4
  • 11
    • 0029844521 scopus 로고    scopus 로고
    • Phage libraries: A new route to clinically useful antibodies
    • Marks, C., and Marks, J. D. Phage libraries: a new route to clinically useful antibodies. N. Engl. J. Med., 335: 730-733, 1996.
    • (1996) N. Engl. J. Med. , vol.335 , pp. 730-733
    • Marks, C.1    Marks, J.D.2
  • 12
    • 0029294084 scopus 로고
    • In vitro and in vivo characterization of a human anti-c-erbB-2 single- chain Fv isolated from a filamentous phage antibody library
    • Schier, R., Marks, J. D., Wolf, E. J., Apell, G., Huston, J. S., Weiner, L. M., and Adams, G. P. In vitro and in vivo characterization of a human anti-c-erbB-2 single- chain Fv isolated from a filamentous phage antibody library. Immunotechnology, 1: 63-71, 1995.
    • (1995) Immunotechnology , vol.1 , pp. 63-71
    • Schier, R.1    Marks, J.D.2    Wolf, E.J.3    Apell, G.4    Huston, J.S.5    Weiner, L.M.6    Adams, G.P.7
  • 13
    • 0030575802 scopus 로고    scopus 로고
    • Isolation of picomolar affinity anti-c-erbB2 single-chain Fv by molecular evolution of the complementarity determining regions in the centre of the antibody combining site
    • Schier, R., McCall, A., Adams, G. P., Marshall, K., Yim, M., Merritt, H., Crawford, R. S., Weiner, L. M., Marks, C., and Marks, J. D. Isolation of picomolar affinity anti-c-erbB2 single-chain Fv by molecular evolution of the complementarity determining regions in the centre of the antibody combining site. J. Mol. Biol., 263: 551-567, 1996.
    • (1996) J. Mol. Biol. , vol.263 , pp. 551-567
    • Schier, R.1    McCall, A.2    Adams, G.P.3    Marshall, K.4    Yim, M.5    Merritt, H.6    Crawford, R.S.7    Weiner, L.M.8    Marks, C.9    Marks, J.D.10
  • 15
    • 0025254304 scopus 로고
    • Regulated expression of foreign genes fused to lac: Control by glucose levels in growth medium
    • De Bellis, D., and Schwartz, I. Regulated expression of foreign genes fused to lac: control by glucose levels in growth medium. Nucleic Acids Res., 18: 1311, 1990.
    • (1990) Nucleic Acids Res. , vol.18 , pp. 1311
    • De Bellis, D.1    Schwartz, I.2
  • 16
    • 0025944567 scopus 로고
    • A surface expression vector for antibody screening
    • Amst.
    • Breitling, S. D., Seehaus, T., Klewinghaus, I., and Little, M. A surface expression vector for antibody screening. Gene (Amst.), 104: 147-153, 1991.
    • (1991) Gene , vol.104 , pp. 147-153
    • Breitling, S.D.1    Seehaus, T.2    Klewinghaus, I.3    Little, M.4
  • 17
    • 0023781763 scopus 로고
    • Genetic approach to facilitate purification of recombinant proteins with a novel metal chelate adsorbent
    • Hochuli, E., Bannwarth, W., Dobeli, H., Gentz, R., and Stuber, D. Genetic approach to facilitate purification of recombinant proteins with a novel metal chelate adsorbent. Bio/Technology, 6: 1321-1325, 1988.
    • (1988) Bio/Technology , vol.6 , pp. 1321-1325
    • Hochuli, E.1    Bannwarth, W.2    Dobeli, H.3    Gentz, R.4    Stuber, D.5
  • 20
    • 0021512252 scopus 로고
    • Conjugation of antibodies with bifunctional chelating agents: Isothiocyanate and bromoacetamide reagents, methods of analysis, and subsequent addition of metal ions
    • Meares, C. F., McCall, M. J., Reardan, D. T., Goodwin, D. A., Diamanti, P. I., and McTigue, M. Conjugation of antibodies with bifunctional chelating agents: isothiocyanate and bromoacetamide reagents, methods of analysis, and subsequent addition of metal ions. Anal. Biochem., 142: 68-78, 1984.
    • (1984) Anal. Biochem. , vol.142 , pp. 68-78
    • Meares, C.F.1    McCall, M.J.2    Reardan, D.T.3    Goodwin, D.A.4    Diamanti, P.I.5    McTigue, M.6
  • 21
    • 0014949207 scopus 로고
    • Cleavage of structural proteins during the assembly of the head of bacteriophage T4
    • Laemmli, U. K. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature (Lond.), 227: 680-685, 1970.
    • (1970) Nature (Lond.) , vol.227 , pp. 680-685
    • Laemmli, U.K.1
  • 23
    • 0025376171 scopus 로고
    • A modeling analysis of monoclonal antibody percolation through tumors: A binding site barrier
    • Fujimori, K., Covell, D. G., Fletcher, J. E., and Weinstein, J. N. A modeling analysis of monoclonal antibody percolation through tumors: a binding site barrier. J. Nucl. Med., 31: 1191-1198, 1990.
    • (1990) J. Nucl. Med. , vol.31 , pp. 1191-1198
    • Fujimori, K.1    Covell, D.G.2    Fletcher, J.E.3    Weinstein, J.N.4
  • 24
    • 0026739369 scopus 로고
    • Micropharmacology of monoclonal antibodies in solid tumors: Direct experimental evidence for a binding site barrier
    • Juweid, M., Neumann, R., Paik, C., Perez-Bacete, M. J., Sato, J., van Osdol, W., and Weinstein, J. N. Micropharmacology of monoclonal antibodies in solid tumors: direct experimental evidence for a binding site barrier. Cancer Res., 52: 5144-5153, 1992.
    • (1992) Cancer Res. , vol.52 , pp. 5144-5153
    • Juweid, M.1    Neumann, R.2    Paik, C.3    Perez-Bacete, M.J.4    Sato, J.5    Van Osdol, W.6    Weinstein, J.N.7
  • 25
    • 0023730850 scopus 로고
    • Radioimmmunolocalization of human carcinoma xenografts with B72.3 second generation monoclonal antibodies
    • Colcher, D., Minelli, F. M., Roselli, M., Muraro, R., Simpson-Milenic, D., and Schlom, J. Radioimmmunolocalization of human carcinoma xenografts with B72.3 second generation monoclonal antibodies. Cancer Res., 48: 4597-4603, 1988.
    • (1988) Cancer Res. , vol.48 , pp. 4597-4603
    • Colcher, D.1    Minelli, F.M.2    Roselli, M.3    Muraro, R.4    Simpson-Milenic, D.5    Schlom, J.6
  • 26
    • 0027398643 scopus 로고
    • Comparative dual label study of first and second generation antitumor-associated glycoprotein-72 monoclonal antibodies in colorectal cancer patients
    • Gallinger, S., Reilly, R. M., Kirsh, J. C., Odze, R. D., Schmocker, B. J., Hay, K., Polihronis, J., Damani, M. T., Shpitz, B., and Stern, H. S. Comparative dual label study of first and second generation antitumor-associated glycoprotein-72 monoclonal antibodies in colorectal cancer patients. Cancer Res., 53: 271-278, 1993.
    • (1993) Cancer Res. , vol.53 , pp. 271-278
    • Gallinger, S.1    Reilly, R.M.2    Kirsh, J.C.3    Odze, R.D.4    Schmocker, B.J.5    Hay, K.6    Polihronis, J.7    Damani, M.T.8    Shpitz, B.9    Stern, H.S.10
  • 30
    • 0022946258 scopus 로고
    • In vitro and in vivo tumor models for studies of distribution of radiolabeled monoclonal antibodies and fragments
    • Buchegger, F., Halpern, S. E., Sutherland, R. M., Schreyer, M., and Mach, J-P. In vitro and in vivo tumor models for studies of distribution of radiolabeled monoclonal antibodies and fragments. Nuklearmedizin, 25: 207-209, 1986.
    • (1986) Nuklearmedizin , vol.25 , pp. 207-209
    • Buchegger, F.1    Halpern, S.E.2    Sutherland, R.M.3    Schreyer, M.4    Mach, J.-P.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.