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Volumn 728, Issue 1, 1996, Pages 1-6

Inhibition of free radical production or free radical scavenging protects from the excitotoxic cell death mediated by glutamate in cultures of cerebellar granule neurons

Author keywords

Antioxidant; Apoptosis; Enzyme inhibitor; Free radical; Glutamate toxicity; Granule neuron; Necrosis; Neuroprotection

Indexed keywords

6 CYANO 7 NITRO 2,3 QUINOXALINEDIONE; 6 NITRO 7 SULFAMOYLBENZO[F]QUINOXALINE 2,3 DIONE; ALLOPURINOL; ALPHA TOCOPHEROL; ARGININE; ASCORBIC ACID; AURINTRICARBOXYLIC ACID; BUTYLATED HYDROXYANISOLE; CYCLOHEXIMIDE; DIZOCILPINE; ENZYME INHIBITOR; FREE RADICAL; GLUTAMIC ACID; MAGNESIUM; N(G) NITROARGININE; NEUROPROTECTIVE AGENT; NITRIC OXIDE SYNTHASE; PHOSPHOLIPASE A2; XANTHINE OXIDASE;

EID: 0030597992     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/0006-8993(96)00382-4     Document Type: Article
Times cited : (109)

References (33)
  • 1
    • 0028793257 scopus 로고
    • Glutamate-induced neuronal death: A succession of necrosis or apoptosis depending on mitochondrial function
    • [1] Ankarcrona, M., Dypbukt, J.M., Bonfoco, E., Zhivotovsky, B., Orrenius, S., Lipton, S.A. and Nicotera, P., Glutamate-induced neuronal death: a succession of necrosis or apoptosis depending on mitochondrial function, Neuron, 15 (1995) 961-973.
    • (1995) Neuron , vol.15 , pp. 961-973
    • Ankarcrona, M.1    Dypbukt, J.M.2    Bonfoco, E.3    Zhivotovsky, B.4    Orrenius, S.5    Lipton, S.A.6    Nicotera, P.7
  • 2
    • 0028936986 scopus 로고
    • Bioenergetic and oxidative stress in neurodegenerative diseases
    • [2] Bowling, A.C. and Beal, M.F., Bioenergetic and oxidative stress in neurodegenerative diseases. Life Sci., 56 (1995) 1151-1171.
    • (1995) Life Sci. , vol.56 , pp. 1151-1171
    • Bowling, A.C.1    Beal, M.F.2
  • 3
    • 0024093449 scopus 로고
    • Glutamate neurotoxicity and diseases of the nervous system
    • [3] Choi, D.W., Glutamate neurotoxicity and diseases of the nervous system, Neuron, 1 (1988) 623-634.
    • (1988) Neuron , vol.1 , pp. 623-634
    • Choi, D.W.1
  • 4
    • 0028118703 scopus 로고
    • Trolox attenuates cortical neuronal injury induced by iron, ultraviolet light, glucose deprivation, or AMPA
    • [4] Chow, H.S., Lynch III, J.J., Rose, K. and Choi, D.W., Trolox attenuates cortical neuronal injury induced by iron, ultraviolet light, glucose deprivation, or AMPA, Brain Res., 639 (1994) 102-108.
    • (1994) Brain Res. , vol.639 , pp. 102-108
    • Chow, H.S.1    Lynch J.J. III2    Rose, K.3    Choi, D.W.4
  • 6
    • 0027686249 scopus 로고
    • Oxidative stress, glutamate and neurodegenerative disorders
    • [6] Coyle, J.T. and Puttfarcken, P., Oxidative stress, glutamate and neurodegenerative disorders. Science, 262 (1993) 689-693.
    • (1993) Science , vol.262 , pp. 689-693
    • Coyle, J.T.1    Puttfarcken, P.2
  • 8
    • 0027215170 scopus 로고
    • Glutamate-induced neuronal death is not a programmed cell death in cerebellar culture
    • [8] Dessi, F., Charriault-Marlangue, C., Khrestchatisky, M. and Ben-Ari, Y., Glutamate-induced neuronal death is not a programmed cell death in cerebellar culture, J. Neurochem., 60 (1993) 1953-1955.
    • (1993) J. Neurochem. , vol.60 , pp. 1953-1955
    • Dessi, F.1    Charriault-Marlangue, C.2    Khrestchatisky, M.3    Ben-Ari, Y.4
  • 9
    • 0027939882 scopus 로고
    • Increased synthesis of specific proteins during glutamate-induced neural death in cerebellar culture
    • [9] Dessi, F., Ben-Ari, Y. and Charriault-Marlangue, C., Increased synthesis of specific proteins during glutamate-induced neural death in cerebellar culture. Brain Res., 654 (1994) 27-33.
    • (1994) Brain Res. , vol.654 , pp. 27-33
    • Dessi, F.1    Ben-Ari, Y.2    Charriault-Marlangue, C.3
  • 10
    • 0023197336 scopus 로고
    • Mechanism of kainate toxicity to cerebellar neurons in vitro is analogous to reperfusion tissue injury
    • [10] Dykens, J.A., Stern, A. and Trenkner, E., Mechanism of kainate toxicity to cerebellar neurons in vitro is analogous to reperfusion tissue injury, J. Neurochem., 49 (1987) 1222-1228.
    • (1987) J. Neurochem. , vol.49 , pp. 1222-1228
    • Dykens, J.A.1    Stern, A.2    Trenkner, E.3
  • 11
    • 0026667538 scopus 로고
    • Antagonist of the NMDA receptor and allopurinol protect the olfactory cortex but not the striatum after intracerebral injection of kainic acid
    • [11] Facchinetti, F., Virgili, M., Contestabile, A. and Barnabei, O., Antagonist of the NMDA receptor and allopurinol protect the olfactory cortex but not the striatum after intracerebral injection of kainic acid. Brain Res., 585 (1992) 330-334.
    • (1992) Brain Res. , vol.585 , pp. 330-334
    • Facchinetti, F.1    Virgili, M.2    Contestabile, A.3    Barnabei, O.4
  • 12
    • 0012053105 scopus 로고
    • Neurochemical evaluation of the protective effects of mannitol and alpha-tocopherol in rats injected intrastriatally with kainic acid
    • [12] Facchinetti, F. and Contestabile, A., Neurochemical evaluation of the protective effects of mannitol and alpha-tocopherol in rats injected intrastriatally with kainic acid. Neurodegeneration, 2 (1993) 123-127.
    • (1993) Neurodegeneration , vol.2 , pp. 123-127
    • Facchinetti, F.1    Contestabile, A.2
  • 13
    • 0023244774 scopus 로고
    • The role of depolarization in the survival and differentiation of cerebellar granule cells in culture
    • [13] Gallo. V., Kingsbury, A., Balázs, R. and Jorgensen, O.S., The role of depolarization in the survival and differentiation of cerebellar granule cells in culture, J. Neurosci., 7 (1987) 2203-2213.
    • (1987) J. Neurosci. , vol.7 , pp. 2203-2213
    • Gallo, V.1    Kingsbury, A.2    Balázs, R.3    Jorgensen, O.S.4
  • 14
    • 0028856368 scopus 로고
    • NMDA receptor activation produces concurrent generation of nitric oxide and reactive oxygen species: Implication for cell death
    • [14] Gunasekar, P.G., Kanthasamy, A.G., Borowitz, J.L. and Isom, G.E., NMDA receptor activation produces concurrent generation of nitric oxide and reactive oxygen species: implication for cell death. J. Neurochem., 65 (1995) 2016-2021.
    • (1995) J. Neurochem. , vol.65 , pp. 2016-2021
    • Gunasekar, P.G.1    Kanthasamy, A.G.2    Borowitz, J.L.3    Isom, G.E.4
  • 15
    • 0026754574 scopus 로고
    • Reactive oxygen species and the central nervous system
    • [15] Halliwell, B., Reactive oxygen species and the central nervous system, J. Neurochem., 59 (1992) 1609-1623.
    • (1992) J. Neurochem. , vol.59 , pp. 1609-1623
    • Halliwell, B.1
  • 16
    • 0027376374 scopus 로고
    • Inibition of nitric oxide formation does not protect murine cortical cell cultures from N-methyl-D-aspartate neurotoxicity
    • [16] Hewett, S.J., Corbett, J.A., McDaniel, M.L. and Choi, D.W., Inibition of nitric oxide formation does not protect murine cortical cell cultures from N-methyl-D-aspartate neurotoxicity, Brain Res., 625 (1993) 337-341.
    • (1993) Brain Res. , vol.625 , pp. 337-341
    • Hewett, S.J.1    Corbett, J.A.2    McDaniel, M.L.3    Choi, D.W.4
  • 17
    • 0023221068 scopus 로고
    • Quantitative determination of glutamate mediated cortical neuronal injury in cell culture by lactate dehydrogenase efflux assay
    • [17] Koh, J.Y. and Choi, D.W., Quantitative determination of glutamate mediated cortical neuronal injury in cell culture by lactate dehydrogenase efflux assay, J. Neurosci. Methods, 20 (1987) 83-90.
    • (1987) J. Neurosci. Methods , vol.20 , pp. 83-90
    • Koh, J.Y.1    Choi, D.W.2
  • 19
    • 0027380609 scopus 로고
    • Nitric oxide, superoxide and peroxynitrite: Putative mediators of NMDA-induced cell death in cerebellar granule cells
    • [19] Lafon-Cazal, M., Culcasi, M., Gaven, F., Pietri, S. and Bockaert, J., Nitric oxide, superoxide and peroxynitrite: putative mediators of NMDA-induced cell death in cerebellar granule cells, Neuropharmacol., 32 (1993) 1259-1266.
    • (1993) Neuropharmacol. , vol.32 , pp. 1259-1266
    • Lafon-Cazal, M.1    Culcasi, M.2    Gaven, F.3    Pietri, S.4    Bockaert, J.5
  • 20
    • 0027221998 scopus 로고
    • NMDA-dependent superoxide production and neurotoxicity
    • [20] Lafon-Cazal, M., Pietri, S., Culcasi, M. and Bockaert, J., NMDA-dependent superoxide production and neurotoxicity, Nature, 364 (1993) 535-537.
    • (1993) Nature , vol.364 , pp. 535-537
    • Lafon-Cazal, M.1    Pietri, S.2    Culcasi, M.3    Bockaert, J.4
  • 21
    • 0025674468 scopus 로고
    • N-Methyl-D-aspartate-sensitive glutamate receptors induce calcium-mediated arachidonic acid release in primary cultures of cerebellar granule cells
    • [21] Lazarewicz, J.W., Wroblewski, J.T. and Costa, E., N-Methyl-D-aspartate-sensitive glutamate receptors induce calcium-mediated arachidonic acid release in primary cultures of cerebellar granule cells, J. Neurochem., 55 (1990) 1875-1881.
    • (1990) J. Neurochem. , vol.55 , pp. 1875-1881
    • Lazarewicz, J.W.1    Wroblewski, J.T.2    Costa, E.3
  • 22
    • 0019732954 scopus 로고
    • The cooperative interaction between vitamin E and vitamin C in suppression of peroxidation of membrane phospholipids
    • [22] Leung, H.W., Vang, M.J. and Mavis, R.D., The cooperative interaction between vitamin E and vitamin C in suppression of peroxidation of membrane phospholipids, Biochim. Biophys. Acta, 664 (1981) 266-272.
    • (1981) Biochim. Biophys. Acta , vol.664 , pp. 266-272
    • Leung, H.W.1    Vang, M.J.2    Mavis, R.D.3
  • 23
    • 0023125256 scopus 로고
    • The physiology of excitatory amino acids in the vertebrate central nervous system
    • [23] Mayer, M.L. and Westbrook, G.L., The physiology of excitatory amino acids in the vertebrate central nervous system, Prog. Neurobiol., 28 (1987) 197-276.
    • (1987) Prog. Neurobiol. , vol.28 , pp. 197-276
    • Mayer, M.L.1    Westbrook, G.L.2
  • 24
    • 0026775370 scopus 로고
    • Blockade of nitric oxide formation does not prevent glutamate-induced neurotoxicity in neuronal cultures from rat hippocampus
    • [24] Pawels, P.J. and Leysen, J.E., Blockade of nitric oxide formation does not prevent glutamate-induced neurotoxicity in neuronal cultures from rat hippocampus, Neurosci. Lett., 143 (1992) 27-30.
    • (1992) Neurosci. Lett. , vol.143 , pp. 27-30
    • Pawels, P.J.1    Leysen, J.E.2
  • 25
    • 0026703425 scopus 로고
    • Dissociation of nitric oxide generation and kainate-mediated neuronal degeneration in primary cultures of rat cerebellar granule cells
    • [25] Puttfarcken, P.S., Lyons, W.E. and Coyle, J.T., Dissociation of nitric oxide generation and kainate-mediated neuronal degeneration in primary cultures of rat cerebellar granule cells, Neuropharmacology, 31 (1992) 565-575.
    • (1992) Neuropharmacology , vol.31 , pp. 565-575
    • Puttfarcken, P.S.1    Lyons, W.E.2    Coyle, J.T.3
  • 26
    • 0027295849 scopus 로고
    • Kainic acid-induced lipid peroxidation: Protection with butylated hydroxytoluene and U78517F in primary cultures of cerebellar granule cells
    • [26] Puttfarcken, P.S., Getz, R.L. and Coyle, J.T., Kainic acid-induced lipid peroxidation: protection with butylated hydroxytoluene and U78517F in primary cultures of cerebellar granule cells, Brain Res., 624 (1993) 223-232.
    • (1993) Brain Res. , vol.624 , pp. 223-232
    • Puttfarcken, P.S.1    Getz, R.L.2    Coyle, J.T.3
  • 27
    • 0027315347 scopus 로고
    • Delayed production of nitric oxide contributes to NMDA-mediated neuronal damage
    • [27] Reif, D.W., Delayed production of nitric oxide contributes to NMDA-mediated neuronal damage, Neuroreport., 4 (1993) 566-568.
    • (1993) Neuroreport. , vol.4 , pp. 566-568
    • Reif, D.W.1
  • 28
    • 0027933495 scopus 로고
    • Growth conditions differentially modulate the vulnerability of developing cerebellar granule cells to excitatory amino acis
    • [28] Resink., A., Hack, N., Boer, G.J. and Balazs, R., Growth conditions differentially modulate the vulnerability of developing cerebellar granule cells to excitatory amino acis, Brain Res., 655 (1994) 222-232.
    • (1994) Brain Res. , vol.655 , pp. 222-232
    • Resink, A.1    Hack, N.2    Boer, G.J.3    Balazs, R.4
  • 29
    • 0025139268 scopus 로고
    • Serum and depolarizing agents cause acute neurotoxicity in cultured cerebellar granule cells: Role of the glutamate receptor
    • [29] Schramm, M., Eimerl, S. and Costa, E., Serum and depolarizing agents cause acute neurotoxicity in cultured cerebellar granule cells: role of the glutamate receptor, Proc. Natl. Acad. Sci. USA, 87 (1990) 1193-1197.
    • (1990) Proc. Natl. Acad. Sci. USA , vol.87 , pp. 1193-1197
    • Schramm, M.1    Eimerl, S.2    Costa, E.3
  • 30
    • 0028586834 scopus 로고
    • Cycloheximide and actinomycin D block the toxic effect of glutamic acid on PC12 cells
    • [30] Serghini, R., Froissard, P., Sola, B. and Duval, D., Cycloheximide and actinomycin D block the toxic effect of glutamic acid on PC12 cells, Neuroreport, 6 (1994) 29-32.
    • (1994) Neuroreport , vol.6 , pp. 29-32
    • Serghini, R.1    Froissard, P.2    Sola, B.3    Duval, D.4
  • 32
    • 0028129035 scopus 로고
    • Potential therapeutics of vitamin E (tocopherol) in AIDS and HIV
    • [32] Wang, Y. and Watson, R.R., Potential therapeutics of vitamin E (tocopherol) in AIDS and HIV, Drugs, 48 (1994) 327-338.
    • (1994) Drugs , vol.48 , pp. 327-338
    • Wang, Y.1    Watson, R.R.2
  • 33
    • 0028965929 scopus 로고
    • Excitotoxicity at both NMDA and non-NMDA glutamate receptors is antagonized by aurintricarboxylic acid: Evidence for differing mechanisms of action
    • [33] Zeevalk, G.D., Schoepp, D. and Nicklas, W.J., Excitotoxicity at both NMDA and non-NMDA glutamate receptors is antagonized by aurintricarboxylic acid: evidence for differing mechanisms of action, J. Neurochem., 64 (1995) 1749-1758.
    • (1995) J. Neurochem. , vol.64 , pp. 1749-1758
    • Zeevalk, G.D.1    Schoepp, D.2    Nicklas, W.J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.